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Items: 5

1.

Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells.

Buenaventura T, Bitsi S, Laughlin WE, Burgoyne T, Lyu Z, Oqua AI, Norman H, McGlone ER, Klymchenko AS, Corrêa IR Jr, Walker A, Inoue A, Hanyaloglu A, Grimes J, Koszegi Z, Calebiro D, Rutter GA, Bloom SR, Jones B, Tomas A.

PLoS Biol. 2019 Aug 20;17(8):e3000097. doi: 10.1371/journal.pbio.3000097. eCollection 2019 Aug.

2.

Targeting GLP-1 receptor trafficking to improve agonist efficacy.

Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen BM, Scott R, Goldin R, Angkathunyakul N, Corrêa IR Jr, Bosco D, Johnson PR, Piemonti L, Marchetti P, Shapiro AMJ, Cochran BJ, Hanyaloglu AC, Inoue A, Tan T, Rutter GA, Tomas A, Bloom SR.

Nat Commun. 2018 Apr 23;9(1):1602. doi: 10.1038/s41467-018-03941-2.

3.

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology.

Podewin T, Ast J, Broichhagen J, Fine NHF, Nasteska D, Leippe P, Gailer M, Buenaventura T, Kanda N, Jones BJ, M'Kadmi C, Baneres JL, Marie J, Tomas A, Trauner D, Hoffmann-Röder A, Hodson DJ.

ACS Cent Sci. 2018 Feb 28;4(2):166-179. doi: 10.1021/acscentsci.7b00237. Epub 2018 Jan 16.

4.

Control of insulin secretion by GLP-1.

Jones B, Bloom SR, Buenaventura T, Tomas A, Rutter GA.

Peptides. 2018 Feb;100:75-84. doi: 10.1016/j.peptides.2017.12.013. Review.

5.

A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells.

Buenaventura T, Kanda N, Douzenis PC, Jones B, Bloom SR, Chabosseau P, Corrêa IR Jr, Bosco D, Piemonti L, Marchetti P, Johnson PR, Shapiro AMJ, Rutter GA, Tomas A.

Diabetes. 2018 Mar;67(3):385-399. doi: 10.2337/db17-0639. Epub 2017 Dec 28.

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