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Items: 1 to 50 of 185

1.

Large extracellular vesicles: Size matters in tumor progression.

Ciardiello C, Migliorino R, Leone A, Budillon A.

Cytokine Growth Factor Rev. 2020 Feb;51:69-74. doi: 10.1016/j.cytogfr.2019.12.007. Epub 2019 Dec 31. Review.

2.

Structural analysis of human SEPHS2 protein, a selenocysteine machinery component, over-expressed in triple negative breast cancer.

Nunziata C, Polo A, Sorice A, Capone F, Accardo M, Guerriero E, Marino FZ, Orditura M, Budillon A, Costantini S.

Sci Rep. 2019 Nov 6;9(1):16131. doi: 10.1038/s41598-019-52718-0.

3.

Structure-function relationship of an Urokinase Receptor-derived peptide which inhibits the Formyl Peptide Receptor type 1 activity.

Minopoli M, Polo A, Ragone C, Ingangi V, Ciliberto G, Pessi A, Sarno S, Budillon A, Costantini S, Carriero MV.

Sci Rep. 2019 Aug 21;9(1):12169. doi: 10.1038/s41598-019-47900-3.

4.

Correction to: Histone deacetylase inhibitor ITF2357 (givinostat) reverts transformed phenotype and counteracts stemness in in vitro and in vivo models of human glioblastoma.

Marampon F, Leoni F, Mancini A, Pietrantoni I, Codenotti S, Ferella L, Megiorni F, Porro G, Galbiati E, Pozzi P, Mascagni P, Budillon A, Maggio R, Tombolini V, Fanzani A, Gravina GL, Festuccia C.

J Cancer Res Clin Oncol. 2019 Sep;145(9):2411. doi: 10.1007/s00432-019-02980-6.

PMID:
31346710
5.

Perspectives in melanoma: meeting report from the Melanoma Bridge (November 29th-1 December 1st, 2018, Naples, Italy).

Ascierto PA, Agarwala SS, Botti G, Budillon A, Davies MA, Dummer R, Ernstoff M, Ferrone S, Formenti S, Gajewski TF, Garbe C, Hamid O, Lo RS, Luke JJ, Michielin O, Palmieri G, Zitvogel L, Marincola FM, Masucci G, Caracò C, Thurin M, Puzanov I.

J Transl Med. 2019 Jul 22;17(1):234. doi: 10.1186/s12967-019-1979-z.

6.

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation.

Ciardiello C, Leone A, Lanuti P, Roca MS, Moccia T, Minciacchi VR, Minopoli M, Gigantino V, De Cecio R, Rippa M, Petti L, Capone F, Vitagliano C, Milone MR, Pucci B, Lombardi R, Iannelli F, Di Gennaro E, Bruzzese F, Marchisio M, Carriero MV, Di Vizio D, Budillon A.

J Exp Clin Cancer Res. 2019 Jul 18;38(1):317. doi: 10.1186/s13046-019-1317-6.

7.

Identification and Targeting of Stem Cell-Activated Pathways in Cancer Therapy.

Budillon A, Curley S, Fusco R, Mancini R.

Stem Cells Int. 2019 Jun 4;2019:8549020. doi: 10.1155/2019/8549020. eCollection 2019. No abstract available.

8.

Implication for Cancer Stem Cells in Solid Cancer Chemo-Resistance: Promising Therapeutic Strategies Based on the Use of HDAC Inhibitors.

Roca MS, Di Gennaro E, Budillon A.

J Clin Med. 2019 Jun 26;8(7). pii: E912. doi: 10.3390/jcm8070912. Review.

9.

Vorinostat Potentiates 5-Fluorouracil/Cisplatin Combination by Inhibiting Chemotherapy-Induced EGFR Nuclear Translocation and Increasing Cisplatin Uptake.

Piro G, Roca MS, Bruzzese F, Carbone C, Iannelli F, Leone A, Volpe MG, Budillon A, Di Gennaro E.

Mol Cancer Ther. 2019 Aug;18(8):1405-1417. doi: 10.1158/1535-7163.MCT-18-1117. Epub 2019 Jun 12.

PMID:
31189612
10.

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis.

Elgendy M, Cirò M, Hosseini A, Weiszmann J, Mazzarella L, Ferrari E, Cazzoli R, Curigliano G, DeCensi A, Bonanni B, Budillon A, Pelicci PG, Janssens V, Ogris M, Baccarini M, Lanfrancone L, Weckwerth W, Foiani M, Minucci S.

Cancer Cell. 2019 May 13;35(5):798-815.e5. doi: 10.1016/j.ccell.2019.03.007. Epub 2019 Apr 25.

PMID:
31031016
11.

18F-FDG PET/CT Is an Early Predictor of Pathologic Tumor Response and Survival After Preoperative Radiochemotherapy with Bevacizumab in High-Risk Locally Advanced Rectal Cancer.

Avallone A, Aloj L, Pecori B, Caracò C, De Stefano A, Tatangelo F, Silvestro L, Granata V, Bianco F, Romano C, Di Gennaro F, Budillon A, Petrillo A, Muto P, Botti G, Delrio P, Lastoria S.

J Nucl Med. 2019 Nov;60(11):1560-1568. doi: 10.2967/jnumed.118.222604. Epub 2019 Mar 15.

PMID:
30877175
12.

Effects of α-zearalenol on the metabolome of two breast cancer cell lines by 1H-NMR approach.

Nittoli AC, Costantini S, Sorice A, Capone F, Ciarcia R, Marzocco S, Budillon A, Severino L.

Metabolomics. 2018 Feb 14;14(3):33. doi: 10.1007/s11306-018-1330-3.

PMID:
30830360
13.

Primary Endovascular Repair of the Ascending Aorta.

Borrello B, Carino D, Agostinelli A, Budillon AM, Nicolini F.

Innovations (Phila). 2018 Nov/Dec;13(6):448-450. doi: 10.1097/IMI.0000000000000561.

PMID:
30540589
14.

The Crosstalk between Cancer Stem Cells and Microenvironment Is Critical for Solid Tumor Progression: The Significant Contribution of Extracellular Vesicles.

Ciardiello C, Leone A, Budillon A.

Stem Cells Int. 2018 Nov 5;2018:6392198. doi: 10.1155/2018/6392198. eCollection 2018. Review.

15.

Histone deacetylase inhibitor ITF2357 (givinostat) reverts transformed phenotype and counteracts stemness in in vitro and in vivo models of human glioblastoma.

Marampon F, Leoni F, Mancini A, Pietrantoni I, Codenotti S, Ferella L, Megiorni F, Porro G, Galbiati E, Pozzi P, Mascagni P, Budillon A, Maggio R, Tombolini V, Fanzani A, Gravina GL, Festuccia C.

J Cancer Res Clin Oncol. 2019 Feb;145(2):393-409. doi: 10.1007/s00432-018-2800-8. Epub 2018 Nov 24. Erratum in: J Cancer Res Clin Oncol. 2019 Sep;145(9):2411.

PMID:
30474756
16.

Evaluation of Aflatoxin M1 Effects on the Metabolomic and Cytokinomic Profiling of a Hepatoblastoma Cell Line.

Marchese S, Sorice A, Ariano A, Florio S, Budillon A, Costantini S, Severino L.

Toxins (Basel). 2018 Oct 28;10(11). pii: E436. doi: 10.3390/toxins10110436.

17.

Novel pathways involved in cisplatin resistance identified by a proteomics approach in non-small-cell lung cancer cells.

Milone MR, Lombardi R, Roca MS, Bruzzese F, Addi L, Pucci B, Budillon A.

J Cell Physiol. 2019 Jun;234(6):9077-9092. doi: 10.1002/jcp.27585. Epub 2018 Oct 26.

PMID:
30362533
18.

Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma.

Fattore L, Ruggiero CF, Pisanu ME, Liguoro D, Cerri A, Costantini S, Capone F, Acunzo M, Romano G, Nigita G, Mallardo D, Ragone C, Carriero MV, Budillon A, Botti G, Ascierto PA, Mancini R, Ciliberto G.

Cell Death Differ. 2019 Jul;26(7):1267-1282. doi: 10.1038/s41418-018-0205-5. Epub 2018 Sep 25.

19.

Identifying a panel of genes/proteins/miRNAs modulated by arsenicals in bladder, prostate, kidney cancers.

Polo A, Marchese S, De Petro G, Montella M, Ciliberto G, Budillon A, Costantini S.

Sci Rep. 2018 Jul 10;8(1):10395. doi: 10.1038/s41598-018-28739-6.

20.

Survival analysis of a multicentre, randomized phase 3 study on the optimization of the combination of bevacizumab with FOLFOX/OXXEL in patients with metastatic colorectal cancer (mCRC).

Avallone A, Nasti G, Rosati G, Carlomagno C, Romano C, Bilancia D, De Stefano A, Silvestro L, Ottaiano A, Cassata A, Bianco F, Izzo F, Delrio P, De Gennaro E, Casaretti R, Tafuto S, Albino V, Pace U, Lastoria S, Gallo C, Budillon A, Piccirillo M.

Ann Oncol. 2018 Jun;29 Suppl 5:v74. doi: 10.1093/annonc/mdy151.262. Epub 2020 Jan 7. No abstract available.

21.

The Effect of Light Exposure at Night (LAN) on Carcinogenesis via Decreased Nocturnal Melatonin Synthesis.

Giudice A, Crispo A, Grimaldi M, Polo A, Bimonte S, Capunzo M, Amore A, D'Arena G, Cerino P, Budillon A, Botti G, Costantini S, Montella M.

Molecules. 2018 May 29;23(6). pii: E1308. doi: 10.3390/molecules23061308. Review.

22.

A standardized flow cytometry network study for the assessment of circulating endothelial cell physiological ranges.

Lanuti P, Simeone P, Rotta G, Almici C, Avvisati G, Azzaro R, Bologna G, Budillon A, Di Cerbo M, Di Gennaro E, Di Martino ML, Diodato A, Doretto P, Ercolino E, Falda A, Gregorj C, Leone A, Losa F, Malara N, Marini M, Mastroroberto P, Mollace V, Morelli M, Muggianu E, Musolino G, Neva A, Pierdomenico L, Pinna S, Piovani G, Roca MS, Russo D, Scotti L, Tirindelli MC, Trunzo V, Venturella R, Vitagliano C, Zullo F, Marchisio M, Miscia S.

Sci Rep. 2018 Apr 11;8(1):5823. doi: 10.1038/s41598-018-24234-0.

23.

Toxigenic effects of two benthic diatoms upon grazing activity of the sea urchin: morphological, metabolomic and de novo transcriptomic analysis.

Ruocco N, Costantini S, Zupo V, Lauritano C, Caramiello D, Ianora A, Budillon A, Romano G, Nuzzo G, D'Ippolito G, Fontana A, Costantini M.

Sci Rep. 2018 Apr 4;8(1):5622. doi: 10.1038/s41598-018-24023-9.

24.

HDAC inhibition potentiates immunotherapy in triple negative breast cancer.

Terranova-Barberio M, Thomas S, Ali N, Pawlowska N, Park J, Krings G, Rosenblum MD, Budillon A, Munster PN.

Oncotarget. 2017 Dec 12;8(69):114156-114172. doi: 10.18632/oncotarget.23169. eCollection 2017 Dec 26.

25.

Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53.

Terranova-Barberio M, Pecori B, Roca MS, Imbimbo S, Bruzzese F, Leone A, Muto P, Delrio P, Avallone A, Budillon A, Di Gennaro E.

J Exp Clin Cancer Res. 2017 Dec 6;36(1):177. doi: 10.1186/s13046-017-0647-5.

26.

Targeting Mevalonate Pathway in Cancer Treatment: Repurposing of Statins.

Iannelli F, Lombardi R, Milone MR, Pucci B, De Rienzo S, Budillon A, Bruzzese F.

Recent Pat Anticancer Drug Discov. 2018;13(2):184-200. doi: 10.2174/1574892812666171129141211. Review.

PMID:
29189178
27.

An interaction network approach to study the correlation between endocrine disrupting chemicals and breast cancer.

Polo A, Nittoli C, Crispo A, Langastro T, Cocco S, Severino L, De Laurentiis M, Ciliberto G, Montella M, Budillon A, Costantini S.

Mol Biosyst. 2017 Nov 21;13(12):2687-2696. doi: 10.1039/c7mb00489c.

PMID:
29072741
28.

Conformational analysis of the human chemokine receptor CXCR3.

Raucci R, Polo A, Budillon A, Colonna G, Costantini S.

Mol Immunol. 2017 Dec;92:76-86. doi: 10.1016/j.molimm.2017.10.010. Epub 2017 Oct 17.

PMID:
29054054
29.

Environment and bladder cancer: molecular analysis by interaction networks.

Polo A, Crispo A, Cerino P, Falzone L, Candido S, Giudice A, De Petro G, Ciliberto G, Montella M, Budillon A, Costantini S.

Oncotarget. 2017 May 26;8(39):65240-65252. doi: 10.18632/oncotarget.18222. eCollection 2017 Sep 12.

30.

Evaluating the Effects of an Organic Extract from the Mediterranean Sponge Geodia cydonium on Human Breast Cancer Cell Lines.

Costantini S, Guerriero E, Teta R, Capone F, Caso A, Sorice A, Romano G, Ianora A, Ruocco N, Budillon A, Costantino V, Costantini M.

Int J Mol Sci. 2017 Oct 9;18(10). pii: E2112. doi: 10.3390/ijms18102112.

31.

Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches.

Leone A, Roca MS, Ciardiello C, Costantini S, Budillon A.

Oxid Med Cell Longev. 2017;2017:2597581. doi: 10.1155/2017/2597581. Epub 2017 Jul 9. Review.

32.

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.

Noto A, De Vitis C, Pisanu ME, Roscilli G, Ricci G, Catizone A, Sorrentino G, Chianese G, Taglialatela-Scafati O, Trisciuoglio D, Del Bufalo D, Di Martile M, Di Napoli A, Ruco L, Costantini S, Jakopin Z, Budillon A, Melino G, Del Sal G, Ciliberto G, Mancini R.

Oncogene. 2017 Aug 10;36(32):4671-4672. doi: 10.1038/onc.2017.212. Epub 2017 Jun 19.

PMID:
28628115
33.

Different strategies for mechanical VENTilation during CardioPulmonary Bypass (CPBVENT 2014): study protocol for a randomized controlled trial.

Bignami E, Guarnieri M, Saglietti F, Maglioni EM, Scolletta S, Romagnoli S, De Paulis S, Paternoster G, Trumello C, Meroni R, Scognamiglio A, Budillon AM, Pota V, Zangrillo A, Alfieri O.

Trials. 2017 Jun 7;18(1):264. doi: 10.1186/s13063-017-2008-2.

34.

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.

Noto A, De Vitis C, Pisanu ME, Roscilli G, Ricci G, Catizone A, Sorrentino G, Chianese G, Taglialatela-Scafati O, Trisciuoglio D, Del Bufalo D, Di Martile M, Di Napoli A, Ruco L, Costantini S, Jakopin Z, Budillon A, Melino G, Del Sal G, Ciliberto G, Mancini R.

Oncogene. 2017 Aug 10;36(32):4573-4584. doi: 10.1038/onc.2017.75. Epub 2017 Apr 3. Erratum in: Oncogene. 2017 Jun 19;:.

PMID:
28368399
35.

Sequential PET/CT with [18F]-FDG Predicts Pathological Tumor Response to Preoperative Short Course Radiotherapy with Delayed Surgery in Patients with Locally Advanced Rectal Cancer Using Logistic Regression Analysis.

Pecori B, Lastoria S, Caracò C, Celentani M, Tatangelo F, Avallone A, Rega D, De Palma G, Mormile M, Budillon A, Muto P, Bianco F, Aloj L, Petrillo A, Delrio P.

PLoS One. 2017 Jan 6;12(1):e0169462. doi: 10.1371/journal.pone.0169462. eCollection 2017.

36.

Phase II clinical study of valproic acid plus cisplatin and cetuximab in recurrent and/or metastatic squamous cell carcinoma of Head and Neck-V-CHANCE trial.

Caponigro F, Di Gennaro E, Ionna F, Longo F, Aversa C, Pavone E, Maglione MG, Di Marzo M, Muto P, Cavalcanti E, Petrillo A, Sandomenico F, Maiolino P, D'Aniello R, Botti G, De Cecio R, Losito NS, Scala S, Trotta A, Zotti AI, Bruzzese F, Daponte A, Calogero E, Montano M, Pontone M, De Feo G, Perri F, Budillon A.

BMC Cancer. 2016 Nov 25;16(1):918.

37.

Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles.

Russo A, Maiolino S, Pagliara V, Ungaro F, Tatangelo F, Leone A, Scalia G, Budillon A, Quaglia F, Russo G.

Oncotarget. 2016 Nov 29;7(48):79670-79687. doi: 10.18632/oncotarget.13216.

38.

Potential Anticancer Effects of Polyphenols from Chestnut Shell Extracts: Modulation of Cell Growth, and Cytokinomic and Metabolomic Profiles.

Sorice A, Siano F, Capone F, Guerriero E, Picariello G, Budillon A, Ciliberto G, Paolucci M, Costantini S, Volpe MG.

Molecules. 2016 Oct 21;21(10). pii: E1411.

39.

Tissue transglutaminase (TG2) is involved in the resistance of cancer cells to the histone deacetylase (HDAC) inhibitor vorinostat.

Carbone C, Di Gennaro E, Piro G, Milone MR, Pucci B, Caraglia M, Budillon A.

Amino Acids. 2017 Mar;49(3):517-528. doi: 10.1007/s00726-016-2338-5. Epub 2016 Oct 19.

PMID:
27761756
40.

Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents.

Zotti AI, Di Gennaro E, Corvino A, Frecentese F, Magli E, Perissutti E, Cirino G, Roviezzo F, Terranova-Barberio M, Iannelli F, Caliendo G, Santagada V, Fiorino F, Budillon A, Severino B.

Anticancer Agents Med Chem. 2017;17(7):973-981. doi: 10.2174/1871520616666160926120904.

PMID:
27671294
41.

Proteomic characterization of peroxisome proliferator-activated receptor-γ (PPARγ) overexpressing or silenced colorectal cancer cells unveils a novel protein network associated with an aggressive phenotype.

Milone MR, Pucci B, Colangelo T, Lombardi R, Iannelli F, Colantuoni V, Sabatino L, Budillon A.

Mol Oncol. 2016 Oct;10(8):1344-62. doi: 10.1016/j.molonc.2016.07.006. Epub 2016 Jul 25.

42.

Management of non-small cell lung cancer in the era of personalized medicine.

Rocco G, Morabito A, Leone A, Muto P, Fiore F, Budillon A.

Int J Biochem Cell Biol. 2016 Sep;78:173-179. doi: 10.1016/j.biocel.2016.07.011. Epub 2016 Jul 15. Review.

PMID:
27425397
43.

Biotin-targeted Pluronic(®) P123/F127 mixed micelles delivering niclosamide: A repositioning strategy to treat drug-resistant lung cancer cells.

Russo A, Pellosi DS, Pagliara V, Milone MR, Pucci B, Caetano W, Hioka N, Budillon A, Ungaro F, Russo G, Quaglia F.

Int J Pharm. 2016 Sep 10;511(1):127-139. doi: 10.1016/j.ijpharm.2016.06.118. Epub 2016 Jun 29.

PMID:
27374195
44.

Impact of Subsequent Therapies on Outcome of the FIRE-3/AIO KRK0306 Trial.

Avallone A, Budillon A.

J Clin Oncol. 2016 May 1;34(13):1564. doi: 10.1200/JCO.2015.66.1512. Epub 2016 Mar 7. No abstract available.

PMID:
26951321
45.

Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer.

Colangelo T, Polcaro G, Ziccardi P, Pucci B, Muccillo L, Galgani M, Fucci A, Milone MR, Budillon A, Santopaolo M, Votino C, Pancione M, Piepoli A, Mazzoccoli G, Binaschi M, Bigioni M, Maggi CA, Fassan M, Laudanna C, Matarese G, Sabatino L, Colantuoni V.

Cell Death Dis. 2016 Feb 25;7:e2120. doi: 10.1038/cddis.2016.28.

46.

The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells.

Colangelo T, Polcaro G, Ziccardi P, Muccillo L, Galgani M, Pucci B, Milone MR, Budillon A, Santopaolo M, Mazzoccoli G, Matarese G, Sabatino L, Colantuoni V.

Cell Death Dis. 2016 Feb 25;7:e2108. doi: 10.1038/cddis.2016.29.

47.

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression.

Ciardiello C, Roca MS, Noto A, Bruzzese F, Moccia T, Vitagliano C, Di Gennaro E, Ciliberto G, Roscilli G, Aurisicchio L, Marra E, Mancini R, Budillon A, Leone A.

Oncotarget. 2016 Apr 12;7(15):19559-74. doi: 10.18632/oncotarget.7195.

48.

A randomized phase 3 study on the optimization of the combination of bevacizumab with FOLFOX/OXXEL in the treatment of patients with metastatic colorectal cancer-OBELICS (Optimization of BEvacizumab scheduLIng within Chemotherapy Scheme).

Avallone A, Piccirillo MC, Aloj L, Nasti G, Delrio P, Izzo F, Di Gennaro E, Tatangelo F, Granata V, Cavalcanti E, Maiolino P, Bianco F, Aprea P, De Bellis M, Pecori B, Rosati G, Carlomagno C, Bertolini A, Gallo C, Romano C, Leone A, Caracò C, de Lutio di Castelguidone E, Daniele G, Catalano O, Botti G, Petrillo A, Romano GM, Iaffaioli VR, Lastoria S, Perrone F, Budillon A.

BMC Cancer. 2016 Feb 8;16:69. doi: 10.1186/s12885-016-2102-y.

49.

Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression.

Terranova-Barberio M, Roca MS, Zotti AI, Leone A, Bruzzese F, Vitagliano C, Scogliamiglio G, Russo D, D'Angelo G, Franco R, Budillon A, Di Gennaro E.

Oncotarget. 2016 Feb 16;7(7):7715-31. doi: 10.18632/oncotarget.6802.

50.

Support Detection for SAR Tomographic Reconstructions from Compressive Measurements.

Budillon A, Schirinzi G.

ScientificWorldJournal. 2015;2015:949807. doi: 10.1155/2015/949807. Epub 2015 Oct 1.

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