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Items: 1 to 50 of 56

1.

Pharmacologic targeting of the ATX/LPA axis attenuates bleomycin-induced pulmonary fibrosis.

Ninou I, Kaffe E, Müller S, Budd DC, Stevenson CS, Ullmer C, Aidinis V.

Pulm Pharmacol Ther. 2018 Oct;52:32-40. doi: 10.1016/j.pupt.2018.08.003. Epub 2018 Sep 7.

PMID:
30201409
2.

Transforming Growth Factor Beta Gene Signatures are Spatially Enriched in Keloid Tissue Biopsies and Ex vivo-Cultured Keloid Fibroblasts.

Taylor A, Budd DC, Shih B, Seifert O, Beaton A, Wright T, Dempsey M, Kelly F, Egerton J, Marshall RP, Aston N, Bayat A.

Acta Derm Venereol. 2017 Jan 4;97(1):10-16. doi: 10.2340/00015555-2462.

3.

Development of Autotaxin Inhibitors: An Overview of the Patent and Primary Literature.

Castagna D, Budd DC, Macdonald SJ, Jamieson C, Watson AJ.

J Med Chem. 2016 Jun 23;59(12):5604-21. doi: 10.1021/acs.jmedchem.5b01599. Epub 2016 Jan 28. Review.

PMID:
26745766
4.

Discovery of novel non-carboxylic acid 5-amino-4-cyanopyrazole derivatives as potent and highly selective LPA1R antagonists.

Sidduri A, Budd DC, Fuentes ME, Lambros T, Ren Y, Roongta V, Schoenfeld RC, Gillespie P, Stevenson CS, Truitt T, Qian Y.

Bioorg Med Chem Lett. 2014 Sep 15;24(18):4450-4454. doi: 10.1016/j.bmcl.2014.08.001. Epub 2014 Aug 8.

PMID:
25155385
5.

Development of lysophosphatidic acid pathway modulators as therapies for fibrosis.

Budd DC, Qian Y.

Future Med Chem. 2013 Oct;5(16):1935-52. doi: 10.4155/fmc.13.154. Review.

PMID:
24175745
6.

Assessment of Brd4 inhibition in idiopathic pulmonary fibrosis lung fibroblasts and in vivo models of lung fibrosis.

Tang X, Peng R, Phillips JE, Deguzman J, Ren Y, Apparsundaram S, Luo Q, Bauer CM, Fuentes ME, DeMartino JA, Tyagi G, Garrido R, Hogaboam CM, Denton CP, Holmes AM, Kitson C, Stevenson CS, Budd DC.

Am J Pathol. 2013 Aug;183(2):470-9. doi: 10.1016/j.ajpath.2013.04.020. Epub 2013 Jun 10.

PMID:
23759512
7.

Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease.

Peng R, Sridhar S, Tyagi G, Phillips JE, Garrido R, Harris P, Burns L, Renteria L, Woods J, Chen L, Allard J, Ravindran P, Bitter H, Liang Z, Hogaboam CM, Kitson C, Budd DC, Fine JS, Bauer CM, Stevenson CS.

PLoS One. 2013;8(4):e59348. doi: 10.1371/journal.pone.0059348. Epub 2013 Apr 2.

8.

Targeting the epithelial cells in fibrosis: a new concept for an old disease.

Moll S, Chaykovska L, Meier M, Budd DC, Formentini I, Pomposiello S, Prunotto M.

Drug Discov Today. 2013 Jun;18(11-12):582-91. doi: 10.1016/j.drudis.2013.01.006. Epub 2013 Jan 22. Review.

PMID:
23348679
9.

BET bromodomain proteins mediate downstream signaling events following growth factor stimulation in human lung fibroblasts and are involved in bleomycin-induced pulmonary fibrosis.

Tang X, Peng R, Ren Y, Apparsundaram S, Deguzman J, Bauer CM, Hoffman AF, Hamilton S, Liang Z, Zeng H, Fuentes ME, Demartino JA, Kitson C, Stevenson CS, Budd DC.

Mol Pharmacol. 2013 Jan;83(1):283-93. doi: 10.1124/mol.112.081661. Epub 2012 Oct 31.

PMID:
23115324
10.

Comparing the differential effects of LPA on the barrier function of human pulmonary endothelial cells.

Ren Y, Guo L, Tang X, Apparsundaram S, Kitson C, Deguzman J, Fuentes ME, Coyle L, Majmudar R, Allard J, Truitt T, Hamid R, Chen Y, Qian Y, Budd DC.

Microvasc Res. 2013 Jan;85:59-67. doi: 10.1016/j.mvr.2012.10.004. Epub 2012 Oct 16.

PMID:
23084965
11.

Discovery of highly selective and orally active lysophosphatidic acid receptor-1 antagonists with potent activity on human lung fibroblasts.

Qian Y, Hamilton M, Sidduri A, Gabriel S, Ren Y, Peng R, Kondru R, Narayanan A, Truitt T, Hamid R, Chen Y, Zhang L, Fretland AJ, Sanchez RA, Chang KC, Lucas M, Schoenfeld RC, Laine D, Fuentes ME, Stevenson CS, Budd DC.

J Med Chem. 2012 Sep 13;55(17):7920-39. doi: 10.1021/jm301022v. Epub 2012 Aug 29.

PMID:
22894757
12.

From acute injury to chronic disease: pathophysiological hypothesis of an epithelial/mesenchymal crosstalk alteration in CKD.

Prunotto M, Budd DC, Meier M, Formentini I, Hartmann G, Pomposiello S, Moll S.

Nephrol Dial Transplant. 2012 Oct;27 Suppl 3:iii43-50. doi: 10.1093/ndt/gfs283. Epub 2012 Jul 10. Review.

PMID:
22785113
13.

Targeting TGFβ superfamily ligand accessory proteins as novel therapeutics for chronic lung disorders.

Budd DC, Holmes AM.

Pharmacol Ther. 2012 Sep;135(3):279-91. doi: 10.1016/j.pharmthera.2012.06.001. Epub 2012 Jun 18. Review.

PMID:
22722064
14.

Epithelial-mesenchymal crosstalk alteration in kidney fibrosis.

Prunotto M, Budd DC, Gabbiani G, Meier M, Formentini I, Hartmann G, Pomposiello S, Moll S.

J Pathol. 2012 Oct;228(2):131-47. doi: 10.1002/path.4049. Epub 2012 Aug 20. Review.

PMID:
22570261
15.

BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines.

Davies RJ, Holmes AM, Deighton J, Long L, Yang X, Barker L, Walker C, Budd DC, Upton PD, Morrell NW.

Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15;302(6):L604-15. doi: 10.1152/ajplung.00309.2011. Epub 2012 Jan 6.

16.

Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II.

Burton VJ, Holmes AM, Ciuclan LI, Robinson A, Roger JS, Jarai G, Pearce AC, Budd DC.

Blood. 2011 Oct 27;118(17):4750-8. doi: 10.1182/blood-2011-05-347393. Epub 2011 Sep 7.

17.

Bone morphogenetic protein receptor II regulates pulmonary artery endothelial cell barrier function.

Burton VJ, Ciuclan LI, Holmes AM, Rodman DM, Walker C, Budd DC.

Blood. 2011 Jan 6;117(1):333-41. doi: 10.1182/blood-2010-05-285973. Epub 2010 Aug 19.

18.

Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension.

Soon E, Holmes AM, Treacy CM, Doughty NJ, Southgate L, Machado RD, Trembath RC, Jennings S, Barker L, Nicklin P, Walker C, Budd DC, Pepke-Zaba J, Morrell NW.

Circulation. 2010 Aug 31;122(9):920-7. doi: 10.1161/CIRCULATIONAHA.109.933762. Epub 2010 Aug 16.

PMID:
20713898
19.

Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrotaline.

Thomas M, Docx C, Holmes AM, Beach S, Duggan N, England K, Leblanc C, Lebret C, Schindler F, Raza F, Walker C, Crosby A, Davies RJ, Morrell NW, Budd DC.

Am J Pathol. 2009 Feb;174(2):380-9. doi: 10.2353/ajpath.2009.080565. Epub 2008 Dec 30.

20.

A single point mutation (N514Y) in the human M3 muscarinic acetylcholine receptor reveals differences in the properties of antagonists: evidence for differential inverse agonism.

Dowling MR, Willets JM, Budd DC, Charlton SJ, Nahorski SR, Challiss RA.

J Pharmacol Exp Ther. 2006 Jun;317(3):1134-42. Epub 2006 Feb 17.

PMID:
16489127
21.

Signalling of the M3-muscarinic receptor to the anti-apoptotic pathway.

Budd DC, Spragg EJ, Ridd K, Tobin AB.

Biochem J. 2004 Jul 1;381(Pt 1):43-9.

22.

The anti-apoptotic response of the Gq/11-coupled muscarinic receptor family.

Tobin AB, Budd DC.

Biochem Soc Trans. 2003 Dec;31(Pt 6):1182-5. Review.

PMID:
14641022
23.

The C-terminal tail of the M3-muscarinic receptor possesses anti-apoptotic properties.

Budd DC, McDonald J, Emsley N, Cain K, Tobin AB.

J Biol Chem. 2003 May 23;278(21):19565-73. Epub 2003 Mar 20.

24.
25.

Phosphorylation and regulation of a Gq/11-coupled receptor by casein kinase 1alpha.

Budd DC, McDonald JE, Tobin AB.

J Biol Chem. 2000 Jun 30;275(26):19667-75.

26.
29.
30.

Presynaptic receptors and the control of glutamate exocytosis.

Sánchez-Prieto J, Budd DC, Herrero I, Vázquez E, Nicholls DG.

Trends Neurosci. 1996 Jun;19(6):235-9.

PMID:
8761959
32.
34.

Intraepidermal squamous carcinoma (Bowen's disease) of the nipple.

Venkataseshan VS, Budd DC, Un Kim D, Hutter RV.

Hum Pathol. 1994 Dec;25(12):1371-4.

PMID:
8001933
35.

The Tennessee Board of Medical Examiners.

Budd DC.

J Tenn Med Assoc. 1989 Jul;82(7):365-8. No abstract available.

PMID:
2779217
36.

Hyperparathyroidism masquerading as hyperemesis gravidarum.

Budd DC, Kumka MM, Suda AK, Fink DL.

N J Med. 1988 Oct;85(10):811-3. No abstract available.

PMID:
3226629
37.

Volvulus of the gallbladder.

Budd DC, Fink DL.

N J Med. 1985 Oct;82(10):803-4. No abstract available.

PMID:
3865067
38.

Reimplantation of the ampulla of Vater.

Budd DC, Fink DL.

Am J Surg. 1985 Sep;150(3):397-9.

PMID:
2412458
39.

Rectus muscle preservation in oblique incisions for cholecystectomy.

Fink DL, Budd DC.

Am Surg. 1984 Nov;50(11):628-9.

PMID:
6238562
40.

Chromic suture material as a nidus for common duct stone formation.

Fink DL, Budd DC.

Int Surg. 1983 Apr-Jun;68(2):151-2.

PMID:
6885295
41.

Squamous cell carcinoma of the thyroid.

Budd DC, Fink DL, Rashti MY, Woo TH.

J Med Soc N J. 1982 Oct;79(11):838-40. No abstract available.

PMID:
6960184
42.

Autosomal dominant mucoid colon carcinoma: a study of a case and a kindred.

Budd DC, Fink DL.

Am Surg. 1982 Apr;48(4):180-3. No abstract available.

PMID:
6282157
43.

Cholecystectomy with and without drainage. A randomized, prospective study of 300 patients.

Budd DC, Cochran RC, Fouty WJ Jr.

Am J Surg. 1982 Mar;143(3):307-9.

PMID:
7065351
44.

Mucoid colonic carcinoma as an autosomal-dominant inherited syndrome.

Budd DC, Fink DL.

Arch Surg. 1981 Jul;116(7):901-5.

PMID:
7259491
45.

Cysts of the adrenal gland.

Budd DC, Fink DL.

Am Surg. 1979 Oct;45(10):649-52. No abstract available.

PMID:
507537
46.

Gastric phytobezoar: still another postgastrectomy syndrome.

Budd DC, McCreary ML.

Am Surg. 1978 Feb;44(2):104-7. No abstract available.

PMID:
626436
47.

Surgical morbidity after mastectomy operations.

Budd DC, Cochran RC, Sturtz DL, Fouty WJ Jr.

Am J Surg. 1978 Feb;135(2):218-20.

PMID:
626296
48.

Thyroglossal duct cysts in the elderly.

Murphy JP, Budd DC.

South Med J. 1977 Oct;70(10):1247-8.

PMID:
910180
49.

Extramedullary plasmacytoma of the colon: a rare cause of intussusception.

Budd DC, Cochran RC, Metildi LA.

Am Surg. 1977 Aug;43(8):528-30. No abstract available.

PMID:
889191
50.

Familial retrocecal appendicitis.

Budd DC, Fouty WJ Jr.

Am J Surg. 1977 Jun;133(6):670-1.

PMID:
869116

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