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Items: 1 to 50 of 75

1.

Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.

Bencsik N, Pusztai S, Borbély S, Fekete A, Dülk M, Kis V, Pesti S, Vas V, Szűcs A, Buday L, Schlett K.

Sci Rep. 2019 Nov 14;9(1):16843. doi: 10.1038/s41598-019-53317-9.

2.

Analysis of Tks4 Knockout Mice Suggests a Role for Tks4 in Adipose Tissue Homeostasis in the Context of Beigeing.

Vas V, Háhner T, Kudlik G, Ernszt D, Kvell K, Kuti D, Kovács KJ, Tóvári J, Trexler M, Merő BL, Szeder B, Koprivanacz K, Buday L.

Cells. 2019 Aug 5;8(8). pii: E831. doi: 10.3390/cells8080831.

3.

Significance of the Tks4 scaffold protein in bone tissue homeostasis.

Vas V, Kovács T, Körmendi S, Bródy A, Kudlik G, Szeder B, Mező D, Kállai D, Koprivanacz K, Merő BL, Dülk M, Tóvári J, Vajdovich P, Şenel ŞN, Özcan I, Helyes Z, Dobó-Nagy C, Buday L.

Sci Rep. 2019 Apr 8;9(1):5781. doi: 10.1038/s41598-019-42250-6.

4.

Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.

Merő B, Radnai L, Gógl G, Tőke O, Leveles I, Koprivanacz K, Szeder B, Dülk M, Kudlik G, Vas V, Cserkaszky A, Sipeki S, Nyitray L, Vértessy BG, Buday L.

J Biol Chem. 2019 Mar 22;294(12):4608-4620. doi: 10.1074/jbc.RA118.004732. Epub 2019 Jan 18.

PMID:
30659095
5.

Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification.

Schuster S, Biri-Kovács B, Szeder B, Buday L, Gardi J, Szabó Z, Halmos G, Mező G.

Pharmaceutics. 2018 Nov 9;10(4). pii: E223. doi: 10.3390/pharmaceutics10040223.

6.

Disordered Regions of Mixed Lineage Leukemia 4 (MLL4) Protein Are Capable of RNA Binding.

Szabó B, Murvai N, Abukhairan R, Schád É, Kardos J, Szeder B, Buday L, Tantos Á.

Int J Mol Sci. 2018 Nov 5;19(11). pii: E3478. doi: 10.3390/ijms19113478.

7.

EGF Regulates the Interaction of Tks4 with Src through Its SH2 and SH3 Domains.

Dülk M, Szeder B, Glatz G, Merő BL, Koprivanacz K, Kudlik G, Vas V, Sipeki S, Cserkaszky A, Radnai L, Buday L.

Biochemistry. 2018 Jul 17;57(28):4186-4196. doi: 10.1021/acs.biochem.8b00084. Epub 2018 Jul 5.

PMID:
29928795
8.

Synthesis and in vitro biochemical evaluation of oxime bond-linked daunorubicin-GnRH-III conjugates developed for targeted drug delivery.

Schuster S, Biri-Kovács B, Szeder B, Farkas V, Buday L, Szabó Z, Halmos G, Mező G.

Beilstein J Org Chem. 2018 Apr 4;14:756-771. doi: 10.3762/bjoc.14.64. eCollection 2018.

9.

Dynamic control of RSK complexes by phosphoswitch-based regulation.

Gógl G, Biri-Kovács B, Póti ÁL, Vadászi H, Szeder B, Bodor A, Schlosser G, Ács A, Turiák L, Buday L, Alexa A, Nyitray L, Reményi A.

FEBS J. 2018 Jan;285(1):46-71. doi: 10.1111/febs.14311. Epub 2017 Nov 20.

10.

Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.

Ecsédi P, Kiss B, Gógl G, Radnai L, Buday L, Koprivanacz K, Liliom K, Leveles I, Vértessy B, Jeszenői N, Hetényi C, Schlosser G, Katona G, Nyitray L.

Structure. 2017 Aug 1;25(8):1195-1207.e5. doi: 10.1016/j.str.2017.06.001. Epub 2017 Jun 29.

11.

The transcriptional activity of hepatocyte nuclear factor 4 alpha is inhibited via phosphorylation by ERK1/2.

Vető B, Bojcsuk D, Bacquet C, Kiss J, Sipeki S, Martin L, Buday L, Bálint BL, Arányi T.

PLoS One. 2017 Feb 14;12(2):e0172020. doi: 10.1371/journal.pone.0172020. eCollection 2017.

12.

The SH3 domain of Caskin1 binds to lysophosphatidic acid suggesting a direct role for the lipid in intracellular signaling.

Koprivanacz K, Tőke O, Besztercei B, Juhász T, Radnai L, Merő B, Mihály J, Péter M, Balogh G, Vígh L, Buday L, Liliom K.

Cell Signal. 2017 Apr;32:66-75. doi: 10.1016/j.cellsig.2017.01.019. Epub 2017 Jan 16.

PMID:
28104445
13.

The scaffold protein Tks4 is required for the differentiation of mesenchymal stromal cells (MSCs) into adipogenic and osteogenic lineages.

Dülk M, Kudlik G, Fekete A, Ernszt D, Kvell K, Pongrácz JE, Merő BL, Szeder B, Radnai L, Geiszt M, Csécsy DE, Kovács T, Uher F, Lányi Á, Vas V, Buday L.

Sci Rep. 2016 Oct 6;6:34280. doi: 10.1038/srep34280.

14.

Mesenchymal stem cells promote macrophage polarization toward M2b-like cells.

Kudlik G, Hegyi B, Czibula Á, Monostori É, Buday L, Uher F.

Exp Cell Res. 2016 Oct 15;348(1):36-45. doi: 10.1016/j.yexcr.2016.08.022. Epub 2016 Aug 28.

PMID:
27578361
15.

Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomes.

Ádám C, Fekete A, Bőgel G, Németh Z, Tőkési N, Ovádi J, Liliom K, Pesti S, Geiszt M, Buday L.

Cell Commun Signal. 2015 Jul 17;13:33. doi: 10.1186/s12964-015-0108-8.

16.

T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells.

Hem CD, Sundvold-Gjerstad V, Granum S, Koll L, Abrahamsen G, Buday L, Spurkland A.

Cell Commun Signal. 2015 Jul 11;13:31. doi: 10.1186/s12964-015-0109-7.

17.

K153R polymorphism in myostatin gene increases the rate of promyostatin activation by furin.

Szláma G, Trexler M, Buday L, Patthy L.

FEBS Lett. 2015 Jan 30;589(3):295-301. doi: 10.1016/j.febslet.2014.12.011. Epub 2014 Dec 25.

18.

Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation.

Róna G, Borsos M, Ellis JJ, Mehdi AM, Christie M, Környei Z, Neubrandt M, Tóth J, Bozóky Z, Buday L, Madarász E, Bodén M, Kobe B, Vértessy BG.

Cell Cycle. 2014;13(22):3551-64. doi: 10.4161/15384101.2014.960740.

19.

Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.

Róna G, Marfori M, Borsos M, Scheer I, Takács E, Tóth J, Babos F, Magyar A, Erdei A, Bozóky Z, Buday L, Kobe B, Vértessy BG.

Acta Crystallogr D Biol Crystallogr. 2013 Dec;69(Pt 12):2495-505. doi: 10.1107/S0907444913023354. Epub 2013 Nov 19.

PMID:
24311590
20.

Multiple fuzzy interactions in the moonlighting function of thymosin-β4.

Tantos A, Szabo B, Lang A, Varga Z, Tsylonok M, Bokor M, Verebelyi T, Kamasa P, Tompa K, Perczel A, Buday L, Lee SH, Choo Y, Han KH, Tompa P.

Intrinsically Disord Proteins. 2013 Sep 11;1(1):e26204. doi: 10.4161/idp.26204. eCollection 2013 Jan-Dec.

21.

EGF regulates tyrosine phosphorylation and membrane-translocation of the scaffold protein Tks5.

Fekete A, Bőgel G, Pesti S, Péterfi Z, Geiszt M, Buday L.

J Mol Signal. 2013 Aug 7;8:8. doi: 10.1186/1750-2187-8-8. eCollection 2013.

22.

Complex formation of EphB1/Nck/Caskin1 leads to tyrosine phosphorylation and structural changes of the Caskin1 SH3 domain.

Pesti S, Balázs A, Udupa R, Szabó B, Fekete A, Bőgel G, Buday L.

Cell Commun Signal. 2012 Nov 27;10(1):36. doi: 10.1186/1478-811X-10-36.

23.

Frank-ter Haar syndrome protein Tks4 regulates epidermal growth factor-dependent cell migration.

Bögel G, Gujdár A, Geiszt M, Lányi Á, Fekete A, Sipeki S, Downward J, Buday L.

J Biol Chem. 2012 Sep 7;287(37):31321-9. doi: 10.1074/jbc.M111.324897. Epub 2012 Jul 24.

24.

The signaling pathway of Campylobacter jejuni-induced Cdc42 activation: Role of fibronectin, integrin beta1, tyrosine kinases and guanine exchange factor Vav2.

Krause-Gruszczynska M, Boehm M, Rohde M, Tegtmeyer N, Takahashi S, Buday L, Oyarzabal OA, Backert S.

Cell Commun Signal. 2011 Dec 28;9:32. doi: 10.1186/1478-811X-9-32.

25.

The homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreading.

Lányi Á, Baráth M, Péterfi Z, Bogel G, Orient A, Simon T, Petrovszki E, Kis-Tóth K, Sirokmány G, Rajnavölgyi É, Terhorst C, Buday L, Geiszt M.

PLoS One. 2011;6(8):e23653. doi: 10.1371/journal.pone.0023653. Epub 2011 Aug 23.

26.

Accessory proteins in signal transduction: scaffold proteins and beyond.

Buday L, Tompa P.

FEBS J. 2010 Nov;277(21):4347. No abstract available.

27.

Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms.

Radnai L, Rapali P, Hódi Z, Süveges D, Molnár T, Kiss B, Bécsi B, Erdödi F, Buday L, Kardos J, Kovács M, Nyitray L.

J Biol Chem. 2010 Dec 3;285(49):38649-57. doi: 10.1074/jbc.M110.165894. Epub 2010 Oct 2.

28.

Functional classification of scaffold proteins and related molecules.

Buday L, Tompa P.

FEBS J. 2010 Nov;277(21):4348-55. doi: 10.1111/j.1742-4658.2010.07864.x. Epub 2010 Sep 30. Review.

29.

Small-molecule inhibitors of NADPH oxidase 4.

Borbély G, Szabadkai I, Horváth Z, Markó P, Varga Z, Breza N, Baska F, Vántus T, Huszár M, Geiszt M, Hunyady L, Buday L, Orfi L, Kéri G.

J Med Chem. 2010 Sep 23;53(18):6758-62. doi: 10.1021/jm1004368.

PMID:
20731357
30.

The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes.

de Boussac H, Ratajewski M, Sachrajda I, Köblös G, Tordai A, Pulaski L, Buday L, Váradi A, Arányi T.

J Biol Chem. 2010 Jul 23;285(30):22800-8. doi: 10.1074/jbc.M110.105593. Epub 2010 May 12.

31.

Angiotensin II-induced expression of brain-derived neurotrophic factor in human and rat adrenocortical cells.

Szekeres M, Nádasy GL, Turu G, Süpeki K, Szidonya L, Buday L, Chaplin T, Clark AJ, Hunyady L.

Endocrinology. 2010 Apr;151(4):1695-703. doi: 10.1210/en.2009-1060. Epub 2010 Feb 24.

PMID:
20181798
32.

Intrinsic structural disorder confers cellular viability on oncogenic fusion proteins.

Hegyi H, Buday L, Tompa P.

PLoS Comput Biol. 2009 Oct;5(10):e1000552. doi: 10.1371/journal.pcbi.1000552. Epub 2009 Oct 30.

33.

High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1.

Balázs A, Csizmok V, Buday L, Rakács M, Kiss R, Bokor M, Udupa R, Tompa K, Tompa P.

FEBS J. 2009 Jul;276(14):3744-56. doi: 10.1111/j.1742-4658.2009.07090.x. Epub 2009 Jun 11.

34.

Detection of hydrogen peroxide by lactoperoxidase-mediated dityrosine formation.

Donkó A, Orient A, Szabó PT, Németh G, Vántus T, Kéri G, Orfi L, Hunyady L, Buday L, Geiszt M.

Free Radic Res. 2009 May;43(5):440-5. doi: 10.1080/10715760902859069.

PMID:
19340621
35.

Specific tyrosine phosphorylation of focal adhesion kinase mediated by Fer tyrosine kinase in suspended hepatocytes.

Oh MA, Choi S, Lee MJ, Choi MC, Lee SA, Ko W, Cance WG, Oh ES, Buday L, Kim SH, Lee JW.

Biochim Biophys Acta. 2009 May;1793(5):781-91. doi: 10.1016/j.bbamcr.2009.01.015. Epub 2009 Feb 5.

36.

Many faces of Ras activation.

Buday L, Downward J.

Biochim Biophys Acta. 2008 Dec;1786(2):178-87. doi: 10.1016/j.bbcan.2008.05.001. Epub 2008 May 21. Review.

PMID:
18541156
37.

Roles of cortactin in tumor pathogenesis.

Buday L, Downward J.

Biochim Biophys Acta. 2007 Jun;1775(2):263-73. Epub 2007 Jan 9. Review.

PMID:
17292556
38.

Cortactin is required for integrin-mediated cell spreading.

Illés A, Enyedi B, Tamás P, Balázs A, Bogel G, Melinda, Lukács, Buday L.

Immunol Lett. 2006 Apr 15;104(1-2):124-30. Epub 2005 Dec 7.

PMID:
16364453
39.

Differential beta-arrestin binding of AT1 and AT2 angiotensin receptors.

Turu G, Szidonya L, Gáborik Z, Buday L, Spät A, Clark AJ, Hunyady L.

FEBS Lett. 2006 Jan 9;580(1):41-5. Epub 2005 Dec 6.

40.

Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners.

Várnai P, Bondeva T, Tamás P, Tóth B, Buday L, Hunyady L, Balla T.

J Cell Sci. 2005 Oct 15;118(Pt 20):4879-88.

41.

Inducible phosphorylation of cortactin is not necessary for cortactin-mediated actin polymerisation.

Illés A, Enyedi B, Tamás P, Balázs A, Bogel G, Buday L.

Cell Signal. 2006 Jun;18(6):830-40. Epub 2005 Aug 16.

PMID:
16109479
42.

Structural disorder throws new light on moonlighting.

Tompa P, Szász C, Buday L.

Trends Biochem Sci. 2005 Sep;30(9):484-9. Review.

PMID:
16054818
43.

Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib).

Elkind NB, Szentpétery Z, Apáti A, Ozvegy-Laczka C, Várady G, Ujhelly O, Szabó K, Homolya L, Váradi A, Buday L, Kéri G, Német K, Sarkadi B.

Cancer Res. 2005 Mar 1;65(5):1770-7.

44.
46.

Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac.

Tamás P, Solti Z, Bauer P, Illés A, Sipeki S, Bauer A, Faragó A, Downward J, Buday L.

J Biol Chem. 2003 Feb 14;278(7):5163-71. Epub 2002 Nov 25.

47.

The Nck family of adapter proteins: regulators of actin cytoskeleton.

Buday L, Wunderlich L, Tamás P.

Cell Signal. 2002 Sep;14(9):723-31. Review.

PMID:
12034353
48.

Membrane-targeting is critical for the phosphorylation of Vav2 by activated EGF receptor.

Tamás P, Solti Z, Buday L.

Cell Signal. 2001 Jul;13(7):475-81.

PMID:
11516622
49.

Phosphatidylinositol 3-kinase contributes to Erk1/Erk2 MAP kinase activation associated with hepatocyte growth factor-induced cell scattering.

Sipeki S, Bander E, Buday L, Farkas G, Bácsy E, Ways DK, Faragó A.

Cell Signal. 1999 Dec;11(12):885-90.

PMID:
10659996
50.

Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins.

Buday L.

Biochim Biophys Acta. 1999 Jul 6;1422(2):187-204. Review.

PMID:
10393272

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