Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 93

1.

Naphthalene cytotoxicity in microsomal epoxide hydrolase deficient mice.

Carratt SA, Morin D, Buckpitt AR, Edwards PC, Van Winkle LS.

Toxicol Lett. 2016 Mar 30;246:35-41. doi: 10.1016/j.toxlet.2016.01.019. Epub 2016 Feb 1.

2.

Simultaneous quantification of multiple urinary naphthalene metabolites by liquid chromatography tandem mass spectrometry.

Ayala DC, Morin D, Buckpitt AR.

PLoS One. 2015 Apr 8;10(4):e0121937. doi: 10.1371/journal.pone.0121937. eCollection 2015.

3.

Metabolic activation of the antibacterial agent triclocarban by cytochrome P450 1A1 yielding glutathione adducts.

Schebb NH, Muvvala JB, Morin D, Buckpitt AR, Hammock BD, Rice RH.

Drug Metab Dispos. 2014 Jul;42(7):1098-102. doi: 10.1124/dmd.114.058206. Epub 2014 Apr 14.

4.

Sex differences in the acute nasal antioxidant/antielectrophilic response of the rat to inhaled naphthalene.

Cichocki JA, Smith GJ, Mendoza R, Buckpitt AR, Van Winkle LS, Morris JB.

Toxicol Sci. 2014 May;139(1):234-44. doi: 10.1093/toxsci/kfu031. Epub 2014 Feb 22.

PMID:
24563378
5.

Characterization of model peptide adducts with reactive metabolites of naphthalene by mass spectrometry.

Pham NT, Jewell WT, Morin D, Jones AD, Buckpitt AR.

PLoS One. 2012;7(8):e42053. doi: 10.1371/journal.pone.0042053. Epub 2012 Aug 3.

6.

Lung effects of inhaled corticosteroids in a rhesus monkey model of childhood asthma.

Plopper CG, Joad JP, Miller LA, Schelegle ES, Fanucchi MV, Van Winkle LS, Tyler NK, Avdalovic MV, Evans MJ, Lasley WL, Buckpitt AR, Pinkerton KE, Tarkington BK, Davis S, Nishio SJ, Gershwin LJ, Wu R, Hyde DM.

Clin Exp Allergy. 2012 Jul;42(7):1104-18. doi: 10.1111/j.1365-2222.2012.04005.x.

7.

Analysis of naphthalene adduct binding sites in model proteins by tandem mass spectrometry.

Pham NT, Jewell WT, Morin D, Buckpitt AR.

Chem Biol Interact. 2012 Aug 30;199(2):120-8. doi: 10.1016/j.cbi.2012.05.009. Epub 2012 May 31.

8.

Free flow electrophoresis separation and AMS quantitation of C-naphthalene-protein adducts.

Buchholz BA, Haack KW, Sporty JL, Buckpitt AR, Morin D.

Nucl Instrum Methods Phys Res B. 2010 Apr 1;268(7-8):1324-1327.

9.

Protein thiol oxidation in murine airway epithelial cells in response to naphthalene or diethyl maleate.

Spiess PC, Morin D, Williams CR, Buckpitt AR.

Am J Respir Cell Mol Biol. 2010 Sep;43(3):316-25. doi: 10.1165/rcmb.2009-0135OC. Epub 2009 Oct 20.

10.

Upper respiratory tract uptake of naphthalene.

Morris JB, Buckpitt AR.

Toxicol Sci. 2009 Oct;111(2):383-91. doi: 10.1093/toxsci/kfp138. Epub 2009 Jul 31.

PMID:
19648534
11.

Equine cytochrome P450 2C92: cDNA cloning, expression and initial characterization.

DiMaio Knych HK, DeStefano Shields C, Buckpitt AR, Stanley SD.

Arch Biochem Biophys. 2009 May 1;485(1):49-55. doi: 10.1016/j.abb.2009.02.009. Epub 2009 Feb 24.

PMID:
19245785
12.

Measurement of protein sulfhydryls in response to cellular oxidative stress using gel electrophoresis and multiplexed fluorescent imaging analysis.

Spiess PC, Morin D, Jewell WT, Buckpitt AR.

Chem Res Toxicol. 2008 May;21(5):1074-85. doi: 10.1021/tx8000708. Epub 2008 Apr 17.

13.

Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase.

Morisseau C, Newman JW, Wheelock CE, Hill Iii T, Morin D, Buckpitt AR, Hammock BD.

Chem Res Toxicol. 2008 Apr;21(4):951-7. doi: 10.1021/tx700446u. Epub 2008 Mar 25.

PMID:
18363382
14.

Asthma/allergic airways disease: does postnatal exposure to environmental toxicants promote airway pathobiology?

Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM.

Toxicol Pathol. 2007 Jan;35(1):97-110.

PMID:
17325978
15.

Identification of proteins adducted by reactive metabolites of naphthalene and 1-nitronaphthalene in dissected airways of rhesus macaques.

Lin CY, Boland BC, Lee YJ, Salemi MR, Morin D, Miller LA, Plopper CG, Buckpitt AR.

Proteomics. 2006 Feb;6(3):972-82.

PMID:
16453347
16.

Use of a fluorescent internal protein standard to achieve quantitative two-dimensional gel electrophoresis.

Wheelock AM, Morin D, Bartosiewicz M, Buckpitt AR.

Proteomics. 2006 Mar;6(5):1385-98.

PMID:
16429456
17.

Software-induced variance in two-dimensional gel electrophoresis image analysis.

Wheelock AM, Buckpitt AR.

Electrophoresis. 2005 Dec;26(23):4508-20.

PMID:
16315176
18.

Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells.

Schoenfeld RA, Napoli E, Wong A, Zhan S, Reutenauer L, Morin D, Buckpitt AR, Taroni F, Lonnerdal B, Ristow M, Puccio H, Cortopassi GA.

Hum Mol Genet. 2005 Dec 15;14(24):3787-99. Epub 2005 Oct 20.

PMID:
16239244
19.

Characterization of a structurally intact in situ lung model and comparison of naphthalene protein adducts generated in this model vs lung microsomes.

Lin CY, Isbell MA, Morin D, Boland BC, Salemi MR, Jewell WT, Weir AJ, Fanucchi MV, Baker GL, Plopper CG, Buckpitt AR.

Chem Res Toxicol. 2005 May;18(5):802-13.

PMID:
15892573
20.

In vivo effects of ozone exposure on protein adduct formation by 1-nitronaphthalene in rat lung.

Wheelock AM, Boland BC, Isbell M, Morin D, Wegesser TC, Plopper CG, Buckpitt AR.

Am J Respir Cell Mol Biol. 2005 Aug;33(2):130-7. Epub 2005 Apr 21.

21.
22.

Bioactivation of the pulmonary toxicants naphthalene and 1-nitronaphthalene by rat CYP2F4.

Baldwin RM, Shultz MA, Buckpitt AR.

J Pharmacol Exp Ther. 2005 Feb;312(2):857-65. Epub 2004 Oct 27.

PMID:
15509722
23.

Glutathione depletion is a major determinant of inhaled naphthalene respiratory toxicity and naphthalene metabolism in mice.

Phimister AJ, Lee MG, Morin D, Buckpitt AR, Plopper CG.

Toxicol Sci. 2004 Nov;82(1):268-78. Epub 2004 Aug 19.

PMID:
15319489
24.

Comparison of pulmonary/nasal CYP2F expression levels in rodents and rhesus macaque.

Baldwin RM, Jewell WT, Fanucchi MV, Plopper CG, Buckpitt AR.

J Pharmacol Exp Ther. 2004 Apr;309(1):127-36. Epub 2004 Jan 14.

PMID:
14724224
25.

Assessing gene expression in lung subcompartments utilizing in situ RNA preservation.

Baker GL, Shultz MA, Fanucchi MV, Morin DM, Buckpitt AR, Plopper CG.

Toxicol Sci. 2004 Jan;77(1):135-41. Epub 2003 Nov 4.

PMID:
14600286
26.

Isolation of rodent airway epithelial cell proteins facilitates in vivo proteomics studies of lung toxicity.

Wheelock AM, Zhang L, Tran MU, Morin D, Penn S, Buckpitt AR, Plopper CG.

Am J Physiol Lung Cell Mol Physiol. 2004 Feb;286(2):L399-410. Epub 2003 Oct 31.

27.

Gene expression analysis in response to lung toxicants: I. Sequencing and microarray development.

Shultz MA, Zhang L, Gu YZ, Baker GL, Fannuchi MV, Padua AM, Gurske WA, Morin D, Penn SG, Jovanovich SB, Plopper CG, Buckpitt AR.

Am J Respir Cell Mol Biol. 2004 Mar;30(3):296-310. Epub 2003 Aug 28.

PMID:
12947022
28.

Measurement of glutathione conjugates.

Shultz MA, Morin D, Chan KW, Buckpitt AR.

Curr Protoc Toxicol. 2003;Chapter 6:Unit6.8. doi: 10.1002/0471140856.tx0608s14.

PMID:
23045094
29.

Pharmacokinetics and metabolism of a novel antifibrotic drug pirfenidone, in mice following intravenous administration.

Giri SN, Wang Q, Xie Y, Lango J, Morin D, Margolin SB, Buckpitt AR.

Biopharm Drug Dispos. 2002 Jul;23(5):203-11.

PMID:
12116052
30.

Induction of tolerance to naphthalene in Clara cells is dependent on a stable phenotypic adaptation favoring maintenance of the glutathione pool.

West JA, Williams KJ, Toskala E, Nishio SJ, Fleschner CA, Forman HJ, Buckpitt AR, Plopper CG.

Am J Pathol. 2002 Mar;160(3):1115-27. Erratum in: Am J Pathol. 2003 Aug;163(2):803.

31.

Inhaled naphthalene causes dose dependent Clara cell cytotoxicity in mice but not in rats.

West JA, Pakehham G, Morin D, Fleschner CA, Buckpitt AR, Plopper CG.

Toxicol Appl Pharmacol. 2001 Jun 1;173(2):114-9.

PMID:
11384213
32.

Early events in naphthalene-induced acute Clara cell toxicity. II. Comparison of glutathione depletion and histopathology by airway location.

Plopper CG, Van Winkle LS, Fanucchi MV, Malburg SR, Nishio SJ, Chang A, Buckpitt AR.

Am J Respir Cell Mol Biol. 2001 Mar;24(3):272-81.

PMID:
11245626
33.

Allergic asthma induced in rhesus monkeys by house dust mite (Dermatophagoides farinae).

Schelegle ES, Gershwin LJ, Miller LA, Fanucchi MV, Van Winkle LS, Gerriets JP, Walby WF, Omlor AM, Buckpitt AR, Tarkington BK, Wong VJ, Joad JP, Pinkerton KB, Wu R, Evans MJ, Hyde DM, Plopper CG.

Am J Pathol. 2001 Jan;158(1):333-41.

34.

Long-term exposure to ozone increases acute pulmonary centriacinar injury by 1-nitronaphthalene: I. Region-specific enzyme activity.

Paige RC, Royce FH, Plopper CG, Buckpitt AR.

J Pharmacol Exp Ther. 2000 Dec;295(3):934-41.

PMID:
11082426
35.

Development of phase II xenobiotic metabolizing enzymes in differentiating murine clara cells.

Fanucchi MV, Buckpitt AR, Murphy ME, Storms DH, Hammock BD, Plopper CG.

Toxicol Appl Pharmacol. 2000 Nov 1;168(3):253-67.

PMID:
11042098
36.
37.

Heterogeneity of clara cell glutathione. A possible basis for differences in cellular responses to pulmonary cytotoxicants.

West JA, Chichester CH, Buckpitt AR, Tyler NK, Brennan P, Helton C, Plopper CG.

Am J Respir Cell Mol Biol. 2000 Jul;23(1):27-36.

PMID:
10873150
38.

Species differences in the regio- and stereoselectivity of 1-nitronaphthalene metabolism.

Watt KC, Buckpitt AR.

Drug Metab Dispos. 2000 Apr;28(4):376-8.

PMID:
10725302
39.

Hepatic and pulmonary enzyme activities in horses.

Lakritz J, Winder BS, Noorouz-Zadeh J, Huang TL, Buckpitt AR, Hammock BD, Plopper CG.

Am J Vet Res. 2000 Feb;61(2):152-7.

PMID:
10685686
41.

Role of murine cytochrome P-450 2F2 in metabolic activation of naphthalene and metabolism of other xenobiotics.

Shultz MA, Choudary PV, Buckpitt AR.

J Pharmacol Exp Ther. 1999 Jul;290(1):281-8.

PMID:
10381788
42.

Relationship of inhaled ozone concentration to acute tracheobronchial epithelial injury, site-specific ozone dose, and glutathione depletion in rhesus monkeys.

Plopper CG, Hatch GE, Wong V, Duan X, Weir AJ, Tarkington BK, Devlin RB, Becker S, Buckpitt AR.

Am J Respir Cell Mol Biol. 1998 Sep;19(3):387-99.

PMID:
9730866
43.

Site-selective differences in cytochrome P450 isoform activities. Comparison of expression in rat and rhesus monkey lung and induction in rats.

Lee C, Watt KC, Chang AM, Plopper CG, Buckpitt AR, Pinkerton KE.

Drug Metab Dispos. 1998 May;26(5):396-400.

PMID:
9571220
44.

Cytochrome P450 2E1 in rat tracheobronchial airways: response to ozone exposure.

Watt KC, Plopper CG, Weir AJ, Tarkington B, Buckpitt AR.

Toxicol Appl Pharmacol. 1998 Apr;149(2):195-202.

PMID:
9571988
45.

Pulmonary cytochrome P450 monooxygenase and Clara cell differentiation in mice.

Fanucchi MV, Murphy ME, Buckpitt AR, Philpot RM, Plopper CG.

Am J Respir Cell Mol Biol. 1997 Sep;17(3):302-14.

PMID:
9308917
47.

Naphthalene cytotoxicity of differentiating Clara cells in neonatal mice.

Fanucchi MV, Buckpitt AR, Murphy ME, Plopper CG.

Toxicol Appl Pharmacol. 1997 May;144(1):96-104.

PMID:
9169074
49.

Characterisation of the toxic metabolite(s) of naphthalene.

Wilson AS, Davis CD, Williams DP, Buckpitt AR, Pirmohamed M, Park BK.

Toxicology. 1996 Dec 18;114(3):233-42. Erratum in: Toxicology 1997 Jun 6;120(1):75.

PMID:
8980712
50.

Maintenance of differentiated murine Clara cells in microdissected airway cultures.

Van Winkle LS, Buckpitt AR, Plopper CG.

Am J Respir Cell Mol Biol. 1996 Jun;14(6):586-98.

PMID:
8652187

Supplemental Content

Loading ...
Support Center