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Items: 1 to 50 of 117

1.

Multiparameter Analysis Identifies Heterogeneity in Knee Osteoarthritis Synovial Responses.

Labinsky H, Panipinto PM, Ly KA, Khuat DK, Madarampalli B, Mahajan V, Clabeaux J, MacDonald K, Verdin PJ, Buckner JH, Noss EH.

Arthritis Rheumatol. 2019 Nov 8. doi: 10.1002/art.41161. [Epub ahead of print]

PMID:
31702112
2.

Corrigendum: Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis.

Dam EM, Maier AC, Hocking AM, Carlin J, Ng B, Buckner JH.

Front Immunol. 2019 May 16;10:1122. doi: 10.3389/fimmu.2019.01122. eCollection 2019.

3.

Coordinated Induction of Antimicrobial Response Factors in Systemic Lupus Erythematosus.

Ayyappan P, Harms RZ, Buckner JH, Sarvetnick NE.

Front Immunol. 2019 Apr 4;10:658. doi: 10.3389/fimmu.2019.00658. eCollection 2019.

4.

Anticyclic Citrullinated Peptide Antibodies 3.1 and Anti-CCP-IgA Are Associated with Increasing Age in Individuals Without Rheumatoid Arthritis.

Berens HM, Polinski KJ, Mikuls TR, Khatter S, August J, Visser A, Mahler M, Weisman MH, O'Dell JR, Keating RM, Buckner JH, Gregersen PK, Norris JM, Holers VM, Deane KD, Demoruelle MK.

J Rheumatol. 2019 Dec;46(12):1556-1559. doi: 10.3899/jrheum.180897. Epub 2019 Apr 15.

PMID:
30988128
5.

Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression.

Habib T, Long SA, Samuels PL, Brahmandam A, Tatum M, Funk A, Hocking AM, Cerosaletti K, Mason MT, Whalen E, Rawlings DJ, Greenbaum C, Buckner JH; Type 1 Diabetes TrialNet Study Group.

Diabetes. 2019 Jun;68(6):1240-1250. doi: 10.2337/db18-1081. Epub 2019 Mar 20.

6.

Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.

Johnson MB, Cerosaletti K, Flanagan SE, Buckner JH.

Curr Diab Rep. 2019 Mar 19;19(5):20. doi: 10.1007/s11892-019-1141-6. Review.

7.

Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity.

Stathopoulos P, Chastre A, Waters P, Irani S, Fichtner ML, Benotti ES, Guthridge JM, Seifert J, Nowak RJ, Buckner JH, Holers VM, James JA, Hafler DA, O'Connor KC.

J Immunol. 2019 Apr 15;202(8):2210-2219. doi: 10.4049/jimmunol.1801295. Epub 2019 Mar 1.

8.

The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.

Gorman JA, Hundhausen C, Kinsman M, Arkatkar T, Allenspach EJ, Clough C, West SE, Thomas K, Eken A, Khim S, Hale M, Oukka M, Jackson SW, Cerosaletti K, Buckner JH, Rawlings DJ.

Front Immunol. 2019 Jan 25;10:44. doi: 10.3389/fimmu.2019.00044. eCollection 2019.

9.

Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.

Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E.

J Immunol. 2019 Mar 1;202(5):1373-1382. doi: 10.4049/jimmunol.1801425. Epub 2019 Jan 25.

PMID:
30683697
10.

Citrullinated Aggrecan Epitopes as Targets of Autoreactive CD4+ T Cells in Patients With Rheumatoid Arthritis.

Rims C, Uchtenhagen H, Kaplan MJ, Carmona-Rivera C, Carlucci P, Mikecz K, Markovics A, Carlin J, Buckner JH, James EA.

Arthritis Rheumatol. 2019 Apr;71(4):518-528. doi: 10.1002/art.40768. Epub 2019 Mar 8. Erratum in: Arthritis Rheumatol. 2019 Jun;71(6):907.

PMID:
30390384
11.

IL-6: a cytokine at the crossroads of autoimmunity.

Jones BE, Maerz MD, Buckner JH.

Curr Opin Immunol. 2018 Dec;55:9-14. doi: 10.1016/j.coi.2018.09.002. Epub 2018 Sep 21. Review.

12.

Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis.

Dam EM, Maier AC, Hocking AM, Carlin J, Ng B, Buckner JH.

Front Immunol. 2018 Sep 5;9:1978. doi: 10.3389/fimmu.2018.01978. eCollection 2018. Erratum in: Front Immunol. 2019 May 16;10:1122.

13.

Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction.

Holers VM, Demoruelle MK, Kuhn KA, Buckner JH, Robinson WH, Okamoto Y, Norris JM, Deane KD.

Nat Rev Rheumatol. 2018 Sep;14(9):542-557. doi: 10.1038/s41584-018-0070-0. Review.

14.

Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.

Pieper J, Dubnovitsky A, Gerstner C, James EA, Rieck M, Kozhukh G, Tandre K, Pellegrino S, Gebe JA, Rönnblom L, Sandalova T, Kwok WW, Klareskog L, Buckner JH, Achour A, Malmström V.

J Autoimmun. 2018 Aug;92:47-56. doi: 10.1016/j.jaut.2018.04.004. Epub 2018 May 28.

15.

Circulating integrin alpha4/beta7+ lymphocytes targeted by vedolizumab have a pro-inflammatory phenotype.

Lord JD, Long SA, Shows DM, Thorpe J, Schwedhelm K, Chen J, Kita M, Buckner JH.

Clin Immunol. 2018 Aug;193:24-32. doi: 10.1016/j.clim.2018.05.006. Epub 2018 May 26.

16.

Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".

Carmona-Rivera C, Bicker KL, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ.

Sci Immunol. 2018 Mar 30;3(21). pii: eaar3701. doi: 10.1126/sciimmunol.aar3701.

17.

Stacking the Deck: Studies of Patients with Multiple Autoimmune Diseases Propelled Our Understanding of Type 1 Diabetes as an Autoimmune Disease.

Buckner JH, Greenbaum CJ.

J Immunol. 2017 Nov 1;199(9):3011-3013. doi: 10.4049/jimmunol.1701299. No abstract available.

18.

Corrigendum: Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C, Dubnovitsky A, Sandin C, Kozhukh G, Uchtenhagen H, James EA, Rönnelid J, Ytterberg AJ, Pieper J, Reed E, Tandre K, Rieck M, Zubarev RA, Rönnblom L, Sandalova T, Buckner JH, Achour A, Malmström V.

Front Immunol. 2017 Oct 4;8:1236. doi: 10.3389/fimmu.2017.01236. eCollection 2017.

19.

S1P1 deletion differentially affects TH17 and Regulatory T cells.

Eken A, Duhen R, Singh AK, Fry M, Buckner JH, Kita M, Bettelli E, Oukka M.

Sci Rep. 2017 Oct 10;7(1):12905. doi: 10.1038/s41598-017-13376-2.

20.

Erratum to: Understanding and preventing type 1 diabetes through the unique working model of TrialNet.

Battaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark Å, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M.

Diabetologia. 2017 Dec;60(12):2540. doi: 10.1007/s00125-017-4446-5. No abstract available.

21.

B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity.

Arkatkar T, Du SW, Jacobs HM, Dam EM, Hou B, Buckner JH, Rawlings DJ, Jackson SW.

J Exp Med. 2017 Nov 6;214(11):3207-3217. doi: 10.1084/jem.20170580. Epub 2017 Sep 12.

22.

The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.

Metzler G, Dai X, Thouvenel CD, Khim S, Habib T, Buckner JH, Rawlings DJ.

J Immunol. 2017 Oct 1;199(7):2249-2260. doi: 10.4049/jimmunol.1700601. Epub 2017 Aug 11.

23.

Understanding and preventing type 1 diabetes through the unique working model of TrialNet.

Battaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark Å, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M.

Diabetologia. 2017 Nov;60(11):2139-2147. doi: 10.1007/s00125-017-4384-2. Epub 2017 Aug 2. Review. Erratum in: Diabetologia. 2017 Sep 26;:.

24.

Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.

Carmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James E, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson P, Buckner JH, Robinson WH, Fox DA, Kaplan MJ.

Sci Immunol. 2017 Apr;2(10). pii: eaag3358. doi: 10.1126/sciimmunol.aag3358. Epub 2017 Apr 14.

25.

A novel and rapid method to quantify Treg mediated suppression of CD4 T cells.

Long AE, Tatum M, Mikacenic C, Buckner JH.

J Immunol Methods. 2017 Oct;449:15-22. doi: 10.1016/j.jim.2017.06.009. Epub 2017 Jun 22.

26.

The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.

Gorman JA, Hundhausen C, Errett JS, Stone AE, Allenspach EJ, Ge Y, Arkatkar T, Clough C, Dai X, Khim S, Pestal K, Liggitt D, Cerosaletti K, Stetson DB, James RG, Oukka M, Concannon P, Gale M Jr, Buckner JH, Rawlings DJ.

Nat Immunol. 2017 Jul;18(7):744-752. doi: 10.1038/ni.3766. Epub 2017 May 29.

27.

Impact of Age and Antibody Type on Progression From Single to Multiple Autoantibodies in Type 1 Diabetes Relatives.

Bosi E, Boulware DC, Becker DJ, Buckner JH, Geyer S, Gottlieb PA, Henderson C, Kinderman A, Sosenko JM, Steck AK, Bingley PJ; Type 1 Diabetes TrialNet Study Group.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2881-2886. doi: 10.1210/jc.2017-00569.

28.

Native-Like and Denatured Cytochrome c Ions Yield Cation-to-Anion Proton Transfer Reaction Products with Similar Collision Cross-Sections.

Laszlo KJ, Buckner JH, Munger EB, Bush MF.

J Am Soc Mass Spectrom. 2017 Jul;28(7):1382-1391. doi: 10.1007/s13361-017-1620-4. Epub 2017 Feb 21.

29.

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C, Dubnovitsky A, Sandin C, Kozhukh G, Uchtenhagen H, James EA, Rönnelid J, Ytterberg AJ, Pieper J, Reed E, Tandre K, Rieck M, Zubarev RA, Rönnblom L, Sandalova T, Buckner JH, Achour A, Malmström V.

Front Immunol. 2016 Nov 14;7:494. eCollection 2016. Erratum in: Front Immunol. 2017 Oct 04;8:1236.

30.

Editorial overview: Autoimmunity.

Haskins K, Buckner JH.

Curr Opin Immunol. 2016 Dec;43:v-vii. doi: 10.1016/j.coi.2016.10.002. Epub 2016 Nov 10. No abstract available.

PMID:
27839940
31.

The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans.

Dam EM, Habib T, Chen J, Funk A, Glukhova V, Davis-Pickett M, Wei S, James R, Buckner JH, Cerosaletti K.

Clin Immunol. 2016 Dec;173:171-180. doi: 10.1016/j.clim.2016.10.018. Epub 2016 Nov 2.

32.

Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression.

Hundhausen C, Roth A, Whalen E, Chen J, Schneider A, Long SA, Wei S, Rawlings R, Kinsman M, Evanko SP, Wight TN, Greenbaum CJ, Cerosaletti K, Buckner JH.

Sci Transl Med. 2016 Sep 14;8(356):356ra119. doi: 10.1126/scitranslmed.aad9943.

33.

Distinct T cell signatures define subsets of patients with multiple sclerosis.

Johnson MC, Pierson ER, Spieker AJ, Nielsen AS, Posso S, Kita M, Buckner JH, Goverman JM.

Neurol Neuroimmunol Neuroinflamm. 2016 Aug 23;3(5):e278. doi: 10.1212/NXI.0000000000000278. eCollection 2016 Oct.

34.

Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining.

Uchtenhagen H, Rims C, Blahnik G, Chow IT, Kwok WW, Buckner JH, James EA.

Nat Commun. 2016 Aug 30;7:12614. doi: 10.1038/ncomms12614.

35.

Omega-3 fatty acids are associated with a lower prevalence of autoantibodies in shared epitope-positive subjects at risk for rheumatoid arthritis.

Gan RW, Demoruelle MK, Deane KD, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Fingerlin TE, Zerbe GO, Clare-Salzler MJ, Holers VM, Norris JM.

Ann Rheum Dis. 2017 Jan;76(1):147-152. doi: 10.1136/annrheumdis-2016-209154. Epub 2016 May 17.

36.

Correction: CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis.

Roan F, Stoklasek TA, Whalen E, Molitor JA, Bluestone JA, Buckner JH, Ziegler SF.

J Immunol. 2016 May 1;196(9):3966. doi: 10.4049/jimmunol.1600364. No abstract available.

37.

B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6.

Jackson SW, Jacobs HM, Arkatkar T, Dam EM, Scharping NE, Kolhatkar NS, Hou B, Buckner JH, Rawlings DJ.

J Exp Med. 2016 May 2;213(5):733-50. doi: 10.1084/jem.20151724. Epub 2016 Apr 11.

38.

Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes.

Buckner JH, Nepom GT.

J Autoimmun. 2016 Jul;71:44-50. doi: 10.1016/j.jaut.2016.02.009. Epub 2016 Mar 3. Review.

39.

Associations of Smoking and Age With Inflammatory Joint Signs Among Unaffected First-Degree Relatives of Rheumatoid Arthritis Patients: Results From Studies of the Etiology of Rheumatoid Arthritis.

Sparks JA, Chang SC, Deane KD, Gan RW, Kristen Demoruelle M, Feser ML, Moss L, Buckner JH, Keating RM, Costenbader KH, Gregersen PK, Weisman MH, Mikuls TR, O'Dell JR, Michael Holers V, Norris JM, Karlson EW.

Arthritis Rheumatol. 2016 Aug;68(8):1828-38. doi: 10.1002/art.39630.

40.

CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis.

Roan F, Stoklasek TA, Whalen E, Molitor JA, Bluestone JA, Buckner JH, Ziegler SF.

J Immunol. 2016 Mar 1;196(5):2051-2062. doi: 10.4049/jimmunol.1501491. Epub 2016 Jan 29. Erratum in: J Immunol. 2016 May 1;196(9):3966.

41.

Negative regulation of TLR signaling in myeloid cells--implications for autoimmune diseases.

Hamerman JA, Pottle J, Ni M, He Y, Zhang ZY, Buckner JH.

Immunol Rev. 2016 Jan;269(1):212-27. doi: 10.1111/imr.12381. Review.

42.

Targeted Deep Sequencing in Multiple-Affected Sibships of European Ancestry Identifies Rare Deleterious Variants in PTPN22 That Confer Risk for Type 1 Diabetes.

Ge Y, Onengut-Gumuscu S, Quinlan AR, Mackey AJ, Wright JA, Buckner JH, Habib T, Rich SS, Concannon P.

Diabetes. 2016 Mar;65(3):794-802. doi: 10.2337/db15-0322. Epub 2015 Dec 2.

43.

Type 1 diabetes immunotherapy using polyclonal regulatory T cells.

Bluestone JA, Buckner JH, Fitch M, Gitelman SE, Gupta S, Hellerstein MK, Herold KC, Lares A, Lee MR, Li K, Liu W, Long SA, Masiello LM, Nguyen V, Putnam AL, Rieck M, Sayre PH, Tang Q.

Sci Transl Med. 2015 Nov 25;7(315):315ra189. doi: 10.1126/scitranslmed.aad4134.

44.

Lower omega-3 fatty acids are associated with the presence of anti-cyclic citrullinated peptide autoantibodies in a population at risk for future rheumatoid arthritis: a nested case-control study.

Gan RW, Young KA, Zerbe GO, Demoruelle MK, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Clare-Salzler MJ, Deane KD, Holers VM, Norris JM.

Rheumatology (Oxford). 2016 Feb;55(2):367-76. doi: 10.1093/rheumatology/kev266. Epub 2015 Sep 13.

45.

Retraction. Novel APC-like properties of human NK cells directly regulate T cell activation.

Hanna J, Gonen-Gross T, Fitchett J, Rowe T, Daniels M, Arnon TI, Gazit R, Joseph A, Schjetne KW, Steinle A, Porgador A, Mevorach D, Goldman-Wohl D, Yagel S, LaBarre MJ, Buckner JH, Mandelboim O.

J Clin Invest. 2015 Apr;125(4):1763. doi: 10.1172/JCI81527. Epub 2015 Apr 1. No abstract available.

46.

The role of PTPN22 risk variant in the development of autoimmunity: finding common ground between mouse and human.

Rawlings DJ, Dai X, Buckner JH.

J Immunol. 2015 Apr 1;194(7):2977-84. doi: 10.4049/jimmunol.1403034. Review.

47.

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients.

Rosenzwajg M, Churlaud G, Mallone R, Six A, Dérian N, Chaara W, Lorenzon R, Long SA, Buckner JH, Afonso G, Pham HP, Hartemann A, Yu A, Pugliese A, Malek TR, Klatzmann D.

J Autoimmun. 2015 Apr;58:48-58. doi: 10.1016/j.jaut.2015.01.001. Epub 2015 Jan 26.

48.

Cutting edge: Genetic variation in TLR1 is associated with Pam3CSK4-induced effector T cell resistance to regulatory T cell suppression.

Mikacenic C, Schneider A, Radella F, Buckner JH, Wurfel MM.

J Immunol. 2014 Dec 15;193(12):5786-90. doi: 10.4049/jimmunol.1401185. Epub 2014 Nov 5.

49.

Citrulline-specific Th1 cells are increased in rheumatoid arthritis and their frequency is influenced by disease duration and therapy.

James EA, Rieck M, Pieper J, Gebe JA, Yue BB, Tatum M, Peda M, Sandin C, Klareskog L, Malmström V, Buckner JH.

Arthritis Rheumatol. 2014 Jul;66(7):1712-22. doi: 10.1002/art.38637.

50.

Low HERV-K(C4) copy number is associated with type 1 diabetes.

Mason MJ, Speake C, Gersuk VH, Nguyen QA, O'Brien KK, Odegard JM, Buckner JH, Greenbaum CJ, Chaussabel D, Nepom GT.

Diabetes. 2014 May;63(5):1789-95. doi: 10.2337/db13-1382. Epub 2014 Jan 15.

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