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Items: 34

1.

Elucidating the Mechanism of Absorption of Fast-Acting Insulin Aspart: The Role of Niacinamide.

Kildegaard J, Buckley ST, Nielsen RH, Povlsen GK, Seested T, Ribel U, Olsen HB, Ludvigsen S, Jeppesen CB, Refsgaard HHF, Bendtsen KM, Kristensen NR, Hostrup S, Sturis J.

Pharm Res. 2019 Feb 11;36(3):49. doi: 10.1007/s11095-019-2578-7.

2.

An ingestible self-orienting system for oral delivery of macromolecules.

Abramson A, Caffarel-Salvador E, Khang M, Dellal D, Silverstein D, Gao Y, Frederiksen MR, Vegge A, Hubálek F, Water JJ, Friderichsen AV, Fels J, Kirk RK, Cleveland C, Collins J, Tamang S, Hayward A, Landh T, Buckley ST, Roxhed N, Rahbek U, Langer R, Traverso G.

Science. 2019 Feb 8;363(6427):611-615. doi: 10.1126/science.aau2277.

PMID:
30733413
3.

Overcoming Poor Tabletability of Bulky Absorption Enhancers by Spray Drying Technology.

Fan W, Wang A, Wu Y, Water JJ, Buckley ST, Hovgaard L, Yang M, Gan Y.

J Pharm Sci. 2019 Jun;108(6):2128-2135. doi: 10.1016/j.xphs.2019.01.025. Epub 2019 Feb 2.

PMID:
30721708
4.

Transcellular stomach absorption of a derivatized glucagon-like peptide-1 receptor agonist.

Buckley ST, Bækdal TA, Vegge A, Maarbjerg SJ, Pyke C, Ahnfelt-Rønne J, Madsen KG, Schéele SG, Alanentalo T, Kirk RK, Pedersen BL, Skyggebjerg RB, Benie AJ, Strauss HM, Wahlund PO, Bjerregaard S, Farkas E, Fekete C, Søndergaard FL, Borregaard J, Hartoft-Nielsen ML, Knudsen LB.

Sci Transl Med. 2018 Nov 14;10(467). pii: eaar7047. doi: 10.1126/scitranslmed.aar7047.

PMID:
30429357
5.

The insulin receptor is expressed and functional in cultured blood-brain barrier endothelial cells but does not mediate insulin entry from blood to brain.

Hersom M, Helms HC, Schmalz C, Pedersen TÅ, Buckley ST, Brodin B.

Am J Physiol Endocrinol Metab. 2018 Oct 1;315(4):E531-E542. doi: 10.1152/ajpendo.00350.2016. Epub 2018 Mar 27.

PMID:
29584446
6.

Dodecylmaltoside Modulates Bicellular Tight Junction Contacts To Promote Enhanced Permeability.

Gradauer K, Iida M, Watari A, Kataoka M, Yamashita S, Kondoh M, Buckley ST.

Mol Pharm. 2017 Dec 4;14(12):4734-4740. doi: 10.1021/acs.molpharmaceut.7b00297. Epub 2017 Oct 27.

PMID:
28985076
7.

Chemically modified peptides and proteins - critical considerations for oral delivery.

Buckley ST, Hubálek F, Rahbek UL.

Tissue Barriers. 2016 Mar 3;4(2):e1156805. doi: 10.1080/21688370.2016.1156805. eCollection 2016 Apr-Jun. Review.

8.

In silico modelling of permeation enhancement potency in Caco-2 monolayers based on molecular descriptors and random forest.

Welling SH, Clemmensen LK, Buckley ST, Hovgaard L, Brockhoff PB, Refsgaard HH.

Eur J Pharm Biopharm. 2015 Aug;94:152-9. doi: 10.1016/j.ejpb.2015.05.012. Epub 2015 May 21.

9.

Interaction with Mixed Micelles in the Intestine Attenuates the Permeation Enhancing Potential of Alkyl-Maltosides.

Gradauer K, Nishiumi A, Unrinin K, Higashino H, Kataoka M, Pedersen BL, Buckley ST, Yamashita S.

Mol Pharm. 2015 Jul 6;12(7):2245-53. doi: 10.1021/mp500776a. Epub 2015 Jun 23.

PMID:
25874852
10.

Expression and function of the epithelial sodium channel δ-subunit in human respiratory epithelial cells in vitro.

Schwagerus E, Sladek S, Buckley ST, Armas-Capote N, Alvarez de la Rosa D, Harvey BJ, Fischer H, Illek B, Huwer H, Schneider-Daum N, Lehr CM, Ehrhardt C.

Pflugers Arch. 2015 Nov;467(11):2257-73. doi: 10.1007/s00424-015-1693-5. Epub 2015 Feb 13.

PMID:
25677639
11.

Are hippocampal size differences in posttraumatic stress disorder mediated by sleep pathology?

Mohlenhoff BS, Chao LL, Buckley ST, Weiner MW, Neylan TC.

Alzheimers Dement. 2014 Jun;10(3 Suppl):S146-54. doi: 10.1016/j.jalz.2014.04.016.

12.

The role of citric acid in oral peptide and protein formulations: relationship between calcium chelation and proteolysis inhibition.

Welling SH, Hubálek F, Jacobsen J, Brayden DJ, Rahbek UL, Buckley ST.

Eur J Pharm Biopharm. 2014 Apr;86(3):544-51. doi: 10.1016/j.ejpb.2013.12.017. Epub 2013 Dec 31.

PMID:
24384069
13.

Biopharmaceutical classification of poorly soluble drugs with respect to "enabling formulations".

Buckley ST, Frank KJ, Fricker G, Brandl M.

Eur J Pharm Sci. 2013 Sep 27;50(1):8-16. doi: 10.1016/j.ejps.2013.04.002. Epub 2013 Apr 11. Review.

PMID:
23583787
14.

Oral bioavailability of ketoprofen in suspension and solution formulations in rats: the influence of poloxamer 188.

Fischer SM, Parmentier J, Buckley ST, Reimold I, Brandl M, Fricker G.

J Pharm Pharmacol. 2012 Nov;64(11):1631-7. doi: 10.1111/j.2042-7158.2012.01541.x. Epub 2012 Jun 20.

PMID:
23058050
15.

Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism.

Zhou B, Buckley ST, Patel V, Liu Y, Luo J, Krishnaveni MS, Ivan M, DeMaio L, Kim KJ, Ehrhardt C, Crandall ED, Borok Z.

PLoS One. 2012;7(6):e38827. doi: 10.1371/journal.pone.0038827. Epub 2012 Jun 20.

16.

Transport of the fluorescent organic cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cells.

Salomon JJ, Endter S, Tachon G, Falson F, Buckley ST, Ehrhardt C.

Eur J Pharm Biopharm. 2012 Jun;81(2):351-9. doi: 10.1016/j.ejpb.2012.03.001. Epub 2012 Mar 8.

PMID:
22426135
17.

In vitro models to evaluate the permeability of poorly soluble drug entities: challenges and perspectives.

Buckley ST, Fischer SM, Fricker G, Brandl M.

Eur J Pharm Sci. 2012 Feb 14;45(3):235-50. doi: 10.1016/j.ejps.2011.12.007. Epub 2011 Dec 8. Review.

PMID:
22178532
18.

Application of simulated intestinal fluid on the phospholipid vesicle-based drug permeation assay.

Fischer SM, Buckley ST, Kirchmeyer W, Fricker G, Brandl M.

Int J Pharm. 2012 Jan 17;422(1-2):52-8. doi: 10.1016/j.ijpharm.2011.10.026. Epub 2011 Oct 17.

PMID:
22027395
19.

Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition.

DeMaio L, Buckley ST, Krishnaveni MS, Flodby P, Dubourd M, Banfalvi A, Xing Y, Ehrhardt C, Minoo P, Zhou B, Crandall ED, Borok Z.

J Pathol. 2012 Mar;226(4):633-44. doi: 10.1002/path.3016. Epub 2011 Dec 9.

21.

Investigations into the fate of inhaled salmon calcitonin at the respiratory epithelial barrier.

Baginski L, Tewes F, Buckley ST, Healy AM, Bakowsky U, Ehrhardt C.

Pharm Res. 2012 Jan;29(1):332-41. doi: 10.1007/s11095-011-0553-z. Epub 2011 Aug 5.

PMID:
21818710
22.

Cytoskeletal re-arrangement in TGF-β1-induced alveolar epithelial-mesenchymal transition studied by atomic force microscopy and high-content analysis.

Buckley ST, Medina C, Davies AM, Ehrhardt C.

Nanomedicine. 2012 Apr;8(3):355-64. doi: 10.1016/j.nano.2011.06.021. Epub 2011 Jul 12.

PMID:
21756862
23.

Interplay between RAGE, CD44, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells.

Buckley ST, Medina C, Kasper M, Ehrhardt C.

Am J Physiol Lung Cell Mol Physiol. 2011 Apr;300(4):L548-59. doi: 10.1152/ajplung.00230.2010. Epub 2011 Jan 28.

24.

Differential susceptibility to epithelial-mesenchymal transition (EMT) of alveolar, bronchial and intestinal epithelial cells in vitro and the effect of angiotensin II receptor inhibition.

Buckley ST, Medina C, Ehrhardt C.

Cell Tissue Res. 2010 Oct;342(1):39-51. doi: 10.1007/s00441-010-1029-x. Epub 2010 Sep 17.

PMID:
20848133
25.

ASL perfusion MRI predicts cognitive decline and conversion from MCI to dementia.

Chao LL, Buckley ST, Kornak J, Schuff N, Madison C, Yaffe K, Miller BL, Kramer JH, Weiner MW.

Alzheimer Dis Assoc Disord. 2010 Jan-Mar;24(1):19-27. doi: 10.1097/WAD.0b013e3181b4f736.

26.

The receptor for advanced glycation end products (RAGE) and the lung.

Buckley ST, Ehrhardt C.

J Biomed Biotechnol. 2010;2010:917108. doi: 10.1155/2010/917108. Epub 2010 Jan 19. Review.

27.

Brain atrophy associated with baseline and longitudinal measures of cognition.

Cardenas VA, Chao LL, Studholme C, Yaffe K, Miller BL, Madison C, Buckley ST, Mungas D, Schuff N, Weiner MW.

Neurobiol Aging. 2011 Apr;32(4):572-80. doi: 10.1016/j.neurobiolaging.2009.04.011. Epub 2009 May 14.

28.

Evidence of neurodegeneration in brains of older adults who do not yet fulfill MCI criteria.

Chao LL, Mueller SG, Buckley ST, Peek K, Raptentsetseng S, Elman J, Yaffe K, Miller BL, Kramer JH, Madison C, Mungas D, Schuff N, Weiner MW.

Neurobiol Aging. 2010 Mar;31(3):368-77. doi: 10.1016/j.neurobiolaging.2008.05.004. Epub 2008 Jun 11.

29.

Genes and gene expression in the brains of human alcoholics.

Dodd PR, Buckley ST, Eckert AL, Foley PF, Innes DJ.

Ann N Y Acad Sci. 2006 Aug;1074:104-15.

PMID:
17105908
30.

GABA(A) receptor beta isoform protein expression in human alcoholic brain: interaction with genotype.

Buckley ST, Foley PF, Innes DJ, Loh el-W, Shen Y, Williams SM, Harper CG, Tannenberg AE, Dodd PR.

Neurochem Int. 2006 Nov;49(6):557-67.

PMID:
16766085
31.

Genes and gene expression in the brain of the alcoholic.

Dodd PR, Foley PF, Buckley ST, Eckert AL, Innes DJ.

Addict Behav. 2004 Sep;29(7):1295-309.

PMID:
15345266
32.

GABAA receptor beta subunit mRNA expression in the human alcoholic brain.

Buckley ST, Dodd PR.

Neurochem Int. 2004 Dec;45(7):1011-20.

PMID:
15337300
33.

Quantitation of human brain GABAA receptor beta isoforms by competitive RT-PCR.

Buckley ST, Dodd PR.

Brain Res Brain Res Protoc. 2003 Mar;11(1):19-26.

PMID:
12697259
34.

Expression and distribution of GABAA receptor subtypes in human alcoholic cerebral cortex.

Buckley ST, Eckert AL, Dodd PR.

Ann N Y Acad Sci. 2000 Sep;914:58-64.

PMID:
11085308

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