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Items: 1 to 50 of 102

1.

Silencing of genes required for glycosylphosphatidylinositol anchor biosynthesis in Burkitt lymphoma.

Hu R, Mukhina GL, Lee SH, Jones RJ, Englund PT, Brown P, Sharkis SJ, Buckley JT, Brodsky RA.

Exp Hematol. 2009 Apr;37(4):423-434.e2. doi: 10.1016/j.exphem.2009.01.003.

2.

A chimera of interleukin 2 and a binding variant of aerolysin is selectively toxic to cells displaying the interleukin 2 receptor.

Osusky M, Teschke L, Wang X, Wong K, Buckley JT.

J Biol Chem. 2008 Jan 18;283(3):1572-9. Epub 2007 Nov 2.

3.

A prostate-specific antigen-activated channel-forming toxin as therapy for prostatic disease.

Williams SA, Merchant RF, Garrett-Mayer E, Isaacs JT, Buckley JT, Denmeade SR.

J Natl Cancer Inst. 2007 Mar 7;99(5):376-85.

4.

The identification and structure of the membrane-spanning domain of the Clostridium septicum alpha toxin.

Melton JA, Parker MW, Rossjohn J, Buckley JT, Tweten RK.

J Biol Chem. 2004 Apr 2;279(14):14315-22. Epub 2004 Jan 10.

5.

Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells.

Sotgia F, Razani B, Bonuccelli G, Schubert W, Battista M, Lee H, Capozza F, Schubert AL, Minetti C, Buckley JT, Lisanti MP.

Mol Cell Biol. 2002 Jun;22(11):3905-26.

6.

Multilineage glycosylphosphatidylinositol anchor-deficient haematopoiesis in untreated aplastic anaemia.

Mukhina GL, Buckley JT, Barber JP, Jones RJ, Brodsky RA.

Br J Haematol. 2001 Nov;115(2):476-82.

PMID:
11703352
7.
8.

Channels formed by subnanomolar concentrations of the toxin aerolysin trigger apoptosis of T lymphomas.

Nelson KL, Brodsky RA, Buckley JT.

Cell Microbiol. 1999 Jul;1(1):69-74.

PMID:
11207542
9.

Lipids favoring inverted phase enhance the ability of aerolysin to permeabilize liposome bilayers.

Alonso A, Goñi FM, Buckley JT.

Biochemistry. 2000 Nov 21;39(46):14019-24.

PMID:
11087349
10.

The channel-forming protein proaerolysin remains a dimer at low concentrations in solution.

Barry R, Moore S, Alonso A, Ausió J, Buckley JT.

J Biol Chem. 2001 Jan 5;276(1):551-4.

11.

Improved detection and characterization of paroxysmal nocturnal hemoglobinuria using fluorescent aerolysin.

Brodsky RA, Mukhina GL, Li S, Nelson KL, Chiurazzi PL, Buckley JT, Borowitz MJ.

Am J Clin Pathol. 2000 Sep;114(3):459-66.

12.
13.

Clostridium septicum alpha toxin uses glycosylphosphatidylinositol-anchored protein receptors.

Gordon VM, Nelson KL, Buckley JT, Stevens VL, Tweten RK, Elwood PC, Leppla SH.

J Biol Chem. 1999 Sep 17;274(38):27274-80.

14.

Analysis of receptor binding by the channel-forming toxin aerolysin using surface plasmon resonance.

MacKenzie CR, Hirama T, Buckley JT.

J Biol Chem. 1999 Aug 6;274(32):22604-9.

15.

The channel-forming toxin aerolysin neutralizes human immunodeficiency virus type 1.

Nguyen DH, Liao Z, Buckley JT, Hildreth JE.

Mol Microbiol. 1999 Aug;33(3):659-66.

16.

Expression and properties of an aerolysin--Clostridium septicum alpha toxin hybrid protein.

Diep DB, Nelson KL, Lawrence TS, Sellman BR, Tweten RK, Buckley JT.

Mol Microbiol. 1999 Feb;31(3):785-94.

17.

Resistance of paroxysmal nocturnal hemoglobinuria cells to the glycosylphosphatidylinositol-binding toxin aerolysin.

Brodsky RA, Mukhina GL, Nelson KL, Lawrence TS, Jones RJ, Buckley JT.

Blood. 1999 Mar 1;93(5):1749-56.

PMID:
10029605
18.

The cytotoxic enterotoxin of Aeromonas hydrophila is aerolysin.

Buckley JT, Howard SP.

Infect Immun. 1999 Jan;67(1):466-7. No abstract available.

19.

The pore-forming toxin proaerolysin is activated by furin.

Abrami L, Fivaz M, Decroly E, Seidah NG, Jean F, Thomas G, Leppla SH, Buckley JT, van der Goot FG.

J Biol Chem. 1998 Dec 4;273(49):32656-61.

20.

Secretion and properties of the large and small lobes of the channel-forming toxin aerolysin.

Diep DB, Lawrence TS, Ausio J, Howard SP, Buckley JT.

Mol Microbiol. 1998 Oct;30(2):341-52.

21.

Aerolysin--a paradigm for membrane insertion of beta-sheet protein toxins?

Rossjohn J, Feil SC, McKinstry WJ, Tsernoglou D, van der Goot G, Buckley JT, Parker MW.

J Struct Biol. 1998;121(2):92-100. Review.

PMID:
9615432
22.

Movement of a loop in domain 3 of aerolysin is required for channel formation.

Rossjohn J, Raja SM, Nelson KL, Feil SC, van der Goot FG, Parker MW, Buckley JT.

Biochemistry. 1998 Jan 13;37(2):741-6.

PMID:
9425098
23.

Glycosylphosphatidylinositol anchors of membrane glycoproteins are binding determinants for the channel-forming toxin aerolysin.

Diep DB, Nelson KL, Raja SM, Pleshak EN, Buckley JT.

J Biol Chem. 1998 Jan 23;273(4):2355-60.

24.

Conformational changes in aerolysin during the transition from the water-soluble protoxin to the membrane channel.

Cabiaux V, Buckley JT, Wattiez R, Ruysschaert JM, Parker MW, van der Goot FG.

Biochemistry. 1997 Dec 9;36(49):15224-32.

PMID:
9398250
25.

The erythrocyte receptor for the channel-forming toxin aerolysin is a novel glycosylphosphatidylinositol-anchored protein.

Cowell S, Aschauer W, Gruber HJ, Nelson KL, Buckley JT.

Mol Microbiol. 1997 Jul;25(2):343-50.

26.

Aerolysin and pertussis toxin share a common receptor-binding domain.

Rossjohn J, Buckley JT, Hazes B, Murzin AG, Read RJ, Parker MW.

EMBO J. 1997 Jun 16;16(12):3426-34.

27.
28.
30.

Characterisation of the heptameric pore-forming complex of the Aeromonas toxin aerolysin using MALDI-TOF mass spectrometry.

Moniatte M, van der Goot FG, Buckley JT, Pattus F, van Dorsselaer A.

FEBS Lett. 1996 Apr 22;384(3):269-72.

31.
32.

Optical single-channel analysis of the aerolysin pore in erythrocyte membranes.

Tschödrich-Rotter M, Kubitscheck U, Ugochukwu G, Buckley JT, Peters R.

Biophys J. 1996 Feb;70(2):723-32.

33.

Aerolysin--the ins and outs of a model channel-forming toxin.

Parker MW, van der Goot FG, Buckley JT.

Mol Microbiol. 1996 Jan;19(2):205-12. Review.

PMID:
8825766
34.

A new family of lipolytic plant enzymes with members in rice, arabidopsis and maize.

Brick DJ, Brumlik MJ, Buckley JT, Cao JX, Davies PC, Misra S, Tranbarger TJ, Upton C.

FEBS Lett. 1995 Dec 27;377(3):475-80.

35.

Protonation of histidine-132 promotes oligomerization of the channel-forming toxin aerolysin.

Buckley JT, Wilmsen HU, Lesieur C, Schulze A, Pattus F, Parker MW, van der Goot FG.

Biochemistry. 1995 Dec 19;34(50):16450-5.

PMID:
8845373
36.

Vibrio spp. secrete proaerolysin as a folded dimer without the need for disulphide bond formation.

Hardie KR, Schulze A, Parker MW, Buckley JT.

Mol Microbiol. 1995 Sep;17(6):1035-44.

PMID:
8594324
37.

A new family of lipolytic enzymes?

Upton C, Buckley JT.

Trends Biochem Sci. 1995 May;20(5):178-9. No abstract available.

PMID:
7610479
38.

The C-terminal peptide produced upon proteolytic activation of the cytolytic toxin aerolysin is not involved in channel formation.

van der Goot FG, Hardie KR, Parker MW, Buckley JT.

J Biol Chem. 1994 Dec 2;269(48):30496-501.

39.

Partial purification of the rat erythrocyte receptor for the channel-forming toxin aerolysin and reconstitution into planar lipid bilayers.

Gruber HJ, Wilmsen HU, Cowell S, Schindler H, Buckley JT.

Mol Microbiol. 1994 Dec;14(5):1093-101.

PMID:
7536292
40.

Characterization of interfacial catalysis by Aeromonas hydrophila lipase/acyltransferase in the highly processive scooting mode.

Jain MK, Krause CD, Buckley JT, Bayburt T, Gelb MH.

Biochemistry. 1994 May 3;33(17):5011-20.

PMID:
8172876
41.

The cytolytic toxin aerolysin: from the soluble form to the transmembrane channel.

van der Goot FG, Pattus F, Parker M, Buckley JT.

Toxicology. 1994 Feb 28;87(1-3):19-28. Review.

PMID:
7512760
42.

Influence of active site and tyrosine modification on the secretion and activity of the Aeromonas hydrophila lipase/acyltransferase.

Robertson DL, Hilton S, Wong KR, Koepke A, Buckley JT.

J Biol Chem. 1994 Jan 21;269(3):2146-50.

43.

Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states.

Parker MW, Buckley JT, Postma JP, Tucker AD, Leonard K, Pattus F, Tsernoglou D.

Nature. 1994 Jan 20;367(6460):292-5.

PMID:
7510043
44.
46.

Dimerization stabilizes the pore-forming toxin aerolysin in solution.

van der Goot FG, Ausio J, Wong KR, Pattus F, Buckley JT.

J Biol Chem. 1993 Aug 25;268(24):18272-9.

47.

Oligomerization of the channel-forming toxin aerolysin precedes insertion into lipid bilayers.

van der Goot FG, Pattus F, Wong KR, Buckley JT.

Biochemistry. 1993 Mar 16;32(10):2636-42.

PMID:
7680572
48.

Purification of Aeromonas hydrophila major outer-membrane proteins: N-terminal sequence analysis and channel-forming properties.

Jeanteur D, Gletsu N, Pattus F, Buckley JT.

Mol Microbiol. 1992 Nov;6(22):3355-63.

PMID:
1283000
49.

Spectroscopic study of the activation and oligomerization of the channel-forming toxin aerolysin: identification of the site of proteolytic activation.

van der Goot FG, Lakey J, Pattus F, Kay CM, Sorokine O, Van Dorsselaer A, Buckley JT.

Biochemistry. 1992 Sep 15;31(36):8566-70.

PMID:
1382579
50.

The channel-forming toxin aerolysin.

Buckley JT.

FEMS Microbiol Immunol. 1992 Sep;5(1-3):13-7.

PMID:
1384593

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