Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 275

1.

11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy.

Fenton CG, Doig CL, Fareed S, Naylor A, Morrell AP, Addison O, Wehmeyer C, Buckley CD, Cooper MS, Lavery GG, Raza K, Hardy RS.

Arthritis Res Ther. 2019 Aug 16;21(1):188. doi: 10.1186/s13075-019-1972-1.

2.

Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol.

Al-Laith M, Jasenecova M, Abraham S, Bosworth A, Bruce IN, Buckley CD, Ciurtin C, D'Agostino MA, Emery P, Gaston H, Isaacs JD, Filer A, Fisher BA, Huizinga TWJ, Ho P, Jacklin C, Lempp H, McInnes IB, Pratt AG, Östor A, Raza K, Taylor PC, van Schaardenburg D, Shivapatham D, Wright AJ, Vasconcelos JC, Kelly J, Murphy C, Prevost AT, Cope AP.

Trials. 2019 Jul 15;20(1):429. doi: 10.1186/s13063-019-3403-7.

3.

Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology.

Nayar S, Campos J, Smith CG, Iannizzotto V, Gardner DH, Mourcin F, Roulois D, Turner J, Sylvestre M, Asam S, Glaysher B, Bowman SJ, Fearon DT, Filer A, Tarte K, Luther SA, Fisher BA, Buckley CD, Coles MC, Barone F.

Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13490-13497. doi: 10.1073/pnas.1905301116. Epub 2019 Jun 18.

4.

Distinct fibroblast subsets drive inflammation and damage in arthritis.

Croft AP, Campos J, Jansen K, Turner JD, Marshall J, Attar M, Savary L, Wehmeyer C, Naylor AJ, Kemble S, Begum J, Dürholz K, Perlman H, Barone F, McGettrick HM, Fearon DT, Wei K, Raychaudhuri S, Korsunsky I, Brenner MB, Coles M, Sansom SN, Filer A, Buckley CD.

Nature. 2019 Jun;570(7760):246-251. doi: 10.1038/s41586-019-1263-7. Epub 2019 May 29.

PMID:
31142839
5.

Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation.

Sun D, Stopka-Farooqui U, Barry S, Aksoy E, Parsonage G, Vossenkämper A, Capasso M, Wan X, Norris S, Marshall JL, Clear A, Gribben J, MacDonald TT, Buckley CD, Korbonits M, Haworth O.

Cell Rep. 2019 Apr 30;27(5):1461-1471.e4. doi: 10.1016/j.celrep.2019.04.014.

6.

Perceptions of first-degree relatives of patients with rheumatoid arthritis about lifestyle modifications and pharmacological interventions to reduce the risk of rheumatoid arthritis development: a qualitative interview study.

Simons G, Stack RJ, Stoffer-Marx M, Englbrecht M, Mosor E, Buckley CD, Kumar K, Hansson M, Hueber A, Stamm T, Falahee M, Raza K.

BMC Rheumatol. 2018 Nov 6;2:31. doi: 10.1186/s41927-018-0038-3. eCollection 2018.

7.

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients.

Humby F, Lewis M, Ramamoorthi N, Hackney JA, Barnes MR, Bombardieri M, Setiadi AF, Kelly S, Bene F, DiCicco M, Riahi S, Rocher V, Ng N, Lazarou I, Hands R, van der Heijde D, Landewé RBM, van der Helm-van Mil A, Cauli A, McInnes I, Buckley CD, Choy EH, Taylor PC, Townsend MJ, Pitzalis C.

Ann Rheum Dis. 2019 Jun;78(6):761-772. doi: 10.1136/annrheumdis-2018-214539. Epub 2019 Mar 16.

8.

Response to: 'Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis' by Cutolo et al.

Aungier S, Cartwright AJ, Schwenzer A, Marshall J, Dyson MR, Slavny P, Parthiban K, Karatt-Vellatt A, Sahbudin I, Culbert E, Hextall P, Clanchy FI, Williams R, Marsden BD, Raza K, Filer A, Buckley CD, McCafferty J, Midwood KS.

Ann Rheum Dis. 2019 Feb 12. pii: annrheumdis-2019-215108. doi: 10.1136/annrheumdis-2019-215108. [Epub ahead of print] No abstract available.

PMID:
30755416
9.

Tissue inflammation signatures point towards resolution in adhesive capsulitis.

Dakin SG, Rangan A, Martinez F, Brealey S, Northgraves M, Kottam L, Cooper C, Buckley CD, Carr AJ.

Rheumatology (Oxford). 2019 Jun 1;58(6):1109-1111. doi: 10.1093/rheumatology/kez007. No abstract available.

PMID:
30690632
10.

Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?

Aungier SR, Cartwright AJ, Schwenzer A, Marshall JL, Dyson MR, Slavny P, Parthiban K, Karatt-Vellatt A, Sahbudin I, Culbert E, Hextall P, Clanchy FI, Williams R, Marsden BD, Raza K, Filer A, Buckley CD, McCafferty J, Midwood KS.

Ann Rheum Dis. 2019 Feb;78(2):186-191. doi: 10.1136/annrheumdis-2018-214294. Epub 2018 Dec 14.

11.

Author Correction: Pathogenic stromal cells as therapeutic targets in joint inflammation.

Dakin SG, Coles M, Sherlock JP, Powrie F, Carr AJ, Buckley CD.

Nat Rev Rheumatol. 2019 Jan;15(1):61. doi: 10.1038/s41584-018-0134-1.

PMID:
30498256
12.

Phosphatidylinositol 3-kinase delta pathway: a novel therapeutic target for Sjögren's syndrome.

Nayar S, Campos J, Smith CG, Iannizzotto V, Gardner DH, Colafrancesco S, Pipi E, Kollert F, Hunter KJ, Brewer C, Buckley CD, Bowman SJ, Priori R, Valesini G, Juarez M, Fahy WA, Fisher BA, Payne A, Allen RA, Barone F.

Ann Rheum Dis. 2019 Feb;78(2):249-260. doi: 10.1136/annrheumdis-2017-212619. Epub 2018 Nov 24.

13.

Pathogenic stromal cells as therapeutic targets in joint inflammation.

Dakin SG, Coles M, Sherlock JP, Powrie F, Carr AJ, Buckley CD.

Nat Rev Rheumatol. 2018 Dec;14(12):714-726. doi: 10.1038/s41584-018-0112-7. Review. Erratum in: Nat Rev Rheumatol. 2019 Jan;15(1):61.

PMID:
30420750
14.

Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts.

Pearson MJ, Bik MA, Ospelt C, Naylor AJ, Wehmeyer C, Jones SW, Buckley CD, Gay S, Filer A, Lord JM.

Sci Rep. 2018 Aug 27;8(1):12887. doi: 10.1038/s41598-018-31173-3.

15.

Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis.

Bustamante MF, Oliveira PG, Garcia-Carbonell R, Croft AP, Smith JM, Serrano RL, Sanchez-Lopez E, Liu X, Kisseleva T, Hay N, Buckley CD, Firestein GS, Murphy AN, Miyamoto S, Guma M.

Ann Rheum Dis. 2018 Nov;77(11):1636-1643. doi: 10.1136/annrheumdis-2018-213103. Epub 2018 Jul 30.

PMID:
30061164
16.

Leukocyte trafficking between stromal compartments: lessons from rheumatoid arthritis.

Buckley CD, McGettrick HM.

Nat Rev Rheumatol. 2018 Aug;14(8):476-487. doi: 10.1038/s41584-018-0042-4. Review.

PMID:
30002464
17.

Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis.

Huang HY, Rivas-Caicedo A, Renevey F, Cannelle H, Peranzoni E, Scarpellino L, Hardie DL, Pommier A, Schaeuble K, Favre S, Vogt TK, Arenzana-Seisdedos F, Schneider P, Buckley CD, Donnadieu E, Luther SA.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6826-E6835. doi: 10.1073/pnas.1712628115. Epub 2018 Jul 2.

18.

Induction and transcriptional regulation of the co-inhibitory gene module in T cells.

Chihara N, Madi A, Kondo T, Zhang H, Acharya N, Singer M, Nyman J, Marjanovic ND, Kowalczyk MS, Wang C, Kurtulus S, Law T, Etminan Y, Nevin J, Buckley CD, Burkett PR, Buenrostro JD, Rozenblatt-Rosen O, Anderson AC, Regev A, Kuchroo VK.

Nature. 2018 Jun;558(7710):454-459. doi: 10.1038/s41586-018-0206-z. Epub 2018 Jun 13.

19.

11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.

Hardy RS, Fenton C, Croft AP, Naylor AJ, Begum R, Desanti G, Buckley CD, Lavery G, Cooper MS, Raza K.

J Autoimmun. 2018 Aug;92:104-113. doi: 10.1016/j.jaut.2018.05.010. Epub 2018 Jun 8.

20.

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis.

Karouzakis E, Raza K, Kolling C, Buckley CD, Gay S, Filer A, Ospelt C.

Sci Rep. 2018 May 9;8(1):7370. doi: 10.1038/s41598-018-24240-2.

21.

Stroma: the forgotten cells of innate immune memory.

Crowley T, Buckley CD, Clark AR.

Clin Exp Immunol. 2018 Jul;193(1):24-36. doi: 10.1111/cei.13149. Review.

22.

The role of ultrasound-defined tenosynovitis and synovitis in the prediction of rheumatoid arthritis development.

Sahbudin I, Pickup L, Nightingale P, Allen G, Cader Z, Singh R, de Pablo P, Buckley CD, Raza K, Filer A.

Rheumatology (Oxford). 2018 Apr 3. doi: 10.1093/rheumatology/key025. [Epub ahead of print]

23.

Review: Synovial Cell Metabolism and Chronic Inflammation in Rheumatoid Arthritis.

Falconer J, Murphy AN, Young SP, Clark AR, Tiziani S, Guma M, Buckley CD.

Arthritis Rheumatol. 2018 Jul;70(7):984-999. doi: 10.1002/art.40504. Epub 2018 Jun 4. Review.

24.

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis.

Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, Goodman SM, Bykerk VP, Ivashkiv LB, Lederer JA, Hacohen N, Nigrovic PA, Filer A, Buckley CD, Raychaudhuri S, Brenner MB.

Nat Commun. 2018 Feb 23;9(1):789. doi: 10.1038/s41467-018-02892-y.

25.

Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis.

Mandelin AM 2nd, Homan PJ, Shaffer AM, Cuda CM, Dominguez ST, Bacalao E, Carns M, Hinchcliff M, Lee J, Aren K, Thakrar A, Montgomery AB, Bridges SL Jr, Bathon JM, Atkinson JP, Fox DA, Matteson EL, Buckley CD, Pitzalis C, Parks D, Hughes LB, Geraldino-Pardilla L, Ike R, Phillips K, Wright K, Filer A, Kelly S, Ruderman EM, Morgan V, Abdala-Valencia H, Misharin AV, Budinger GS, Bartom ET, Pope RM, Perlman H, Winter DR.

Arthritis Rheumatol. 2018 Jun;70(6):841-854. doi: 10.1002/art.40453. Epub 2018 May 3.

26.

The new aims and scope of Arthritis Research & Therapy.

Buckley CD, Perlman H.

Arthritis Res Ther. 2018 Feb 7;20(1):19. doi: 10.1186/s13075-018-1518-y. No abstract available.

27.

Corrigendum: Synovial tissue research: a state-of-the-art review.

Orr C, Vieira-Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Goff BL, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Tas SW, Thurlings R, Fonseca JE, Veale DJ.

Nat Rev Rheumatol. 2017 Dec 19;14(1):60. doi: 10.1038/nrrheum.2017.206.

PMID:
29255214
28.

IgG1 Is Required for Optimal Protection after Immunization with the Purified Porin OmpD from Salmonella Typhimurium.

Zhang Y, Dominguez-Medina C, Cumley NJ, Heath JN, Essex SJ, Bobat S, Schager A, Goodall M, Kracker S, Buckley CD, May RC, Kingsley RA, MacLennan CA, López-Macías C, Cunningham AF, Toellner KM.

J Immunol. 2017 Dec 15;199(12):4103-4109. doi: 10.4049/jimmunol.1700952. Epub 2017 Nov 10.

29.

A qualitative exploration of physical, mental and ocular fatigue in patients with primary Sjögren's Syndrome.

Stack RJ, Southworth S, Fisher BA, Barone F, Buckley CD, Rauz S, Bowman SJ.

PLoS One. 2017 Oct 31;12(10):e0187272. doi: 10.1371/journal.pone.0187272. eCollection 2017.

30.

Synovial tissue research: a state-of-the-art review.

Orr C, Vieira-Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Le Goff B, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Thurlings R, Fonseca JE, Veale DJ.

Nat Rev Rheumatol. 2017 Sep 22;13(10):630. doi: 10.1038/nrrheum.2017.161.

PMID:
28935945
31.

Identification of a transitional fibroblast function in very early rheumatoid arthritis.

Filer A, Ward LSC, Kemble S, Davies CS, Munir H, Rogers R, Raza K, Buckley CD, Nash GB, McGettrick HM.

Ann Rheum Dis. 2017 Dec;76(12):2105-2112. doi: 10.1136/annrheumdis-2017-211286. Epub 2017 Aug 28.

32.

Vinculin forms a directionally asymmetric catch bond with F-actin.

Huang DL, Bax NA, Buckley CD, Weis WI, Dunn AR.

Science. 2017 Aug 18;357(6352):703-706. doi: 10.1126/science.aan2556.

33.

Stromal cell markers are differentially expressed in the synovial tissue of patients with early arthritis.

Choi IY, Karpus ON, Turner JD, Hardie D, Marshall JL, de Hair MJH, Maijer KI, Tak PP, Raza K, Hamann J, Buckley CD, Gerlag DM, Filer A.

PLoS One. 2017 Aug 9;12(8):e0182751. doi: 10.1371/journal.pone.0182751. eCollection 2017.

34.

Synovial tissue research: a state-of-the-art review.

Orr C, Vieira-Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Le Goff B, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Thurlings R, Fonseca JE, Veale DJ, Tas SW.

Nat Rev Rheumatol. 2017 Aug;13(8):463-475. doi: 10.1038/nrrheum.2017.115. Epub 2017 Jul 13. Review. Erratum in: Nat Rev Rheumatol. 2017 Sep 22;13(10 ):630. Nat Rev Rheumatol. 2017 Dec 19;14 (1):60.

PMID:
28701760
35.

Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface.

Khan KA, Naylor AJ, Khan A, Noy PJ, Mambretti M, Lodhia P, Athwal J, Korzystka A, Buckley CD, Willcox BE, Mohammed F, Bicknell R.

Oncogene. 2017 Nov 2;36(44):6097-6108. doi: 10.1038/onc.2017.214. Epub 2017 Jul 3.

36.

The evolution of an ancient technology.

Buckley CD, Boudot E.

R Soc Open Sci. 2017 May 31;4(5):170208. doi: 10.1098/rsos.170208. eCollection 2017 May.

37.

The role of stromal cells in inflammatory bone loss.

Wehmeyer C, Pap T, Buckley CD, Naylor AJ.

Clin Exp Immunol. 2017 Jul;189(1):1-11. doi: 10.1111/cei.12979. Epub 2017 May 18. Review.

38.

Genomic Responses of Mouse Synovial Fibroblasts During Tumor Necrosis Factor-Driven Arthritogenesis Greatly Mimic Those in Human Rheumatoid Arthritis.

Ntougkos E, Chouvardas P, Roumelioti F, Ospelt C, Frank-Bertoncelj M, Filer A, Buckley CD, Gay S, Nikolaou C, Kollias G.

Arthritis Rheumatol. 2017 Aug;69(8):1588-1600. doi: 10.1002/art.40128. Epub 2017 Jul 5.

39.

Pre-symptomatic autoimmunity in rheumatoid arthritis: when does the disease start?

Tracy A, Buckley CD, Raza K.

Semin Immunopathol. 2017 Jun;39(4):423-435. doi: 10.1007/s00281-017-0620-6. Epub 2017 Mar 23. Review.

40.

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions.

Frank-Bertoncelj M, Trenkmann M, Klein K, Karouzakis E, Rehrauer H, Bratus A, Kolling C, Armaka M, Filer A, Michel BA, Gay RE, Buckley CD, Kollias G, Gay S, Ospelt C.

Nat Commun. 2017 Mar 23;8:14852. doi: 10.1038/ncomms14852.

41.

Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo.

O'Neil JD, Ross EA, Ridley ML, Ding Q, Tang T, Rosner DR, Crowley T, Malhi D, Dean JL, Smallie T, Buckley CD, Clark AR.

Mol Cell Biol. 2017 May 16;37(11). pii: e00536-16. doi: 10.1128/MCB.00536-16. Print 2017 Jun 1.

42.

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update.

Smolen JS, Landewé R, Bijlsma J, Burmester G, Chatzidionysiou K, Dougados M, Nam J, Ramiro S, Voshaar M, van Vollenhoven R, Aletaha D, Aringer M, Boers M, Buckley CD, Buttgereit F, Bykerk V, Cardiel M, Combe B, Cutolo M, van Eijk-Hustings Y, Emery P, Finckh A, Gabay C, Gomez-Reino J, Gossec L, Gottenberg JE, Hazes JMW, Huizinga T, Jani M, Karateev D, Kouloumas M, Kvien T, Li Z, Mariette X, McInnes I, Mysler E, Nash P, Pavelka K, Poór G, Richez C, van Riel P, Rubbert-Roth A, Saag K, da Silva J, Stamm T, Takeuchi T, Westhovens R, de Wit M, van der Heijde D.

Ann Rheum Dis. 2017 Jun;76(6):960-977. doi: 10.1136/annrheumdis-2016-210715. Epub 2017 Mar 6. Review.

43.

Plasma Levels of Eicosapentaenoic Acid Are Associated with Anti-TNF Responsiveness in Rheumatoid Arthritis and Inhibit the Etanercept-driven Rise in Th17 Cell Differentiation in Vitro.

Jeffery L, Fisk HL, Calder PC, Filer A, Raza K, Buckley CD, McInnes I, Taylor PC, Fisher BA.

J Rheumatol. 2017 Jun;44(6):748-756. doi: 10.3899/jrheum.161068. Epub 2017 Feb 15.

PMID:
28202745
44.

Priming in response to pro-inflammatory cytokines is a feature of adult synovial but not dermal fibroblasts.

Crowley T, O'Neil JD, Adams H, Thomas AM, Filer A, Buckley CD, Clark AR.

Arthritis Res Ther. 2017 Feb 10;19(1):35. doi: 10.1186/s13075-017-1248-6.

45.

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.

Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Lee YC, Todd DJ, Bykerk VP, Goodman SM, Pernis AB, Ivashkiv LB, Karlson EW, Nigrovic PA, Filer A, Buckley CD, Lederer JA, Raychaudhuri S, Brenner MB.

Nature. 2017 Feb 1;542(7639):110-114. doi: 10.1038/nature20810.

46.

Persistent stromal fibroblast activation is present in chronic tendinopathy.

Dakin SG, Buckley CD, Al-Mossawi MH, Hedley R, Martinez FO, Wheway K, Watkins B, Carr AJ.

Arthritis Res Ther. 2017 Jan 25;19(1):16. doi: 10.1186/s13075-016-1218-4.

47.

Patients' Perceptions of Their Relatives' Risk of Developing Rheumatoid Arthritis and of the Potential for Risk Communication, Prediction, and Modulation.

Falahee M, Simons G, Buckley CD, Hansson M, Stack RJ, Raza K.

Arthritis Care Res (Hoboken). 2017 Oct;69(10):1558-1565. doi: 10.1002/acr.23179. Epub 2017 Sep 6.

48.

Patient and researcher perspectives on facilitating patient and public involvement in rheumatology research.

Pollock J, Raza K, Pratt AG, Hanson H, Siebert S, Filer A, Isaacs JD, Buckley CD, McInnes IB, Falahee M.

Musculoskeletal Care. 2017 Dec;15(4):395-399. doi: 10.1002/msc.1171. Epub 2016 Dec 16. No abstract available.

49.

Detection of antibodies to citrullinated tenascin-C in patients with early synovitis is associated with the development of rheumatoid arthritis.

Raza K, Schwenzer A, Juarez M, Venables P, Filer A, Buckley CD, Midwood KS.

RMD Open. 2016 Dec 1;2(2):e000318. eCollection 2016. No abstract available.

50.

Stromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation.

Barone F, Gardner DH, Nayar S, Steinthal N, Buckley CD, Luther SA.

Front Immunol. 2016 Nov 8;7:477. eCollection 2016. Review.

Supplemental Content

Loading ...
Support Center