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Items: 1 to 50 of 77

1.

Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen - Tuning Pharmacokinetic Properties and Exploring Dye-Protein Interaction.

Hensbergen AW, Buckle T, van Willigen DM, Schottelius M, Welling MM, van der Wijk FA, Maurer T, van der Poel HG, van der Pluijm G, van Weerden WM, Wester HJ, van Leeuwen FWB.

J Nucl Med. 2019 Sep 3. pii: jnumed.119.233064. doi: 10.2967/jnumed.119.233064. [Epub ahead of print]

PMID:
31481575
2.

Click Chemistry in the Design and Production of Hybrid Tracers.

Hensbergen AW, van Willigen DM, Welling MM, van der Wijk FA, de Korne CM, van Oosterom MN, Schottelius M, Wester HJ, Buckle T, van Leeuwen FWB.

ACS Omega. 2019 Jul 22;4(7):12438-12448. doi: 10.1021/acsomega.9b01484. eCollection 2019 Jul 31.

3.

Anatomical localization of radiocolloid tracer deposition affects outcome of sentinel node procedures in prostate cancer.

de Korne CM, Wit EM, de Jong J, Valdés Olmos RA, Buckle T, van Leeuwen FWB, van der Poel HG.

Eur J Nucl Med Mol Imaging. 2019 Aug 3. doi: 10.1007/s00259-019-04443-z. [Epub ahead of print]

PMID:
31377820
4.

High-resolution imaging and single-cell analysis via laser ablation-inductively coupled plasma-mass spectrometry for the determination of membranous receptor expression levels in breast cancer cell lines using receptor-specific hybrid tracers.

Van Acker T, Buckle T, Van Malderen SJM, van Willigen DM, van Unen V, van Leeuwen FWB, Vanhaecke F.

Anal Chim Acta. 2019 Oct 3;1074:43-53. doi: 10.1016/j.aca.2019.04.064. Epub 2019 Apr 29.

PMID:
31159938
5.

In vivo stability of supramolecular host-guest complexes monitored by dual-isotope multiplexing in a pre-targeting model of experimental liver radioembolization.

Welling MM, Spa SJ, van Willigen DM, Rietbergen DDD, Roestenberg M, Buckle T, van Leeuwen FWB.

J Control Release. 2019 Jan 10;293:126-134. doi: 10.1016/j.jconrel.2018.11.020. Epub 2018 Nov 25.

PMID:
30485797
6.

Synthesis and Preclinical Characterization of the PSMA-Targeted Hybrid Tracer PSMA-I&F for Nuclear and Fluorescence Imaging of Prostate Cancer.

Schottelius M, Wurzer A, Wissmiller K, Beck R, Koch M, Gorpas D, Notni J, Buckle T, van Oosterom MN, Steiger K, Ntziachristos V, Schwaiger M, van Leeuwen FWB, Wester HJ.

J Nucl Med. 2019 Jan;60(1):71-78. doi: 10.2967/jnumed.118.212720. Epub 2018 Sep 20.

7.

A prediction model relating the extent of intraoperative fascia preservation to erectile dysfunction after nerve-sparing robot-assisted radical prostatectomy.

KleinJan GH, Sikorska K, Korne CM, Brouwer OR, Buckle T, Tillier C, van der Roest RCM, de Jong J, van Leeuwen FWB, van der Poel HG.

J Robot Surg. 2019 Jun;13(3):455-462. doi: 10.1007/s11701-018-0867-5. Epub 2018 Sep 3.

PMID:
30178300
8.

The value of periprostatic fascia thickness and fascia preservation as prognostic factors of erectile function after nerve-sparing robot-assisted radical prostatectomy.

Grivas N, van der Roest RC, de Korne CM, KleinJan GH, Sikorska K, Schoots IG, Tillier C, van der Broek B, Jalink K, Heijmink SWTJP, Buckle T, van Leeuwen FWB, van der Poel HG.

World J Urol. 2019 Feb;37(2):309-315. doi: 10.1007/s00345-018-2387-3. Epub 2018 Jun 23.

PMID:
29936567
9.

Bioorthogonally Applicable Fluorescence Deactivation Strategy for Receptor Kinetics Study and Theranostic Pretargeting Approaches.

van der Wal S, de Korne CM, Sand LGL, van Willigen DM, Hogendoorn PCW, Szuhai K, van Leeuwen FWB, Buckle T.

Chembiochem. 2018 Jun 4. doi: 10.1002/cbic.201800229. [Epub ahead of print]

10.

Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2.

de Gooijer MC, de Vries NA, Buckle T, Buil LCM, Beijnen JH, Boogerd W, van Tellingen O.

Neoplasia. 2018 Jul;20(7):710-720. doi: 10.1016/j.neo.2018.05.001. Epub 2018 May 28.

11.

A Supramolecular Approach for Liver Radioembolization.

Spa SJ, Welling MM, van Oosterom MN, Rietbergen DDD, Burgmans MC, Verboom W, Huskens J, Buckle T, van Leeuwen FWB.

Theranostics. 2018 Mar 23;8(9):2377-2386. doi: 10.7150/thno.23567. eCollection 2018.

12.

The best of both worlds: a hybrid approach for optimal pre- and intraoperative identification of sentinel lymph nodes.

KleinJan GH, van Werkhoven E, van den Berg NS, Karakullukcu MB, Zijlmans HJMAA, van der Hage JA, van de Wiel BA, Buckle T, Klop WMC, Horenblas S, Valdés Olmos RA, van der Poel HG, van Leeuwen FWB.

Eur J Nucl Med Mol Imaging. 2018 Oct;45(11):1915-1925. doi: 10.1007/s00259-018-4028-x. Epub 2018 Apr 25.

13.

Tracers for Fluorescence-Guided Surgery: How Elongation of the Polymethine Chain in Cyanine Dyes Alters the Pharmacokinetics of a Dual-Modality c[RGDyK] Tracer.

Buckle T, van Willigen DM, Spa SJ, Hensbergen AW, van der Wal S, de Korne CM, Welling MM, van der Poel HG, Hardwick JCH, van Leeuwen FWB.

J Nucl Med. 2018 Jun;59(6):986-992. doi: 10.2967/jnumed.117.205575. Epub 2018 Feb 15.

14.

Multispectral fluorescence guided surgery; a feasibility study in a phantom using a clinical-grade laparoscopic camera system.

van Willigen DM, van den Berg NS, Buckle T, KleinJan GH, Hardwick JC, van der Poel HG, van Leeuwen FW.

Am J Nucl Med Mol Imaging. 2017 Jul 15;7(3):138-147. eCollection 2017.

15.

Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma.

Sand LGL, Buckle T, van Leeuwen FWB, Corver WE, Kruisselbrink AB, Jochemsen AG, Hogendoorn PCW, Szuhai K.

BMC Cancer. 2017 May 26;17(1):383. doi: 10.1186/s12885-017-3352-z.

16.

Hybrid Imaging Labels: Providing the Link Between Mass Spectrometry-Based Molecular Pathology and Theranostics.

Buckle T, van der Wal S, van Malderen SJ, Müller L, Kuil J, van Unen V, Peters RJ, van Bemmel ME, McDonnell LA, Velders AH, Koning F, Vanhaeke F, van Leeuwen FW.

Theranostics. 2017 Jan 12;7(3):624-633. doi: 10.7150/thno.17484. eCollection 2017.

17.

Obtaining control of cell surface functionalizations via Pre-targeting and Supramolecular host guest interactions.

Rood MT, Spa SJ, Welling MM, Ten Hove JB, van Willigen DM, Buckle T, Velders AH, van Leeuwen FW.

Sci Rep. 2017 Jan 6;7:39908. doi: 10.1038/srep39908.

18.

Diffusion-weighted-preparation (D-prep) MRI as a future extension of SPECT/CT based surgical planning for sentinel node procedures in the head and neck area?

Buckle T, KleinJan GH, Engelen T, van den Berg NS, DeRuiter MC, van der Heide U, Valdes Olmos RA, Webb A, van Buchem MA, Balm AJ, van Leeuwen FW.

Oral Oncol. 2016 Sep;60:48-54. doi: 10.1016/j.oraloncology.2016.06.015. Epub 2016 Jul 7.

PMID:
27531872
19.

Multispectral Fluorescence Imaging During Robot-assisted Laparoscopic Sentinel Node Biopsy: A First Step Towards a Fluorescence-based Anatomic Roadmap.

van den Berg NS, Buckle T, KleinJan GH, van der Poel HG, van Leeuwen FWB.

Eur Urol. 2017 Jul;72(1):110-117. doi: 10.1016/j.eururo.2016.06.012. Epub 2016 Jun 23.

PMID:
27345689
20.

Tailoring Fluorescent Dyes To Optimize a Hybrid RGD-Tracer.

Bunschoten A, van Willigen DM, Buckle T, van den Berg NS, Welling MM, Spa SJ, Wester HJ, van Leeuwen FW.

Bioconjug Chem. 2016 May 18;27(5):1253-8. doi: 10.1021/acs.bioconjchem.6b00093. Epub 2016 Apr 28.

PMID:
27074375
21.

Hybrid surgical guidance based on the integration of radionuclear and optical technologies.

van Leeuwen FW, Valdés-Olmos R, Buckle T, Vidal-Sicart S.

Br J Radiol. 2016 Jun;89(1062):20150797. doi: 10.1259/bjr.20150797. Epub 2016 Mar 4. Review.

22.

Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met.

Burggraaf J, Kamerling IM, Gordon PB, Schrier L, de Kam ML, Kales AJ, Bendiksen R, Indrevoll B, Bjerke RM, Moestue SA, Yazdanfar S, Langers AM, Swaerd-Nordmo M, Torheim G, Warren MV, Morreau H, Voorneveld PW, Buckle T, van Leeuwen FW, Ødegårdstuen LI, Dalsgaard GT, Healey A, Hardwick JC.

Nat Med. 2015 Aug;21(8):955-61. doi: 10.1038/nm.3641. Epub 2015 Jul 13.

PMID:
26168295
23.

Increased levels of choline metabolites are an early marker of docetaxel treatment response in BRCA1-mutated mouse mammary tumors: an assessment by ex vivo proton magnetic resonance spectroscopy.

van Asten JJ, Vettukattil R, Buckle T, Rottenberg S, van Leeuwen F, Bathen TF, Heerschap A.

J Transl Med. 2015 Apr 9;13:114. doi: 10.1186/s12967-015-0458-4.

24.

Development of a Hybrid Tracer for SPECT and Optical Imaging of Bacterial Infections.

Welling MM, Bunschoten A, Kuil J, Nelissen RG, Beekman FJ, Buckle T, van Leeuwen FW.

Bioconjug Chem. 2015 May 20;26(5):839-49. doi: 10.1021/acs.bioconjchem.5b00062. Epub 2015 Apr 20.

PMID:
25853214
25.

U-SPECT-BioFluo: an integrated radionuclide, bioluminescence, and fluorescence imaging platform.

van Oosterom MN, Kreuger R, Buckle T, Mahn WA, Bunschoten A, Josephson L, van Leeuwen FW, Beekman FJ.

EJNMMI Res. 2014 Oct 11;4:56. doi: 10.1186/s13550-014-0056-0. eCollection 2014.

26.

An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime.

Rood MT, Oikonomou M, Buckle T, Raspe M, Urano Y, Jalink K, Velders AH, van Leeuwen FW.

Chem Commun (Camb). 2014 Sep 4;50(68):9733-6. doi: 10.1039/c4cc04015e.

PMID:
25019263
27.

Fluorescent lectins for local in vivo visualization of peripheral nerves.

KleinJan GH, Buckle T, van Willigen DM, van Oosterom MN, Spa SJ, Kloosterboer HE, van Leeuwen FW.

Molecules. 2014 Jul 8;19(7):9876-92. doi: 10.3390/molecules19079876.

28.

Hybrid tracers for sentinel node biopsy.

Van Den Berg NS, Buckle T, Kleinjan GI, Klop WM, Horenblas S, Van Der Poel HG, Valdés-Olmos RA, Van Leeuwen FI.

Q J Nucl Med Mol Imaging. 2014 Jun;58(2):193-206. Review.

PMID:
24835293
29.

Use of a single hybrid imaging agent for integration of target validation with in vivo and ex vivo imaging of mouse tumor lesions resembling human DCIS.

Buckle T, Kuil J, van den Berg NS, Bunschoten A, Lamb HJ, Yuan H, Josephson L, Jonkers J, Borowsky AD, van Leeuwen FW.

PLoS One. 2013;8(1):e48324. doi: 10.1371/journal.pone.0048324. Epub 2013 Jan 11.

30.

Re: Steven Joniau, Laura Van den Bergh, Evelyne Lerut, et al. Mapping of pelvic lymph node metastases in prostate cancer. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2012.06.057.

van der Poel HG, Buckle T, Valdes Olmos R.

Eur Urol. 2013 Feb;63(2):e20. doi: 10.1016/j.eururo.2012.10.045. Epub 2012 Nov 2. No abstract available.

PMID:
23153744
31.

Multispectral visualization of surgical safety-margins using fluorescent marker seeds.

Chin PT, Beekman CA, Buckle T, Josephson L, van Leeuwen FW.

Am J Nucl Med Mol Imaging. 2012;2(2):151-62. Epub 2012 Mar 28.

32.

Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist.

Buckle T, van Berg NS, Kuil J, Bunschoten A, Oldenburg J, Borowsky AD, Wesseling J, Masada R, Oishi S, Fujii N, van Leeuwen FW.

Am J Nucl Med Mol Imaging. 2012;2(1):99-109. Epub 2011 Dec 15.

33.

Imaging agents for the chemokine receptor 4 (CXCR4).

Kuil J, Buckle T, van Leeuwen FW.

Chem Soc Rev. 2012 Aug 7;41(15):5239-61. doi: 10.1039/c2cs35085h. Epub 2012 Jun 28. Review.

PMID:
22743644
34.

Comparing the hybrid fluorescent-radioactive tracer indocyanine green-99mTc-nanocolloid with 99mTc-nanocolloid for sentinel node identification: a validation study using lymphoscintigraphy and SPECT/CT.

Brouwer OR, Buckle T, Vermeeren L, Klop WM, Balm AJ, van der Poel HG, van Rhijn BW, Horenblas S, Nieweg OE, van Leeuwen FW, Valdés Olmos RA.

J Nucl Med. 2012 Jul;53(7):1034-40. doi: 10.2967/jnumed.112.103127. Epub 2012 May 29.

35.

Relationship between intraprostatic tracer deposits and sentinel lymph node mapping in prostate cancer patients.

Buckle T, Brouwer OR, Valdés Olmos RA, van der Poel HG, van Leeuwen FW.

J Nucl Med. 2012 Jul;53(7):1026-33. doi: 10.2967/jnumed.111.098517. Epub 2012 May 29.

36.

Image navigation as a means to expand the boundaries of fluorescence-guided surgery.

Brouwer OR, Buckle T, Bunschoten A, Kuil J, Vahrmeijer AL, Wendler T, Valdés-Olmos RA, van der Poel HG, van Leeuwen FW.

Phys Med Biol. 2012 May 21;57(10):3123-36. doi: 10.1088/0031-9155/57/10/3123. Epub 2012 May 1.

PMID:
22547491
37.

Multimodal interventional molecular imaging of tumor margins and distant metastases by targeting αvβ3 integrin.

Bunschoten A, Buckle T, Visser NL, Kuil J, Yuan H, Josephson L, Vahrmeijer AL, van Leeuwen FW.

Chembiochem. 2012 May 7;13(7):1039-45. doi: 10.1002/cbic.201200034. Epub 2012 Apr 13.

38.

Phosphorescence imaging of living cells with amino acid-functionalized tris(2-phenylpyridine)iridium(III) complexes.

Steunenberg P, Ruggi A, van den Berg NS, Buckle T, Kuil J, van Leeuwen FW, Velders AH.

Inorg Chem. 2012 Feb 20;51(4):2105-14. doi: 10.1021/ic201860s. Epub 2012 Feb 3.

PMID:
22303934
39.

Feasibility of sentinel node biopsy in head and neck melanoma using a hybrid radioactive and fluorescent tracer.

Brouwer OR, Klop WM, Buckle T, Vermeeren L, van den Brekel MW, Balm AJ, Nieweg OE, Valdés Olmos RA, van Leeuwen FW.

Ann Surg Oncol. 2012 Jun;19(6):1988-94. doi: 10.1245/s10434-011-2180-7. Epub 2011 Dec 30.

40.

Hybrid peptide dendrimers for imaging of chemokine receptor 4 (CXCR4) expression.

Kuil J, Buckle T, Oldenburg J, Yuan H, Borowsky AD, Josephson L, van Leeuwen FW.

Mol Pharm. 2011 Dec 5;8(6):2444-53. doi: 10.1021/mp200401p. Epub 2011 Nov 15.

41.

Targeted non-covalent self-assembled nanoparticles based on human serum albumin.

Bunschoten A, Buckle T, Kuil J, Luker GD, Luker KE, Nieweg OE, van Leeuwen FW.

Biomaterials. 2012 Jan;33(3):867-75. doi: 10.1016/j.biomaterials.2011.10.005. Epub 2011 Oct 22.

42.

Immunohistochemical detection of the CXCR4 expression in tumor tissue using the fluorescent peptide antagonist Ac-TZ14011-FITC.

van den Berg NS, Buckle T, Kuil J, Wesseling J, van Leeuwen FW.

Transl Oncol. 2011 Aug;4(4):234-40. Epub 2011 Aug 1.

43.

Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide.

Kuil J, Buckle T, Yuan H, van den Berg NS, Oishi S, Fujii N, Josephson L, van Leeuwen FW.

Bioconjug Chem. 2011 May 18;22(5):859-64. doi: 10.1021/bc2000947. Epub 2011 Apr 19.

44.

Intraoperative laparoscopic fluorescence guidance to the sentinel lymph node in prostate cancer patients: clinical proof of concept of an integrated functional imaging approach using a multimodal tracer.

van der Poel HG, Buckle T, Brouwer OR, Valdés Olmos RA, van Leeuwen FW.

Eur Urol. 2011 Oct;60(4):826-33. doi: 10.1016/j.eururo.2011.03.024. Epub 2011 Apr 1.

PMID:
21458154
45.

Tracer-cocktail injections for combined pre- and intraoperative multimodal imaging of lymph nodes in a spontaneous mouse prostate tumor model.

van Leeuwen AC, Buckle T, Bendle G, Vermeeren L, Valdés Olmos R, van de Poel HG, van Leeuwen FW.

J Biomed Opt. 2011 Jan-Feb;16(1):016004. doi: 10.1117/1.3528027.

46.

Questioning the value of (99m)Tc-HYNIC-annexin V based response monitoring after docetaxel treatment in a mouse model for hereditary breast cancer.

Beekman CA, Buckle T, van Leeuwen AC, Valdés Olmos RA, Verheij M, Rottenberg S, van Leeuwen FW.

Appl Radiat Isot. 2011 Apr;69(4):656-62. doi: 10.1016/j.apradiso.2010.12.012. Epub 2010 Dec 25.

PMID:
21227707
47.

(Non-targeted) radioactive/fluorescent nanoparticles and their potential in combined pre- and intraoperative imaging during sentinel lymph node resection.

Buckle T, Chin PT, van Leeuwen FW.

Nanotechnology. 2010 Dec 3;21(48):482001. doi: 10.1088/0957-4484/21/48/482001. Epub 2010 Nov 10. Review.

PMID:
21063057
48.

Tumor bracketing and safety margin estimation using multimodal marker seeds: a proof of concept.

Buckle T, Chin PT, van den Berg NS, Loo CE, Koops W, Gilhuijs KG, van Leeuwen FW.

J Biomed Opt. 2010 Sep-Oct;15(5):056021. doi: 10.1117/1.3503955.

49.

Restricted brain penetration of the tyrosine kinase inhibitor erlotinib due to the drug transporters P-gp and BCRP.

de Vries NA, Buckle T, Zhao J, Beijnen JH, Schellens JH, van Tellingen O.

Invest New Drugs. 2012 Apr;30(2):443-9. doi: 10.1007/s10637-010-9569-1. Epub 2010 Oct 21.

PMID:
20963470
50.

A self-assembled multimodal complex for combined pre- and intraoperative imaging of the sentinel lymph node.

Buckle T, van Leeuwen AC, Chin PT, Janssen H, Muller SH, Jonkers J, van Leeuwen FW.

Nanotechnology. 2010 Sep 3;21(35):355101. doi: 10.1088/0957-4484/21/35/355101. Epub 2010 Aug 6.

PMID:
20689167

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