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Items: 1 to 50 of 71

1.

Calcium signalling in mammalian cell lines expressing wild type and mutant human α1-Antitrypsin.

Malintan NT, Buckingham SD, Lomas DA, Sattelle DB.

Sci Rep. 2019 Nov 21;9(1):17293. doi: 10.1038/s41598-019-53535-1.

2.

Insect toxins - selective pharmacological tools and drug/chemical leads.

Kachel HS, Buckingham SD, Sattelle DB.

Curr Opin Insect Sci. 2018 Dec;30:93-98. doi: 10.1016/j.cois.2018.10.001. Epub 2018 Oct 9. Review.

PMID:
30553492
3.

Improved reference genome of Aedes aegypti informs arbovirus vector control.

Matthews BJ, Dudchenko O, Kingan SB, Koren S, Antoshechkin I, Crawford JE, Glassford WJ, Herre M, Redmond SN, Rose NH, Weedall GD, Wu Y, Batra SS, Brito-Sierra CA, Buckingham SD, Campbell CL, Chan S, Cox E, Evans BR, Fansiri T, Filipović I, Fontaine A, Gloria-Soria A, Hall R, Joardar VS, Jones AK, Kay RGG, Kodali VK, Lee J, Lycett GJ, Mitchell SN, Muehling J, Murphy MR, Omer AD, Partridge FA, Peluso P, Aiden AP, Ramasamy V, Rašić G, Roy S, Saavedra-Rodriguez K, Sharan S, Sharma A, Smith ML, Turner J, Weakley AM, Zhao Z, Akbari OS, Black WC 4th, Cao H, Darby AC, Hill CA, Johnston JS, Murphy TD, Raikhel AS, Sattelle DB, Sharakhov IV, White BJ, Zhao L, Aiden EL, Mann RS, Lambrechts L, Powell JR, Sharakhova MV, Tu Z, Robertson HM, McBride CS, Hastie AR, Korlach J, Neafsey DE, Phillippy AM, Vosshall LB.

Nature. 2018 Nov;563(7732):501-507. doi: 10.1038/s41586-018-0692-z. Epub 2018 Nov 14.

4.

The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease.

Furutani S, Ihara M, Lees K, Buckingham SD, Partridge FA, David JA, Patel R, Warchal S, Mellor IR, Matsuda K, Sattelle DB.

Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):350-360. doi: 10.1016/j.ijpddr.2018.06.001. Epub 2018 Jun 4.

5.

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.

Partridge FA, Brown AE, Buckingham SD, Willis NJ, Wynne GM, Forman R, Else KJ, Morrison AA, Matthews JB, Russell AJ, Lomas DA, Sattelle DB.

Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):8-21. doi: 10.1016/j.ijpddr.2017.11.004. Epub 2017 Dec 2.

6.

Mechanisms of Action, Resistance and Toxicity of Insecticides Targeting GABA Receptors.

Buckingham SD, Ihara M, Sattelle DB, Matsuda K.

Curr Med Chem. 2017;24(27):2935-2945. doi: 10.2174/0929867324666170613075736. Review.

PMID:
28606041
7.

Modes of Action, Resistance and Toxicity of Insecticides Targeting Nicotinic Acetylcholine Receptors.

Ihara M, Buckingham SD, Matsuda K, Sattelle DB.

Curr Med Chem. 2017;24(27):2925-2934. doi: 10.2174/0929867324666170206142019. Review.

PMID:
28176635
8.

Genomic insights into the Ixodes scapularis tick vector of Lyme disease.

Gulia-Nuss M, Nuss AB, Meyer JM, Sonenshine DE, Roe RM, Waterhouse RM, Sattelle DB, de la Fuente J, Ribeiro JM, Megy K, Thimmapuram J, Miller JR, Walenz BP, Koren S, Hostetler JB, Thiagarajan M, Joardar VS, Hannick LI, Bidwell S, Hammond MP, Young S, Zeng Q, Abrudan JL, Almeida FC, Ayllón N, Bhide K, Bissinger BW, Bonzon-Kulichenko E, Buckingham SD, Caffrey DR, Caimano MJ, Croset V, Driscoll T, Gilbert D, Gillespie JJ, Giraldo-Calderón GI, Grabowski JM, Jiang D, Khalil SMS, Kim D, Kocan KM, Koči J, Kuhn RJ, Kurtti TJ, Lees K, Lang EG, Kennedy RC, Kwon H, Perera R, Qi Y, Radolf JD, Sakamoto JM, Sánchez-Gracia A, Severo MS, Silverman N, Šimo L, Tojo M, Tornador C, Van Zee JP, Vázquez J, Vieira FG, Villar M, Wespiser AR, Yang Y, Zhu J, Arensburger P, Pietrantonio PV, Barker SC, Shao R, Zdobnov EM, Hauser F, Grimmelikhuijzen CJP, Park Y, Rozas J, Benton R, Pedra JHF, Nelson DR, Unger MF, Tubio JMC, Tu Z, Robertson HM, Shumway M, Sutton G, Wortman JR, Lawson D, Wikel SK, Nene VM, Fraser CM, Collins FH, Birren B, Nelson KE, Caler E, Hill CA.

Nat Commun. 2016 Feb 9;7:10507. doi: 10.1038/ncomms10507.

9.

Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics.

Buckingham SD, Partridge FA, Sattelle DB.

Int J Parasitol Drugs Drug Resist. 2014 Oct 30;4(3):226-32. doi: 10.1016/j.ijpddr.2014.10.004. eCollection 2014 Dec. Review.

10.

Actions of agonists, fipronil and ivermectin on the predominant in vivo splice and edit variant (RDLbd, I/V) of the Drosophila GABA receptor expressed in Xenopus laevis oocytes.

Lees K, Musgaard M, Suwanmanee S, Buckingham SD, Biggin P, Sattelle D.

PLoS One. 2014 May 13;9(5):e97468. doi: 10.1371/journal.pone.0097468. eCollection 2014.

11.

Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans.

Glendinning SK, Buckingham SD, Sattelle DB, Wonnacott S, Wolstenholme AJ.

PLoS One. 2011;6(7):e22390. doi: 10.1371/journal.pone.0022390. Epub 2011 Jul 26.

12.

A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function.

Jones AK, Rayes D, Al-Diwani A, Maynard TP, Jones R, Hernando G, Buckingham SD, Bouzat C, Sattelle DB.

J Biol Chem. 2011 Jan 28;286(4):2550-8. doi: 10.1074/jbc.M110.177238. Epub 2010 Oct 21.

13.

A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds.

Sleigh JN, Buckingham SD, Esmaeili B, Viswanathan M, Cuppen E, Westlund BM, Sattelle DB.

Hum Mol Genet. 2011 Jan 15;20(2):245-60. doi: 10.1093/hmg/ddq459. Epub 2010 Oct 20.

PMID:
20962036
14.

Proteins interacting with nicotinic acetylcholine receptors: expanding functional and therapeutic horizons.

Jones AK, Buckingham SD, Sattelle DB.

Trends Pharmacol Sci. 2010 Oct;31(10):455-62. doi: 10.1016/j.tips.2010.07.001. Epub 2010 Jul 30. Review.

PMID:
20674046
15.

Allosteric modulation by benzodiazepines of GABA-gated chloride channels of an identified insect motor neurone.

Buckingham SD, Higashino Y, Sattelle DB.

Invert Neurosci. 2009 Nov;9(2):85-9. doi: 10.1007/s10158-009-0091-0. Epub 2009 Oct 22.

PMID:
19847463
16.

Alternative splicing of the Anopheles gambiae nicotinic acetylcholine receptor, Agamalphabeta9, generates both alpha and beta subunits.

Jones AK, Buckingham SD, Brown LA, Sattelle DB.

Invert Neurosci. 2009 Nov;9(2):77-84. doi: 10.1007/s10158-009-0089-7. Epub 2009 Aug 11.

PMID:
19669815
17.

Fast, automated measurement of nematode swimming (thrashing) without morphometry.

Buckingham SD, Sattelle DB.

BMC Neurosci. 2009 Jul 20;10:84. doi: 10.1186/1471-2202-10-84.

18.

Comparative pharmacology and computational modelling yield insights into allosteric modulation of human alpha7 nicotinic acetylcholine receptors.

Sattelle DB, Buckingham SD, Akamatsu M, Matsuda K, Pienaar IS, Jones AK, Sattelle BM, Almond A, Blundell CD.

Biochem Pharmacol. 2009 Oct 1;78(7):836-43. doi: 10.1016/j.bcp.2009.06.020. Epub 2009 Jun 21. Erratum in: Biochem Pharmacol. 2010 May 1;79(9):1372. Pienaar, Ilse [corrected to Pienaar, Ilse S].

PMID:
19549506
19.

Splice-variant- and stage-specific RNA editing of the Drosophila GABA receptor modulates agonist potency.

Jones AK, Buckingham SD, Papadaki M, Yokota M, Sattelle BM, Matsuda K, Sattelle DB.

J Neurosci. 2009 Apr 1;29(13):4287-92. doi: 10.1523/JNEUROSCI.5251-08.2009.

20.

Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.

Buckingham SD, Jones AK, Brown LA, Sattelle DB.

Pharmacol Rev. 2009 Mar;61(1):39-61. doi: 10.1124/pr.108.000562. Epub 2009 Mar 16. Review.

21.

Edited GluR2, a gatekeeper for motor neurone survival?

Buckingham SD, Kwak S, Jones AK, Blackshaw SE, Sattelle DB.

Bioessays. 2008 Nov;30(11-12):1185-92. doi: 10.1002/bies.20836. Review.

PMID:
18937367
22.

Strategies for automated analysis of C. elegans locomotion.

Buckingham SD, Sattelle DB.

Invert Neurosci. 2008 Sep;8(3):121-31. doi: 10.1007/s10158-008-0077-3. Epub 2008 Aug 8. Review.

PMID:
18688666
23.

Action potential shape change in an electrically coupled network during propagation: a computer simulation.

Buckingham SD, Spencer AN.

Invert Neurosci. 2008 Jun;8(2):83-9. doi: 10.1007/s10158-008-0071-9. Epub 2008 May 15.

PMID:
18481128
25.

Insect genomes: challenges and opportunities for neuroscience.

Sattelle DB, Jones AK, Buckingham SD.

Invert Neurosci. 2007 Sep;7(3):133-6. Review. No abstract available.

PMID:
17713800
26.

Actions of snake neurotoxins on an insect nicotinic cholinergic synapse.

Hue B, Buckingham SD, Buckingham D, Sattelle DB.

Invert Neurosci. 2007 Sep;7(3):173-8. Epub 2007 Aug 21.

PMID:
17710455
27.

Nicotinic acetylcholine receptors as drug/chemical targets, contributions from comparative genomics, forward and reverse genetics.

Sattelle DB, Jones AK, Brown LA, Buckingham SD, Mee CJ, Pym L.

SEB Exp Biol Ser. 2007;58:93-113. Review. No abstract available.

PMID:
17608238
28.

Neonicotinoid insecticides display partial and super agonist actions on native insect nicotinic acetylcholine receptors.

Brown LA, Ihara M, Buckingham SD, Matsuda K, Sattelle DB.

J Neurochem. 2006 Oct;99(2):608-15. Epub 2006 Aug 8.

29.
30.
31.

Oocytes as an expression system for studying receptor/channel targets of drugs and pesticides.

Buckingham SD, Pym L, Sattelle DB.

Methods Mol Biol. 2006;322:331-45. Review.

PMID:
16739734
32.

Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: nicotinic acetylcholine receptors, a case study.

Brown LA, Jones AK, Buckingham SD, Mee CJ, Sattelle DB.

Int J Parasitol. 2006 May 31;36(6):617-24. Epub 2006 Mar 6. Review.

PMID:
16620825
33.

Invertebrate studies and their ongoing contributions to neuroscience.

Sattelle DB, Buckingham SD.

Invert Neurosci. 2006 Mar;6(1):1-3. Review.

PMID:
16470388
34.

Atypical phenotypes from flatworm Kv3 channels.

Klassen TL, Buckingham SD, Atherton DM, Dacks JB, Gallin WJ, Spencer AN.

J Neurophysiol. 2006 May;95(5):3035-46. Epub 2006 Feb 1.

35.

Sgbeta1, a novel locust (Schistocerca gregaria) non-alpha nicotinic acetylcholine receptor-like subunit with homology to the Drosophila melanogaster Dbeta1 subunit.

Jones AK, Marshall J, Blake AD, Buckingham SD, Darlison MG, Sattelle DB.

Invert Neurosci. 2005 Nov;5(3-4):147-55. Epub 2005 Oct 24.

PMID:
16177887
36.

Data mining for protein-protein interactions in invertebrate model organisms.

Buckingham SD.

Invert Neurosci. 2005 Nov;5(3-4):183-7. Epub 2005 Oct 24.

PMID:
16158290
37.

Computer simulations of high-pass filtering in zebrafish larval muscle fibres.

Buckingham SD, Ali DW.

J Exp Biol. 2005 Aug;208(Pt 16):3055-63.

38.

Insect GABA receptors: splicing, editing, and targeting by antiparasitics and insecticides.

Buckingham SD, Biggin PC, Sattelle BM, Brown LA, Sattelle DB.

Mol Pharmacol. 2005 Oct;68(4):942-51. Epub 2005 Jul 18. Review.

PMID:
16027231
39.

Structure and function of two-pore-domain K+ channels: contributions from genetic model organisms.

Buckingham SD, Kidd JF, Law RJ, Franks CJ, Sattelle DB.

Trends Pharmacol Sci. 2005 Jul;26(7):361-7. Review.

PMID:
15939489
40.

Chemistry-to-gene screens in Caenorhabditis elegans.

Jones AK, Buckingham SD, Sattelle DB.

Nat Rev Drug Discov. 2005 Apr;4(4):321-30. Review.

PMID:
15803195
41.

A7DB: a relational database for mutational, physiological and pharmacological data related to the alpha7 nicotinic acetylcholine receptor.

Buckingham SD, Pym L, Jones AK, Brown L, Sansom MS, Sattelle DB, Biggin PC.

BMC Neurosci. 2005 Jan 20;6:2.

42.

RNA interference: from model organisms towards therapy for neural and neuromuscular disorders.

Buckingham SD, Esmaeili B, Wood M, Sattelle DB.

Hum Mol Genet. 2004 Oct 1;13 Spec No 2:R275-88. Review.

PMID:
15358735
43.

Sodium and potassium currents of larval zebrafish muscle fibres.

Buckingham SD, Ali DW.

J Exp Biol. 2004 Feb;207(Pt 5):841-52.

44.

Bicuculline-insensitive GABA-gated Cl- channels in the larval nervous system of the moth Manduca sexta.

Sattelle DB, Bai D, Chen HH, Skeer JM, Buckingham SD, Rauh JJ.

Invert Neurosci. 2003 Nov;5(1):37-43. Epub 2003 Nov 8.

PMID:
14608493
45.
46.

Neonicotinoids: insecticides acting on insect nicotinic acetylcholine receptors.

Matsuda K, Buckingham SD, Kleier D, Rauh JJ, Grauso M, Sattelle DB.

Trends Pharmacol Sci. 2001 Nov;22(11):573-80. Review.

PMID:
11698101
47.

Alternative splicing of a Drosophila GABA receptor subunit gene identifies determinants of agonist potency.

Hosie AM, Buckingham SD, Presnail JK, Sattelle DB.

Neuroscience. 2001;102(3):709-14.

PMID:
11226707
48.

K(+) currents in cultured neurones from a polyclad flatworm.

Buckingham SD, Spencer AN.

J Exp Biol. 2000 Oct;203(Pt 20):3189-98.

49.
50.

Antagonist profile and molecular dynamic simulation of a Drosophila melanogaster muscarinic acetylcholine receptor.

Reaper CM, Fanelli F, Buckingham SD, Millar NS, Sattelle DB.

Receptors Channels. 1998;5(6):331-45.

PMID:
9826910

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