Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 275

1.

Coordinated Conformational Processing of the Tumor Suppressor Protein p53 by the Hsp70 and Hsp90 Chaperone Machineries.

Dahiya V, Agam G, Lawatscheck J, Rutz DA, Lamb DC, Buchner J.

Mol Cell. 2019 May 16;74(4):816-830.e7. doi: 10.1016/j.molcel.2019.03.026. Epub 2019 Apr 23.

PMID:
31027879
2.

The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2.

Schopf FH, Huber EM, Dodt C, Lopez A, Biebl MM, Rutz DA, Mühlhofer M, Richter G, Madl T, Sattler M, Groll M, Buchner J.

Mol Cell. 2019 Apr 4;74(1):73-87.e8. doi: 10.1016/j.molcel.2019.02.011. Epub 2019 Mar 12.

PMID:
30876805
3.

Small heat shock proteins: multifaceted proteins with important implications for life.

Carra S, Alberti S, Benesch JLP, Boelens W, Buchner J, Carver JA, Cecconi C, Ecroyd H, Gusev N, Hightower LE, Klevit RE, Lee HO, Liberek K, Lockwood B, Poletti A, Timmerman V, Toth ME, Vierling E, Wu T, Tanguay RM.

Cell Stress Chaperones. 2019 Mar;24(2):295-308. doi: 10.1007/s12192-019-00979-z. Epub 2019 Feb 13. Review.

PMID:
30758704
4.

Structure, Function, and Regulation of the Hsp90 Machinery.

Biebl MM, Buchner J.

Cold Spring Harb Perspect Biol. 2019 Feb 11. pii: a034017. doi: 10.1101/cshperspect.a034017. [Epub ahead of print]

PMID:
30745292
5.

Functional principles and regulation of molecular chaperones.

Dahiya V, Buchner J.

Adv Protein Chem Struct Biol. 2019;114:1-60. doi: 10.1016/bs.apcsb.2018.10.001. Epub 2018 Dec 1.

PMID:
30635079
6.

Molecular chaperones and protein quality control: an introduction to the JBC Reviews thematic series.

Buchner J.

J Biol Chem. 2019 Feb 8;294(6):2074-2075. doi: 10.1074/jbc.REV118.006739. Epub 2019 Jan 9. Review.

7.

The Antibody Light-Chain Linker Regulates Domain Orientation and Amyloidogenicity.

Weber B, Hora M, Kazman P, Göbl C, Camilloni C, Reif B, Buchner J.

J Mol Biol. 2018 Dec 7;430(24):4925-4940. doi: 10.1016/j.jmb.2018.10.024. Epub 2018 Nov 8.

PMID:
30414962
8.

Small heat shock proteins: Simplicity meets complexity.

Haslbeck M, Weinkauf S, Buchner J.

J Biol Chem. 2019 Feb 8;294(6):2121-2132. doi: 10.1074/jbc.REV118.002809. Epub 2018 Oct 31. Review.

9.

Single-molecule force spectroscopy reveals folding steps associated with hormone binding and activation of the glucocorticoid receptor.

Suren T, Rutz D, Mößmer P, Merkel U, Buchner J, Rief M.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):11688-11693. doi: 10.1073/pnas.1807618115. Epub 2018 Oct 26.

10.

A single residue switch reveals principles of antibody domain integrity.

Weber B, Brandl MJ, Pulido Cendales MD, Berner C, Pradhan T, Feind GM, Zacharias M, Reif B, Buchner J.

J Biol Chem. 2018 Nov 2;293(44):17107-17118. doi: 10.1074/jbc.RA118.005475. Epub 2018 Sep 18.

PMID:
30228183
11.

Nucleotide-Dependent Dimer Association and Dissociation of the Chaperone Hsp90.

Tych KM, Jahn M, Gegenfurtner F, Hechtl VK, Buchner J, Hugel T, Rief M.

J Phys Chem B. 2018 Dec 13;122(49):11373-11380. doi: 10.1021/acs.jpcb.8b07301. Epub 2018 Sep 13.

PMID:
30179494
12.

Cytosolic Hsp70 and Hsp40 chaperones enable the biogenesis of mitochondrial β-barrel proteins.

Jores T, Lawatscheck J, Beke V, Franz-Wachtel M, Yunoki K, Fitzgerald JC, Macek B, Endo T, Kalbacher H, Buchner J, Rapaport D.

J Cell Biol. 2018 Sep 3;217(9):3091-3108. doi: 10.1083/jcb.201712029. Epub 2018 Jun 21.

13.

Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD.

Sabbagh JJ, Cordova RA, Zheng D, Criado-Marrero M, Lemus A, Li P, Baker JD, Nordhues BA, Darling AL, Martinez-Licha C, Rutz DA, Patel S, Buchner J, Leahy JW, Koren J 3rd, Dickey CA, Blair LJ.

ACS Chem Biol. 2018 Aug 17;13(8):2288-2299. doi: 10.1021/acschembio.8b00454. Epub 2018 Jun 19.

PMID:
29893552
14.

Concept Inventory Development Reveals Common Student Misconceptions about Microbiology.

Briggs AG, Hughes LE, Brennan RE, Buchner J, Horak REA, Amburn DSK, McDonald AH, Primm TP, Smith AC, Stevens AM, Yung SB, Paustian TD.

J Microbiol Biol Educ. 2017 Oct 30;18(3). pii: 18.3.55. doi: 10.1128/jmbe.v18i3.1319. eCollection 2017.

15.

Development, Validation, and Application of the Microbiology Concept Inventory.

Paustian TD, Briggs AG, Brennan RE, Boury N, Buchner J, Harris S, Horak REA, Hughes LE, Katz-Amburn DS, Massimelli MJ, McDonald AH, Primm TP, Smith AC, Stevens AM, Yung SB.

J Microbiol Biol Educ. 2017 Oct 5;18(3). pii: 18.3.49. doi: 10.1128/jmbe.v18i3.1320. eCollection 2017.

16.

A switch point in the molecular chaperone Hsp90 responding to client interaction.

Rutz DA, Luo Q, Freiburger L, Madl T, Kaila VRI, Sattler M, Buchner J.

Nat Commun. 2018 Apr 16;9(1):1472. doi: 10.1038/s41467-018-03946-x.

17.

Veno-Venous Extracorporeal Membrane Oxygenation for Respiratory Failure: How Long Is Too Long?

Menaker J, Rabinowitz RP, Tabatabai A, Tesoriero RB, Dolly K, Cornachione C, Stene E, Buchner J, Kufera J, Kon ZN, Deatrick KB, Herr DL, O'Connor JV, Scalea TM.

ASAIO J. 2019 Feb;65(2):192-196. doi: 10.1097/MAT.0000000000000791.

PMID:
29608490
18.

Formation and dynamics of a solar eruptive flux tube.

Inoue S, Kusano K, Büchner J, Skála J.

Nat Commun. 2018 Jan 12;9(1):174. doi: 10.1038/s41467-017-02616-8.

19.

Single-Center Experience With Venovenous ECMO for Influenza-Related ARDS.

Buchner J, Mazzeffi M, Kon Z, Menaker J, Rubinson L, Bittle G, Pasrija C, Herr D.

J Cardiothorac Vasc Anesth. 2018 Jun;32(3):1154-1159. doi: 10.1053/j.jvca.2017.09.031. Epub 2017 Sep 22.

PMID:
29325841
20.

Bap (Sil1) regulates the molecular chaperone BiP by coupling release of nucleotide and substrate.

Rosam M, Krader D, Nickels C, Hochmair J, Back KC, Agam G, Barth A, Zeymer C, Hendrix J, Schneider M, Antes I, Reinstein J, Lamb DC, Buchner J.

Nat Struct Mol Biol. 2018 Jan;25(1):90-100. doi: 10.1038/s41594-017-0012-6. Epub 2018 Jan 1.

PMID:
29323281
21.

Folding and Domain Interactions of Three Orthologs of Hsp90 Studied by Single-Molecule Force Spectroscopy.

Jahn M, Tych K, Girstmair H, Steinmaßl M, Hugel T, Buchner J, Rief M.

Structure. 2018 Jan 2;26(1):96-105.e4. doi: 10.1016/j.str.2017.11.023. Epub 2017 Dec 21.

22.

A peptide extension dictates IgM assembly.

Pasalic D, Weber B, Giannone C, Anelli T, Müller R, Fagioli C, Felkl M, John C, Mossuto MF, Becker CFW, Sitia R, Buchner J.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8575-E8584. doi: 10.1073/pnas.1701797114. Epub 2017 Sep 27.

23.

Determinants of the assembly and function of antibody variable domains.

Herold EM, John C, Weber B, Kremser S, Eras J, Berner C, Deubler S, Zacharias M, Buchner J.

Sci Rep. 2017 Sep 25;7(1):12276. doi: 10.1038/s41598-017-12519-9.

24.

The Plasticity of the Hsp90 Co-chaperone System.

Sahasrabudhe P, Rohrberg J, Biebl MM, Rutz DA, Buchner J.

Mol Cell. 2017 Sep 21;67(6):947-961.e5. doi: 10.1016/j.molcel.2017.08.004. Epub 2017 Sep 7.

25.

A chemical compound inhibiting the Aha1-Hsp90 chaperone complex.

Stiegler SC, Rübbelke M, Korotkov VS, Weiwad M, John C, Fischer G, Sieber SA, Sattler M, Buchner J.

J Biol Chem. 2017 Oct 13;292(41):17073-17083. doi: 10.1074/jbc.M117.797829. Epub 2017 Aug 28.

26.

MAK33 antibody light chain amyloid fibrils are similar to oligomeric precursors.

Hora M, Sarkar R, Morris V, Xue K, Prade E, Harding E, Buchner J, Reif B.

PLoS One. 2017 Jul 26;12(7):e0181799. doi: 10.1371/journal.pone.0181799. eCollection 2017.

27.

Using a Concept Inventory to Reveal Student Thinking Associated with Common Misconceptions about Antibiotic Resistance.

Stevens AM, Smith AC, Marbach-Ad G, Balcom SA, Buchner J, Daniel SL, DeStefano JJ, El-Sayed NM, Frauwirth K, Lee VT, McIver KS, Melville SB, Mosser DM, Popham DL, Scharf BE, Schubot FD, Seyler RW Jr, Shields PA, Song W, Stein DC, Stewart RC, Thompson KV, Yang Z, Yarwood SA.

J Microbiol Biol Educ. 2017 Apr 21;18(1). pii: 18.1.10. doi: 10.1128/jmbe.v18i1.1281. eCollection 2017 Apr.

28.

The HSP90 chaperone machinery.

Schopf FH, Biebl MM, Buchner J.

Nat Rev Mol Cell Biol. 2017 Jun;18(6):345-360. doi: 10.1038/nrm.2017.20. Epub 2017 Apr 21. Review.

PMID:
28429788
29.

Remote tele-mentored ultrasound for non-physician learners using FaceTime: A feasibility study in a low-income country.

Robertson TE, Levine AR, Verceles AC, Buchner JA, Lantry JH 3rd, Papali A, Zubrow MT, Colas LN, Augustin ME, McCurdy MT; Haiti Resource Limited Intensive Care (Haiti-RELIC) Study Group.

J Crit Care. 2017 Aug;40:145-148. doi: 10.1016/j.jcrc.2017.03.028. Epub 2017 Apr 7.

PMID:
28402924
30.

ThT 101: a primer on the use of thioflavin T to investigate amyloid formation.

Gade Malmos K, Blancas-Mejia LM, Weber B, Buchner J, Ramirez-Alvarado M, Naiki H, Otzen D.

Amyloid. 2017 Mar;24(1):1-16. doi: 10.1080/13506129.2017.1304905. Epub 2017 Apr 10. Review.

PMID:
28393556
31.

The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells.

Schuster M, Schnell L, Feigl P, Birkhofer C, Mohr K, Roeder M, Carle S, Langer S, Tippel F, Buchner J, Fischer G, Hausch F, Frick M, Schwan C, Aktories K, Schiene-Fischer C, Barth H.

Sci Rep. 2017 Apr 4;7(1):613. doi: 10.1038/s41598-017-00780-x.

32.

The growing world of small heat shock proteins: from structure to functions.

Carra S, Alberti S, Arrigo PA, Benesch JL, Benjamin IJ, Boelens W, Bartelt-Kirbach B, Brundel BJJM, Buchner J, Bukau B, Carver JA, Ecroyd H, Emanuelsson C, Finet S, Golenhofen N, Goloubinoff P, Gusev N, Haslbeck M, Hightower LE, Kampinga HH, Klevit RE, Liberek K, Mchaourab HS, McMenimen KA, Poletti A, Quinlan R, Strelkov SV, Toth ME, Vierling E, Tanguay RM.

Cell Stress Chaperones. 2017 Jul;22(4):601-611. doi: 10.1007/s12192-017-0787-8. Epub 2017 Mar 31. Review.

33.

Hsp90 dependence of a kinase is determined by its conformational landscape.

Luo Q, Boczek EE, Wang Q, Buchner J, Kaila VR.

Sci Rep. 2017 Mar 14;7:43996. doi: 10.1038/srep43996.

34.

An alternative splice variant of human αA-crystallin modulates the oligomer ensemble and the chaperone activity of α-crystallins.

Preis W, Bestehorn A, Buchner J, Haslbeck M.

Cell Stress Chaperones. 2017 Jul;22(4):541-552. doi: 10.1007/s12192-017-0772-2. Epub 2017 Feb 18.

35.

Epigallocatechin-3-gallate preferentially induces aggregation of amyloidogenic immunoglobulin light chains.

Hora M, Carballo-Pacheco M, Weber B, Morris VK, Wittkopf A, Buchner J, Strodel B, Reif B.

Sci Rep. 2017 Jan 27;7:41515. doi: 10.1038/srep41515.

36.

Solid- and solution-state nuclear magnetic resonance spectroscopic studies on antibody light chain amyloid formation and interactions with epigallocatechin gallate.

Hora M, Carballo Pacheco M, Weber B, Buchner J, Strodel B, Reif B.

Amyloid. 2017 Mar;24(sup1):10. doi: 10.1080/13506129.2016.1269736. Epub 2016 Dec 26. No abstract available.

PMID:
28019720
37.

In memoriam-Rainer Jaenicke.

Buchner J, Eisenberg D, Schmid F.

Protein Sci. 2017 Mar;26(3):394-395. doi: 10.1002/pro.3098. Epub 2017 Feb 13. No abstract available.

38.

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins.

Mymrikov EV, Daake M, Richter B, Haslbeck M, Buchner J.

J Biol Chem. 2017 Jan 13;292(2):672-684. doi: 10.1074/jbc.M116.760413. Epub 2016 Nov 30.

39.

Importance of cycle timing for the function of the molecular chaperone Hsp90.

Zierer BK, Rübbelke M, Tippel F, Madl T, Schopf FH, Rutz DA, Richter K, Sattler M, Buchner J.

Nat Struct Mol Biol. 2016 Nov;23(11):1020-1028. doi: 10.1038/nsmb.3305. Epub 2016 Oct 10.

40.

Allosteric Regulation Points Control the Conformational Dynamics of the Molecular Chaperone Hsp90.

Rehn A, Moroni E, Zierer BK, Tippel F, Morra G, John C, Richter K, Colombo G, Buchner J.

J Mol Biol. 2016 Nov 6;428(22):4559-4571. doi: 10.1016/j.jmb.2016.09.014. Epub 2016 Sep 20.

PMID:
27663270
41.

Oxidation in the complementarity-determining regions differentially influences the properties of therapeutic antibodies.

Dashivets T, Stracke J, Dengl S, Knaupp A, Pollmann J, Buchner J, Schlothauer T.

MAbs. 2016 Nov/Dec;8(8):1525-1535. Epub 2016 Sep 9.

42.

Cross-Linking GPVI-Fc by Anti-Fc Antibodies Potentiates Its Inhibition of Atherosclerotic Plaque- and Collagen-Induced Platelet Activation.

Jamasbi J, Megens RT, Bianchini M, Uhland K, Münch G, Ungerer M, Sherman S, Faussner A, Brandl R, John C, Buchner J, Weber C, Lorenz R, Elia N, Siess W.

JACC Basic Transl Sci. 2016 Apr 25;1(3):131-142.. eCollection 2016 Apr. Review.

43.

The cytosolic cochaperone Sti1 is relevant for mitochondrial biogenesis and morphology.

Hoseini H, Pandey S, Jores T, Schmitt A, Franz-Wachtel M, Macek B, Buchner J, Dimmer KS, Rapaport D.

FEBS J. 2016 Sep;283(18):3338-52. doi: 10.1111/febs.13813. Epub 2016 Jul 28.

44.

BiPPred: Combined sequence- and structure-based prediction of peptide binding to the Hsp70 chaperone BiP.

Schneider M, Rosam M, Glaser M, Patronov A, Shah H, Back KC, Daake MA, Buchner J, Antes I.

Proteins. 2016 Oct;84(10):1390-407. doi: 10.1002/prot.25084. Epub 2016 Jul 13.

PMID:
27287023
45.

Ultrasound images transmitted via FaceTime are non-inferior to images on the ultrasound machine.

Levine AR, Buchner JA, Verceles AC, Zubrow MT, Mallemat HA, Papali A, McCurdy MT.

J Crit Care. 2016 Jun;33:51-5. doi: 10.1016/j.jcrc.2016.02.019. Epub 2016 Feb 28.

PMID:
27006267
46.

A Stable Mutant Predisposes Antibody Domains to Amyloid Formation through Specific Non-Native Interactions.

Nokwe CN, Hora M, Zacharias M, Yagi H, Peschek J, Reif B, Goto Y, Buchner J.

J Mol Biol. 2016 Mar 27;428(6):1315-1332. doi: 10.1016/j.jmb.2016.01.015. Epub 2016 Jan 29.

PMID:
26827727
47.

Folding and assembly of the large molecular machine Hsp90 studied in single-molecule experiments.

Jahn M, Buchner J, Hugel T, Rief M.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1232-7. doi: 10.1073/pnas.1518827113. Epub 2016 Jan 19.

48.

Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants.

Dashivets T, Thomann M, Rueger P, Knaupp A, Buchner J, Schlothauer T.

PLoS One. 2015 Dec 11;10(12):e0143520. doi: 10.1371/journal.pone.0143520. eCollection 2015.

49.

The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client.

Mainz A, Peschek J, Stavropoulou M, Back KC, Bardiaux B, Asami S, Prade E, Peters C, Weinkauf S, Buchner J, Reif B.

Nat Struct Mol Biol. 2015 Nov;22(11):898-905. doi: 10.1038/nsmb.3108. Epub 2015 Oct 12.

50.

The Antibody Light-Chain Linker Is Important for Domain Stability and Amyloid Formation.

Nokwe CN, Hora M, Zacharias M, Yagi H, John C, Reif B, Goto Y, Buchner J.

J Mol Biol. 2015 Nov 6;427(22):3572-3586. doi: 10.1016/j.jmb.2015.09.012. Epub 2015 Sep 25.

PMID:
26408269

Supplemental Content

Loading ...
Support Center