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Items: 1 to 50 of 60

1.

Transgenic expression of human INS gene in Ins1/Ins2 double knockout mice leads to insulin underproduction and diabetes in some male mice.

Karaca M, Durel B, Languille L, Lamotte L, Tourrel-Cuzin C, Leroux L, Abou Sleymane G, Saint-Just S, Bucchini D, Ktorza A, Joshi RL.

Front Biosci. 2007 Jan 1;12:1586-93.

PMID:
17127405
2.

Knock-in of diphteria toxin A chain gene at Ins2 locus: effects on islet development and localization of Ins2 expression in the brain.

Lamotte L, Jackerott M, Bucchini D, Jami J, Joshi RL, Deltour L.

Transgenic Res. 2004 Oct;13(5):463-73.

PMID:
15587270
3.

Ins1 gene up-regulated in a beta-cell line derived from Ins2 knockout mice.

Leroux L, Durel B, Autier V, Deltour L, Bucchini D, Jami J, Joshi RL.

Int J Exp Diabesity Res. 2003 Jan-Mar;4(1):7-12.

4.

Improved metabolic disorders of insulin receptor-deficient mice by transgenic overexpression of glucokinase in the liver.

Jackerott M, Baudry A, Bucchini D, Jami J, Joshi RL.

Diabetologia. 2002 Sep;45(9):1292-7. Epub 2002 Jul 31.

PMID:
12242462
5.

Overexpression of the V3 vasopressin receptor in transgenic mice corticotropes leads to increased basal corticosterone.

René P, Grino M, Viollet C, Videau C, Jullian E, Bucchini D, Epelbaum J, Bertagna X, de Keyzer Y.

J Neuroendocrinol. 2002 Sep;14(9):737-44.

PMID:
12213135
6.

Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin.

Duvillié B, Currie C, Chrones T, Bucchini D, Jami J, Joshi RL, Hill DJ.

Endocrinology. 2002 Apr;143(4):1530-7.

PMID:
11897712
7.

Compensatory responses in mice carrying a null mutation for Ins1 or Ins2.

Leroux L, Desbois P, Lamotte L, Duvillié B, Cordonnier N, Jackerott M, Jami J, Bucchini D, Joshi RL.

Diabetes. 2001 Feb;50 Suppl 1:S150-3.

8.

Endocrine pancreas in insulin receptor-deficient mouse pups.

Jackerott M, Baudry A, Lamothe B, Bucchini D, Jami J, Joshi RL.

Diabetes. 2001 Feb;50 Suppl 1:S146-9.

9.

Expression of a V region-less B cell receptor confers a tolerance-like phenotype on transgenic B cells.

Corcos D, Grandien A, Vazquez A, Dunda O, Lorès P, Bucchini D.

J Immunol. 2001 Mar 1;166(5):3083-9.

10.

IGF-1 receptor as an alternative receptor for metabolic signaling in insulin receptor-deficient muscle cells.

Baudry A, Lamothe B, Bucchini D, Jami J, Montarras D, Pinset C, Joshi RL.

FEBS Lett. 2001 Jan 19;488(3):174-8.

11.

[Insulin and its receptor: lessons learned from the disruption of their gene in mice].

Baudry A, Bucchini D, Deltour L, Desbois P, Durel B, Duvillié B, Jackerott M, Jami J, Joshi RL, Lamothe B, Lamotte L, Cordonnier-Lefort N, Leroux L, Saint Just S.

Journ Annu Diabetol Hotel Dieu. 1999:105-13. French. No abstract available.

PMID:
10732410
12.

Transgenic expression of Fas ligand on thyroid follicular cells prevents autoimmune thyroiditis.

Batteux F, Lores P, Bucchini D, Chiocchia G.

J Immunol. 2000 Feb 15;164(4):1681-8.

13.

Early embryonic lethality of H ferritin gene deletion in mice.

Ferreira C, Bucchini D, Martin ME, Levi S, Arosio P, Grandchamp B, Beaumont C.

J Biol Chem. 2000 Feb 4;275(5):3021-4.

14.

Human insulin gene insertion in mice. Effects on the sleep-wake cycle?

Valatx JL, Douhet P, Bucchini D.

J Sleep Res. 1999 Jun;8 Suppl 1:65-8.

15.

Expression of human F8B, a gene nested within the coagulation factor VIII gene, produces multiple eye defects and developmental alterations in chimeric and transgenic mice.

Valleix S, Jeanny JC, Elsevier S, Joshi RL, Fayet P, Bucchini D, Delpech M.

Hum Mol Genet. 1999 Jul;8(7):1291-301.

PMID:
10369875
16.

Genetic engineering in mice: impact on insulin signalling and action.

Lamothe B, Baudry A, Desbois P, Lamotte L, Bucchini D, De Meyts P, Joshi RL.

Biochem J. 1998 Oct 15;335 ( Pt 2):193-204. Review.

17.

Differential roles of upstream stimulatory factors 1 and 2 in the transcriptional response of liver genes to glucose.

Vallet VS, Casado M, Henrion AA, Bucchini D, Raymondjean M, Kahn A, Vaulont S.

J Biol Chem. 1998 Aug 7;273(32):20175-9.

18.

Insulin and insulin-like growth factor-I receptor mediated differentiation of 3T3-F442A cells into adipocytes: effect of PI 3-kinase inhibition.

Christoffersen CT, Tornqvist H, Vlahos CJ, Bucchini D, Jami J, De Meyts P, Joshi RL.

Biochem Biophys Res Commun. 1998 May 19;246(2):426-30.

PMID:
9610377
19.

Genetic manipulation of insulin action and beta-cell function in mice.

Lamothe B, Duvillié B, Cordonnier N, Baudry A, Saint-Just S, Bucchini D, Jami J, Joshi RL.

Mol Cell Biochem. 1998 May;182(1-2):161-8.

PMID:
9609125
20.

Insulin receptor-deficient cells as a new tool for dissecting complex interplay in insulin and insulin-like growth factors.

Lamothe B, Baudry A, Christoffersen CT, De Meyts P, Jami J, Bucchini D, Joshi RL.

FEBS Lett. 1998 Apr 24;426(3):381-5.

21.

Imprinting at the mouse Ins2 locus: evidence for cis- and trans-allelic interactions.

Duvillié B, Bucchini D, Tang T, Jami J, Pàldi A.

Genomics. 1998 Jan 1;47(1):52-7.

PMID:
9465295
22.

Glucose-dependent liver gene expression in upstream stimulatory factor 2 -/- mice.

Vallet VS, Henrion AA, Bucchini D, Casado M, Raymondjean M, Kahn A, Vaulont S.

J Biol Chem. 1997 Aug 29;272(35):21944-9.

23.

Phenotypic alterations in insulin-deficient mutant mice.

Duvillié B, Cordonnier N, Deltour L, Dandoy-Dron F, Itier JM, Monthioux E, Jami J, Joshi RL, Bucchini D.

Proc Natl Acad Sci U S A. 1997 May 13;94(10):5137-40.

24.

Genetically engineered mice as animal models for NIDDM.

Joshi RL, Lamothe B, Bucchini D, Jami J.

FEBS Lett. 1997 Jan 20;401(2-3):99-103. Review.

25.
26.

Human insulin gene expression in transgenic mice: mutational analysis of the regulatory region.

Itier JM, Douhet P, Desbois P, Joshi RL, Dandoy-Dron F, Jami J, Bucchini D.

Differentiation. 1996 Sep;60(5):309-16.

PMID:
8855374
27.

Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality.

Joshi RL, Lamothe B, Cordonnier N, Mesbah K, Monthioux E, Jami J, Bucchini D.

EMBO J. 1996 Apr 1;15(7):1542-7.

28.
29.

Pre-B-cell development in the absence of lambda 5 in transgenic mice expressing a heavy-chain disease protein.

Corcos D, Dunda O, Butor C, Cesbron JY, Lorès P, Bucchini D, Jami J.

Curr Biol. 1995 Oct 1;5(10):1140-8.

30.

Tissue-specific expression of the rat insulin 1 gene in vivo requires both the enhancer and promoter regions.

Dandoy-Dron F, Itier JM, Monthioux E, Bucchini D, Jami J.

Differentiation. 1995 Apr;58(4):291-5.

PMID:
7641979
31.

Expression of a human insulin transgene in cholinergic neurons of the mouse medial habenula.

Douhet P, Destrade C, Bucchini D, Calas A.

Biol Cell. 1995;85(2-3):137-46.

PMID:
8785515
32.

The potential immunogenicity of human insulin and insulin analogues evaluated in a transgenic mouse model.

Ottesen JL, Nilsson P, Jami J, Weilguny D, Dührkop M, Bucchini D, Havelund S, Fogh JM.

Diabetologia. 1994 Dec;37(12):1178-85.

PMID:
7895946
33.

Promoter, enhancer and silencer elements regulate rearrangement of an immunoglobulin transgene.

Lauster R, Reynaud CA, Mårtensson IL, Peter A, Bucchini D, Jami J, Weill JC.

EMBO J. 1993 Dec;12(12):4615-23.

34.

Differential expression of non-allelic insulin genes in rodent islet tumour cells.

Lund K, Blume N, Michelsen BK, Bucchini D, Madsen OD.

J Mol Endocrinol. 1993 Dec;11(3):305-18.

PMID:
8148038
35.

Insulin gene can be expressed in the absence of Isl-1.

Dandoy-Dron F, Deltour L, Monthioux E, Bucchini D, Jami J.

Exp Cell Res. 1993 Nov;209(1):58-63.

PMID:
8224007
36.

Differential expression of the two nonallelic proinsulin genes in the developing mouse embryo.

Deltour L, Leduque P, Blume N, Madsen O, Dubois P, Jami J, Bucchini D.

Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):527-31.

37.
38.

Allelic exclusion in transgenic mice expressing a heavy chain disease-like human mu protein.

Corcos D, Iglesias A, Dunda O, Bucchini D, Jami J.

Eur J Immunol. 1991 Nov;21(11):2711-6.

PMID:
1936120
39.

Regulatory regions of rat insulin I gene necessary for expression in transgenic mice.

Dandoy-Dron F, Monthioux E, Jami J, Bucchini D.

Nucleic Acids Res. 1991 Sep 25;19(18):4925-30.

40.

Effect of 5'-flanking sequence deletions on expression of the human insulin gene in transgenic mice.

Fromont-Racine M, Bucchini D, Madsen O, Desbois P, Linde S, Nielsen JH, Saulnier C, Ripoche MA, Jami J, Pictet R.

Mol Endocrinol. 1990 May;4(5):669-77.

PMID:
2274051
41.

B islet cells of pancreas are the site of expression of the human insulin gene in transgenic mice.

Bucchini D, Madsen O, Desbois P, Pictet R, Jami J.

Exp Cell Res. 1989 Feb;180(2):467-74.

PMID:
2644126
42.

Expression of human insulin and hybrid insulin genes in pancreatic beta cells of transgenic mice.

Bucchini D, Deltour L, Jami J.

Horm Res. 1989;32(1-3):47-52. Review.

PMID:
2693315
43.

Chromosome localization of the human insulin gene in transgenic mouse lines.

Michalova K, Bucchini D, Ripoche MA, Pictet R, Jami J.

Hum Genet. 1988 Nov;80(3):247-52.

PMID:
3056832
44.

Human insulin gene in transgenic mouse lines.

Fromont-Racine M, Bucchini D, Desbois P, Pictet R, Jami J.

Biomed Biochim Acta. 1988;47(4-5):349-53.

PMID:
3071363
45.

Rearrangement of a chicken immunoglobulin gene occurs in the lymphoid lineage of transgenic mice.

Bucchini D, Reynaud CA, Ripoche MA, Grimal H, Jami J, Weill JC.

Nature. 1987 Mar 26-Apr 1;326(6111):409-11.

PMID:
3031506
46.

Pancreatic expression of human insulin gene in transgenic mice.

Bucchini D, Ripoche MA, Stinnakre MG, Desbois P, Lorès P, Monthioux E, Absil J, Lepesant JA, Pictet R, Jami J.

Proc Natl Acad Sci U S A. 1986 Apr;83(8):2511-5.

47.

Differential expression of two linked selection genes (HSVI-tk and Eco.gpt) in transformed teratocarcinoma and in L cells.

Lasserre C, Thillet J, Besnard C, Bucchini D, Pictet R, Jami J.

J Cell Physiol. 1985 Jul;124(1):37-42.

PMID:
2995411
48.

Altered structure of HLA class I heavy chains associated with mouse beta-2 microglobulin.

Ferrier P, Fontecilla-Camps JC, Bucchini D, Caillol DH, Jordan BR, Lemonnier FA.

Immunogenetics. 1985;21(4):321-31.

PMID:
2581890
49.

Transformation of teratocarcinoma stem cells and fibroblasts with various vectors containing the Eco.gpt gene as a selection marker.

Thillet J, Kunst F, Lasserre C, Bucchini D, Pictet R, Jami J.

Exp Cell Res. 1984 Apr;151(2):494-501.

PMID:
6323202
50.

"Endless" viral DNA in cells infected with channel catfish virus.

Cebrian J, Bucchini D, Sheldrick P.

J Virol. 1983 May;46(2):405-12.

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