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Chemokine receptors in advanced breast cancer: differential expression in metastatic disease sites with diagnostic and therapeutic implications.

Cabioglu N, Sahin AA, Morandi P, Meric-Bernstam F, Islam R, Lin HY, Bucana CD, Gonzalez-Angulo AM, Hortobagyi GN, Cristofanilli M.

Ann Oncol. 2009 Jun;20(6):1013-9. doi: 10.1093/annonc/mdn740. Epub 2009 Feb 23.


Platelet-derived growth factor receptor inhibition and chemotherapy for castration-resistant prostate cancer with bone metastases.

Mathew P, Thall PF, Bucana CD, Oh WK, Morris MJ, Jones DM, Johnson MM, Wen S, Pagliaro LC, Tannir NM, Tu SM, Meluch AA, Smith L, Cohen L, Kim SJ, Troncoso P, Fidler IJ, Logothetis CJ.

Clin Cancer Res. 2007 Oct 1;13(19):5816-24.


Targeting of insulin-like growth factor-I receptor with a monoclonal antibody inhibits growth of hepatic metastases from human colon carcinoma in mice.

Bauer TW, Fan F, Liu W, Camp ER, Yang A, Somcio RJ, Bucana CD, Singh R, Ellis LM.

Ann Surg Oncol. 2007 Oct;14(10):2838-46. Epub 2007 Jul 26.


Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice.

Itasaka S, Komaki R, Herbst RS, Shibuya K, Shintani T, Hunter NR, Onn A, Bucana CD, Milas L, Ang KK, O'Reilly MS.

Int J Radiat Oncol Biol Phys. 2007 Mar 1;67(3):870-8.


mda-7 In combination with bevacizumab treatment produces a synergistic and complete inhibitory effect on lung tumor xenograft.

Inoue S, Hartman A, Branch CD, Bucana CD, Bekele BN, Stephens LC, Chada S, Ramesh R.

Mol Ther. 2007 Feb;15(2):287-94.


Effects of the integrin-linked kinase inhibitor QLT0267 on squamous cell carcinoma of the head and neck.

Younes MN, Yigitbasi OG, Yazici YD, Jasser SA, Bucana CD, El-Naggar AK, Mills GB, Myers JN.

Arch Otolaryngol Head Neck Surg. 2007 Jan;133(1):15-23.


Pathogenesis and vascular integrity of breast cancer brain metastasis.

Lu W, Bucana CD, Schroit AJ.

Int J Cancer. 2007 Mar 1;120(5):1023-6.


Expression of activated platelet-derived growth factor receptor in stromal cells of human colon carcinomas is associated with metastatic potential.

Kitadai Y, Sasaki T, Kuwai T, Nakamura T, Bucana CD, Hamilton SR, Fidler IJ.

Int J Cancer. 2006 Dec 1;119(11):2567-74.


Growth-inhibitory effects of human anti-insulin-like growth factor-I receptor antibody (A12) in an orthotopic nude mouse model of anaplastic thyroid carcinoma.

Wang Z, Chakravarty G, Kim S, Yazici YD, Younes MN, Jasser SA, Santillan AA, Bucana CD, El-Naggar AK, Myers JN.

Clin Cancer Res. 2006 Aug 1;12(15):4755-65.


Antivascular therapy of oral tongue squamous cell carcinoma with PTK787.

Yazici YD, Kim S, Jasser SA, Wang Z, Carter KB Jr, Bucana CD, Myers JN.

Laryngoscope. 2005 Dec;115(12):2249-55.


Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice.

Bauer TW, Liu W, Fan F, Camp ER, Yang A, Somcio RJ, Bucana CD, Callahan J, Parry GC, Evans DB, Boyd DD, Mazar AP, Ellis LM.

Cancer Res. 2005 Sep 1;65(17):7775-81.


Antivascular therapy of human follicular thyroid cancer experimental bone metastasis by blockade of epidermal growth factor receptor and vascular growth factor receptor phosphorylation.

Younes MN, Yigitbasi OG, Park YW, Kim SJ, Jasser SA, Hawthorne VS, Yazici YD, Mandal M, Bekele BN, Bucana CD, Fidler IJ, Myers JN.

Cancer Res. 2005 Jun 1;65(11):4716-27.


AEE788, a dual tyrosine kinase receptor inhibitor, induces endothelial cell apoptosis in human cutaneous squamous cell carcinoma xenografts in nude mice.

Park YW, Younes MN, Jasser SA, Yigitbasi OG, Zhou G, Bucana CD, Bekele BN, Myers JN.

Clin Cancer Res. 2005 Mar 1;11(5):1963-73.


Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage.

Uehara H, Troncoso P, Johnston D, Bucana CD, Dinney C, Dong Z, Fidler IJ, Pettaway CA.

Prostate. 2005 Jun 15;64(1):40-9.


Tumor cell and endothelial cell therapy of oral cancer by dual tyrosine kinase receptor blockade.

Yigitbasi OG, Younes MN, Doan D, Jasser SA, Schiff BA, Bucana CD, Bekele BN, Fidler IJ, Myers JN.

Cancer Res. 2004 Nov 1;64(21):7977-84.


Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation.

Stoeltzing O, McCarty MF, Wey JS, Fan F, Liu W, Belcheva A, Bucana CD, Semenza GL, Ellis LM.

J Natl Cancer Inst. 2004 Jun 16;96(12):946-56.


Neuropilin-1 in human colon cancer: expression, regulation, and role in induction of angiogenesis.

Parikh AA, Fan F, Liu WB, Ahmad SA, Stoeltzing O, Reinmuth N, Bielenberg D, Bucana CD, Klagsbrun M, Ellis LM.

Am J Pathol. 2004 Jun;164(6):2139-51.


Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer.

Onn A, Correa AM, Gilcrease M, Isobe T, Massarelli E, Bucana CD, O'Reilly MS, Hong WK, Fidler IJ, Putnam JB, Herbst RS.

Clin Cancer Res. 2004 Jan 1;10(1 Pt 1):136-43.


E1A gene therapy inhibits angiogenesis in a Ewing's sarcoma animal model.

Zhou Z, Zhou RR, Guan H, Bucana CD, Kleinerman ES.

Mol Cancer Ther. 2003 Dec;2(12):1313-9.


Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer.

Stoeltzing O, Liu W, Reinmuth N, Fan F, Parikh AA, Bucana CD, Evans DB, Semenza GL, Ellis LM.

Am J Pathol. 2003 Sep;163(3):1001-11.


Epidermal growth factor receptor blockade potentiates apoptosis mediated by Paclitaxel and leads to prolonged survival in a murine model of oral cancer.

Holsinger FC, Doan DD, Jasser SA, Swan EA, Greenberg JS, Schiff BA, Bekele BN, Younes MN, Bucana CD, Fidler IJ, Myers JN.

Clin Cancer Res. 2003 Aug 1;9(8):3183-9.


Expression and regulation of the novel vascular endothelial growth factor receptor neuropilin-1 by epidermal growth factor in human pancreatic carcinoma.

Parikh AA, Liu WB, Fan F, Stoeltzing O, Reinmuth N, Bruns CJ, Bucana CD, Evans DB, Ellis LM.

Cancer. 2003 Aug 15;98(4):720-9.


Epidermal hyperplasia overlying human melanoma correlates with tumour depth and angiogenesis.

McCarty MF, Bielenberg DR, Nilsson MB, Gershenwald JE, Barnhill RL, Ahearne P, Bucana CD, Fidler IJ.

Melanoma Res. 2003 Aug;13(4):379-87.


Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors.

Stoeltzing O, Ahmad SA, Liu W, McCarty MF, Wey JS, Parikh AA, Fan F, Reinmuth N, Kawaguchi M, Bucana CD, Ellis LM.

Cancer Res. 2003 Jun 15;63(12):3370-7.


Alphavbeta3 integrin antagonist S247 decreases colon cancer metastasis and angiogenesis and improves survival in mice.

Reinmuth N, Liu W, Ahmad SA, Fan F, Stoeltzing O, Parikh AA, Bucana CD, Gallick GE, Nickols MA, Westlin WF, Ellis LM.

Cancer Res. 2003 May 1;63(9):2079-87.


Active specific immunotherapy against occult brain metastasis.

Lu W, Su J, Kim LS, Bucana CD, Donawho C, He J, Fidler IJ, Dong Z.

Cancer Res. 2003 Mar 15;63(6):1345-50.


Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells.

Akagi M, Kawaguchi M, Liu W, McCarty MF, Takeda A, Fan F, Stoeltzing O, Parikh AA, Jung YD, Bucana CD, Mansfield PF, Hicklin DJ, Ellis LM.

Br J Cancer. 2003 Mar 10;88(5):796-802.


Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice.

Stoeltzing O, Liu W, Reinmuth N, Fan F, Parry GC, Parikh AA, McCarty MF, Bucana CD, Mazar AP, Ellis LM.

Int J Cancer. 2003 Apr 20;104(4):496-503.


Targeted therapy against human lung cancer in nude mice by high-affinity recombinant antimesothelin single-chain Fv immunotoxin.

Fan D, Yano S, Shinohara H, Solorzano C, Van Arsdall M, Bucana CD, Pathak S, Kruzel E, Herbst RS, Onn A, Roach JS, Onda M, Wang QC, Pastan I, Fidler IJ.

Mol Cancer Ther. 2002 Jun;1(8):595-600.


Multiparametric in situ mRNA hybridization analysis of gastric biopsies predicts lymph node metastasis in patients with gastric carcinoma.

Takahashi Y, Kitadai Y, Ellis LM, Bucana CD, Fidler IJ, Mai M.

Jpn J Cancer Res. 2002 Nov;93(11):1258-65.


Angiopoietin-1 inhibits tumour growth and ascites formation in a murine model of peritoneal carcinomatosis.

Stoeltzing O, Ahmad SA, Liu W, McCarty MF, Parikh AA, Fan F, Reinmuth N, Bucana CD, Ellis LM.

Br J Cancer. 2002 Nov 4;87(10):1182-7.


Impact of insulin-like growth factor receptor-I function on angiogenesis, growth, and metastasis of colon cancer.

Reinmuth N, Fan F, Liu W, Parikh AA, Stoeltzing O, Jung YD, Bucana CD, Radinsky R, Gallick GE, Ellis LM.

Lab Invest. 2002 Oct;82(10):1377-89.


Blockade of insulin-like growth factor I receptor function inhibits growth and angiogenesis of colon cancer.

Reinmuth N, Liu W, Fan F, Jung YD, Ahmad SA, Stoeltzing O, Bucana CD, Radinsky R, Ellis LM.

Clin Cancer Res. 2002 Oct;8(10):3259-69.


Characterization of 11 human sarcoma cell strains: evaluation of cytogenetics, tumorigenicity, metastasis, and production of angiogenic factors.

Hu M, Nicolson GL, Trent JC 2nd, Yu D, Zhang L, Lang A, Killary A, Ellis LM, Bucana CD, Pollock RE.

Cancer. 2002 Oct 1;95(7):1569-76.


Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion.

Harmey JH, Bucana CD, Lu W, Byrne AM, McDonnell S, Lynch C, Bouchier-Hayes D, Dong Z.

Int J Cancer. 2002 Oct 10;101(5):415-22.


Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas.

Baker CH, Kedar D, McCarty MF, Tsan R, Weber KL, Bucana CD, Fidler IJ.

Am J Pathol. 2002 Sep;161(3):929-38.


Quantitative and qualitative in vivo angiogenesis assay.

McCarty MF, Baker CH, Bucana CD, Fidler IJ.

Int J Oncol. 2002 Jul;21(1):5-10.


Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells.

Davies MA, Kim SJ, Parikh NU, Dong Z, Bucana CD, Gallick GE.

Clin Cancer Res. 2002 Jun;8(6):1904-14.


Effects of combination anti-vascular endothelial growth factor receptor and anti-epidermal growth factor receptor therapies on the growth of gastric cancer in a nude mouse model.

Jung YD, Mansfield PF, Akagi M, Takeda A, Liu W, Bucana CD, Hicklin DJ, Ellis LM.

Eur J Cancer. 2002 May;38(8):1133-40.


Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells.

Huang S, Bucana CD, Van Arsdall M, Fidler IJ.

Oncogene. 2002 Apr 11;21(16):2504-12.

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