Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 539

1.

Genotyping Two Promoter Polymorphisms in the MIF Gene: A -794 CATT5-8 Microsatellite Repeat and a -173 G/C SNP.

Leng L, Siu E, Bucala R.

Methods Mol Biol. 2020;2080:67-84. doi: 10.1007/978-1-4939-9936-1_7.

PMID:
31745872
2.

Macrophage migration inhibitory factor promoter polymorphisms are associated with disease activity in rheumatoid arthritis patients from Southern Mexico.

Santoscoy-Ascencio G, Baños-Hernández CJ, Navarro-Zarza JE, Hernández-Bello J, Bucala R, López-Quintero A, Valdés-Alvarado E, Parra-Rojas I, Illades-Aguiar B, Muñoz-Valle JF.

Mol Genet Genomic Med. 2019 Nov 7:e1037. doi: 10.1002/mgg3.1037. [Epub ahead of print]

3.

MiRNA Regulation of MIF in SLE and Attenuation of Murine Lupus Nephritis With miR-654.

Tu Y, Guo R, Li J, Wang S, Leng L, Deng J, Bucala R, Lu L.

Front Immunol. 2019 Sep 19;10:2229. doi: 10.3389/fimmu.2019.02229. eCollection 2019.

4.

A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity.

Tilstam PV, Pantouris G, Corman M, Andreoli M, Mahboubi K, Davis G, Du X, Leng L, Lolis E, Bucala R.

J Biol Chem. 2019 Dec 6;294(49):18522-18531. doi: 10.1074/jbc.RA119.009860. Epub 2019 Oct 2.

5.

The small molecule macrophage migration inhibitory factor antagonist MIF098, inhibits pulmonary hypertension associated with murine SLE.

Huang H, Chen D, Pu J, Yuan A, Fu Q, Li J, Leng L, Bucala R, Ye S, Lu L.

Int Immunopharmacol. 2019 Nov;76:105874. doi: 10.1016/j.intimp.2019.105874. Epub 2019 Sep 6.

PMID:
31499270
6.

Cardiomyocyte d-dopachrome tautomerase protects against heart failure.

Ma Y, Su KN, Pfau D, Rao VS, Wu X, Hu X, Leng L, Du X, Piecychna M, Bedi K, Campbell SG, Eichmann A, Testani JM, Margulies KB, Bucala R, Young LH.

JCI Insight. 2019 Sep 5;4(17). pii: 128900. doi: 10.1172/jci.insight.128900.

7.

Macrophage migration inhibitory factor (MIF) as a therapeutic target for rheumatoid arthritis and systemic lupus erythematosus.

Bilsborrow JB, Doherty E, Tilstam PV, Bucala R.

Expert Opin Ther Targets. 2019 Sep;23(9):733-744. doi: 10.1080/14728222.2019.1656718. Epub 2019 Aug 20.

PMID:
31414920
8.

Macrophage migration inhibitory factor enhances influenza-associated mortality in mice.

Smith CA, Tyrell DJ, Kulkarni UA, Wood S, Leng L, Zemans RL, Bucala R, Goldstein DR.

JCI Insight. 2019 Jul 11;4(13). pii: 128034. doi: 10.1172/jci.insight.128034. eCollection 2019 Jul 11.

9.

MIF mediates bladder pain, not inflammation, in cyclophosphamide cystitis.

Ma F, Kouzoukas DE, Meyer-Siegler KL, Hunt DE, Leng L, Bucala R, Vera PL.

Cytokine X. 2019 Mar;1(1). pii: 100003. doi: 10.1016/j.cytox.2019.100003. Epub 2019 Jan 23.

10.

The immunobiology of MIF: function, genetics and prospects for precision medicine.

Kang I, Bucala R.

Nat Rev Rheumatol. 2019 Jul;15(7):427-437. doi: 10.1038/s41584-019-0238-2. Epub 2019 Jun 13. Review.

PMID:
31197253
11.

CD74 knockout attenuates alcohol intake-induced cardiac dysfunction through AMPK-Skp2-mediated regulation of autophagy.

Yang L, Wang S, Ma J, Li J, Yang J, Bucala R, Ren J.

Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2368-2378. doi: 10.1016/j.bbadis.2019.05.020. Epub 2019 Jun 2.

PMID:
31167126
12.

Novel Role of Macrophage Migration Inhibitory Factor in Upstream Control of the Unfolded Protein Response After Ethanol Feeding in Mice.

Poulsen KL, McMullen MR, Huang E, Kibler CD, Sheehan MM, Leng L, Bucala R, Nagy LE.

Alcohol Clin Exp Res. 2019 Jul;43(7):1439-1451. doi: 10.1111/acer.14065. Epub 2019 May 14.

PMID:
31009094
13.

Trust in Publication: Now More Than Ever.

Bucala RJ, Solomon DH.

Arthritis Rheumatol. 2019 Oct;71(10):1593-1594. doi: 10.1002/art.40882. Epub 2019 Aug 4. No abstract available.

PMID:
30860662
14.

Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine.

Scholzen A, Richard G, Moise L, Baeten LA, Reeves PM, Martin WD, Brauns TA, Boyle CM, Raju Paul S, Bucala R, Bowen RA, Garritsen A, De Groot AS, Sluder AE, Poznansky MC.

Front Immunol. 2019 Feb 15;10:207. doi: 10.3389/fimmu.2019.00207. eCollection 2019.

15.

Macrophage migration inhibitory factor regulates innate γδ T-cell responses via IL-17 expression.

Kim HK, Garcia AB, Siu E, Tilstam P, Das R, Roberts S, Leng L, Bucala R.

FASEB J. 2019 Jun;33(6):6919-6932. doi: 10.1096/fj.201802433R. Epub 2019 Feb 28.

PMID:
30817226
16.

miR-152 Attenuates the Severity of Lupus Nephritis Through the Downregulation of Macrophage Migration Inhibitory Factor (MIF)-Induced Expression of COL1A1.

Zheng J, Guo R, Tang Y, Fu Q, Chen J, Wu L, Leng L, Bucala R, Song Y, Lu L.

Front Immunol. 2019 Feb 6;10:158. doi: 10.3389/fimmu.2019.00158. eCollection 2019.

17.

Inhibition of Interleukin-1β Signaling by Anakinra Demonstrates a Critical Role of Bone Loss in Experimental Arthritogenic Alphavirus Infections.

Wolf S, Taylor A, Zaid A, Freitas J, Herrero LJ, Rao S, Suhrbier A, Forwood MR, Bucala R, Mahalingam S.

Arthritis Rheumatol. 2019 Jul;71(7):1185-1190. doi: 10.1002/art.40856. Epub 2019 Jun 6.

PMID:
30747500
18.

Macrophage migration inhibitory factor polymorphisms are a potential susceptibility marker in systemic sclerosis from southern Mexican population: association with MIF mRNA expression and cytokine profile.

Baños-Hernández CJ, Navarro-Zarza JE, Bucala R, Hernández-Bello J, Parra-Rojas I, Ramírez-Dueñas MG, García-Arellano S, Hernández-Palma LA, Machado-Sulbarán AC, Muñoz-Valle JF.

Clin Rheumatol. 2019 Jun;38(6):1643-1654. doi: 10.1007/s10067-019-04459-8. Epub 2019 Feb 12.

PMID:
30747392
19.

Spinal macrophage migration inhibitory factor and high mobility group box 1 mediate persistent bladder pain.

Ma F, Meyer-Siegler KL, Leng L, Bucala R, Vera PL.

Neurosci Lett. 2019 Apr 23;699:54-58. doi: 10.1016/j.neulet.2019.01.046. Epub 2019 Jan 29.

PMID:
30708129
20.

Th1/Th17 Cytokine Profile is Induced by Macrophage Migration Inhibitory Factor in Peripheral Blood Mononuclear Cells from Rheumatoid Arthritis Patients.

García-Arellano S, Hernández-Palma LA, Bucala R, Hernández-Bello J, De la Cruz-Mosso U, García-Iglesias T, Cerpa-Cruz S, Padilla-Gutiérrez JR, Valle Y, Soñanez-Organis JG, Parra-Rojas I, Pereira-Suárez AL, Muñoz-Valle JF.

Curr Mol Med. 2018;18(10):679-688. doi: 10.2174/1566524019666190129123240.

PMID:
30698113
21.

Evolving complexity of MIF signaling.

Jankauskas SS, Wong DWL, Bucala R, Djudjaj S, Boor P.

Cell Signal. 2019 May;57:76-88. doi: 10.1016/j.cellsig.2019.01.006. Epub 2019 Jan 23. Review.

PMID:
30682543
22.

Editorial: A Fresh New Look, and a Fresh New Journal.

Bucala RJ, Hannan MT.

Arthritis Rheumatol. 2019 Jan;71(1):1. doi: 10.1002/art.40717. No abstract available.

PMID:
30589521
23.

A functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacity.

Zhang C, Ramsey C, Berical A, Yu L, Leng L, McGinnis KA, Song Y, Michael H, McCormack MC, Allore H, Morris A, Crothers K, Bucala R, Lee PJ, Sauler M.

Am J Physiol Lung Cell Mol Physiol. 2019 Feb 1;316(2):L400-L405. doi: 10.1152/ajplung.00439.2018. Epub 2018 Dec 6.

PMID:
30520689
24.

Functional MIF promoter haplotypes modulate Th17-related cytokine expression in peripheral blood mononuclear cells from control subjects and rheumatoid arthritis patients.

Hernández-Palma LA, García-Arellano S, Bucala R, Llamas-Covarrubias MA, De la Cruz-Mosso U, Oregon-Romero E, Cerpa-Cruz S, Parra-Rojas I, Plascencia-Hernández A, Muñoz-Valle JF.

Cytokine. 2019 Mar;115:89-96. doi: 10.1016/j.cyto.2018.11.014. Epub 2018 Nov 19.

PMID:
30467094
25.

Macrophage Migration Inhibitory Factor (MIF) Drives Murine Psoriasiform Dermatitis.

Bezdek S, Leng L, Busch H, Mousavi S, Rades D, Dahlke M, Zillikens D, Bucala R, Sadik CD.

Front Immunol. 2018 Oct 2;9:2262. doi: 10.3389/fimmu.2018.02262. eCollection 2018.

26.

Macrophage migration inhibitory factor mediates metabolic dysfunction induced by atypical antipsychotic therapy.

Cui D, Peng Y, Zhang C, Li Z, Su Y, Qi Y, Xing M, Li J, Kim GE, Su KN, Xu J, Wang M, Ding W, Piecychna M, Leng L, Hirasawa M, Jiang K, Young L, Xu Y, Qi D, Bucala R.

J Clin Invest. 2018 Nov 1;128(11):4997-5007. doi: 10.1172/JCI93090. Epub 2018 Oct 8.

27.

Endothelial cell-secreted MIF reduces pericyte contractility and enhances neutrophil extravasation.

Pellowe AS, Sauler M, Hou Y, Merola J, Liu R, Calderon B, Lauridsen HM, Harris MR, Leng L, Zhang Y, Tilstam PV, Pober JS, Bucala R, Lee PJ, Gonzalez AL.

FASEB J. 2019 Feb;33(2):2171-2186. doi: 10.1096/fj.201800480R. Epub 2018 Sep 25.

PMID:
30252532
28.

Editorial: A Fresh New Look, and a Fresh New Journal.

Hannan MT, Bucala RJ.

Arthritis Care Res (Hoboken). 2019 Jan;71(1):1. doi: 10.1002/acr.23751. No abstract available.

PMID:
30199145
29.

Protease activated-receptor 4 activation as a model of persistent bladder pain: Essential role of macrophage migration inhibitory factor and high mobility group box 1.

Ma F, Hunt DE, Leng L, Bucala R, Meyer-Siegler KL, Vera PL.

Int J Urol. 2018 Oct;25(10):887-893. doi: 10.1111/iju.13778. Epub 2018 Aug 15.

30.

Macrophage Migration Inhibitory Factor Regulates U1 Small Nuclear RNP Immune Complex-Mediated Activation of the NLRP3 Inflammasome.

Shin MS, Kang Y, Wahl ER, Park HJ, Lazova R, Leng L, Mamula M, Krishnaswamy S, Bucala R, Kang I.

Arthritis Rheumatol. 2019 Jan;71(1):109-120. doi: 10.1002/art.40672. Epub 2018 Dec 4.

PMID:
30009530
31.

Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection.

Baeza Garcia A, Siu E, Sun T, Exler V, Brito L, Hekele A, Otten G, Augustijn K, Janse CJ, Ulmer JB, Bernhagen J, Fikrig E, Geall A, Bucala R.

Nat Commun. 2018 Jul 13;9(1):2714. doi: 10.1038/s41467-018-05041-7.

32.
33.

Role of Macrophage Migration Inhibitory Factor in Granulomatosis With Polyangiitis.

Sreih AG, Ezzedine R, Leng L, Fan J, Yao J, Reid D, Piecychna M, Carette S, Cuthbertson D, Dellaripa P, Hoffman GS, Khalidi NA, Koening CL, Langford CA, Mahr A, McAlear CA, Maksimowicz-Mckinnon K, Monach PA, Seo P, Specks U, St Clair EW, Stone JH, Ytterberg SR, Edberg J, Merkel PA, Bucala R.

Arthritis Rheumatol. 2018 Dec;70(12):2077-2086. doi: 10.1002/art.40655. Epub 2018 Oct 22.

34.

Neutralization of macrophage migration inhibitory factor improves host survival after Clostridium difficile infection.

Jose S, Mukherjee A, Abhyankar MM, Leng L, Bucala R, Sharma D, Madan R.

Anaerobe. 2018 Oct;53:56-63. doi: 10.1016/j.anaerobe.2018.06.014. Epub 2018 Jun 23.

35.

TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells.

Valiño-Rivas L, Cuarental L, Grana O, Bucala R, Leng L, Sanz A, Gomez G, Ortiz A, Sanchez-Niño MD.

PLoS One. 2018 Jun 20;13(6):e0199391. doi: 10.1371/journal.pone.0199391. eCollection 2018.

36.

Macrophage migration inhibitory factor (MIF) gene is associated with adolescents' cortisol reactivity and anxiety.

Lipschutz R, Bick J, Nguyen V, Lee M, Leng L, Grigorenko E, Bucala R, Mayes LC, Crowley MJ.

Psychoneuroendocrinology. 2018 Sep;95:170-178. doi: 10.1016/j.psyneuen.2018.05.033. Epub 2018 May 26.

PMID:
29870971
37.

Structural Plasticity in the C-Terminal Region of Macrophage Migration Inhibitory Factor-2 Is Associated with an Induced Fit Mechanism for a Selective Inhibitor.

Pantouris G, Bucala R, Lolis EJ.

Biochemistry. 2018 Jul 3;57(26):3599-3605. doi: 10.1021/acs.biochem.8b00344. Epub 2018 Jun 12.

38.

The protective role of macrophage migration inhibitory factor in acute kidney injury after cardiac surgery.

Stoppe C, Averdunk L, Goetzenich A, Soppert J, Marlier A, Kraemer S, Vieten J, Coburn M, Kowark A, Kim BS, Marx G, Rex S, Ochi A, Leng L, Moeckel G, Linkermann A, El Bounkari O, Zarbock A, Bernhagen J, Djudjaj S, Bucala R, Boor P.

Sci Transl Med. 2018 May 16;10(441). pii: eaan4886. doi: 10.1126/scitranslmed.aan4886.

PMID:
29769287
39.

Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.

Pantouris G, Ho J, Shah D, Syed MA, Leng L, Bhandari V, Bucala R, Batista VS, Loria JP, Lolis EJ.

Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7116-7119. doi: 10.1002/anie.201803191. Epub 2018 May 9.

40.

Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis.

Schmitz C, Noels H, El Bounkari O, Straussfeld E, Megens RTA, Sternkopf M, Alampour-Rajabi S, Krammer C, Tilstam PV, Gerdes N, Bürger C, Kapurniotu A, Bucala R, Jankowski J, Weber C, Bernhagen J.

FASEB J. 2018 Aug;32(8):4428-4443. doi: 10.1096/fj.201800058R. Epub 2018 Mar 15.

41.

Novel half-life extended anti-MIF nanobodies protect against endotoxic shock.

Sparkes A, De Baetselier P, Brys L, Cabrito I, Sterckx YG, Schoonooghe S, Muyldermans S, Raes G, Bucala R, Vanlandschoot P, Van Ginderachter JA, Stijlemans B.

FASEB J. 2018 Jun;32(6):3411-3422. doi: 10.1096/fj.201701189R. Epub 2018 Jan 25.

42.

MIF promotes a differential Th1/Th2/Th17 inflammatory response in human primary cell cultures: Predominance of Th17 cytokine profile in PBMC from healthy subjects and increase of IL-6 and TNF-α in PBMC from active SLE patients.

De la Cruz-Mosso U, García-Iglesias T, Bucala R, Estrada-García I, González-López L, Cerpa-Cruz S, Parra-Rojas I, Gámez-Nava JI, Pérez-Guerrero EE, Muñoz-Valle JF.

Cell Immunol. 2018 Feb;324:42-49. doi: 10.1016/j.cellimm.2017.12.010. Epub 2017 Dec 26.

PMID:
29397904
43.

The Tumor-Like Phenotype of Rheumatoid Synovium: Molecular Profiling and Prospects for Precision Medicine.

You S, Koh JH, Leng L, Kim WU, Bucala R.

Arthritis Rheumatol. 2018 May;70(5):637-652. doi: 10.1002/art.40406. Epub 2018 Mar 31. Review.

44.

Macrophage migration inhibitory factor mediates protease-activated receptor 4-induced bladder pain through urothelial high mobility group box 1.

Ma F, Kouzoukas DE, Meyer-Siegler KL, Hunt DE, Leng L, Bucala R, Vera PL.

Physiol Rep. 2017 Dec;5(24). pii: e13549. doi: 10.14814/phy2.13549.

45.

MIF and D-DT are potential disease severity modifiers in male MS subjects.

Benedek G, Meza-Romero R, Jordan K, Zhang Y, Nguyen H, Kent G, Li J, Siu E, Frazer J, Piecychna M, Du X, Sreih A, Leng L, Wiedrick J, Caillier SJ, Offner H, Oksenberg JR, Yadav V, Bourdette D, Bucala R, Vandenbark AA.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8421-E8429. doi: 10.1073/pnas.1712288114. Epub 2017 Sep 18.

46.

T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell-Cell Contact Mediated through SLAMF6 and SAP.

Radomir L, Cohen S, Kramer MP, Bakos E, Lewinsky H, Barak A, Porat Z, Bucala R, Stepensky P, Becker-Herman S, Shachar I.

J Immunol. 2017 Oct 15;199(8):2745-2757. doi: 10.4049/jimmunol.1700557. Epub 2017 Sep 13.

47.

Macrophage Migration Inhibitory Factor Limits Renal Inflammation and Fibrosis by Counteracting Tubular Cell Cycle Arrest.

Djudjaj S, Martin IV, Buhl EM, Nothofer NJ, Leng L, Piecychna M, Floege J, Bernhagen J, Bucala R, Boor P.

J Am Soc Nephrol. 2017 Dec;28(12):3590-3604. doi: 10.1681/ASN.2017020190. Epub 2017 Aug 11.

48.

Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis.

Tynan A, Mawhinney L, Armstrong ME, O'Reilly C, Kennedy S, Caraher E, Jülicher K, O'Dwyer D, Maher L, Schaffer K, Fabre A, McKone EF, Leng L, Bucala R, Bernhagen J, Cooke G, Donnelly SC.

FASEB J. 2017 Nov;31(11):5102-5110. doi: 10.1096/fj.201700463R. Epub 2017 Aug 2.

49.

Complexity of macrophage migration inhibitory factor (MIF) and other angiogenic biomarkers profiling in pulmonary arterial hypertension.

Marshall JD, Sauler M, Tonelli A, Rao Y, Bucala R, Lee PJ, Fares WH.

Pulm Circ. 2017 Jul-Sep;7(3):730-733. doi: 10.1177/2045893217724141. Epub 2017 Jul 31.

50.

MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics.

Tilstam PV, Qi D, Leng L, Young L, Bucala R.

Expert Opin Ther Targets. 2017 Jul;21(7):671-683. doi: 10.1080/14728222.2017.1336227. Review.

Supplemental Content

Loading ...
Support Center