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Items: 1 to 50 of 249

1.

A new step towards targeting tau.

Corvol JC, Buée L.

Lancet Neurol. 2019 Jun;18(6):517-518. doi: 10.1016/S1474-4422(19)30161-9. No abstract available.

PMID:
31122487
2.

Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody.

Albert M, Mairet-Coello G, Danis C, Lieger S, Caillierez R, Carrier S, Skrobala E, Landrieu I, Michel A, Schmitt M, Citron M, Downey P, Courade JP, Buée L, Colin M.

Brain. 2019 Jun 1;142(6):1736-1750. doi: 10.1093/brain/awz100.

3.

New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease.

Sergeant N, Vingtdeux V, Eddarkaoui S, Gay M, Evrard C, Le Fur N, Laurent C, Caillierez R, Obriot H, Larchanché PE, Farce A, Coevoet M, Carato P, Kouach M, Descat A, Dallemagne P, Buée-Scherrer V, Blum D, Hamdane M, Buée L, Melnyk P.

Neurobiol Dis. 2019 Mar 27. pii: S0969-9961(18)30327-9. doi: 10.1016/j.nbd.2019.03.028. [Epub ahead of print]

PMID:
30928644
4.

Corrigendum: Somatostatin and Neuropeptide Y in Cerebrospinal Fluid: Correlations With Amyloid Peptides Aß1-42, and Tau Proteins in Elderly Patients With Mild Cognitive Impairment.

Duron E, Vidal JS, Grousselle D, Gabelle A, Lehmann S, Pasquier F, Bombois S, Buée L, Allinquant B, Schraen-Maschke S, Baret C, Rigaud AS, Hanon O, Epelbaum J.

Front Aging Neurosci. 2019 Feb 19;11:11. doi: 10.3389/fnagi.2019.00011. eCollection 2019.

5.

Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process.

Domise M, Sauvé F, Didier S, Caillerez R, Bégard S, Carrier S, Colin M, Marinangeli C, Buée L, Vingtdeux V.

Cell Death Dis. 2019 Mar 4;10(3):221. doi: 10.1038/s41419-019-1464-x.

6.

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

Fichou Y, Al-Hilaly YK, Devred F, Smet-Nocca C, Tsvetkov PO, Verelst J, Winderickx J, Geukens N, Vanmechelen E, Perrotin A, Serpell L, Hanseeuw BJ, Medina M, Buée L, Landrieu I.

Acta Neuropathol Commun. 2019 Mar 1;7(1):31. doi: 10.1186/s40478-019-0682-x. Review.

7.

Genetic ablation of tau in postnatal neurons rescues decreased adult hippocampal neurogenesis in a tauopathy model.

Houben S, Leroy K, Ando K, Yilmaz Z, Widomski C, Buée L, Brion JP.

Neurobiol Dis. 2019 Feb 26;127:131-141. doi: 10.1016/j.nbd.2019.02.021. [Epub ahead of print]

PMID:
30818066
8.

A walk through tau therapeutic strategies.

Jadhav S, Avila J, Schöll M, Kovacs GG, Kövari E, Skrabana R, Evans LD, Kontsekova E, Malawska B, de Silva R, Buee L, Zilka N.

Acta Neuropathol Commun. 2019 Feb 15;7(1):22. doi: 10.1186/s40478-019-0664-z. Review.

9.

Brain insulin response and peripheral metabolic changes in a Tau transgenic mouse model.

Leboucher A, Ahmed T, Caron E, Tailleux A, Raison S, Joly-Amado A, Marciniak E, Carvalho K, Hamdane M, Bantubungi K, Lancel S, Eddarkaoui S, Caillierez R, Vallez E, Staels B, Vieau D, Balschun D, Buee L, Blum D.

Neurobiol Dis. 2019 May;125:14-22. doi: 10.1016/j.nbd.2019.01.008. Epub 2019 Jan 19.

PMID:
30665005
10.

Clustering of Tau fibrils impairs the synaptic composition of α3-Na+/K+-ATPase and AMPA receptors.

Shrivastava AN, Redeker V, Pieri L, Bousset L, Renner M, Madiona K, Mailhes-Hamon C, Coens A, Buée L, Hantraye P, Triller A, Melki R.

EMBO J. 2019 Feb 1;38(3). pii: e99871. doi: 10.15252/embj.201899871. Epub 2019 Jan 10.

11.

Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing.

Evrard C, Kienlen-Campard P, Coevoet M, Opsomer R, Tasiaux B, Melnyk P, Octave JN, Buée L, Sergeant N, Vingtdeux V.

Front Cell Neurosci. 2018 Nov 22;12:435. doi: 10.3389/fncel.2018.00435. eCollection 2018.

12.

[Brain insulin signaling and Tau: impact for Alzheimer's disease and Tauopathies].

Joly-Amado A, Gratuze M, Benderradji H, Vieau D, Buée L, Blum D.

Med Sci (Paris). 2018 Nov;34(11):929-935. doi: 10.1051/medsci/2018238. Epub 2018 Dec 10. Review. French.

PMID:
30526837
13.

Different tau species lead to heterogeneous tau pathology propagation and misfolding.

Dujardin S, Bégard S, Caillierez R, Lachaud C, Carrier S, Lieger S, Gonzalez JA, Deramecourt V, Déglon N, Maurage CA, Frosch MP, Hyman BT, Colin M, Buée L.

Acta Neuropathol Commun. 2018 Nov 29;6(1):132. doi: 10.1186/s40478-018-0637-7.

14.

AMP-activated Protein Kinase Controls Immediate Early Genes Expression Following Synaptic Activation Through the PKA/CREB Pathway.

Didier S, Sauvé F, Domise M, Buée L, Marinangeli C, Vingtdeux V.

Int J Mol Sci. 2018 Nov 22;19(12). pii: E3716. doi: 10.3390/ijms19123716.

15.

AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic Activation.

Marinangeli C, Didier S, Ahmed T, Caillerez R, Domise M, Laloux C, Bégard S, Carrier S, Colin M, Marchetti P, Ghesquière B, Balschun D, Buée L, Kluza J, Vingtdeux V.

iScience. 2018 Nov 30;9:1-13. doi: 10.1016/j.isci.2018.10.006. Epub 2018 Oct 12.

16.

Somatostatin and Neuropeptide Y in Cerebrospinal Fluid: Correlations With Amyloid Peptides Aβ1-42 and Tau Proteins in Elderly Patients With Mild Cognitive Impairment.

Duron E, Vidal JS, Grousselle D, Gabelle A, Lehmann S, Pasquier F, Buée L, Allinquant B, Schraen-Maschke S, Baret C, Rigaud AS, Hanon O, Epelbaum J.

Front Aging Neurosci. 2018 Oct 1;10:297. doi: 10.3389/fnagi.2018.00297. eCollection 2018. Erratum in: Front Aging Neurosci. 2019 Feb 19;11:11.

17.

Genome-wide identification of genic and intergenic neuronal DNA regions bound by Tau protein under physiological and stress conditions.

Benhelli-Mokrani H, Mansuroglu Z, Chauderlier A, Albaud B, Gentien D, Sommer S, Schirmer C, Laqueuvre L, Josse T, Buée L, Lefebvre B, Galas MC, Souès S, Bonnefoy E.

Nucleic Acids Res. 2018 Nov 30;46(21):11405-11422. doi: 10.1093/nar/gky929.

18.

Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology.

Sierksma A, Lu A, Salta E, Vanden Eynden E, Callaerts-Vegh Z, D'Hooge R, Blum D, Buée L, Fiers M, De Strooper B.

Mol Neurodegener. 2018 Oct 12;13(1):54. doi: 10.1186/s13024-018-0285-1.

19.

Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.

Chatterjee S, Cassel R, Schneider-Anthony A, Merienne K, Cosquer B, Tzeplaeff L, Halder Sinha S, Kumar M, Chaturbedy P, Eswaramoorthy M, Le Gras S, Keime C, Bousiges O, Dutar P, Petsophonsakul P, Rampon C, Cassel JC, Buée L, Blum D, Kundu TK, Boutillier AL.

EMBO Mol Med. 2018 Nov;10(11). pii: e8587. doi: 10.15252/emmm.201708587.

20.

A phenotypic approach to the discovery of compounds that promote non-amyloidogenic processing of the amyloid precursor protein: Toward a new profile of indirect β-secretase inhibitors.

Gay M, Evrard C, Descamps F, Carato P, Renault N, Coevoet M, Eddarkaoui S, Baud C, Larchanché PE, Buée L, El Bakali J, Vingtdeux V, Sergeant N, Melnyk P.

Eur J Med Chem. 2018 Nov 5;159:104-125. doi: 10.1016/j.ejmech.2018.08.092. Epub 2018 Sep 22.

PMID:
30268822
21.

The Adenosinergic Signaling: A Complex but Promising Therapeutic Target for Alzheimer's Disease.

Cellai L, Carvalho K, Faivre E, Deleau A, Vieau D, Buée L, Blum D, Mériaux C, Gomez-Murcia V.

Front Neurosci. 2018 Aug 3;12:520. doi: 10.3389/fnins.2018.00520. eCollection 2018. Review.

22.

Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease.

Faivre E, Coelho JE, Zornbach K, Malik E, Baqi Y, Schneider M, Cellai L, Carvalho K, Sebda S, Figeac M, Eddarkaoui S, Caillierez R, Chern Y, Heneka M, Sergeant N, Müller CE, Halle A, Buée L, Lopes LV, Blum D.

Front Mol Neurosci. 2018 Jul 12;11:235. doi: 10.3389/fnmol.2018.00235. eCollection 2018.

23.

The Role of Adenosine Tone and Adenosine Receptors in Huntington's Disease.

Blum D, Chern Y, Domenici MR, Buée L, Lin CY, Rea W, Ferré S, Popoli P.

J Caffeine Adenosine Res. 2018 Jun 1;8(2):43-58. doi: 10.1089/caff.2018.0006. Review.

24.

A-kinase anchor protein 4 precursor (pro-AKAP4) in human spermatozoa.

Jumeau F, Sigala J, Dossou-Gbete F, Frimat K, Barbotin AL, Buée L, Béhal H, Sergeant N, Mitchell V.

Andrology. 2018 Nov;6(6):854-859. doi: 10.1111/andr.12524. Epub 2018 Jul 8.

PMID:
29984477
25.

Tau/DDX6 interaction increases microRNA activity.

Chauderlier A, Gilles M, Spolcova A, Caillierez R, Chwastyniak M, Kress M, Drobecq H, Bonnefoy E, Pinet F, Weil D, Buée L, Galas MC, Lefebvre B.

Biochim Biophys Acta Gene Regul Mech. 2018 Aug;1861(8):762-772. doi: 10.1016/j.bbagrm.2018.06.006. Epub 2018 Jun 30.

PMID:
29966762
26.

Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors.

Temido-Ferreira M, Ferreira DG, Batalha VL, Marques-Morgado I, Coelho JE, Pereira P, Gomes R, Pinto A, Carvalho S, Canas PM, Cuvelier L, Buée-Scherrer V, Faivre E, Baqi Y, Müller CE, Pimentel J, Schiffmann SN, Buée L, Bader M, Outeiro TF, Blum D, Cunha RA, Marie H, Pousinha PA, Lopes LV.

Mol Psychiatry. 2018 Jun 27. doi: 10.1038/s41380-018-0110-9. [Epub ahead of print]

PMID:
29950682
27.

Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?

Laurent C, Buée L, Blum D.

Biomed J. 2018 Feb;41(1):21-33. doi: 10.1016/j.bj.2018.01.003. Epub 2018 Mar 20. Review.

28.

Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer's Disease.

Lee CC, Chang CP, Lin CJ, Lai HL, Kao YH, Cheng SJ, Chen HM, Liao YP, Faivre E, Buée L, Blum D, Fang JM, Chern Y.

Mol Neurobiol. 2018 Dec;55(12):8936-8952. doi: 10.1007/s12035-018-1030-z. Epub 2018 Apr 4.

PMID:
29616397
29.

New phenylaniline derivatives as modulators of amyloid protein precursor metabolism.

Gay M, Carato P, Coevoet M, Renault N, Larchanché PE, Barczyk A, Yous S, Buée L, Sergeant N, Melnyk P.

Bioorg Med Chem. 2018 May 1;26(8):2151-2164. doi: 10.1016/j.bmc.2018.03.016. Epub 2018 Mar 12.

PMID:
29559198
30.

Study of AMPK-Regulated Metabolic Fluxes in Neurons Using the Seahorse XFe Analyzer.

Marinangeli C, Kluza J, Marchetti P, Buée L, Vingtdeux V.

Methods Mol Biol. 2018;1732:289-305. doi: 10.1007/978-1-4939-7598-3_19.

PMID:
29480483
31.

Plasma amyloid levels within the Alzheimer's process and correlations with central biomarkers.

Hanon O, Vidal JS, Lehmann S, Bombois S, Allinquant B, Tréluyer JM, Gelé P, Delmaire C, Blanc F, Mangin JF, Buée L, Touchon J, Hugon J, Vellas B, Galbrun E, Benetos A, Berrut G, Paillaud E, Wallon D, Castelnovo G, Volpe-Gillot L, Paccalin M, Robert PH, Godefroy O, Dantoine T, Camus V, Belmin J, Vandel P, Novella JL, Duron E, Rigaud AS, Schraen-Maschke S, Gabelle A; BALTAZAR study group.

Alzheimers Dement. 2018 Jul;14(7):858-868. doi: 10.1016/j.jalz.2018.01.004. Epub 2018 Feb 17.

32.

Mutual Relationship between Tau and Central Insulin Signalling: Consequences for AD and Tauopathies?

Gratuze M, Joly-Amado A, Vieau D, Buée L, Blum D.

Neuroendocrinology. 2018;107(2):181-195. doi: 10.1159/000487641. Epub 2018 Feb 13. Review.

33.

Relevance of Follow-Up in Patients with Core Clinical Criteria for Alzheimer Disease and Normal CSF Biomarkers.

Vercruysse O, Paquet C, Gabelle A, Delbeuck X, Blanc F, Wallon D, Dumurgier J, Magnin E, Martinaud O, Jung B, Bousiges O, Lehmann S, Delaby C, Quillard-Murain M, Peoc H K, Laplanche JL, Bouaziz-Amar E, Hannequin D, Sablonniere B, Buee L, Hugon J, Schraen S, Pasquier F, Bombois S, For The E-Plm Group.

Curr Alzheimer Res. 2018;15(7):691-700. doi: 10.2174/1567205015666180110113238.

PMID:
29318973
34.

What is the evidence that tau pathology spreads through prion-like propagation?

Mudher A, Colin M, Dujardin S, Medina M, Dewachter I, Alavi Naini SM, Mandelkow EM, Mandelkow E, Buée L, Goedert M, Brion JP.

Acta Neuropathol Commun. 2017 Dec 19;5(1):99. doi: 10.1186/s40478-017-0488-7. Review.

35.

Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat.

d'Orange M, Aurégan G, Cheramy D, Gaudin-Guérif M, Lieger S, Guillermier M, Stimmer L, Joséphine C, Hérard AS, Gaillard MC, Petit F, Kiessling MC, Schmitz C, Colin M, Buée L, Panayi F, Diguet E, Brouillet E, Hantraye P, Bemelmans AP, Cambon K.

Brain. 2018 Feb 1;141(2):535-549. doi: 10.1093/brain/awx342.

36.

Atypical, non-standard functions of the microtubule associated Tau protein.

Sotiropoulos I, Galas MC, Silva JM, Skoulakis E, Wegmann S, Maina MB, Blum D, Sayas CL, Mandelkow EM, Mandelkow E, Spillantini MG, Sousa N, Avila J, Medina M, Mudher A, Buee L.

Acta Neuropathol Commun. 2017 Nov 29;5(1):91. doi: 10.1186/s40478-017-0489-6. Review.

37.

EuroTau: towing scientists to tau without tautology.

Mudher A, Brion JP, Avila J, Medina M, Buée L.

Acta Neuropathol Commun. 2017 Nov 29;5(1):90. doi: 10.1186/s40478-017-0491-z. No abstract available.

38.

[Tau and cognitive disorders: a role for T lymphocytes].

Laurent C, Dorothée G, Hunot S, Martin E, Delarasse C, Buée L, Blum D.

Med Sci (Paris). 2017 Oct;33(10):817-819. doi: 10.1051/medsci/20173310002. Epub 2017 Oct 10. French. No abstract available.

39.

Alternative promoter usage generates novel shorter MAPT mRNA transcripts in Alzheimer's disease and progressive supranuclear palsy brains.

Huin V, Buée L, Behal H, Labreuche J, Sablonnière B, Dhaenens CM.

Sci Rep. 2017 Oct 3;7(1):12589. doi: 10.1038/s41598-017-12955-7.

40.

Update on tauopathies.

Lebouvier T, Pasquier F, Buée L.

Curr Opin Neurol. 2017 Dec;30(6):589-598. doi: 10.1097/WCO.0000000000000502. Review.

PMID:
28914736
41.

Tau deletion promotes brain insulin resistance.

Marciniak E, Leboucher A, Caron E, Ahmed T, Tailleux A, Dumont J, Issad T, Gerhardt E, Pagesy P, Vileno M, Bournonville C, Hamdane M, Bantubungi K, Lancel S, Demeyer D, Eddarkaoui S, Vallez E, Vieau D, Humez S, Faivre E, Grenier-Boley B, Outeiro TF, Staels B, Amouyel P, Balschun D, Buee L, Blum D.

J Exp Med. 2017 Aug 7;214(8):2257-2269. doi: 10.1084/jem.20161731. Epub 2017 Jun 26.

42.

Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly.

Shelkovnikova TA, Dimasi P, Kukharsky MS, An H, Quintiero A, Schirmer C, Buée L, Galas MC, Buchman VL.

Cell Death Dis. 2017 May 11;8(5):e2788. doi: 10.1038/cddis.2017.199.

43.

Amyloid precursor protein reduction enhances the formation of neurofibrillary tangles in a mutant tau transgenic mouse model.

Vanden Dries V, Stygelbout V, Pierrot N, Yilmaz Z, Suain V, De Decker R, Buée L, Octave JN, Brion JP, Leroy K.

Neurobiol Aging. 2017 Jul;55:202-212. doi: 10.1016/j.neurobiolaging.2017.03.031. Epub 2017 Apr 5.

PMID:
28464981
44.

Defining the human sperm microtubulome: an integrated genomics approach.

Jumeau F, Chalmel F, Fernandez-Gomez FJ, Carpentier C, Obriot H, Tardivel M, Caillet-Boudin ML, Rigot JM, Rives N, Buée L, Sergeant N, Mitchell V.

Biol Reprod. 2017 Jan 1;96(1):93-106. doi: 10.1095/biolreprod.116.143479.

PMID:
28395323
45.
46.

Two-Dimensional Electrophoresis Protocols to Analyze the Microtubule-Associated Tau Proteins from Several Biological Sources.

Sergeant N, Fernandez-Gomez FJ, Obriot H, Eddarkaoui S, Buée-Scherrer V, Buée L.

Methods Mol Biol. 2017;1523:251-261.

PMID:
27975254
47.

Omics analysis of mouse brain models of human diseases.

Paban V, Loriod B, Villard C, Buee L, Blum D, Pietropaolo S, Cho YH, Gory-Faure S, Mansour E, Gharbi A, Alescio-Lautier B.

Gene. 2017 Feb 5;600:90-100. doi: 10.1016/j.gene.2016.11.022. Epub 2016 Nov 18.

PMID:
27871923
48.

Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy.

Laurent C, Dorothée G, Hunot S, Martin E, Monnet Y, Duchamp M, Dong Y, Légeron FP, Leboucher A, Burnouf S, Faivre E, Carvalho K, Caillierez R, Zommer N, Demeyer D, Jouy N, Sazdovitch V, Schraen-Maschke S, Delarasse C, Buée L, Blum D.

Brain. 2017 Jan;140(1):184-200. doi: 10.1093/brain/aww270. Epub 2016 Nov 5.

49.

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies.

Tardivel M, Bégard S, Bousset L, Dujardin S, Coens A, Melki R, Buée L, Colin M.

Acta Neuropathol Commun. 2016 Nov 4;4(1):117.

50.

The MAPT gene is differentially methylated in the progressive supranuclear palsy brain.

Huin V, Deramecourt V, Caparros-Lefebvre D, Maurage CA, Duyckaerts C, Kovari E, Pasquier F, Buée-Scherrer V, Labreuche J, Behal H, Buée L, Dhaenens CM, Sablonnière B.

Mov Disord. 2016 Dec;31(12):1883-1890. doi: 10.1002/mds.26820. Epub 2016 Oct 6.

PMID:
27709663

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