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Items: 41


A motor-driven adjustable prosthetic socket operated using a mobile phone app: A technical note.

Sanders JE, Garbini JL, McLean JB, Hinrichs P, Predmore TJ, Brzostowski JT, Redd CB, Cagle JC.

Med Eng Phys. 2019 Jun;68:94-100. doi: 10.1016/j.medengphy.2019.04.003. Epub 2019 Apr 23.


Socket size adjustments in people with transtibial amputation: Effects on residual limb fluid volume and limb-socket distance.

McLean JB, Redd CB, Larsen BG, Garbini JL, Brzostowski JT, Hafner BJ, Sanders JE.

Clin Biomech (Bristol, Avon). 2019 Mar;63:161-171. doi: 10.1016/j.clinbiomech.2019.02.022. Epub 2019 Mar 2.


Adjustable sockets may improve residual limb fluid volume retention in transtibial prosthesis users.

Brzostowski JT, Larsen BG, Youngblood RT, Ciol MA, Hafner BJ, Gurrey CJ, McLean JB, Allyn KJ, Sanders JE.

Prosthet Orthot Int. 2019 Jun;43(3):250-256. doi: 10.1177/0309364618820140. Epub 2019 Jan 10.


Intrinsic properties of human germinal center B cells set antigen affinity thresholds.

Kwak K, Quizon N, Sohn H, Saniee A, Manzella-Lapeira J, Holla P, Brzostowski J, Lu J, Xie H, Xu C, Spillane KM, Tolar P, Pierce SK.

Sci Immunol. 2018 Nov 30;3(29). pii: eaau6598. doi: 10.1126/sciimmunol.aau6598.


Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4+ T Cell Activation.

Akkaya B, Roesler AS, Miozzo P, Theall BP, Al Souz J, Smelkinson MG, Kabat J, Traba J, Sack MN, Brzostowski JA, Pena M, Dorward DW, Pierce SK, Akkaya M.

J Immunol. 2018 Dec 1;201(11):3294-3306. doi: 10.4049/jimmunol.1800753. Epub 2018 Oct 29.


Cutting Edge: Quantitative Determination of CD40L Threshold for IL-12 and IL-23 Production from Dendritic Cells.

Abdi K, Laky K, Padhan K, Petrovas C, Skinner J, Kabat J, Dorward DW, Brzostowski J, Long EO, Trinchieri G, Varma R.

J Immunol. 2018 Nov 15;201(10):2879-2884. doi: 10.4049/jimmunol.1800721. Epub 2018 Oct 12.


Imaging Protein-Protein Interactions by Förster Resonance Energy Transfer (FRET) Microscopy in Live Cells.

Manzella-Lapeira J, Brzostowski JA.

Curr Protoc Protein Sci. 2018 Aug;93(1):e58. doi: 10.1002/cpps.58. Epub 2018 Jul 9.


NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody-dependent cellular cytotoxicity.

Arora G, Hart GT, Manzella-Lapeira J, Doritchamou JY, Narum DL, Thomas LM, Brzostowski J, Rajagopalan S, Doumbo OK, Traore B, Miller LH, Pierce SK, Duffy PE, Crompton PD, Desai SA, Long EO.

Elife. 2018 Jun 26;7. pii: e36806. doi: 10.7554/eLife.36806.


PfCDPK1 is critical for malaria parasite gametogenesis and mosquito infection.

Bansal A, Molina-Cruz A, Brzostowski J, Liu P, Luo Y, Gunalan K, Li Y, Ribeiro JMC, Miller LH.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):774-779. doi: 10.1073/pnas.1715443115. Epub 2018 Jan 8.


Plasmodium falciparum Calcium-Dependent Protein Kinase 2 Is Critical for Male Gametocyte Exflagellation but Not Essential for Asexual Proliferation.

Bansal A, Molina-Cruz A, Brzostowski J, Mu J, Miller LH.

MBio. 2017 Oct 17;8(5). pii: e01656-17. doi: 10.1128/mBio.01656-17.


The Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptake.

Sherling ES, Knuepfer E, Brzostowski JA, Miller LH, Blackman MJ, van Ooij C.

Elife. 2017 Mar 2;6. pii: e23239. doi: 10.7554/eLife.23239.


The nanoscale spatial organization of B-cell receptors on immunoglobulin M- and G-expressing human B-cells.

Lee J, Sengupta P, Brzostowski J, Lippincott-Schwartz J, Pierce SK.

Mol Biol Cell. 2017 Feb 15;28(4):511-523. doi: 10.1091/mbc.E16-06-0452. Epub 2016 Dec 14.


Quantitative Monitoring Spatiotemporal Activation of Ras and PKD1 Using Confocal Fluorescent Microscopy.

Xu X, Yun M, Wen X, Brzostowski J, Quan W, Wang QJ, Jin T.

Methods Mol Biol. 2016;1407:307-23. doi: 10.1007/978-1-4939-3480-5_22.


Arrestins function in cAR1 GPCR-mediated signaling and cAR1 internalization in the development of Dictyostelium discoideum.

Cao X, Yan J, Shu S, Brzostowski JA, Jin T.

Mol Biol Cell. 2014 Oct 15;25(20):3210-21. doi: 10.1091/mbc.E14-03-0834. Epub 2014 Aug 20.


Through an ITIM-independent mechanism the FcγRIIB blocks B cell activation by disrupting the colocalized microclustering of the B cell receptor and CD19.

Xu L, Li G, Wang J, Fan Y, Wan Z, Zhang S, Shaheen S, Li J, Wang L, Yue C, Zhao Y, Wang F, Brzostowski J, Chen YH, Zheng W, Liu W.

J Immunol. 2014 Jun 1;192(11):5179-91. doi: 10.4049/jimmunol.1400101. Epub 2014 Apr 30.


Phosphorylation of chemoattractant receptors regulates chemotaxis, actin reorganization and signal relay.

Brzostowski JA, Sawai S, Rozov O, Liao XH, Imoto D, Parent CA, Kimmel AR.

J Cell Sci. 2013 Oct 15;126(Pt 20):4614-26. doi: 10.1242/jcs.122952. Epub 2013 Jul 31.


The scaffolding protein synapse-associated protein 97 is required for enhanced signaling through isotype-switched IgG memory B cell receptors.

Liu W, Chen E, Zhao XW, Wan ZP, Gao YR, Davey A, Huang E, Zhang L, Crocetti J, Sandoval G, Joyce MG, Miceli C, Lukszo J, Aravind L, Swat W, Brzostowski J, Pierce SK.

Sci Signal. 2012 Jul 31;5(235):ra54. doi: 10.1126/scisignal.2002820.


Understanding the initiation of B cell signaling through live cell imaging.

Davey A, Liu W, Sohn HW, Brzostowski J, Pierce SK.

Methods Enzymol. 2012;506:265-290. doi: 10.1016/B978-0-12-391856-7.00038-X.


A Gβγ effector, ElmoE, transduces GPCR signaling to the actin network during chemotaxis.

Yan J, Mihaylov V, Xu X, Brzostowski JA, Li H, Liu L, Veenstra TD, Parent CA, Jin T.

Dev Cell. 2012 Jan 17;22(1):92-103. doi: 10.1016/j.devcel.2011.11.007.


Cutting edge: NKG2D-dependent cytotoxicity is controlled by ligand distribution in the target cell membrane.

Martinez E, Brzostowski JA, Long EO, Gross CC.

J Immunol. 2011 May 15;186(10):5538-42. doi: 10.4049/jimmunol.1002254. Epub 2011 Apr 4.


Combinatorial cell-specific regulation of GSK3 directs cell differentiation and polarity in Dictyostelium.

Kim L, Brzostowski J, Majithia A, Lee NS, McMains V, Kimmel AR.

Development. 2011 Feb;138(3):421-30. doi: 10.1242/dev.055335.


Coupling mechanism of a GPCR and a heterotrimeric G protein during chemoattractant gradient sensing in Dictyostelium.

Xu X, Meckel T, Brzostowski JA, Yan J, Meier-Schellersheim M, Jin T.

Sci Signal. 2010 Sep 28;3(141):ra71. doi: 10.1126/scisignal.2000980.


Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.

Gross CC, Brzostowski JA, Liu D, Long EO.

J Immunol. 2010 Sep 1;185(5):2918-26. doi: 10.4049/jimmunol.1000761. Epub 2010 Jul 30.


Distinct external signals trigger sequential release of apical organelles during erythrocyte invasion by malaria parasites.

Singh S, Alam MM, Pal-Bhowmick I, Brzostowski JA, Chitnis CE.

PLoS Pathog. 2010 Feb 5;6(2):e1000746. doi: 10.1371/journal.ppat.1000746.


Monitoring dynamic GPCR signaling events using fluorescence microscopy, FRET imaging, and single-molecule imaging.

Xu X, Brzostowski JA, Jin T.

Methods Mol Biol. 2009;571:371-83. doi: 10.1007/978-1-60761-198-1_25.


The Elmo family forms an ancient group of actin-regulating proteins.

Brzostowski JA, Fey P, Yan J, Isik N, Jin T.

Commun Integr Biol. 2009 Jul;2(4):337-40.


Imaging protein-protein interactions by Förster resonance energy transfer (FRET) microscopy in live cells.

Brzostowski JA, Meckel T, Hong J, Chen A, Jin T.

Curr Protoc Protein Sci. 2009 Apr;Chapter 19:Unit19.5. doi: 10.1002/0471140864.ps1905s56.


An Elmo-like protein associated with myosin II restricts spurious F-actin events to coordinate phagocytosis and chemotaxis.

Isik N, Brzostowski JA, Jin T.

Dev Cell. 2008 Oct;15(4):590-602. doi: 10.1016/j.devcel.2008.08.006.


How human leukocytes track down and destroy pathogens: lessons learned from the model organism Dictyostelium discoideum.

Jin T, Xu X, Fang J, Isik N, Yan J, Brzostowski JA, Hereld D.

Immunol Res. 2009;43(1-3):118-27. doi: 10.1007/s12026-008-8056-7. Review.


A vesicle surface tyrosine kinase regulates phagosome maturation.

Fang J, Brzostowski JA, Ou S, Isik N, Nair V, Jin T.

J Cell Biol. 2007 Jul 30;178(3):411-23.


Nonadaptive regulation of ERK2 in Dictyostelium: implications for mechanisms of cAMP relay.

Brzostowski JA, Kimmel AR.

Mol Biol Cell. 2006 Oct;17(10):4220-7. Epub 2006 Jul 26.


A Rab21/LIM-only/CH-LIM complex regulates phagocytosis via both activating and inhibitory mechanisms.

Khurana T, Brzostowski JA, Kimmel AR.

EMBO J. 2005 Jul 6;24(13):2254-64. Epub 2005 Jun 16.


A G alpha-dependent pathway that antagonizes multiple chemoattractant responses that regulate directional cell movement.

Brzostowski JA, Parent CA, Kimmel AR.

Genes Dev. 2004 Apr 1;18(7):805-15. Epub 2004 Apr 1.


Galpha-mediated inhibition of developmental signal response.

Brzostowski JA, Johnson C, Kimmel AR.

Curr Biol. 2002 Jul 23;12(14):1199-208.


Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium.

Miura S, Gan JW, Brzostowski J, Parisi MJ, Schultz CJ, Londos C, Oliver B, Kimmel AR.

J Biol Chem. 2002 Aug 30;277(35):32253-7. Epub 2002 Jun 20.


Signaling at zero G: G-protein-independent functions for 7-TM receptors.

Brzostowski JA, Kimmel AR.

Trends Biochem Sci. 2001 May;26(5):291-7. Review.


RNA-dependent cytoplasmic anchoring of a transcription factor subunit during Xenopus development.

Brzostowski J, Robinson C, Orford R, Elgar S, Scarlett G, Peterkin T, Malartre M, Kneale G, Wormington M, Guille M.

EMBO J. 2000 Jul 17;19(14):3683-93.

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