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Items: 1 to 50 of 80

1.

Combining ddPCR and environmental DNA to improve detection capabilities of a critically endangered freshwater invertebrate.

Mauvisseau Q, Davy-Bowker J, Bulling M, Brys R, Neyrinck S, Troth C, Sweet M.

Sci Rep. 2019 Oct 1;9(1):14064. doi: 10.1038/s41598-019-50571-9.

2.

Influence of accuracy, repeatability and detection probability in the reliability of species-specific eDNA based approaches.

Mauvisseau Q, Burian A, Gibson C, Brys R, Ramsey A, Sweet M.

Sci Rep. 2019 Jan 24;9(1):580. doi: 10.1038/s41598-018-37001-y.

3.

Variability in DNA Methylation and Generational Plasticity in the Lombardy Poplar, a Single Genotype Worldwide Distributed Since the Eighteenth Century.

Vanden Broeck A, Cox K, Brys R, Castiglione S, Cicatelli A, Guarino F, Heinze B, Steenackers M, Vander Mijnsbrugge K.

Front Plant Sci. 2018 Nov 13;9:1635. doi: 10.3389/fpls.2018.01635. eCollection 2018.

4.

Mycorrhizal divergence and selection against immigrant seeds in forest and dune populations of the partially mycoheterotrophic Pyrola rotundifolia.

Jacquemyn H, Waud M, Brys R.

Mol Ecol. 2018 Dec;27(24):5228-5237. doi: 10.1111/mec.14940. Epub 2018 Dec 10.

PMID:
30427084
5.

The impact of floral morphology on genetic differentiation in two closely related biennial plant species.

Mertens A, Brys R, Schouppe D, Jacquemyn H.

AoB Plants. 2018 Sep 7;10(5):ply051. doi: 10.1093/aobpla/ply051. eCollection 2018 Oct.

6.

Correction to Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2- a]pyridine Series of Autotaxin Inhibitors.

Joncour A, Desroy N, Housseman C, Bock X, Bienvenu N, Cherel L, Labeguere V, Peixoto C, Annoot D, Lepissier L, Heiermann J, Hengeveld WJ, Pilzak G, Monjardet A, Wakselman E, Roncoroni V, Le Tallec S, Galien R, David C, Vandervoort N, Christophe T, Conrath K, Jans M, Wohlkonig A, Soror S, Steyaert J, Touitou R, Fleury D, Vercheval L, Mollat P, Triballeau N, van der Aar E, Brys R, Heckmann B.

J Med Chem. 2018 May 10;61(9):4270. doi: 10.1021/acs.jmedchem.8b00579. Epub 2018 Apr 19. No abstract available.

PMID:
29672037
7.

Drivers of vegetative dormancy across herbaceous perennial plant species.

Shefferson RP, Kull T, Hutchings MJ, Selosse MA, Jacquemyn H, Kellett KM, Menges ES, Primack RB, Tuomi J, Alahuhta K, Hurskainen S, Alexander HM, Anderson DS, Brys R, Brzosko E, Dostálik S, Gregg K, Ipser Z, Jäkäläniemi A, Jersáková J, Dean Kettle W, McCormick MK, Mendoza A, Miller MT, Moen A, Øien DI, Püttsepp Ü, Roy M, Sather N, Sletvold N, Štípková Z, Tali K, Warren RJ 2nd, Whigham DF.

Ecol Lett. 2018 May;21(5):724-733. doi: 10.1111/ele.12940. Epub 2018 Mar 25.

PMID:
29575384
8.

Neutralization of IL-17C Reduces Skin Inflammation in Mouse Models of Psoriasis and Atopic Dermatitis.

Vandeghinste N, Klattig J, Jagerschmidt C, Lavazais S, Marsais F, Haas JD, Auberval M, Lauffer F, Moran T, Ongenaert M, Van Balen M, Dupont S, Lepescheux L, Garcia T, Härtle S, Eyerich K, Fallon PG, Brys R, Steidl S.

J Invest Dermatol. 2018 Jul;138(7):1555-1563. doi: 10.1016/j.jid.2018.01.036. Epub 2018 Feb 21.

9.

Mycorrhizal Associations and Trophic Modes in Coexisting Orchids: An Ecological Continuum between Auto- and Mixotrophy.

Jacquemyn H, Waud M, Brys R, Lallemand F, Courty PE, Robionek A, Selosse MA.

Front Plant Sci. 2017 Aug 29;8:1497. doi: 10.3389/fpls.2017.01497. eCollection 2017.

10.

Analysis of spatial genetic variation reveals genetic divergence among populations of Primula veris associated to contrasting habitats.

Deschepper P, Brys R, Fortuna MA, Jacquemyn H.

Sci Rep. 2017 Aug 18;7(1):8847. doi: 10.1038/s41598-017-09154-9.

11.

Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors.

Joncour A, Desroy N, Housseman C, Bock X, Bienvenu N, Cherel L, Labeguere V, Peixoto C, Annoot D, Lepissier L, Heiermann J, Hengeveld WJ, Pilzak G, Monjardet A, Wakselman E, Roncoroni V, Le Tallec S, Galien R, David C, Vandervoort N, Christophe T, Conrath K, Jans M, Wohlkonig A, Soror S, Steyaert J, Touitou R, Fleury D, Vercheval L, Mollat P, Triballeau N, van der Aar E, Brys R, Heckmann B.

J Med Chem. 2017 Sep 14;60(17):7371-7392. doi: 10.1021/acs.jmedchem.7b00647. Epub 2017 Aug 18. Erratum in: J Med Chem. 2018 May 10;61(9):4270.

PMID:
28731719
12.
13.

Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis.

Desroy N, Housseman C, Bock X, Joncour A, Bienvenu N, Cherel L, Labeguere V, Rondet E, Peixoto C, Grassot JM, Picolet O, Annoot D, Triballeau N, Monjardet A, Wakselman E, Roncoroni V, Le Tallec S, Blanque R, Cottereaux C, Vandervoort N, Christophe T, Mollat P, Lamers M, Auberval M, Hrvacic B, Ralic J, Oste L, van der Aar E, Brys R, Heckmann B.

J Med Chem. 2017 May 11;60(9):3580-3590. doi: 10.1021/acs.jmedchem.7b00032. Epub 2017 May 1.

PMID:
28414242
14.

Mycorrhizal specificity does not limit the distribution of an endangered orchid species.

Waud M, Brys R, Van Landuyt W, Lievens B, Jacquemyn H.

Mol Ecol. 2017 Mar;26(6):1687-1701. doi: 10.1111/mec.14014. Epub 2017 Feb 16.

PMID:
28100022
15.

Habitat-driven variation in mycorrhizal communities in the terrestrial orchid genus Dactylorhiza.

Jacquemyn H, Waud M, Merckx VS, Brys R, Tyteca D, Hedrén M, Lievens B.

Sci Rep. 2016 Nov 24;6:37182. doi: 10.1038/srep37182.

16.

The impact of hybridization on long-term persistence of polyploid Dactylorhiza species.

Jacquemyn H, van der Meer S, Brys R.

Am J Bot. 2016 Oct;103(10):1829-1837. Epub 2016 Oct 20.

17.

Differences in mycorrhizal communities between Epipactis palustris, E. helleborine and its presumed sister species E. neerlandica.

Jacquemyn H, Waud M, Lievens B, Brys R.

Ann Bot. 2016 Jul;118(1):105-14. doi: 10.1093/aob/mcw015. Epub 2016 Mar 5.

18.

Nonrandom seedling establishment corresponds with distance-dependent decline in mycorrhizal abundance in two terrestrial orchids.

Waud M, Wiegand T, Brys R, Lievens B, Jacquemyn H.

New Phytol. 2016 Jul;211(1):255-64. doi: 10.1111/nph.13894. Epub 2016 Feb 15.

19.

The influence of herbivory on pre- and postzygotic stages of reproduction following open, self, and outcross pollination.

Ghyselen C, Bonte D, Brys R.

Am J Bot. 2015 Dec;102(12):2013-9. doi: 10.3732/ajb.1500291. Epub 2015 Dec 15.

20.

Severe outbreeding and inbreeding depression maintain mating system differentiation in Epipactis (Orchidaceae).

Brys R, Jacquemyn H.

J Evol Biol. 2016 Feb;29(2):352-9. doi: 10.1111/jeb.12787. Epub 2015 Dec 11.

21.

Mycorrhizal diversity, seed germination and long-term changes in population size across nine populations of the terrestrial orchid Neottia ovata.

Jacquemyn H, Waud M, Merckx VS, Lievens B, Brys R.

Mol Ecol. 2015 Jul;24(13):3269-80. doi: 10.1111/mec.13236. Epub 2015 Jun 5.

PMID:
25963669
22.

Is there a missing link? Effects of root herbivory on plant-pollinator interactions and reproductive output in a monocarpic species.

Ghyselen C, Bonte D, Brys R.

Plant Biol (Stuttg). 2016 Jan;18(1):156-63. doi: 10.1111/plb.12325. Epub 2015 Mar 26.

PMID:
25731922
23.

Mycorrhizal networks and coexistence in species-rich orchid communities.

Jacquemyn H, Brys R, Waud M, Busschaert P, Lievens B.

New Phytol. 2015 May;206(3):1127-34. doi: 10.1111/nph.13281. Epub 2015 Jan 23.

24.

Pollen limitation and the contribution of autonomous selfing to fruit and seed set in a rewarding orchid.

Jacquemyn H, Brys R.

Am J Bot. 2015 Jan;102(1):67-72. doi: 10.3732/ajb.1400449. Epub 2014 Dec 22.

25.

Disruption of the distylous syndrome in Primula veris.

Brys R, Jacquemyn H.

Ann Bot. 2015 Jan;115(1):27-39. doi: 10.1093/aob/mcu211. Epub 2014 Nov 26.

26.

Discovery and optimization of an azetidine chemical series as a free fatty acid receptor 2 (FFA2) antagonist: from hit to clinic.

Pizzonero M, Dupont S, Babel M, Beaumont S, Bienvenu N, Blanqué R, Cherel L, Christophe T, Crescenzi B, De Lemos E, Delerive P, Deprez P, De Vos S, Djata F, Fletcher S, Kopiejewski S, L'Ebraly C, Lefrançois JM, Lavazais S, Manioc M, Nelles L, Oste L, Polancec D, Quénéhen V, Soulas F, Triballeau N, van der Aar EM, Vandeghinste N, Wakselman E, Brys R, Saniere L.

J Med Chem. 2014 Dec 11;57(23):10044-57. doi: 10.1021/jm5012885. Epub 2014 Dec 1.

PMID:
25380412
27.

Triazolopyridines as selective JAK1 inhibitors: from hit identification to GLPG0634.

Menet CJ, Fletcher SR, Van Lommen G, Geney R, Blanc J, Smits K, Jouannigot N, Deprez P, van der Aar EM, Clement-Lacroix P, Lepescheux L, Galien R, Vayssiere B, Nelles L, Christophe T, Brys R, Uhring M, Ciesielski F, Van Rompaey L.

J Med Chem. 2014 Nov 26;57(22):9323-42. doi: 10.1021/jm501262q. Epub 2014 Nov 17.

PMID:
25369270
28.

Secondary pollen presentation and the temporal dynamics of stylar hair retraction and style elongation in Campanula trachelium (Campanulaceae).

Vranken S, Brys R, Hoffmann M, Jacquemyn H.

Plant Biol (Stuttg). 2014 May;16(3):669-76. doi: 10.1111/plb.12097. Epub 2013 Sep 20.

PMID:
24712874
29.

The contribution of mating system variation to reproductive isolation in two closely related Centaurium species (Gentianaceae) with a generalized flower morphology.

Brys R, Vanden Broeck A, Mergeay J, Jacquemyn H.

Evolution. 2014 May;68(5):1281-93. doi: 10.1111/evo.12345. Epub 2014 Feb 1.

PMID:
24372301
30.

Coexisting orchid species have distinct mycorrhizal communities and display strong spatial segregation.

Jacquemyn H, Brys R, Merckx VS, Waud M, Lievens B, Wiegand T.

New Phytol. 2014 Apr;202(2):616-27. doi: 10.1111/nph.12640. Epub 2013 Dec 11.

31.

Preclinical characterization of GLPG0634, a selective inhibitor of JAK1, for the treatment of inflammatory diseases.

Van Rompaey L, Galien R, van der Aar EM, Clement-Lacroix P, Nelles L, Smets B, Lepescheux L, Christophe T, Conrath K, Vandeghinste N, Vayssiere B, De Vos S, Fletcher S, Brys R, van 't Klooster G, Feyen JH, Menet C.

J Immunol. 2013 Oct 1;191(7):3568-77. doi: 10.4049/jimmunol.1201348. Epub 2013 Sep 4.

32.

Among-population variation in microbial community structure in the floral nectar of the bee-pollinated forest herb Pulmonaria officinalis L.

Jacquemyn H, Lenaerts M, Brys R, Willems K, Honnay O, Lievens B.

PLoS One. 2013;8(3):e56917. doi: 10.1371/journal.pone.0056917. Epub 2013 Mar 11.

33.

Differences in dichogamy and herkogamy contribute to higher selfing in contrasting environments in the annual Blackstonia perfoliata (Gentianaceae).

Brys R, Geens B, Beeckman T, Jacquemyn H.

Ann Bot. 2013 Apr;111(4):651-61. doi: 10.1093/aob/mct031. Epub 2013 Feb 13.

34.

Asymmetric gene introgression in two closely related Orchis species: evidence from morphometric and genetic analyses.

Jacquemyn H, Brys R, Honnay O, Roldán-Ruiz I.

BMC Evol Biol. 2012 Sep 12;12:178. doi: 10.1186/1471-2148-12-178.

35.

Evolutionary demography of iteroparous plants: incorporating non-lethal costs of reproduction into integral projection models.

Miller TE, Williams JL, Jongejans E, Brys R, Jacquemyn H.

Proc Biol Sci. 2012 Jul 22;279(1739):2831-40. doi: 10.1098/rspb.2012.0326. Epub 2012 Mar 14.

36.

Discovery of a series of imidazopyrazine small molecule inhibitors of the kinase MAPKAPK5, that show activity using in vitro and in vivo models of rheumatoid arthritis.

Andrews MJ, Clase JA, Bar G, Tricarico G, Edwards PJ, Brys R, Chambers M, Schmidt W, MacLeod A, Hirst K, Allen V, Birault V, Le J, Harris J, Self A, Nash K, Dixon G.

Bioorg Med Chem Lett. 2012 Mar 15;22(6):2266-70. doi: 10.1016/j.bmcl.2012.01.077. Epub 2012 Jan 31.

PMID:
22342143
37.

Biased morph ratios and skewed mating success contribute to loss of genetic diversity in the distylous Pulmonaria officinalis.

Meeus S, Honnay O, Brys R, Jacquemyn H.

Ann Bot. 2012 Jan;109(1):227-35. doi: 10.1093/aob/mcr272. Epub 2011 Oct 21.

38.

Importance of autonomous selfing is inversely related to population size and pollinator availability in a monocarpic plant.

Brys R, de Crop E, Hoffmann M, Jacquemyn H.

Am J Bot. 2011 Nov;98(11):1834-40. doi: 10.3732/ajb.1100154. Epub 2011 Oct 14.

39.

Nonrandom spatial structuring of orchids in a hybrid zone of three Orchis species.

Jacquemyn H, Brys R, Honnay O, Roldán-Ruiz I, Lievens B, Wiegand T.

New Phytol. 2012 Jan;193(2):454-64. doi: 10.1111/j.1469-8137.2011.03913.x. Epub 2011 Sep 28.

40.

Analysis of network architecture reveals phylogenetic constraints on mycorrhizal specificity in the genus Orchis (Orchidaceae).

Jacquemyn H, Merckx V, Brys R, Tyteca D, Cammue BP, Honnay O, Lievens B.

New Phytol. 2011 Oct;192(2):518-28. doi: 10.1111/j.1469-8137.2011.03796.x. Epub 2011 Jun 13.

41.

Variation in the functioning of autonomous self-pollination, pollinator services and floral traits in three Centaurium species.

Brys R, Jacquemyn H.

Ann Bot. 2011 May;107(6):917-25. doi: 10.1093/aob/mcr032. Epub 2011 Feb 13.

42.

Mycorrhizal associations and reproductive isolation in three closely related Orchis species.

Jacquemyn H, Brys R, Cammue BP, Honnay O, Lievens B.

Ann Bot. 2011 Mar;107(3):347-56. doi: 10.1093/aob/mcq248. Epub 2010 Dec 24.

43.

Impact of herbivory on flowering behaviour and life history trade-offs in a polycarpic herb: a 10-year experiment.

Brys R, Shefferson RP, Jacquemyn H.

Oecologia. 2011 Jun;166(2):293-303. doi: 10.1007/s00442-010-1842-7. Epub 2010 Dec 1.

PMID:
21120670
44.

Low specificity and nested subset structure characterize mycorrhizal associations in five closely related species of the genus Orchis.

Jacquemyn H, Honnay O, Cammue BP, Brys R, Lievens B.

Mol Ecol. 2010 Sep;19(18):4086-95. doi: 10.1111/j.1365-294X.2010.04785.x. Epub 2010 Aug 23.

PMID:
20735736
45.

A multiparameter approach to monitor disease activity in collagen-induced arthritis.

Seeuws S, Jacques P, Van Praet J, Drennan M, Coudenys J, Decruy T, Deschepper E, Lepescheux L, Pujuguet P, Oste L, Vandeghinste N, Brys R, Verbruggen G, Elewaut D.

Arthritis Res Ther. 2010;12(4):R160. doi: 10.1186/ar3119. Epub 2010 Aug 23.

46.

Temporal and spatial variation in flower and fruit production in a food-deceptive orchid: a five-year study.

Jacquemyn H, Brys R.

Plant Biol (Stuttg). 2010 Jan;12(1):145-53. doi: 10.1111/j.1438-8677.2009.00217.x.

PMID:
20653897
47.
48.

Seed limitation restricts population growth in shaded populations of a perennial woodland orchid.

Jacquemyn H, Brys R, Jongejans E.

Ecology. 2010 Jan;91(1):119-29.

PMID:
20380202
49.

Large population sizes mitigate negative effects of variable weather conditions on fruit set in two spring woodland orchids.

Jacquemyn H, Brys R, Honnay O.

Biol Lett. 2009 Aug 23;5(4):495-8. doi: 10.1098/rsbl.2009.0262. Epub 2009 May 20.

50.

The alpha7 nicotinic acetylcholine receptor on fibroblast-like synoviocytes and in synovial tissue from rheumatoid arthritis patients: a possible role for a key neurotransmitter in synovial inflammation.

van Maanen MA, Stoof SP, van der Zanden EP, de Jonge WJ, Janssen RA, Fischer DF, Vandeghinste N, Brys R, Vervoordeldonk MJ, Tak PP.

Arthritis Rheum. 2009 May;60(5):1272-81. doi: 10.1002/art.24470.

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