Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 90


Should we Try to Alleviate Immunosenescence and Inflammaging - Why, How and to What Extent?

Witkowski JM, Bryl E, Fulop T.

Curr Pharm Des. 2019;25(39):4154-4162. doi: 10.2174/1381612825666191111153016.


Chemical variability of Rhododendron tomentosum (Ledum palustre) essential oils and their pro-apoptotic effect on lymphocytes and rheumatoid arthritis synoviocytes.

Jesionek A, Kokotkiewicz A, Mikosik-Roczynska A, Ciesielska-Figlon K, Luczkiewicz P, Bucinski A, Daca A, Witkowski JM, Bryl E, Zabiegala B, Luczkiewicz M.

Fitoterapia. 2019 Nov;139:104402. doi: 10.1016/j.fitote.2019.104402. Epub 2019 Oct 28.


Abnormal body weight and food-related behavior in school-aged children as measured by the Children's Binge Eating Disorder Scale.

Dmitrzak-Węglarz M, Tyszkiewicz-Nwafor M, Duda J, Paszyńska E, Matuszak-Wojciechowska L, Hanć T, Bryl E, Mamrot P, Dutkiewicz A, Słopień A.

Clin Child Psychol Psychiatry. 2019 Sep 18:1359104519871335. doi: 10.1177/1359104519871335. [Epub ahead of print]


Proliferation rate and penicillin binding of enterococcal isolates from patients with immunosupression.

Jarzembowski TA, Daca AE, Witkowski JM, Bryl ED.

Lett Appl Microbiol. 2019 Jul;69(1):30-34. doi: 10.1111/lam.13161. Epub 2019 Jun 7.


Meeting Report: The Role of Beliefs and Perception on Body Size. Proceedings of the 26th Aschauer Soiree, Held at Aschauhof, Altenhof, Germany, May 26th, 2018.

Hermanussen M, Pulungan AB, Scheffler C, Mumm R, Rogol AD, Pop R, Swanson JM, Sonuga-Barke E, Reimann A, Siniarska-Wolanska A, Musalek M, Bogin B, Boldsen JL, Tassenaar PGV, Groth D, Liu YC, Meigen C, Quanjer B, Thompson K, Özer BK, Bryl E, Mamrot P, Hanć T, Koziel S, Söderhäll J, Gomula A, Banik SD, Roelants M, Veldre G, Lieberman LS, Sievert LL.

Pediatr Endocrinol Rev. 2019 Mar;16(3):383-400. doi: 10.17458/


Immunological aspects of autoimmune thyroid disease - Complex interplay between cells and cytokines.

Luty J, Ruckemann-Dziurdzińska K, Witkowski JM, Bryl E.

Cytokine. 2019 Apr;116:128-133. doi: 10.1016/j.cyto.2019.01.003. Epub 2019 Feb 1. Review.


Autoantibodies, C-reactive protein, erythrocyte sedimentation rate and serum cytokine profiling in monitoring of early treatment.

Brzustewicz E, Henc I, Daca A, Szarecka M, Sochocka-Bykowska M, Witkowski J, Bryl E.

Cent Eur J Immunol. 2017;42(3):259-268. doi: 10.5114/ceji.2017.70968. Epub 2017 Oct 30.


Vitamin D status in patients with rheumatoid arthritis: a correlation analysis with disease activity and progression, as well as serum IL-6 levels.

Polasik K, Piotrowska E, Lipińska B, Witkowski JM, Bryl E, Tukaj S.

Acta Biochim Pol. 2017;64(4):667-670. doi: 10.18388/abp.2017_1636. Epub 2017 Dec 5.


Proteodynamics in aging human T cells - The need for its comprehensive study to understand the fine regulation of T lymphocyte functions.

Witkowski JM, Mikosik A, Bryl E, Fulop T.

Exp Gerontol. 2018 Jul 1;107:161-168. doi: 10.1016/j.exger.2017.10.009. Epub 2017 Oct 13. Review.


The role of vitamin D in the development of autoimmune diseases.

Lisowska KA, Bryl E.

Postepy Hig Med Dosw (Online). 2017 Aug 28;71(1):797-810.


Naturally occurring xanthone and benzophenone derivatives exert significant anti-proliferative and proapoptotic effects in vitro on synovial fibroblasts and macrophages from rheumatoid arthritis patients.

Henc I, Kokotkiewicz A, Łuczkiewicz P, Bryl E, Łuczkiewicz M, Witkowski JM.

Int Immunopharmacol. 2017 Aug;49:148-154. doi: 10.1016/j.intimp.2017.05.034. Epub 2017 Jun 3.


Heterogeneity of the cytokinome in undifferentiated arthritis progressing to rheumatoid arthritis and its change in the course of therapy. Move toward personalized medicine.

Brzustewicz E, Bzoma I, Daca A, Szarecka M, Bykowska MS, Witkowski JM, Bryl E.

Cytokine. 2017 Sep;97:1-13. doi: 10.1016/j.cyto.2017.05.012. Epub 2017 May 25.


Influence of oxygen concentration on T cell proliferation and susceptibility to apoptosis in healthy men and women.

Waskowska A, Lisowska KA, Daca A, Henc I, Brandberg F, Mazurek P, Brzustewicz E, Witkowski JM, Bryl E.

Folia Histochem Cytobiol. 2017;55(1):26-36. doi: 10.5603/FHC.a2017.0006.


Roles of calpain-calpastatin system (CCS) in human T cell activation.

Mikosik A, Jasiulewicz A, Daca A, Henc I, Frąckowiak JE, Ruckemann-Dziurdzińska K, Foerster J, Le Page A, Bryl E, Fulop T, Witkowski JM.

Oncotarget. 2016 Nov 22;7(47):76479-76495. doi: 10.18632/oncotarget.13259.


The role of cytokines in the pathogenesis of rheumatoid arthritis--Practical and potential application of cytokines as biomarkers and targets of personalized therapy.

Brzustewicz E, Bryl E.

Cytokine. 2015 Dec;76(2):527-536. doi: 10.1016/j.cyto.2015.08.260. Epub 2015 Aug 29. Review.


Increased μ-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis.

Mikosik A, Henc I, Ruckemann-Dziurdzińska K, Frąckowiak JE, Płoszyńska A, Balcerska A, Bryl E, Witkowski JM.

PLoS One. 2015 Aug 28;10(8):e0136615. doi: 10.1371/journal.pone.0136615. eCollection 2015. Erratum in: PLoS One. 2015;10(9):e0139063.


The high PMNs phagocytosis resistance of enterococcal isolates from RTx patients.

Jarzembowski T, Daca A, Witkowski JM, Bryl E, Rutkowski B.

Biomed Res Int. 2015;2015:432579. doi: 10.1155/2015/432579. Epub 2015 Mar 10.


The in vitro modulatory effect of TNFα on the mRNA expression and protein levels of zinc finger protein ZNF334 in CD4(+) lymphocytes of healthy people.

Henc I, Soroczyńska-Cybula M, Bryl E, Witkowski JM.

Acta Biochim Pol. 2015;62(1):113-7. Epub 2015 Mar 4.


Prophages in enterococcal isolates from renal transplant recipients: renal failure etiologies promote selection of strains.

Daca A, Jarzembowski T, Witkowski JM, Bryl E, Rutkowski B, Dębska-Ślizień A.

Biomed Res Int. 2014;2014:514689. doi: 10.1155/2014/514689. Epub 2014 Jul 3.


Different pattern of T-cell subpopulations in peripheral blood of patients with rheumatoid arthritis at various stages of disease development.

Pawłowska J, Smoleńska Ż, Witkowski J, Bryl EM.

Pol Arch Med Wewn. 2014;124(1-2):43-50. Epub 2013 Nov 15.


Influence of hemodialysis on circulating CD4(low)CD25 (high) regulatory T cells in end-stage renal disease patients.

Lisowska KA, Dębska-Ślizień A, Jasiulewicz A, Bryl E, Witkowski JM.

Inflamm Res. 2014 Feb;63(2):99-103. doi: 10.1007/s00011-013-0679-z. Epub 2013 Nov 5.


Complex interaction between the immune system and adipose tissue (Review).

Małgorzewicz S, Dardzińska JA, Gnacińska M, Jankun J, Bryl E, Sworczak K.

Int J Mol Med. 2014 Jan;33(1):3-7. doi: 10.3892/ijmm.2013.1537. Epub 2013 Oct 25. Review.


Isolation of xanthone and benzophenone derivatives from Cyclopia genistoides (L.) Vent. (honeybush) and their pro-apoptotic activity on synoviocytes from patients with rheumatoid arthritis.

Kokotkiewicz A, Luczkiewicz M, Pawlowska J, Luczkiewicz P, Sowinski P, Witkowski J, Bryl E, Bucinski A.

Fitoterapia. 2013 Oct;90:199-208. doi: 10.1016/j.fitote.2013.07.020. Epub 2013 Aug 3.


Expression of calpain-calpastatin system (CCS) member proteins in human lymphocytes of young and elderly individuals; pilot baseline data for the CALPACENT project.

Mikosik A, Foerster J, Jasiulewicz A, Frąckowiak J, Colonna-Romano G, Bulati M, Buffa S, Martorana A, Caruso C, Bryl E, Witkowski JM.

Immun Ageing. 2013 Jul 8;10(1):27. doi: 10.1186/1742-4933-10-27.


The influence of recombinant human erythropoietin on apoptosis and cytokine production of CD4+ lymphocytes from hemodialyzed patients.

Lisowska KA, Dębska-Ślizień A, Jasiulewicz A, Daca A, Bryl E, Witkowski JM.

J Clin Immunol. 2013 Apr;33(3):661-5. doi: 10.1007/s10875-012-9835-4. Epub 2012 Nov 20.


Disease activity in patients with long-lasting rheumatoid arthritis is associated with changes in peripheral blood lymphocyte subpopulations.

Smoleńska Ż, Pawłowska J, Daca A, Soroczyńska-Cybula M, Witkowski J, Bryl EM.

Pol Arch Med Wewn. 2012;122(12):591-8. Epub 2012 Nov 20.


Increased percentage of CD8+CD28- T cells correlates with clinical activity in primary Sjögren's syndrome.

Smoleńska Z, Pawłowska J, Zdrojewski Z, Daca A, Bryl E.

Cell Immunol. 2012 Jul-Aug;278(1-2):143-51. doi: 10.1016/j.cellimm.2012.08.001. Epub 2012 Aug 23.


Increased pheromone cCF10 expression in Enterococcus faecalis biofilm formed by isolates from renal transplant patients.

Jarzembowski T, Daca A, Bryl E, Wiśniewska K, Gołębiewska J, Dębska-Ślizień A, Rutkowski B, Witkowski J.

Curr Microbiol. 2012 Dec;65(6):656-9. doi: 10.1007/s00284-012-0202-8. Epub 2012 Aug 21.


Changes in proliferation kinetics of T cells: a new predictive cellular biomarkers for early rheumatoid arthritis?

Pawłowska J, Smoleńska Ż, Zdrojewski Z, Witkowski JM, Bryl E.

J Clin Immunol. 2012 Oct;32(5):991-9. doi: 10.1007/s10875-012-9692-1. Epub 2012 Apr 25.


Beta-amyloid peptides enhance the proliferative response of activated CD4CD28 lymphocytes from Alzheimer disease patients and from healthy elderly.

Jóźwik A, Landowski J, Bidzan L, Fülop T, Bryl E, Witkowski JM.

PLoS One. 2012;7(3):e33276. doi: 10.1371/journal.pone.0033276. Epub 2012 Mar 12.


Hemodialysis affects phenotype and proliferation of CD4-positive T lymphocytes.

Lisowska KA, Dębska-Ślizień A, Jasiulewicz A, Heleniak Z, Bryl E, Witkowski JM.

J Clin Immunol. 2012 Feb;32(1):189-200. doi: 10.1007/s10875-011-9603-x. Epub 2011 Oct 13.


Two systemic lupus erythematosus (SLE) global disease activity indexes--the SLE Disease Activity Index and the Systemic Lupus Activity Measure--demonstrate different correlations with activation of peripheral blood CD4+ T cells.

Daca A, Czuszyńska Z, Smoleńska Z, Zdrojewski Z, Witkowski JM, Bryl E.

Hum Immunol. 2011 Dec;72(12):1160-7. doi: 10.1016/j.humimm.2011.08.005. Epub 2011 Aug 26.


Flow cytometric analysis of STAT5 phosphorylation and CD95 expression in CD4+ T lymphocytes treated with recombinant human erythropoietin.

Lisowska KA, Dębska-Ślizień A, Jasiulewicz A, Jóźwik A, Rutkowski B, Bryl E, Witkowski JM.

J Recept Signal Transduct Res. 2011 Jun;31(3):241-6. doi: 10.3109/10799893.2011.578646.


Erythropoietin receptor is detectable on peripheral blood lymphocytes and its expression increases in activated T lymphocytes.

Lisowska KA, Bryl E, Witkowski JM.

Haematologica. 2011 Mar;96(3):e12-3; author reply e14. doi: 10.3324/haematol.2010.038414. No abstract available.


Older age of rheumatoid arthritis onset is associated with higher activation status of peripheral blood CD4(+) T cells and disease activity.

Pawłowska J, Smoleńska Z, Daca A, Witkowski JM, Bryl E.

Clin Exp Immunol. 2011 Feb;163(2):157-64. doi: 10.1111/j.1365-2249.2010.04294.x. Epub 2010 Dec 13.


Cytokines of the Th1 and Th2 type in sera of rheumatoid arthritis patients; correlations with anti-Hsp40 immune response and diagnostic markers.

Tukaj S, Kotlarz A, Jóźwik A, Smoleńska Z, Bryl E, Witkowski JM, Lipińska B.

Acta Biochim Pol. 2010;57(3):327-32. Epub 2010 Sep 9.


Varying expression of four genes sharing a common regulatory sequence may differentiate rheumatoid arthritis from ageing effects on the CD4(+) lymphocytes.

Soroczyńska-Cybula M, Bryl E, Smoleńska Z, Witkowski JM.

Immunology. 2011 Jan;132(1):78-86. doi: 10.1111/j.1365-2567.2010.03341.x. Epub 2010 Aug 25.


Erythropoietin receptor is expressed on human peripheral blood T and B lymphocytes and monocytes and is modulated by recombinant human erythropoietin treatment.

Lisowska KA, Debska-Slizień A, Bryl E, Rutkowski B, Witkowski JM.

Artif Organs. 2010 Aug;34(8):654-62. doi: 10.1111/j.1525-1594.2009.00948.x. Epub 2010 May 31.


Recombinant human erythropoietin treatment of chronic renal failure patients normalizes altered phenotype and proliferation of CD4-positive T lymphocytes.

Lisowska KA, Debska-Slizien A, Radzka M, Witkowski JM, Rutkowski B, Bryl E.

Artif Organs. 2010 Mar;34(3):E77-84. doi: 10.1111/j.1525-1594.2009.00942.x.


Hsp40 proteins modulate humoral and cellular immune response in rheumatoid arthritis patients.

Tukaj S, Kotlarz A, Jozwik A, Smolenska Z, Bryl E, Witkowski JM, Lipinska B.

Cell Stress Chaperones. 2010 Sep;15(5):555-66. doi: 10.1007/s12192-010-0168-z. Epub 2010 Feb 2.


Expression of Hsp72 protein in chronic kidney disease patients.

Marzec L, Zdrojewski Z, Liberek T, Bryl E, Chmielewski M, Witkowski JM, Rutkowski B.

Scand J Urol Nephrol. 2009;43(5):400-8. doi: 10.3109/00365590903089489.


P-glycoprotein activity predicts outcome in childhood acute lymphoblastic leukemia.

Brozek J, Bryl E, Płoszyńska A, Balcerska A, Witkowski JM.

J Pediatr Hematol Oncol. 2009 Jul;31(7):493-9. doi: 10.1097/MPH.0b013e3181a974b3.


Cytoprotective effect of lithium against spontaneous and induced apoptosis of lymphoid cell line MOLT-4.

Pietruczuk K, Jóźwik A, Ruckemann-Dziurdzińska K, Bryl E, Witkowski JM.

Folia Histochem Cytobiol. 2009;47(4):639-46. doi: 10.2478/v10042-009-0118-8.


Different distribution of CD4 and CD8 T cells in synovial membrane and peripheral blood of rheumatoid arthritis and osteoarthritis patients.

Pawłowska J, Mikosik A, Soroczynska-Cybula M, Jóźwik A, Łuczkiewicz P, Mazurkiewicz S, Lorczyński A, Witkowski JM, Bryl E.

Folia Histochem Cytobiol. 2009;47(4):627-32. doi: 10.2478/v10042-009-0117-9.


Human CD4low CD25high regulatory T cells indiscriminately kill autologous activated T cells.

Bryl E, Daca A, Jóźwik A, Witkowski JM.

Immunology. 2009 Sep;128(1 Suppl):e287-95. doi: 10.1111/j.1365-2567.2008.02961.x. Epub 2008 Nov 7.


Flow cytometry as a rapid test for detection of penicillin resistance directly in bacterial cells in Enterococcus faecalis and Staphylococcus aureus.

Jarzembowski T, Wiśniewska K, Józwik A, Bryl E, Witkowski J.

Curr Microbiol. 2008 Aug;57(2):167-9. doi: 10.1007/s00284-008-9179-8. Epub 2008 Jun 24.


Ex vivo measurement of calpain activation in human peripheral blood lymphocytes by detection of immunoreactive products of calpastatin degradation.

Mikosik A, Zaremba A, Puchalska Z, Daca A, Smolenska Z, Lopatniuk P, Mital A, Hellman A, Bryl E, Witkowski JM.

Folia Histochem Cytobiol. 2007;45(4):343-7.


Expression of heat shock protein 72 in peritoneal leukocytes is induced by peritoneal dialysis.

Marzec L, Liberek T, Chmielewski M, Bryl E, Witkowski JM, Liberek K, Zdrojewski Z, Rutkowski B.

Perit Dial Int. 2007 May-Jun;27(3):288-95.


The activity of caspases in spontaneous and camptothecin-induced death of melanotic and amelanotic melanoma cell.

Cichorek M, Kozłowska K, Bryl E.

Cancer Biol Ther. 2007 Mar;6(3):346-53. Epub 2007 Mar 12.


Supplemental Content

Support Center