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Items: 1 to 50 of 63

1.

The deubiquitinating enzyme USP25 binds tankyrase and regulates trafficking of the facilitative glucose transporter GLUT4 in adipocytes.

Sadler JBA, Lamb CA, Welburn CR, Adamson IS, Kioumourtzoglou D, Chi NW, Gould GW, Bryant NJ.

Sci Rep. 2019 Mar 18;9(1):4710. doi: 10.1038/s41598-019-40596-5.

2.

Rabies in a Dog Imported from Egypt - Connecticut, 2017.

Hercules Y, Bryant NJ, Wallace RM, Nelson R, Palumbo G, Williams JN, Ocana JM, Shapiro S, Leavitt H, Slavinsk S, Newman A, Crum DA, Joseph BE, Orciari LA, Li Y, Yager P, Condori RE, Stauffer KE, Brown C.

MMWR Morb Mortal Wkly Rep. 2018 Dec 21;67(50):1388-1391. doi: 10.15585/mmwr.mm6750a3.

3.

Proximity Ligation Assay to Study the GLUT4 Membrane Trafficking Machinery.

Kioumourtzoglou D, Gould GW, Bryant NJ.

Methods Mol Biol. 2018;1713:217-227. doi: 10.1007/978-1-4939-7507-5_16.

PMID:
29218528
4.

SNARE phosphorylation: a control mechanism for insulin-stimulated glucose transport and other regulated exocytic events.

Laidlaw KME, Livingstone R, Al-Tobi M, Bryant NJ, Gould GW.

Biochem Soc Trans. 2017 Dec 15;45(6):1271-1277. doi: 10.1042/BST20170202. Epub 2017 Nov 3. Review.

PMID:
29101310
5.

16K Fractionation of 3T3-L1 Adipocytes to Produce a Crude GLUT4-Containing Vesicle Fraction.

Sadler JB, Lamb CA, Gould GW, Bryant NJ.

Cold Spring Harb Protoc. 2016 Mar 1;2016(3):pdb.prot083683. doi: 10.1101/pdb.prot083683.

PMID:
26933244
6.

Preparation of a Total Membrane Fraction from 3T3-L1 Adipocytes.

Sadler JB, Lamb CA, Gould GW, Bryant NJ.

Cold Spring Harb Protoc. 2016 Mar 1;2016(3):pdb.prot083675. doi: 10.1101/pdb.prot083675.

PMID:
26933243
7.

Iodixanol Gradient Centrifugation to Separate Components of the Low-Density Membrane Fraction from 3T3-L1 Adipocytes.

Sadler JB, Lamb CA, Gould GW, Bryant NJ.

Cold Spring Harb Protoc. 2016 Feb 1;2016(2):pdb.prot083709. doi: 10.1101/pdb.prot083709.

PMID:
26832683
8.

Complete Membrane Fractionation of 3T3-L1 Adipocytes.

Sadler JB, Lamb CA, Gould GW, Bryant NJ.

Cold Spring Harb Protoc. 2016 Feb 1;2016(2):pdb.prot083691. doi: 10.1101/pdb.prot083691.

PMID:
26832682
9.

mVps45 knockdown selectively modulates VAMP expression in 3T3-L1 adipocytes.

Sadler JB, Roccisana J, Virolainen M, Bryant NJ, Gould GW.

Commun Integr Biol. 2015 Jun 24;8(3):e1026494. doi: 10.1080/19420889.2015.1026494. eCollection 2015 May-Jun.

10.

Alternative routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4.

Kioumourtzoglou D, Pryor PR, Gould GW, Bryant NJ.

J Cell Sci. 2015 Jul 15;128(14):2423-9. doi: 10.1242/jcs.166561. Epub 2015 Jun 12.

11.

Characterization of VAMP isoforms in 3T3-L1 adipocytes: implications for GLUT4 trafficking.

Sadler JB, Bryant NJ, Gould GW.

Mol Biol Cell. 2015 Feb 1;26(3):530-6. doi: 10.1091/mbc.E14-09-1368. Epub 2014 Dec 10.

12.

Studies of the regulated assembly of SNARE complexes in adipocytes.

Kioumourtzoglou D, Sadler JB, Black HL, Berends R, Wellburn C, Bryant NJ, Gould GW.

Biochem Soc Trans. 2014 Oct;42(5):1396-400. doi: 10.1042/BST20140114. Review.

PMID:
25233421
13.

Insulin stimulates syntaxin4 SNARE complex assembly via a novel regulatory mechanism.

Kioumourtzoglou D, Gould GW, Bryant NJ.

Mol Cell Biol. 2014 Apr;34(7):1271-9. doi: 10.1128/MCB.01203-13. Epub 2014 Jan 27.

14.

Homotypic vacuole fusion in yeast requires organelle acidification and not the V-ATPase membrane domain.

Coonrod EM, Graham LA, Carpp LN, Carr TM, Stirrat L, Bowers K, Bryant NJ, Stevens TH.

Dev Cell. 2013 Nov 25;27(4):462-8. doi: 10.1016/j.devcel.2013.10.014.

15.

Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45.

Roccisana J, Sadler JB, Bryant NJ, Gould GW.

Mol Biol Cell. 2013 Aug;24(15):2389-97. doi: 10.1091/mbc.E13-01-0011. Epub 2013 Jun 5.

16.

Posttranslational modifications of GLUT4 affect its subcellular localization and translocation.

Sadler JB, Bryant NJ, Gould GW, Welburn CR.

Int J Mol Sci. 2013 May 10;14(5):9963-78. doi: 10.3390/ijms14059963. Review.

17.

The Thr224Asn mutation in the VPS45 gene is associated with the congenital neutropenia and primary myelofibrosis of infancy.

Stepensky P, Saada A, Cowan M, Tabib A, Fischer U, Berkun Y, Saleh H, Simanovsky N, Kogot-Levin A, Weintraub M, Ganaiem H, Shaag A, Zenvirt S, Borkhardt A, Elpeleg O, Bryant NJ, Mevorach D.

Blood. 2013 Jun 20;121(25):5078-87. doi: 10.1182/blood-2012-12-475566. Epub 2013 Apr 18.

18.

Arabidopsis Sec1/Munc18 protein SEC11 is a competitive and dynamic modulator of SNARE binding and SYP121-dependent vesicle traffic.

Karnik R, Grefen C, Bayne R, Honsbein A, Köhler T, Kioumourtzoglou D, Williams M, Bryant NJ, Blatt MR.

Plant Cell. 2013 Apr;25(4):1368-82. doi: 10.1105/tpc.112.108506. Epub 2013 Apr 9.

19.

Endosomal sorting of GLUT4 and Gap1 is conserved between yeast and insulin-sensitive cells.

Shewan AM, McCann RK, Lamb CA, Stirrat L, Kioumourtzoglou D, Adamson IS, Verma S, James DE, Bryant NJ.

J Cell Sci. 2013 Apr 1;126(Pt 7):1576-82. doi: 10.1242/jcs.114371. Epub 2013 Feb 19.

20.

The Sec1/Munc18 protein Vps45 regulates cellular levels of its SNARE binding partners Tlg2 and Snc2 in Saccharomyces cerevisiae.

Shanks SG, Carpp LN, Struthers MS, McCann RK, Bryant NJ.

PLoS One. 2012;7(11):e49628. doi: 10.1371/journal.pone.0049628. Epub 2012 Nov 14.

21.

Herpes simplex serious neurological disease in young children: incidence and long-term outcome.

Ward KN, Ohrling A, Bryant NJ, Bowley JS, Ross EM, Verity CM.

Arch Dis Child. 2012 Feb;97(2):162-5. doi: 10.1136/adc.2010.204677. Epub 2011 Jun 17.

22.

Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4.

Aran V, Bryant NJ, Gould GW.

BMC Biochem. 2011 May 6;12:19. doi: 10.1186/1471-2091-12-19.

23.

BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation.

Wiggins CM, Tsvetkov P, Johnson M, Joyce CL, Lamb CA, Bryant NJ, Komander D, Shaul Y, Cook SJ.

J Cell Sci. 2011 Mar 15;124(Pt 6):969-77. doi: 10.1242/jcs.058438.

24.

SNARE proteins underpin insulin-regulated GLUT4 traffic.

Bryant NJ, Gould GW.

Traffic. 2011 Jun;12(6):657-64. doi: 10.1111/j.1600-0854.2011.01163.x. Epub 2011 Feb 8. Review.

25.

Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13.

Jenkins L, Brea J, Smith NJ, Hudson BD, Reilly G, Bryant NJ, Castro M, Loza MI, Milligan G.

Biochem J. 2010 Dec 15;432(3):451-9. doi: 10.1042/BJ20101287.

PMID:
20919992
26.

Insulin-regulated trafficking of GLUT4 requires ubiquitination.

Lamb CA, McCann RK, Stöckli J, James DE, Bryant NJ.

Traffic. 2010 Nov;11(11):1445-54. doi: 10.1111/j.1600-0854.2010.01113.x. Epub 2010 Sep 20.

27.

Autoinhibition of SNARE complex assembly by a conformational switch represents a conserved feature of syntaxins.

MacDonald C, Munson M, Bryant NJ.

Biochem Soc Trans. 2010 Feb;38(Pt 1):209-12. doi: 10.1042/BST0380209.

28.

The N-terminal peptide of the syntaxin Tlg2p modulates binding of its closed conformation to Vps45p.

Furgason ML, MacDonald C, Shanks SG, Ryder SP, Bryant NJ, Munson M.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14303-8. doi: 10.1073/pnas.0902976106. Epub 2009 Aug 10.

29.

Functional homology of mammalian syntaxin 16 and yeast Tlg2p reveals a conserved regulatory mechanism.

Struthers MS, Shanks SG, MacDonald C, Carpp LN, Drozdowska AM, Kioumourtzoglou D, Furgason ML, Munson M, Bryant NJ.

J Cell Sci. 2009 Jul 1;122(Pt 13):2292-9. doi: 10.1242/jcs.046441. Epub 2009 Jun 9.

30.

Characterization of two distinct binding modes between syntaxin 4 and Munc18c.

Aran V, Brandie FM, Boyd AR, Kantidakis T, Rideout EJ, Kelly SM, Gould GW, Bryant NJ.

Biochem J. 2009 May 1;419(3):655-60. doi: 10.1042/BJ20082293.

PMID:
19193195
31.

A role for the syntaxin N-terminus.

Munson M, Bryant NJ.

Biochem J. 2009 Feb 15;418(1):e1-3. doi: 10.1042/BJ20082389.

32.

Negative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c in vitro.

Brandie FM, Aran V, Verma A, McNew JA, Bryant NJ, Gould GW.

PLoS One. 2008;3(12):e4074. doi: 10.1371/journal.pone.0004074. Epub 2008 Dec 31.

33.

Cellular levels of the syntaxin Tlg2p are regulated by a single mode of binding to Vps45p.

Carpp LN, Shanks SG, Struthers MS, Bryant NJ.

Biochem Biophys Res Commun. 2007 Nov 23;363(3):857-60. Epub 2007 Sep 25.

PMID:
17904527
34.

Risk of serious neurologic disease after immunization of young children in Britain and Ireland.

Ward KN, Bryant NJ, Andrews NJ, Bowley JS, Ohrling A, Verity CM, Ross EM, Miller E.

Pediatrics. 2007 Aug;120(2):314-21.

PMID:
17671057
35.

Scrub typhus serologic testing with the indirect immunofluorescence method as a diagnostic gold standard: a lack of consensus leads to a lot of confusion.

Blacksell SD, Bryant NJ, Paris DH, Doust JA, Sakoda Y, Day NP.

Clin Infect Dis. 2007 Feb 1;44(3):391-401. Epub 2007 Jan 3. Review.

PMID:
17205447
36.

Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking.

Latham CF, Lopez JA, Hu SH, Gee CL, Westbury E, Blair DH, Armishaw CJ, Alewood PF, Bryant NJ, James DE, Martin JL.

Traffic. 2006 Oct;7(10):1408-19. Epub 2006 Aug 10.

37.

Tolerance of local anesthetic for transrectal ultrasound-guided prostate biopsy: our experience and a literature review.

Buckley MR, Bryant NJ, Brown JA, Tiwari P, Cooperberg PL, Wong AD.

Can Assoc Radiol J. 2006 Jun;57(3):169-74. Review.

PMID:
16881474
38.

Syntaxin 16 controls the intracellular sequestration of GLUT4 in 3T3-L1 adipocytes.

Proctor KM, Miller SC, Bryant NJ, Gould GW.

Biochem Biophys Res Commun. 2006 Aug 25;347(2):433-8. Epub 2006 Jun 30.

PMID:
16828707
39.

The Sec1p/Munc18 protein Vps45p binds its cognate SNARE proteins via two distinct modes.

Carpp LN, Ciufo LF, Shanks SG, Boyd A, Bryant NJ.

J Cell Biol. 2006 Jun 19;173(6):927-36. Epub 2006 Jun 12.

40.

Exercise-induced stridor due to abnormal movement of the arytenoid area: videoendoscopic diagnosis and characterization of the "at risk" group.

Fahey JT, Bryant NJ, Karas D, Goldberg B, Destefano R, Gracco LC.

Pediatr Pulmonol. 2005 Jan;39(1):51-5.

PMID:
15558600
41.

Recombinant expression of Munc18c in a baculovirus system and interaction with syntaxin4.

Hu SH, Gee CL, Latham CF, Rowlinson SW, Rova U, Jones A, Halliday JA, Bryant NJ, James DE, Martin JL.

Protein Expr Purif. 2003 Oct;31(2):305-10.

PMID:
14550652
42.

Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation.

Widberg CH, Bryant NJ, Girotti M, Rea S, James DE.

J Biol Chem. 2003 Sep 12;278(37):35093-101. Epub 2003 Jun 27.

43.

The Sec1p/Munc18 (SM) protein, Vps45p, cycles on and off membranes during vesicle transport.

Bryant NJ, James DE.

J Cell Biol. 2003 May 26;161(4):691-6. Epub 2003 May 19. Erratum in: J Cell Biol. 2012 Nov 26;199(5):863.

44.

GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in Syntaxins 6 and 16 but not TGN38: involvement of an acidic targeting motif.

Shewan AM, van Dam EM, Martin S, Luen TB, Hong W, Bryant NJ, James DE.

Mol Biol Cell. 2003 Mar;14(3):973-86.

45.

The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion.

Pagan JK, Wylie FG, Joseph S, Widberg C, Bryant NJ, James DE, Stow JL.

Curr Biol. 2003 Jan 21;13(2):156-60.

46.

Regulated transport of the glucose transporter GLUT4.

Bryant NJ, Govers R, James DE.

Nat Rev Mol Cell Biol. 2002 Apr;3(4):267-77. Review.

PMID:
11994746
47.

Balloon cell melanoma in three dogs: a histopathological, immunohistochemical and ultrastructural study.

Blanchard TW, Bryant NJ, Mense MG.

J Comp Pathol. 2001 Nov;125(4):254-61.

PMID:
11798242
48.
49.

Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells.

Wade N, Bryant NJ, Connolly LM, Simpson RJ, Luzio JP, Piper RC, James DE.

J Biol Chem. 2001 Jun 8;276(23):19820-7. Epub 2001 Mar 1.

50.

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells.

Gillooly DJ, Morrow IC, Lindsay M, Gould R, Bryant NJ, Gaullier JM, Parton RG, Stenmark H.

EMBO J. 2000 Sep 1;19(17):4577-88.

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