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Items: 1 to 50 of 113

1.

A comprehensive UHPLC ion mobility QTOF method for profiling and quantification of eicosanoids, other oxylipins and fatty acids.

Hinz C, Liggi S, Mocciaro G, Jung SM, Induruwa I, Pereira MCDA, Bryant CE, Meckelmann SW, O'Donnell VB, Farndale RW, Fjeldsted JC, Griffin JL.

Anal Chem. 2019 May 10. doi: 10.1021/acs.analchem.8b04615. [Epub ahead of print]

PMID:
31074960
2.

Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4.

Pizzuto M, Lonez C, Baroja-Mazo A, Martínez-Banaclocha H, Tourlomousis P, Gangloff M, Pelegrin P, Ruysschaert JM, Gay NJ, Bryant CE.

Cell Mol Life Sci. 2019 May 6. doi: 10.1007/s00018-019-03113-5. [Epub ahead of print]

PMID:
31062071
3.

Chopping GSDMD: caspase-8 has joined the team of pyroptosis-mediating caspases.

Gram AM, Booty LM, Bryant CE.

EMBO J. 2019 May 15;38(10). pii: e102065. doi: 10.15252/embj.2019102065. Epub 2019 Apr 15. No abstract available.

4.

Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.

Castro-Dopico T, Dennison TW, Ferdinand JR, Mathews RJ, Fleming A, Clift D, Stewart BJ, Jing C, Strongili K, Labzin LI, Monk EJM, Saeb-Parsy K, Bryant CE, Clare S, Parkes M, Clatworthy MR.

Immunity. 2019 Apr 16;50(4):1099-1114.e10. doi: 10.1016/j.immuni.2019.02.006. Epub 2019 Mar 12.

5.

A blood dendritic cell vaccine for acute myeloid leukemia expands anti-tumor T cell responses at remission.

Hsu JL, Bryant CE, Papadimitrious MS, Kong B, Gasiorowski RE, Orellana D, McGuire HM, Groth BFS, Joshua DE, Ho PJ, Larsen S, Iland HJ, Gibson J, Clark GJ, Fromm PD, Hart DN.

Oncoimmunology. 2018 Jan 25;7(4):e1419114. doi: 10.1080/2162402X.2017.1419114. eCollection 2018.

6.

Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons.

Ritchie L, Tate R, Chamberlain LH, Robertson G, Zagnoni M, Sposito T, Wray S, Wright JA, Bryant CE, Gay NJ, Bushell TJ.

Neuropharmacology. 2018 Jun;135:1-10. doi: 10.1016/j.neuropharm.2018.02.025. Epub 2018 Mar 2.

7.

Dendritic cells as cancer therapeutics.

Bryant CE, Sutherland S, Kong B, Papadimitrious MS, Fromm PD, Hart DNJ.

Semin Cell Dev Biol. 2019 Feb;86:77-88. doi: 10.1016/j.semcdb.2018.02.015. Epub 2018 Mar 21. Review.

PMID:
29454038
8.

Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub.

Latty SL, Sakai J, Hopkins L, Verstak B, Paramo T, Berglund NA, Cammarota E, Cicuta P, Gay NJ, Bond PJ, Klenerman D, Bryant CE.

Elife. 2018 Jan 24;7. pii: e31377. doi: 10.7554/eLife.31377.

9.

CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma.

Li Z, Ju X, Lee K, Clarke C, Hsu JL, Abadir E, Bryant CE, Pears S, Sunderland N, Heffernan S, Hennessy A, Lo TH, Pietersz GA, Kupresanin F, Fromm PD, Silveira PA, Tsonis C, Cooper WA, Cunningham I, Brown C, Clark GJ, Hart DNJ.

Haematologica. 2018 Apr;103(4):655-665. doi: 10.3324/haematol.2017.178384. Epub 2018 Jan 19.

10.

Influence of Type I Fimbriae and Fluid Shear Stress on Bacterial Behavior and Multicellular Architecture of Early Escherichia coli Biofilms at Single-Cell Resolution.

Wang L, Keatch R, Zhao Q, Wright JA, Bryant CE, Redmann AL, Terentjev EM.

Appl Environ Microbiol. 2018 Mar 1;84(6). pii: e02343-17. doi: 10.1128/AEM.02343-17. Print 2018 Mar 15.

11.

Visualising pattern recognition receptor signalling.

Macleod C, Bryant CE.

Biochem Soc Trans. 2017 Oct 15;45(5):1077-1085. doi: 10.1042/BST20160459. Epub 2017 Aug 24. Review.

PMID:
28842530
12.

Assessing the Collective Dynamics of Motile Cilia in Cultures of Human Airway Cells by Multiscale DDM.

Feriani L, Juenet M, Fowler CJ, Bruot N, Chioccioli M, Holland SM, Bryant CE, Cicuta P.

Biophys J. 2017 Jul 11;113(1):109-119. doi: 10.1016/j.bpj.2017.05.028.

13.

Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species.

Iljina M, Hong L, Horrocks MH, Ludtmann MH, Choi ML, Hughes CD, Ruggeri FS, Guilliams T, Buell AK, Lee JE, Gandhi S, Lee SF, Bryant CE, Vendruscolo M, Knowles TPJ, Dobson CM, De Genst E, Klenerman D.

BMC Biol. 2017 Jul 3;15(1):57. doi: 10.1186/s12915-017-0390-6.

14.

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88.

Sakai J, Cammarota E, Wright JA, Cicuta P, Gottschalk RA, Li N, Fraser IDC, Bryant CE.

Sci Rep. 2017 May 3;7(1):1428. doi: 10.1038/s41598-017-01600-y.

15.

Inflammasome Priming in Sterile Inflammatory Disease.

Patel MN, Carroll RG, Galván-Peña S, Mills EL, Olden R, Triantafilou M, Wolf AI, Bryant CE, Triantafilou K, Masters SL.

Trends Mol Med. 2017 Feb;23(2):165-180. doi: 10.1016/j.molmed.2016.12.007. Epub 2017 Jan 18. Review.

PMID:
28109721
16.

The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold.

Dossang AC, Motshwene PG, Yang Y, Symmons MF, Bryant CE, Borman S, George J, Weber AN, Gay NJ.

Sci Rep. 2016 Nov 23;6:37267. doi: 10.1038/srep37267.

17.

Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein.

Iljina M, Tosatto L, Choi ML, Sang JC, Ye Y, Hughes CD, Bryant CE, Gandhi S, Klenerman D.

Sci Rep. 2016 Sep 27;6:33928. doi: 10.1038/srep33928.

18.

CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages.

Pereira M, Tourlomousis P, Wright J, P Monie T, Bryant CE.

Nat Commun. 2016 Sep 27;7:12874. doi: 10.1038/ncomms12874.

19.

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.

Mills EL, Kelly B, Logan A, Costa ASH, Varma M, Bryant CE, Tourlomousis P, Däbritz JHM, Gottlieb E, Latorre I, Corr SC, McManus G, Ryan D, Jacobs HT, Szibor M, Xavier RJ, Braun T, Frezza C, Murphy MP, O'Neill LA.

Cell. 2016 Oct 6;167(2):457-470.e13. doi: 10.1016/j.cell.2016.08.064. Epub 2016 Sep 22.

20.

The killer protein Gasdermin D.

Wright JA, Bryant CE.

Cell Death Differ. 2016 Dec;23(12):1897-1898. doi: 10.1038/cdd.2016.100. Epub 2016 Sep 16. No abstract available.

21.

Exploring the dynamics of a free fruit at work intervention.

Lake AA, Smith SA, Bryant CE, Alinia S, Brandt K, Seal CJ, Tetens I.

BMC Public Health. 2016 Aug 19;16(1):839. doi: 10.1186/s12889-016-3500-4.

22.

CMRF-56(+) blood dendritic cells loaded with mRNA induce effective antigen-specific cytotoxic T-lymphocyte responses.

Fromm PD, Papadimitrious MS, Hsu JL, Van Kooten Losio N, Verma ND, Lo TH, Silveira PA, Bryant CE, Turtle CJ, Prue RL, Vukovic P, Munster DJ, Nagasaki T, Barnard RT, Mahler SM, Anguille SA, Berneman Z, Horvath LG, Bradstock KF, Joshua DE, Clark GJ, Hart DN.

Oncoimmunology. 2016 May 5;5(6):e1168555. doi: 10.1080/2162402X.2016.1168555. eCollection 2016 Jun.

23.

IL-27 Induced by Select Candida spp. via TLR7/NOD2 Signaling and IFN-β Production Inhibits Fungal Clearance.

Patin EC, Jones AV, Thompson A, Clement M, Liao CT, Griffiths JS, Wallace LE, Bryant CE, Lang R, Rosenstiel P, Humphreys IR, Taylor PR, Jones GW, Orr SJ.

J Immunol. 2016 Jul 1;197(1):208-21. doi: 10.4049/jimmunol.1501204. Epub 2016 Jun 3.

24.

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

Falcone EL, Abusleme L, Swamydas M, Lionakis MS, Ding L, Hsu AP, Zelazny AM, Moutsopoulos NM, Kuhns DB, Deming C, Quiñones M, Segre JA, Bryant CE, Holland SM.

Microbiome. 2016 Apr 5;4:13. doi: 10.1186/s40168-016-0159-0.

25.

Allergens and Activation of the Toll-Like Receptor Response.

Monie TP, Bryant CE.

Methods Mol Biol. 2016;1390:341-50. doi: 10.1007/978-1-4939-3335-8_21.

PMID:
26803639
26.

Energetics of Endotoxin Recognition in the Toll-Like Receptor 4 Innate Immune Response.

Paramo T, Tomasio SM, Irvine KL, Bryant CE, Bond PJ.

Sci Rep. 2015 Dec 9;5:17997. doi: 10.1038/srep17997.

27.

Critical residues involved in Toll-like receptor 4 activation by cationic lipid nanocarriers are not located at the lipopolysaccharide-binding interface.

Lonez C, Irvine KL, Pizzuto M, Schmidt BI, Gay NJ, Ruysschaert JM, Gangloff M, Bryant CE.

Cell Mol Life Sci. 2015 Oct;72(20):3971-82. doi: 10.1007/s00018-015-1915-1. Epub 2015 May 9.

28.

Caspase-8 functions as a key mediator of inflammation and pro-IL-1β processing via both canonical and non-canonical pathways.

Monie TP, Bryant CE.

Immunol Rev. 2015 May;265(1):181-93. doi: 10.1111/imr.12284. Review.

PMID:
25879293
29.

Advances in Toll-like receptor biology: Modes of activation by diverse stimuli.

Bryant CE, Gay NJ, Heymans S, Sacre S, Schaefer L, Midwood KS.

Crit Rev Biochem Mol Biol. 2015;50(5):359-79. doi: 10.3109/10409238.2015.1033511. Epub 2015 Apr 10. Review.

PMID:
25857820
30.

International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease.

Bryant CE, Orr S, Ferguson B, Symmons MF, Boyle JP, Monie TP.

Pharmacol Rev. 2015;67(2):462-504. doi: 10.1124/pr.114.009928. Review.

31.

The frequency and duration of Salmonella-macrophage adhesion events determines infection efficiency.

Achouri S, Wright JA, Evans L, Macleod C, Fraser G, Cicuta P, Bryant CE.

Philos Trans R Soc Lond B Biol Sci. 2015 Feb 5;370(1661):20140033. doi: 10.1098/rstb.2014.0033.

32.

Actin polymerization as a key innate immune effector mechanism to control Salmonella infection.

Man SM, Ekpenyong A, Tourlomousis P, Achouri S, Cammarota E, Hughes K, Rizzo A, Ng G, Wright JA, Cicuta P, Guck JR, Bryant CE.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17588-93. doi: 10.1073/pnas.1419925111. Epub 2014 Nov 24.

33.

The TLR4 D299G and T399I SNPs are constitutively active to up-regulate expression of Trif-dependent genes.

Hold GL, Berry S, Saunders KA, Drew J, Mayer C, Brookes H, Gay NJ, El-Omar EM, Bryant CE.

PLoS One. 2014 Nov 3;9(11):e111460. doi: 10.1371/journal.pone.0111460. eCollection 2014.

34.

Toll-like receptor signalling through macromolecular protein complexes.

Bryant CE, Symmons M, Gay NJ.

Mol Immunol. 2015 Feb;63(2):162-5. doi: 10.1016/j.molimm.2014.06.033. Epub 2014 Jul 28. Review.

PMID:
25081091
35.

The COP II adaptor protein TMED7 is required to initiate and mediate the delivery of TLR4 to the plasma membrane.

Liaunardy-Jopeace A, Bryant CE, Gay NJ.

Sci Signal. 2014 Jul 29;7(336):ra70. doi: 10.1126/scisignal.2005275.

36.

Assembly and localization of Toll-like receptor signalling complexes.

Gay NJ, Symmons MF, Gangloff M, Bryant CE.

Nat Rev Immunol. 2014 Aug;14(8):546-58. doi: 10.1038/nri3713. Review.

PMID:
25060580
37.

Identification of key residues that confer Rhodobacter sphaeroides LPS activity at horse TLR4/MD-2.

Irvine KL, Gangloff M, Walsh CM, Spring DR, Gay NJ, Bryant CE.

PLoS One. 2014 May 30;9(5):e98776. doi: 10.1371/journal.pone.0098776. eCollection 2014.

38.

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

Man SM, Hopkins LJ, Nugent E, Cox S, Glück IM, Tourlomousis P, Wright JA, Cicuta P, Monie TP, Bryant CE.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7403-8. doi: 10.1073/pnas.1402911111. Epub 2014 May 6.

39.

Non-nutritive sweeteners: no class effect on the glycaemic or appetite responses to ingested glucose.

Bryant CE, Wasse LK, Astbury N, Nandra G, McLaughlin JT.

Eur J Clin Nutr. 2014 May;68(5):629-31. doi: 10.1038/ejcn.2014.19. Epub 2014 Mar 5.

40.

The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system.

Moshayedi P, Ng G, Kwok JC, Yeo GS, Bryant CE, Fawcett JW, Franze K, Guck J.

Biomaterials. 2014 Apr;35(13):3919-25. doi: 10.1016/j.biomaterials.2014.01.038. Epub 2014 Feb 11.

41.

Impact of diet and weight loss on iron and zinc status in overweight and obese young women.

Cheng HL, Griffin HJ, Bryant CE, Rooney KB, Steinbeck KS, O'Connor HT.

Asia Pac J Clin Nutr. 2013;22(4):574-82. doi: 10.6133/apjcn.2013.22.4.08.

42.

The structural basis for endotoxin-induced allosteric regulation of the Toll-like receptor 4 (TLR4) innate immune receptor.

Paramo T, Piggot TJ, Bryant CE, Bond PJ.

J Biol Chem. 2013 Dec 20;288(51):36215-25. doi: 10.1074/jbc.M113.501957. Epub 2013 Oct 30.

43.

Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production.

Man SM, Tourlomousis P, Hopkins L, Monie TP, Fitzgerald KA, Bryant CE.

J Immunol. 2013 Nov 15;191(10):5239-46. doi: 10.4049/jimmunol.1301581. Epub 2013 Oct 11.

44.

Phagocytosis dynamics depends on target shape.

Paul D, Achouri S, Yoon YZ, Herre J, Bryant CE, Cicuta P.

Biophys J. 2013 Sep 3;105(5):1143-50. doi: 10.1016/j.bpj.2013.07.036.

45.

Clostridium difficile modulates host innate immunity via toxin-independent and dependent mechanism(s).

Jafari NV, Kuehne SA, Bryant CE, Elawad M, Wren BW, Minton NP, Allan E, Bajaj-Elliott M.

PLoS One. 2013 Jul 29;8(7):e69846. doi: 10.1371/journal.pone.0069846. Print 2013.

46.

Iron, hepcidin and inflammatory status of young healthy overweight and obese women in Australia.

Cheng HL, Bryant CE, Rooney KB, Steinbeck KS, Griffin HJ, Petocz P, O'Connor HT.

PLoS One. 2013 Jul 4;8(7):e68675. doi: 10.1371/journal.pone.0068675. Print 2013.

47.

The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6.

Irvine KL, Hopkins LJ, Gangloff M, Bryant CE.

Vet Res. 2013 Jul 4;44:50. doi: 10.1186/1297-9716-44-50.

48.

A quantitative comparison of single-dye tracking analysis tools using Monte Carlo simulations.

Weimann L, Ganzinger KA, McColl J, Irvine KL, Davis SJ, Gay NJ, Bryant CE, Klenerman D.

PLoS One. 2013 May 30;8(5):e64287. doi: 10.1371/journal.pone.0064287. Print 2013.

49.

Abnormal nasal nitric oxide production, ciliary beat frequency, and Toll-like receptor response in pulmonary nontuberculous mycobacterial disease epithelium.

Fowler CJ, Olivier KN, Leung JM, Smith CC, Huth AG, Root H, Kuhns DB, Logun C, Zelazny A, Frein CA, Daub J, Haney C, Shelhamer JH, Bryant CE, Holland SM.

Am J Respir Crit Care Med. 2013 Jun 15;187(12):1374-81. doi: 10.1164/rccm.201212-2197OC.

50.

Cell swelling and the NLRP3 inflammasome.

Boyle JP, Bryant CE, Monie TP.

Immunity. 2013 Mar 21;38(3):399. doi: 10.1016/j.immuni.2013.02.006. No abstract available.

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