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Items: 37

1.

Extracellular loop 3 of the noradrenaline transporter contributes to substrate and inhibitor selectivity.

Lynagh T, Khamu TS, Bryan-Lluka LJ.

Naunyn Schmiedebergs Arch Pharmacol. 2014 Jan;387(1):95-107. doi: 10.1007/s00210-013-0923-7. Epub 2013 Oct 1.

PMID:
24081522
2.

Investigation of the functional roles of the MELAL and GQXXRXG motifs of the human noradrenaline transporter using cysteine mutants.

Sucic S, Bryan-Lluka LJ.

Eur J Pharmacol. 2007 Feb 5;556(1-3):27-35. Epub 2006 Nov 3.

PMID:
17141753
3.

A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis.

Ruddell RG, Oakley F, Hussain Z, Yeung I, Bryan-Lluka LJ, Ramm GA, Mann DA.

Am J Pathol. 2006 Sep;169(3):861-76.

4.

Dose determination of haloperidol, risperidone and olanzapine using an in vivo dopamine D2-receptor occupancy method in the rat.

Naiker DV, Catts SV, Catts VS, Bedi KS, Bryan-Lluka LJ.

Eur J Pharmacol. 2006 Jul 1;540(1-3):87-90. Epub 2006 May 11.

PMID:
16730699
5.
6.
7.

Nitric oxide donors inhibit 5-hydroxytryptamine (5-HT) uptake by the human 5-HT transporter (SERT).

Bryan-Lluka LJ, Papacostas MH, Paczkowski FA, Wanstall JC.

Br J Pharmacol. 2004 Sep;143(1):63-70. Epub 2004 Aug 9.

8.
9.

chi-Conopeptide MrIA partially overlaps desipramine and cocaine binding sites on the human norepinephrine transporter.

Bryan-Lluka LJ, Bönisch H, Lewis RJ.

J Biol Chem. 2003 Oct 10;278(41):40324-9. Epub 2003 Jul 1.

10.

5-Hydroxytryptamine and platelets: uptake and aggregation in hypoxic pulmonary hypertensive rats.

Awabdy D, Bryan-Lluka LJ, Wanstall JC.

Eur J Pharmacol. 2003 Jan 10;459(1):1-7.

PMID:
12505528
11.

The role of the conserved GXXXRXG motif in the expression and function of the human norepinephrine transporter.

Sucic S, Bryan-Lluka LJ.

Brain Res Mol Brain Res. 2002 Dec;108(1-2):40-50.

PMID:
12480177
12.

Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter.

Sucic S, Paczkowski FA, Runkel F, Bönisch H, Bryan-Lluka LJ.

J Neurochem. 2002 Apr;81(2):344-54.

13.

Amino acids involved in differences in the pharmacological profiles of the rat and human noradrenaline transporters.

Paczkowski FA, Bryan-Lluka LJ.

Naunyn Schmiedebergs Arch Pharmacol. 2002 Apr;365(4):312-7. Epub 2002 Feb 20.

PMID:
11919656
14.

Pharmacological properties of the naturally occurring Ala(457)Pro variant of the human norepinephrine transporter.

Paczkowski FA, Bönisch H, Bryan-Lluka LJ.

Pharmacogenetics. 2002 Mar;12(2):165-73.

PMID:
11875370
15.

Tyrosine residue 271 of the norepinephrine transporter is an important determinant of its pharmacology.

Paczkowski FA, Bryan-Lluka LJ.

Brain Res Mol Brain Res. 2001 Dec 16;97(1):32-42.

PMID:
11744160
16.

Effects of short- and long-term exposure to c-AMP and c-GMP on the noradrenaline transporter.

Bryan-Lluka LJ, Paczkowski FA, Bönisch H.

Neuropharmacology. 2001 Mar;40(4):607-17.

PMID:
11249970
17.

Specific uptake of 5-hydroxytryptamine is reduced in lungs from hypoxic pulmonary hypertensive rats.

Jeffery TK, Bryan-Lluka LJ, Wanstall JC.

Eur J Pharmacol. 2000 May 19;396(2-3):137-40.

PMID:
10822067
18.
19.

Potencies of haloperidol metabolites as inhibitors of the human noradrenaline, dopamine and serotonin transporters in transfected COS-7 cells.

Bryan-Lluka LJ, Siebert GA, Pond SM.

Naunyn Schmiedebergs Arch Pharmacol. 1999 Aug;360(2):109-15.

PMID:
10494878
20.

Comparison of the pharmacological properties of cloned rat, human, and bovine norepinephrine transporters.

Paczkowski FA, Bryan-Lluka LJ, Pörzgen P, Brüss M, Bönisch H.

J Pharmacol Exp Ther. 1999 Aug;290(2):761-7.

PMID:
10411589
21.

The rat norepinephrine transporter: molecular cloning from PC12 cells and functional expression.

Brüss M, Pörzgen P, Bryan-Lluka LJ, Bönisch H.

Brain Res Mol Brain Res. 1997 Dec 15;52(2):257-62.

PMID:
9495547
22.

Catecholamine uptake and metabolism in rat lungs.

Bryan-Lluka LJ, James KM, Bönisch H, Pörzgen P, Guice KS, Oldham KT.

Adv Pharmacol. 1998;42:353-6. No abstract available.

PMID:
9327914
23.

Efflux studies allow further characterisation of the noradrenaline and 5-hydroxytryptamine transporters in rat lungs.

James KM, Bryan-Lluka LJ.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Jul;356(1):126-33.

PMID:
9228199
24.

Lanthanides inhibit the human noradrenaline, 5-hydroxytryptamine and dopamine transporters.

Bryan-Lluka LJ, Bönisch H.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Jun;355(6):699-706.

PMID:
9205953
25.

Amezinium and debrisoquine are substrates of uptake1 and potent inhibitors of monoamine oxidase in perfused lungs of rats.

Bryan-Lluka LJ, Seers H, Sharpe I.

Naunyn Schmiedebergs Arch Pharmacol. 1996 Apr;353(5):536-44.

PMID:
8740147
26.

Evidence for uptake1-mediated efflux of catecholamines from pulmonary endothelial cells of perfused lungs of rats.

Westwood NN, Scarcella DL, Bryan-Lluka LJ.

Naunyn Schmiedebergs Arch Pharmacol. 1996 Apr;353(5):528-35.

PMID:
8740146
27.

Conclusive evidence for distinct transporters for 5-hydroxytryptamine and noradrenaline in pulmonary endothelial cells of the rat.

Paczkowski NJ, Vuocolo HE, Bryan-Lluka LJ.

Naunyn Schmiedebergs Arch Pharmacol. 1996 Mar;353(4):423-30.

PMID:
8935709
28.

A kinetic investigation of the pulmonary metabolism of dopamine in rats shows marked differences compared with noradrenaline.

Scarcella DL, Bryan-Lluka LJ.

Naunyn Schmiedebergs Arch Pharmacol. 1995 May;351(5):491-9.

PMID:
7643912
29.
30.

Effects of albumin sensitization and challenge of guinea pigs on uptake2 of isoprenaline in trachealis muscle.

Bryan-Lluka LJ, Vuocolo HE.

Naunyn Schmiedebergs Arch Pharmacol. 1994 Jun;349(6):578-82.

PMID:
7969508
31.

Types A and B monoamine oxidase contribute to the metabolism of norepinephrine in perfused lungs of rats.

Westwood NN, Bryan-Lluka LJ.

J Pharmacol Exp Ther. 1993 Nov;267(2):815-21.

PMID:
8246156
32.

The effects of (-)-cromakalim and glibenclamide on uptake2 in guinea-pig trachealis muscle.

Bryan-Lluka LJ, Vuocolo HE.

Naunyn Schmiedebergs Arch Pharmacol. 1993 Jul;348(1):65-9.

PMID:
8377841
33.

Evidence from guinea-pig trachealis that Uptake2 of isoprenaline is enhanced by hyperpolarization of the smooth muscle.

Bryan-Lluka LJ, Vuocolo HE.

Naunyn Schmiedebergs Arch Pharmacol. 1992 Oct;346(4):399-404.

PMID:
1359431
34.

Dopamine and adrenaline, but not isoprenaline, are substrates for uptake and metabolism in isolated perfused lungs of rats.

Bryan-Lluka LJ, O'Donnell SR.

Naunyn Schmiedebergs Arch Pharmacol. 1992 Jul;346(1):20-6.

PMID:
1407001
35.

Vascular uptake of catecholamines in perfused lungs of the rat occurs by the same process as Uptake1 in noradrenergic neurones.

Bryan-Lluka LJ, Westwood NN, O'Donnell SR.

Naunyn Schmiedebergs Arch Pharmacol. 1992 Mar;345(3):319-26.

PMID:
1535692
37.

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