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Bosentan for patients with steroid-resistant pulmonary sarcoidosis: a randomised controlled trial.

Hostettler K, Baty F, Kleiner R, Junker L, Tamm M, Brutsche M.

Swiss Med Wkly. 2018 Oct 28;148:w14677. doi: 10.4414/smw.2018.14677. eCollection 2018 Oct 22.


Diagnosis, Prevention and Treatment of Stable COPD and Acute Exacerbations of COPD: The Swiss Recommendations 2018.

Stolz D, Barandun J, Borer H, Bridevaux PO, Brun P, Brutsche M, Clarenbach C, Eich C, Fiechter R, Frey M, Geiser T, Grob M, Helfenstein E, Junker L, Kohler M, Latshang T, Lechmann A, Maurer M, Nicod L, Quadri F, Schilter D, Sigrist T, Soccal P, Tarr P, Thurnheer R, Turk A, Tamm M.

Respiration. 2018;96(4):382-398. doi: 10.1159/000490551. Epub 2018 Aug 23.


Physical activity declines in COPD while exercise capacity remains stable: A longitudinal study over 5 years.

Sievi NA, Brack T, Brutsche MH, Frey M, Irani S, Leuppi JD, Thurnheer R, Kohler M, Clarenbach CF.

Respir Med. 2018 Aug;141:1-6. doi: 10.1016/j.rmed.2018.06.013. Epub 2018 Jun 18.


Quantifying patient centered outcomes associated with the use of bilateral endobronchial coil treatment in patients with severe emphysema.

Evans R, Brutsche M, Busca R, Deslee G, de Soyza A, Fellrath JM, Franzen D, Hartman J, Mealing S, Morton T, Munavvar M, Sculpher M, Shah P, Slebos DJ, Durand-Zaleski I.

Curr Med Res Opin. 2018 Nov;34(11):1927-1932. doi: 10.1080/03007995.2018.1462784. Epub 2018 May 8.


CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses.

Cheng HW, Onder L, Cupovic J, Boesch M, Novkovic M, Pikor N, Tarantino I, Rodriguez R, Schneider T, Jochum W, Brutsche M, Ludewig B.

J Allergy Clin Immunol. 2018 Oct;142(4):1257-1271.e4. doi: 10.1016/j.jaci.2017.12.998. Epub 2018 Jan 31.


Longitudinal change of COPD assessment test (CAT) in a telehealthcare cohort is associated with exacerbation risk.

Rassouli F, Baty F, Stolz D, Albrich WC, Tamm M, Widmer S, Brutsche MH.

Int J Chron Obstruct Pulmon Dis. 2017 Oct 24;12:3103-3109. doi: 10.2147/COPD.S141646. eCollection 2017.


Multimodel inference applied to oxygen recovery kinetics after 6-min walk tests in patients with chronic obstructive pulmonary disease.

Baty F, Ritz C, Jensen SM, Kern L, Tamm M, Brutsche MH.

PLoS One. 2017 Nov 8;12(11):e0187548. doi: 10.1371/journal.pone.0187548. eCollection 2017.


Accelerometer- versus questionnaire-based assessment of physical activity and their changes over time in patients with COPD.

Sievi NA, Brack T, Brutsche MH, Frey M, Irani S, Leuppi JD, Thurnheer R, Kohler M, Clarenbach CF.

Int J Chron Obstruct Pulmon Dis. 2017 Apr 10;12:1113-1118. doi: 10.2147/COPD.S130195. eCollection 2017.


Determinants of annual change in physical activity in COPD.

Clarenbach CF, Sievi NA, Haile SR, Brack T, Brutsche MH, Frey M, Irani S, Leuppi JD, Thurnheer R, Kohler M.

Respirology. 2017 Aug;22(6):1133-1139. doi: 10.1111/resp.13035. Epub 2017 Mar 30.


24h-gene variation effect of combined bevacizumab/erlotinib in advanced non-squamous non-small cell lung cancer using exon array blood profiling.

Baty F, Joerger M, Früh M, Klingbiel D, Zappa F, Brutsche M.

J Transl Med. 2017 Mar 30;15(1):66. doi: 10.1186/s12967-017-1174-z.


Idiopathic Pulmonary Fibrosis in Switzerland: Diagnosis and Treatment.

Funke-Chambour M, Azzola A, Adler D, Barazzone-Argiroffo C, Benden C, Boehler A, Bridevaux PO, Brutsche M, Clarenbach CF, Hostettler K, Kleiner-Finger R, Nicod LP, Soccal PM, Tamm M, Geiser T, Lazor R.

Respiration. 2017;93(5):363-378. doi: 10.1159/000464332. Epub 2017 Mar 25.


Sputum DNA sequencing in cystic fibrosis: non-invasive access to the lung microbiome and to pathogen details.

Feigelman R, Kahlert CR, Baty F, Rassouli F, Kleiner RL, Kohler P, Brutsche MH, von Mering C.

Microbiome. 2017 Feb 10;5(1):20. doi: 10.1186/s40168-017-0234-1.


Indacaterol and glycopyrronium versus indacaterol on body plethysmography measurements in COPD-a randomised controlled study.

Salomon J, Stolz D, Domenighetti G, Frey JG, Turk AJ, Azzola A, Sigrist T, Fitting JW, Schmidt U, Geiser T, Wild C, Kostikas K, Clemens A, Brutsche M.

Respir Res. 2017 Jan 11;18(1):13. doi: 10.1186/s12931-016-0498-1.


Transcutaneous versus blood carbon dioxide monitoring during acute noninvasive ventilation in the emergency department - a retrospective analysis.

Horvath CM, Brutsche MH, Baty F, Rüdiger JJ.

Swiss Med Wkly. 2016 Oct 26;146:w14373. doi: 10.4414/smw.2016.14373. eCollection 2016.


Oxygen Uptake Recovery Kinetics after the 6-Minute Walk Test in Patients with Chronic Obstructive Pulmonary Disease.

Baty F, van Gestel AJ, Kern L, Brutsche MH.

Respiration. 2016;92(6):371-379. Epub 2016 Nov 9.


Erratum to: NIV by an interdisciplinary respiratory care team in severe respiratory failure in the emergency department limited to day time hours.

Horvath CM, Brutsche MH, Schoch OD, Schillig B, Baty F, vonOw D, Rüdiger JJ.

Intern Emerg Med. 2017 Dec;12(8):1339. doi: 10.1007/s11739-016-1569-5. No abstract available.


NIV by an interdisciplinary respiratory care team in severe respiratory failure in the emergency department limited to day time hours.

Horvath CM, Brutsche MH, Schoch OD, Schillig B, Baty F, vonOw D, Rüdiger JJ.

Intern Emerg Med. 2017 Dec;12(8):1215-1223. doi: 10.1007/s11739-016-1546-z. Epub 2016 Oct 8. Erratum in: Intern Emerg Med. 2017 Dec;12 (8):1339. Brutsche, Martin Horvath [corrected to Brutsche, Martin Hugo].


Erlotinib has comparable clinical efficacy to chemotherapy in pretreated patients with advanced non-small cell lung cancer (NSCLC): A propensity-adjusted, outcomes research-based study.

Neumair P, Joos L, Warschkow R, Dutly A, Ess S, Hitz F, Früh M, Brutsche M, Baty F, Krähenbühl S, Cerny T, Joerger M.

Lung Cancer. 2016 Oct;100:38-44. doi: 10.1016/j.lungcan.2016.07.027. Epub 2016 Jul 28.


Telehealthcare for Chronic Obstructive Pulmonary Disease in Switzerland Is Feasible and Appreciated by Patients.

Rassouli F, Pfister M, Widmer S, Baty F, Burger B, Brutsche MH.

Respiration. 2016;92(2):107-13. doi: 10.1159/000448377. Epub 2016 Aug 24.


Modeling the oxygen uptake kinetics during exercise testing of patients with chronic obstructive pulmonary diseases using nonlinear mixed models.

Baty F, Ritz C, van Gestel A, Brutsche M, Gerhard D.

BMC Med Res Methodol. 2016 Jun 1;16:66. doi: 10.1186/s12874-016-0173-8.


Comparison of next generation sequencing, SNaPshot assay and real-time polymerase chain reaction for lung adenocarcinoma EGFR mutation assessment.

Cernomaz AT, Macovei II, Pavel I, Grigoriu C, Marinca M, Baty F, Peter S, Zonda R, Brutsche M, Grigoriu B.

BMC Pulm Med. 2016 May 23;16(1):88. doi: 10.1186/s12890-016-0250-0.


Handheld single photon emission computed tomography (handheld SPECT) navigated video-assisted thoracoscopic surgery of computer tomography-guided radioactively marked pulmonary lesions.

Müller J, Putora PM, Schneider T, Zeisel C, Brutsche M, Baty F, Markus A, Kick J.

Interact Cardiovasc Thorac Surg. 2016 Sep;23(3):345-50. doi: 10.1093/icvts/ivw136. Epub 2016 May 20.


In-Hospital Disease Burden of Sarcoidosis in Switzerland from 2002 to 2012.

Pohle S, Baty F, Brutsche M.

PLoS One. 2016 Mar 17;11(3):e0151940. doi: 10.1371/journal.pone.0151940. eCollection 2016.


[Sarcoidosis--a multisystem disorder with variable prognosis].

Kleiner R, Brutsche M.

Ther Umsch. 2016;73(1):31-5. doi: 10.1024/0040-5930/a000752. Review. German.


High-throughput alternative splicing detection using dually constrained correspondence analysis (DCCA).

Baty F, Klingbiel D, Zappa F, Brutsche M.

J Biomed Inform. 2015 Dec;58:175-185. doi: 10.1016/j.jbi.2015.10.002. Epub 2015 Oct 19.


Effect of telemetric monitoring in the first 30 days of continuous positive airway pressure adaptation for obstructive sleep apnoea syndrome - a controlled pilot study.

Frasnelli M, Baty F, Niedermann J, Brutsche MH, Schoch OD.

J Telemed Telecare. 2016 Jun;22(4):209-14. doi: 10.1177/1357633X15598053. Epub 2015 Aug 6.


Small RNA profiling reveals deregulated phosphatase and tensin homolog (PTEN)/phosphoinositide 3-kinase (PI3K)/Akt pathway in bronchial smooth muscle cells from asthmatic patients.

Alexandrova E, Miglino N, Hashim A, Nassa G, Stellato C, Tamm M, Baty F, Brutsche M, Weisz A, Borger P.

J Allergy Clin Immunol. 2016 Jan;137(1):58-67. doi: 10.1016/j.jaci.2015.05.031. Epub 2015 Jul 3.


[Cardiopulmonary exercise testing (CPET) – indication and clinical impact].

Hansen J, Rassouli F, Brutsche MH.

Ther Umsch. 2015 May;72(5):321-6. doi: 10.1024/0040-5930/a000682. Review. German.


Gene Expression Signatures Predictive of Bevacizumab/Erlotinib Therapeutic Benefit in Advanced Nonsquamous Non-Small Cell Lung Cancer Patients (SAKK 19/05 trial).

Franzini A, Baty F, Macovei II, Dürr O, Droege C, Betticher D, Grigoriu BD, Klingbiel D, Zappa F, Brutsche MH.

Clin Cancer Res. 2015 Dec 1;21(23):5253-63. doi: 10.1158/1078-0432.CCR-14-3135. Epub 2015 Apr 28.


[The role of chronic or transient hypoxia on the retinal nerve fiber layers].

Spahr Y, Brutsche M, Valmaggia C.

Klin Monbl Augenheilkd. 2015 Apr;232(4):395-8. doi: 10.1055/s-0035-1545751. Epub 2015 Apr 22. German.


Bevacizumab, Pemetrexed, and Cisplatin, or Bevacizumab and Erlotinib for Patients With Advanced Non-Small-Cell Lung Cancer Stratified by Epidermal Growth Factor Receptor Mutation: Phase II Trial SAKK19/09.

Gautschi O, Mach N, Rothschild SI, Li Q, Stahel RA, Zippelius A, Cathomas R, Früh M, Betticher DC, Peters S, Rauch D, Feilchenfeldt J, Bubendorf L, Savic S, Jaggi R, Leibundgut EO, Largiadèr C, Brutsche M, Pilop C, Stalder L, Pless M, Ochsenbein AF; Swiss Group for Clinical Cancer Research.

Clin Lung Cancer. 2015 Sep;16(5):358-65. doi: 10.1016/j.cllc.2015.02.007. Epub 2015 Mar 5.


[ARDS after Incidental Aspiration of Petroleum in an Adult].

Horvath CM, Schneider T, Kluckert T, Brutsche MH.

Pneumologie. 2015 Jun;69(6):341-4. doi: 10.1055/s-0034-1391377. Epub 2015 Jan 28. German.


Impact of comorbidities on physical activity in COPD.

Sievi NA, Senn O, Brack T, Brutsche MH, Frey M, Irani S, Leuppi JD, Thurnheer R, Franzen D, Kohler M, Clarenbach CF.

Respirology. 2015 Apr;20(3):413-8. doi: 10.1111/resp.12456. Epub 2015 Jan 6.


Accuracy of the Hospital Anxiety and Depression Scale for identifying depression in chronic obstructive pulmonary disease patients.

Nowak C, Sievi NA, Clarenbach CF, Schwarz EI, Schlatzer C, Brack T, Brutsche M, Frey M, Irani S, Leuppi JD, Rüdiger J, Thurnheer R, Kohler M.

Pulm Med. 2014;2014:973858. doi: 10.1155/2014/973858. Epub 2014 Dec 4.


Physical activity and the frequency of acute exacerbations in patients with chronic obstructive pulmonary disease.

Schönmann M, Sievi NA, Clarenbach CF, Brack T, Brutsche M, Frey M, Irani S, Leuppi JD, Ruediger J, Senn O, Thurnheer R, Kohler M.

Lung. 2015 Feb;193(1):63-70. doi: 10.1007/s00408-014-9673-7. Epub 2014 Dec 13.


Oxygen kinetics during 6-minute walk tests in patients with cardiovascular and pulmonary disease.

Kern L, Condrau S, Baty F, Wiegand J, van Gestel AJ, Azzola A, Tamm M, Brutsche M.

BMC Pulm Med. 2014 Oct 29;14:167. doi: 10.1186/1471-2466-14-167.


Cardiopulmonary and gas-exchange responses during the six-minute walk test in patients with chronic obstructive pulmonary disease.

van Gestel AJ, Baty F, Rausch-Osthof AK, Brutsche MH.

Respiration. 2014;88(4):307-14. doi: 10.1159/000365997. Epub 2014 Sep 9.


Comprehensive biomarker profiling in patients with obstructive sleep apnea.

Maeder MT, Strobel W, Christ M, Todd J, Estis J, Wildi K, Thalmann G, Hilti J, Brutsche M, Twerenbold R, Rickli H, Mueller C.

Clin Biochem. 2015 Mar;48(4-5):340-6. doi: 10.1016/j.clinbiochem.2014.09.005. Epub 2014 Sep 16.


The outcome of community-acquired pneumonia in patients with chronic lung disease: a case-control study.

Dusemund F, Chronis J, Baty F, Albrich WC, Brutsche MH.

Swiss Med Wkly. 2014 Sep 3;144:w14013. doi: 10.4414/smw.2014.14013. eCollection 2014.


Circulating microRNA profiling in patients with advanced non-squamous NSCLC receiving bevacizumab/erlotinib followed by platinum-based chemotherapy at progression (SAKK 19/05).

Joerger M, Baty F, Früh M, Droege C, Stahel RA, Betticher DC, von Moos R, Ochsenbein A, Pless M, Gautschi O, Rothschild S, Brauchli P, Klingbiel D, Zappa F, Brutsche M.

Lung Cancer. 2014 Aug;85(2):306-13. doi: 10.1016/j.lungcan.2014.04.014. Epub 2014 May 29.


Significant reduction of AECOPD hospitalisations after implementation of a public smoking ban in Graubünden, Switzerland.

Dusemund F, Baty F, Brutsche MH.

Tob Control. 2015 Jul;24(4):404-7. doi: 10.1136/tobaccocontrol-2013-051290. Epub 2014 Feb 5.


Midregional pro-adrenomedullin and copeptin: exercise kinetics and association with the cardiopulmonary exercise response in comparison to B-type natriuretic peptide.

Zurek M, Maeder MT, Brutsche MH, Lüthi A, Twerenbold R, Freese M, Rickli H, Mueller C.

Eur J Appl Physiol. 2014 Apr;114(4):815-24. doi: 10.1007/s00421-013-2815-4. Epub 2014 Jan 5.


Baseline predictors of adherence to positive airway pressure therapy for sleep apnea: a 10-year single-center observational cohort study.

Schoch OD, Baty F, Niedermann J, Rüdiger JJ, Brutsche MH.

Respiration. 2014;87(2):121-8. doi: 10.1159/000354186. Epub 2013 Nov 5.


Endobronchial ultrasound-guided transbronchial needle aspiration of an intravascular sarcoma metastasis.

Dusemund F, Schneider T, Zeisel C, Rothermundt C, Kluckert T, Schmid S, Brutsche MH.

Respiration. 2013;86(5):430-2. doi: 10.1159/000354183. Epub 2013 Sep 24.


EGFR exon-level biomarkers of the response to bevacizumab/erlotinib in non-small cell lung cancer.

Baty F, Rothschild S, Früh M, Betticher D, Dröge C, Cathomas R, Rauch D, Gautschi O, Bubendorf L, Crowe S, Zappa F, Pless M, Brutsche M; Swiss Group for Clinical Cancer Research.

PLoS One. 2013 Sep 10;8(9):e72966. doi: 10.1371/journal.pone.0072966. eCollection 2013.


Characteristics of medically and surgically treated empyema patients: a retrospective cohort study.

Dusemund F, Weber MD, Nagel W, Schneider T, Brutsche MH, Schoch OD.

Respiration. 2013;86(4):288-94. doi: 10.1159/000353424. Epub 2013 Aug 27.


Exploring the transcription factor activity in high-throughput gene expression data using RLQ analysis.

Baty F, Rüdiger J, Miglino N, Kern L, Borger P, Brutsche M.

BMC Bioinformatics. 2013 Jun 6;14:178. doi: 10.1186/1471-2105-14-178.


Epidermal growth factor receptor mutation in a patient with squamous cell carcinoma of the lung: who should be tested?

Schwitter M, Rodriguez R, Schneider T, Kluckert T, Brutsche M, Früh M.

Case Rep Oncol. 2013 May 14;6(2):263-8. doi: 10.1159/000351607. Print 2013 May.


Comorbidities and burden of COPD: a population based case-control study.

Baty F, Putora PM, Isenring B, Blum T, Brutsche M.

PLoS One. 2013 May 17;8(5):e63285. doi: 10.1371/journal.pone.0063285. Print 2013.


Analysis of the EGFR mutation status in head and neck squamous cell carcinoma before treatment with Gefitinib.

Bontognali S, Pless M, Brutsche MH, Fischer C, Rochlitz C, Buess M.

Onkologie. 2013;36(4):161-6. doi: 10.1159/000349941. Epub 2013 Mar 18.


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