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Items: 1 to 50 of 194

1.

Prevalence of Asthma and COPD and Blood Eosinophil Count in a Middle-Aged Belgian Population.

Wijnant SRA, Lahousse L, De Buyzere ML, Brusselle GG, Rietzschel ER.

J Clin Med. 2019 Jul 28;8(8). pii: E1122. doi: 10.3390/jcm8081122.

2.

Prevalence and burden of asthma in China: time to act.

Brusselle GG, Ko FW.

Lancet. 2019 Aug 3;394(10196):364-366. doi: 10.1016/S0140-6736(19)31349-2. Epub 2019 Jun 20. No abstract available.

PMID:
31230827
3.

Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression.

van der Plaat DA, Vonk JM, Terzikhan N, de Jong K, de Vries M, La Bastide-van Gemert S, van Diemen CC, Lahousse L, Brusselle GG, Nedeljkovic I, Amin N; BIOS Consortium, Kromhout H, Vermeulen RCH, Postma DS, van Duijn CM, Boezen HM.

Hum Mol Genet. 2019 Apr 2. pii: ddz067. doi: 10.1093/hmg/ddz067. [Epub ahead of print]

4.

Azithromycin during Acute COPD Exacerbations Requiring Hospitalization (BACE): a Multicentre, Randomized, Double-blind, Placebo-controlled Trial.

Vermeersch K, Gabrovska M, Aumann J, Demedts IK, Corhay JL, Marchand E, Slabbynck H, Haenebalcke C, Haerens M, Hanon S, Jordens P, Peché R, Fremault A, Lauwerier T, Delporte A, Vandenberk B, Willems R, Everaerts S, Belmans A, Bogaerts K, Verleden GM, Troosters T, Ninane V, Brusselle GG, Janssens W; BACE trial investigators.

Am J Respir Crit Care Med. 2019 May 3. doi: 10.1164/rccm.201901-0094OC. [Epub ahead of print]

PMID:
31046405
5.

The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD: current evidence and future prospects.

Derom E, Brusselle GG, Joos GF.

Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619843426. doi: 10.1177/1753466619843426.

6.

Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population.

van der Plaat DA, Vonk JM, Lahousse L, de Jong K, Faiz A, Nedeljkovic I, Amin N, van Diemen CC, Brusselle GG, Bossé Y, Brandsma CA, Hao K, Paré PD, van Duijn CM, Postma DS, Boezen HM.

BMC Pulm Med. 2019 Mar 7;19(1):58. doi: 10.1186/s12890-019-0811-0.

7.

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.

Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao D, Bartz TM, Kim DK, Lee MK, Latourelle JC, Li X, Morrow JD, Obeidat M, Wyss AB, Bakke P, Barr RG, Beaty TH, Belinsky SA, Brusselle GG, Crapo JD, de Jong K, DeMeo DL, Fingerlin TE, Gharib SA, Gulsvik A, Hall IP, Hokanson JE, Kim WJ, Lomas DA, London SJ, Meyers DA, O'Connor GT, Rennard SI, Schwartz DA, Sliwinski P, Sparrow D, Strachan DP, Tal-Singer R, Tesfaigzi Y, Vestbo J, Vonk JM, Yim JJ, Zhou X, Bossé Y, Manichaikul A, Lahousse L, Silverman EK, Boezen HM, Wain LV, Tobin MD, Hobbs BD, Cho MH; SpiroMeta Consortium; International COPD Genetics Consortium.

Nat Genet. 2019 Mar;51(3):494-505. doi: 10.1038/s41588-018-0342-2. Epub 2019 Feb 25.

PMID:
30804561
8.

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course.

den Dekker HT, Burrows K, Felix JF, Salas LA, Nedeljkovic I, Yao J, Rifas-Shiman SL, Ruiz-Arenas C, Amin N, Bustamante M, DeMeo DL, Henderson AJ, Howe CG, Hivert MF, Ikram MA, de Jongste JC, Lahousse L, Mandaviya PR, van Meurs JB, Pinart M, Sharp GC, Stolk L, Uitterlinden AG, Anto JM, Litonjua AA, Breton CV, Brusselle GG, Sunyer J, Smith GD, Relton CL, Jaddoe VWV, Duijts L.

Eur Respir J. 2019 Apr 4;53(4). pii: 1801795. doi: 10.1183/13993003.01795-2018. Print 2019 Apr.

PMID:
30765504
9.

Lifetime risk and multimorbidity of non-communicable diseases and disease-free life expectancy in the general population: A population-based cohort study.

Licher S, Heshmatollah A, van der Willik KD, Stricker BHC, Ruiter R, de Roos EW, Lahousse L, Koudstaal PJ, Hofman A, Fani L, Brusselle GGO, Bos D, Arshi B, Kavousi M, Leening MJG, Ikram MK, Ikram MA.

PLoS Med. 2019 Feb 4;16(2):e1002741. doi: 10.1371/journal.pmed.1002741. eCollection 2019 Feb.

10.

GDF-15 in Pulmonary and Critical Care Medicine.

Verhamme FM, Freeman CM, Brusselle GG, Bracke KR, Curtis JL.

Am J Respir Cell Mol Biol. 2019 Jun;60(6):621-628. doi: 10.1165/rcmb.2018-0379TR.

PMID:
30633545
11.

COPD is associated with an increased risk of peripheral artery disease and mortality.

Terzikhan N, Lahousse L, Verhamme KMC, Franco OH, Ikram AM, Stricker BH, Brusselle GG.

ERJ Open Res. 2018 Dec 21;4(4). pii: 00086-2018. doi: 10.1183/23120541.00086-2018. eCollection 2018 Oct.

12.

Bone morphogenetic protein 6 (BMP-6) modulates lung function, pulmonary iron levels and cigarette smoke-induced inflammation.

Verhamme FM, De Smet EG, Van Hooste W, Delanghe J, Verleden SE, Joos GF, Brusselle GG, Bracke KR.

Mucosal Immunol. 2019 Mar;12(2):340-351. doi: 10.1038/s41385-018-0116-2. Epub 2018 Dec 12.

PMID:
30542109
13.

Tralokinumab did not demonstrate oral corticosteroid-sparing effects in severe asthma.

Busse WW, Brusselle GG, Korn S, Kuna P, Magnan A, Cohen D, Bowen K, Piechowiak T, Wang MM, Colice G.

Eur Respir J. 2019 Jan 31;53(2). pii: 1800948. doi: 10.1183/13993003.00948-2018. Print 2019 Feb.

PMID:
30442714
14.

Chronic obstructive pulmonary disease and the development of atrial fibrillation.

Grymonprez M, Vakaet V, Kavousi M, Stricker BH, Ikram MA, Heeringa J, Franco OH, Brusselle GG, Lahousse L.

Int J Cardiol. 2019 Feb 1;276:118-124. doi: 10.1016/j.ijcard.2018.09.056. Epub 2018 Sep 15.

15.

Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function.

Xu J, Bartz TM, Chittoor G, Eiriksdottir G, Manichaikul AW, Sun F, Terzikhan N, Zhou X, Booth SL, Brusselle GG, de Boer IH, Fornage M, Frazier-Wood AC, Graff M, Gudnason V, Harris TB, Hofman A, Hou R, Houston DK, Jacobs DR, Kritchevsky SB, Latourelle J, Lemaitre RN, Lutsey PL, O'Connor G, Oelsner EC, Pankow JS, Psaty BM, Rohde RR, Rich SS, Rotter JI, Smith LJ, Stricker BH, Voruganti VS, Wang TJ, Zillikens MC, Barr RG, Dupuis J, Gharib SA, Lahousse L, London SJ, North KE, Smith AV, Steffen LM, Hancock DB, Cassano PA.

Br J Nutr. 2018 Nov;120(10):1159-1170. doi: 10.1017/S0007114518002180. Epub 2018 Sep 12.

16.

Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association.

Xu J, Gaddis NC, Bartz TM, Hou R, Manichaikul AW, Pankratz N, Smith AV, Sun F, Terzikhan N, Markunas CA, Patchen BK, Schu M, Beydoun MA, Brusselle GG, Eiriksdottir G, Zhou X, Wood AC, Graff M, Harris TB, Ikram MA, Jacobs DR Jr, Launer LJ, Lemaitre RN, O'Connor GT, Oelsner EC, Psaty BM, Vasan RS, Rohde RR, Rich SS, Rotter JI, Seshadri S, Smith LJ, Tiemeier H, Tsai MY, Uitterlinden AG, Voruganti VS, Xu H, Zilhão NR, Fornage M, Zillikens MC, London SJ, Barr RG, Dupuis J, Gharib SA, Gudnason V, Lahousse L, North KE, Steffen LM, Cassano PA, Hancock DB.

Am J Respir Crit Care Med. 2019 Mar 1;199(5):631-642. doi: 10.1164/rccm.201802-0304OC.

PMID:
30199657
17.

Meta-analysis of exome array data identifies six novel genetic loci for lung function.

Jackson VE, Latourelle JC, Wain LV, Smith AV, Grove ML, Bartz TM, Obeidat M, Province MA, Gao W, Qaiser B, Porteous DJ, Cassano PA, Ahluwalia TS, Grarup N, Li J, Altmaier E, Marten J, Harris SE, Manichaikul A, Pottinger TD, Li-Gao R, Lind-Thomsen A, Mahajan A, Lahousse L, Imboden M, Teumer A, Prins B, Lyytikäinen LP, Eiriksdottir G, Franceschini N, Sitlani CM, Brody JA, Bossé Y, Timens W, Kraja A, Loukola A, Tang W, Liu Y, Bork-Jensen J, Justesen JM, Linneberg A, Lange LA, Rawal R, Karrasch S, Huffman JE, Smith BH, Davies G, Burkart KM, Mychaleckyj JC, Bonten TN, Enroth S, Lind L, Brusselle GG, Kumar A, Stubbe B; Understanding Society Scientific Group, Kähönen M, Wyss AB, Psaty BM, Heckbert SR, Hao K, Rantanen T, Kritchevsky SB, Lohman K, Skaaby T, Pisinger C, Hansen T, Schulz H, Polasek O, Campbell A, Starr JM, Rich SS, Mook-Kanamori DO, Johansson Å, Ingelsson E, Uitterlinden AG, Weiss S, Raitakari OT, Gudnason V, North KE, Gharib SA, Sin DD, Taylor KD, O'Connor GT, Kaprio J, Harris TB, Pederson O, Vestergaard H, Wilson JG, Strauch K, Hayward C, Kerr S, Deary IJ, Barr RG, de Mutsert R, Gyllensten U, Morris AP, Ikram MA, Probst-Hensch N, Gläser S, Zeggini E, Lehtimäki T, Strachan DP, Dupuis J, Morrison AC, Hall IP, Tobin MD, London SJ.

Wellcome Open Res. 2018 Jan 12;3:4. doi: 10.12688/wellcomeopenres.12583.3. eCollection 2018.

18.

IL-33 signalling contributes to pollutant-induced allergic airway inflammation.

De Grove KC, Provoost S, Braun H, Blomme EE, Teufelberger AR, Krysko O, Beyaert R, Brusselle GG, Joos GF, Maes T.

Clin Exp Allergy. 2018 Dec;48(12):1665-1675. doi: 10.1111/cea.13261. Epub 2018 Sep 19.

PMID:
30159930
19.

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Wyss AB, Sofer T, Lee MK, Terzikhan N, Nguyen JN, Lahousse L, Latourelle JC, Smith AV, Bartz TM, Feitosa MF, Gao W, Ahluwalia TS, Tang W, Oldmeadow C, Duan Q, de Jong K, Wojczynski MK, Wang XQ, Noordam R, Hartwig FP, Jackson VE, Wang T, Obeidat M, Hobbs BD, Huan T, Gui H, Parker MM, Hu D, Mogil LS, Kichaev G, Jin J, Graff M, Harris TB, Kalhan R, Heckbert SR, Paternoster L, Burkart KM, Liu Y, Holliday EG, Wilson JG, Vonk JM, Sanders JL, Barr RG, de Mutsert R, Menezes AMB, Adams HHH, van den Berge M, Joehanes R, Levin AM, Liberto J, Launer LJ, Morrison AC, Sitlani CM, Celedón JC, Kritchevsky SB, Scott RJ, Christensen K, Rotter JI, Bonten TN, Wehrmeister FC, Bossé Y, Xiao S, Oh S, Franceschini N, Brody JA, Kaplan RC, Lohman K, McEvoy M, Province MA, Rosendaal FR, Taylor KD, Nickle DC, Williams LK, Burchard EG, Wheeler HE, Sin DD, Gudnason V, North KE, Fornage M, Psaty BM, Myers RH, O'Connor G, Hansen T, Laurie CC, Cassano PA, Sung J, Kim WJ, Attia JR, Lange L, Boezen HM, Thyagarajan B, Rich SS, Mook-Kanamori DO, Horta BL, Uitterlinden AG, Im HK, Cho MH, Brusselle GG, Gharib SA, Dupuis J, Manichaikul A, London SJ.

Nat Commun. 2018 Jul 30;9(1):2976. doi: 10.1038/s41467-018-05369-0.

20.

Heritability and genome-wide association study of diffusing capacity of the lung.

Terzikhan N, Sun F, Verhamme FM, Adams HHH, Loth D, Bracke KR, Stricker BHC, Lahousse L, Dupuis J, Brusselle GG, O'Connor GT.

Eur Respir J. 2018 Sep 15;52(3). pii: 1800647. doi: 10.1183/13993003.00647-2018. Print 2018 Sep.

PMID:
30049742
21.

Association between blood eosinophil count and risk of readmission for patients with asthma: Historical cohort study.

Kerkhof M, Tran TN, van den Berge M, Brusselle GG, Gopalan G, Jones RCM, Kocks JWH, Menzies-Gow A, Nuevo J, Pavord ID, Rastogi S, Price DB.

PLoS One. 2018 Jul 25;13(7):e0201143. doi: 10.1371/journal.pone.0201143. eCollection 2018.

22.

Influence of genetic variants on childhood lung function - The Generation R Study.

Shagiwal SS, den Dekker HT, de Jongste JC, Brusselle GG, Jaddoe VWV, Felix JF, Duijts L.

Pediatr Allergy Immunol. 2018 Sep;29(6):589-595. doi: 10.1111/pai.12931. Epub 2018 Jul 10.

PMID:
29882296
23.

Asthma and its comorbidities in middle-aged and older adults; the Rotterdam Study.

de Roos EW, Lahousse L, Verhamme KMC, Braunstahl GJ, Ikram MA, In 't Veen JCCM, Stricker BHC, Brusselle GGO.

Respir Med. 2018 Jun;139:6-12. doi: 10.1016/j.rmed.2018.04.006. Epub 2018 Apr 11.

PMID:
29858003
24.

Insights in particulate matter-induced allergic airway inflammation: Focus on the epithelium.

De Grove KC, Provoost S, Brusselle GG, Joos GF, Maes T.

Clin Exp Allergy. 2018 Jul;48(7):773-786. doi: 10.1111/cea.13178. Epub 2018 Jun 10. Review.

PMID:
29772098
25.

A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants.

Nedeljkovic I, Terzikhan N, Vonk JM, van der Plaat DA, Lahousse L, van Diemen CC, Hobbs BD, Qiao D, Cho MH, Brusselle GG, Postma DS, Boezen HM, van Duijn CM, Amin N.

Front Genet. 2018 Apr 19;9:133. doi: 10.3389/fgene.2018.00133. eCollection 2018.

26.

Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics.

Nedeljkovic I, Carnero-Montoro E, Lahousse L, van der Plaat DA, de Jong K, Vonk JM, van Diemen CC, Faiz A, van den Berge M, Obeidat M, Bossé Y, Nickle DC, Consortium B, Uitterlinden AG, van Meurs JJB, Stricker BCH, Brusselle GG, Postma DS, Boezen HM, van Duijn CM, Amin N.

Eur J Hum Genet. 2018 May;26(5):709-722. doi: 10.1038/s41431-017-0089-8. Epub 2018 Feb 8.

27.

Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD.

De Smet EG, Seys LJ, Verhamme FM, Vanaudenaerde BM, Brusselle GG, Bingle CD, Bracke KR.

Int J Chron Obstruct Pulmon Dis. 2017 Dec 19;13:11-27. doi: 10.2147/COPD.S144136. eCollection 2018.

28.

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, Bouzigon E, Brightling CE, Brossard M, Brusselle GG, Burchard E, Burkart KM, Bush A, Chan-Yeung M, Chung KF, Couto Alves A, Curtin JA, Custovic A, Daley D, de Jongste JC, Del-Rio-Navarro BE, Donohue KM, Duijts L, Eng C, Eriksson JG, Farrall M, Fedorova Y, Feenstra B, Ferreira MA; Australian Asthma Genetics Consortium (AAGC) collaborators, Freidin MB, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib SA, Gilliland F, Granell R, Graves PE, Gudbjartsson DF, Haahtela T, Heckbert SR, Heederik D, Heinrich J, Heliövaara M, Henderson J, Himes BE, Hirose H, Hirschhorn JN, Hofman A, Holt P, Hottenga J, Hudson TJ, Hui J, Imboden M, Ivanov V, Jaddoe VWV, James A, Janson C, Jarvelin MR, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kähönen M, Kantor DB, Karunas AS, Khusnutdinova E, Koppelman GH, Kozyrskyj AL, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee YA, Lehtimäki T, Letort S, Levin AM, Li G, Liang L, Loehr LR, London SJ, Loth DW, Manichaikul A, Marenholz I, Martinez FJ, Matheson MC, Mathias RA, Matsumoto K, Mbarek H, McArdle WL, Melbye M, Melén E, Meyers D, Michel S, Mohamdi H, Musk AW, Myers RA, Nieuwenhuis MAE, Noguchi E, O'Connor GT, Ogorodova LM, Palmer CD, Palotie A, Park JE, Pennell CE, Pershagen G, Polonikov A, Postma DS, Probst-Hensch N, Puzyrev VP, Raby BA, Raitakari OT, Ramasamy A, Rich SS, Robertson CF, Romieu I, Salam MT, Salomaa V, Schlünssen V, Scott R, Selivanova PA, Sigsgaard T, Simpson A, Siroux V, Smith LJ, Solodilova M, Standl M, Stefansson K, Strachan DP, Stricker BH, Takahashi A, Thompson PJ, Thorleifsson G, Thorsteinsdottir U, Tiesler CMT, Torgerson DG, Tsunoda T, Uitterlinden AG, van der Valk RJP, Vaysse A, Vedantam S, von Berg A, von Mutius E, Vonk JM, Waage J, Wareham NJ, Weiss ST, White WB, Wickman M, Widén E, Willemsen G, Williams LK, Wouters IM, Yang JJ, Zhao JH, Moffatt MF, Ober C, Nicolae DL.

Nat Genet. 2018 Jan;50(1):42-53. doi: 10.1038/s41588-017-0014-7. Epub 2017 Dec 22.

29.

Measures of subclinical cardiac dysfunction and increased filling pressures associate with pulmonary arterial pressure in the general population: results from the population-based Rotterdam Study.

Billar RJ, Leening MJG, Merkus D, Brusselle GGO, Hofman A, Stricker BHC, Ghofrani HA, Franco OH, Gall H, Felix JF.

Eur J Epidemiol. 2018 Apr;33(4):403-413. doi: 10.1007/s10654-017-0341-0. Epub 2017 Dec 13.

30.

Pulmonary function and diffusion capacity are associated with pulmonary arterial systolic pressure in the general population: The Rotterdam Study.

Loth DW, Lahousse L, Leening MJG, Krijthe BP, Felix JF, Gall H, Hofman A, Ghofrani HA, Franco OH, Stricker BH, Brusselle GG.

Respir Med. 2017 Nov;132:50-55. doi: 10.1016/j.rmed.2017.09.009. Epub 2017 Sep 21.

PMID:
29229105
31.

COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression.

Nedeljkovic I, Lahousse L, Carnero-Montoro E, Faiz A, Vonk JM, de Jong K, van der Plaat DA, van Diemen CC, van den Berge M, Obeidat M, Bossé Y, Nickle DC, Consortium BIOS, Uitterlinden AG, van Meurs JBJ, Stricker BHC, Brusselle GG, Postma DS, Boezen HM, van Duijn CM, Amin N.

Hum Mol Genet. 2018 Jan 15;27(2):396-405. doi: 10.1093/hmg/ddx390.

32.

The Rotterdam Study: 2018 update on objectives, design and main results.

Ikram MA, Brusselle GGO, Murad SD, van Duijn CM, Franco OH, Goedegebure A, Klaver CCW, Nijsten TEC, Peeters RP, Stricker BH, Tiemeier H, Uitterlinden AG, Vernooij MW, Hofman A.

Eur J Epidemiol. 2017 Sep;32(9):807-850. doi: 10.1007/s10654-017-0321-4. Epub 2017 Oct 24.

33.

DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients.

Seys LJM, Widagdo W, Verhamme FM, Kleinjan A, Janssens W, Joos GF, Bracke KR, Haagmans BL, Brusselle GG.

Clin Infect Dis. 2018 Jan 6;66(1):45-53. doi: 10.1093/cid/cix741.

PMID:
29020176
34.

microRNA profiling in lung tissue and bronchoalveolar lavage of cigarette smoke-exposed mice and in COPD patients: a translational approach.

Conickx G, Avila Cobos F, van den Berge M, Faiz A, Timens W, Hiemstra PS, Joos GF, Brusselle GG, Mestdagh P, Bracke KR.

Sci Rep. 2017 Oct 9;7(1):12871. doi: 10.1038/s41598-017-13265-8.

35.

Adherence to the 2015 Dutch dietary guidelines and risk of non-communicable diseases and mortality in the Rotterdam Study.

Voortman T, Kiefte-de Jong JC, Ikram MA, Stricker BH, van Rooij FJA, Lahousse L, Tiemeier H, Brusselle GG, Franco OH, Schoufour JD.

Eur J Epidemiol. 2017 Nov;32(11):993-1005. doi: 10.1007/s10654-017-0295-2. Epub 2017 Aug 19.

36.

Epidemiology and impact of chronic bronchitis in chronic obstructive pulmonary disease.

Lahousse L, Seys LJM, Joos GF, Franco OH, Stricker BH, Brusselle GG.

Eur Respir J. 2017 Aug 10;50(2). pii: 1602470. doi: 10.1183/13993003.02470-2016. Print 2017 Aug.

37.

Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure.

de Jong K, Vonk JM, Imboden M, Lahousse L, Hofman A, Brusselle GG, Probst-Hensch NM, Postma DS, Boezen HM.

Respir Res. 2017 Jul 24;18(1):142. doi: 10.1186/s12931-017-0625-7.

38.

The effects of lutein on respiratory health across the life course: A systematic review.

Melo van Lent D, Leermakers ETM, Darweesh SKL, Moreira EM, Tielemans MJ, Muka T, Vitezova A, Chowdhury R, Bramer WM, Brusselle GG, Felix JF, Kiefte-de Jong JC, Franco OH.

Clin Nutr ESPEN. 2016 Jun;13:e1-e7. doi: 10.1016/j.clnesp.2016.02.096. Epub 2016 Mar 26. Review.

PMID:
28531562
39.

Sputum Neutrophil Elastase as a Biomarker for Disease Activity in Bronchiectasis.

Brusselle GG, Van Braeckel E.

Am J Respir Crit Care Med. 2017 May 15;195(10):1289-1291. doi: 10.1164/rccm.201612-2476ED. No abstract available.

PMID:
28504604
40.

Association between lutein intake and lung function in adults: the Rotterdam Study.

Melo van Lent D, Leermakers ET, Hofman A, Stricker BH, Brusselle GG, Franco OH, Lahousse L, Kiefte-de Jong JC.

Br J Nutr. 2017 Mar;117(5):720-730. doi: 10.1017/S0007114517000319. Epub 2017 Apr 5.

PMID:
28376947
41.

Reply: Direct Detection of Circulating MicroRNAs Unveiled the Absence of MicroRNA-218-5p in Smoker Subjects.

Conickx G, Mestdagh P, Vandesompele J, Brusselle GG, Bracke KR.

Am J Respir Crit Care Med. 2017 Aug 15;196(4):533. doi: 10.1164/rccm.201701-0224LE. No abstract available.

PMID:
28257234
42.

Sex-Specific Genetic Risk Factors for Chronic Obstructive Pulmonary Disease.

Brusselle GG, Lahousse L.

Am J Respir Cell Mol Biol. 2017 Mar;56(3):281-282. doi: 10.1165/rcmb.2016-0399ED. No abstract available.

PMID:
28248137
43.

Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease.

Skronska-Wasek W, Mutze K, Baarsma HA, Bracke KR, Alsafadi HN, Lehmann M, Costa R, Stornaiuolo M, Novellino E, Brusselle GG, Wagner DE, Yildirim AÖ, Königshoff M.

Am J Respir Crit Care Med. 2017 Jul 15;196(2):172-185. doi: 10.1164/rccm.201605-0904OC.

PMID:
28245136
44.

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, Hokanson JE, Crapo JD, Castaldi PJ, Chase RP, Bartz TM, Heckbert SR, Psaty BM, Gharib SA, Zanen P, Lammers JW, Oudkerk M, Groen HJ, Locantore N, Tal-Singer R, Rennard SI, Vestbo J, Timens W, Paré PD, Latourelle JC, Dupuis J, O'Connor GT, Wilk JB, Kim WJ, Lee MK, Oh YM, Vonk JM, de Koning HJ, Leng S, Belinsky SA, Tesfaigzi Y, Manichaikul A, Wang XQ, Rich SS, Barr RG, Sparrow D, Litonjua AA, Bakke P, Gulsvik A, Lahousse L, Brusselle GG, Stricker BH, Uitterlinden AG, Ampleford EJ, Bleecker ER, Woodruff PG, Meyers DA, Qiao D, Lomas DA, Yim JJ, Kim DK, Hawrylkiewicz I, Sliwinski P, Hardin M, Fingerlin TE, Schwartz DA, Postma DS, MacNee W, Tobin MD, Silverman EK, Boezen HM, Cho MH; COPDGene Investigators; ECLIPSE Investigators; LifeLines Investigators; SPIROMICS Research Group; International COPD Genetics Network Investigators; UK BiLEVE Investigators; International COPD Genetics Consortium.

Nat Genet. 2017 Mar;49(3):426-432. doi: 10.1038/ng.3752. Epub 2017 Feb 6.

45.

Design of a frailty index among community living middle-aged and older people: The Rotterdam study.

Schoufour JD, Erler NS, Jaspers L, Kiefte-de Jong JC, Voortman T, Ziere G, Lindemans J, Klaver CC, Tiemeier H, Stricker B, Ikram AM, Laven JS, Brusselle GG, Rivadeneira F, Franco OH.

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Mucosal Immunol. 2017 Nov;10(6):1400-1411. doi: 10.1038/mi.2017.3. Epub 2017 Feb 1.

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Development of a Healthy Aging Score in the Population-Based Rotterdam Study: Evaluating Age and Sex Differences.

Jaspers L, Schoufour JD, Erler NS, Darweesh SK, Portegies ML, Sedaghat S, Lahousse L, Brusselle GG, Stricker BH, Tiemeier H, Ikram MA, Laven JS, Franco OH, Kavousi M.

J Am Med Dir Assoc. 2017 Mar 1;18(3):276.e1-276.e7. doi: 10.1016/j.jamda.2016.11.021. Epub 2017 Jan 18.

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Aschard H, Tobin MD, Hancock DB, Skurnik D, Sood A, James A, Vernon Smith A, Manichaikul AW, Campbell A, Prins BP, Hayward C, Loth DW, Porteous DJ, Strachan DP, Zeggini E, O'Connor GT, Brusselle GG, Boezen HM, Schulz H, Deary IJ, Hall IP, Rudan I, Kaprio J, Wilson JF, Wilk JB, Huffman JE, Hua Zhao J, de Jong K, Lyytikäinen LP, Wain LV, Jarvelin MR, Kähönen M, Fornage M, Polasek O, Cassano PA, Barr RG, Rawal R, Harris SE, Gharib SA, Enroth S, Heckbert SR, Lehtimäki T, Gyllensten U; Understanding Society Scientific Group, Jackson VE, Gudnason V, Tang W, Dupuis J, Soler Artigas M, Joshi AD, London SJ, Kraft P.

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J Exp Med. 2017 Feb;214(2):565. doi: 10.1084/jem.2016067501052017c. Epub 2017 Jan 9. No abstract available.

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End-stage cystic fibrosis lung disease is characterised by a diverse inflammatory pattern: an immunohistochemical analysis.

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Respir Res. 2017 Jan 10;18(1):10. doi: 10.1186/s12931-016-0489-2.

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