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Estrogen Receptor pathway activity score to predict clinical response or resistance to neo-adjuvant endocrine therapy in primary breast cancer.

Inda MA, Blok EJ, Kuppen PJK, Charehbili A, den Biezen-Timmermans EC, van Brussel A, Fruytier SE, Meershoek-Klein Kranenbarg E, Kloet SL, van der Burg B, Martens JWM, Sims AH, Turnbull AK, Dixon JM, Verhaegh W, Kroep JR, van de Velde CJH, van de Stolpe A.

Mol Cancer Ther. 2019 Nov 14. pii: molcanther.0318.2019. doi: 10.1158/1535-7163.MCT-19-0318. [Epub ahead of print]


Use of a new RNA next generation sequencing approach for the specific detection of virus infection in cells.

Brussel A, Brack K, Muth E, Zirwes R, Cheval J, Hebert C, Charpin JM, Marinaci A, Flan B, Ruppach H, Beurdeley P, Eloit M.

Biologicals. 2019 May;59:29-36. doi: 10.1016/j.biologicals.2019.03.008. Epub 2019 Apr 13.


Biopharmaceutical Industry Approaches to Facility Segregation for Viral Safety: An Effort from the Consortium on Adventitious Agent Contamination in Biomanufacturing.

Barone PW, Avgerinos S, Ballard R, Brussel A, Clark P, Dowd C, Gerentes L, Hart I, Keumurian FJ, Kindermann J, Leung JC, Ly N, Mink S, Minning S, Mullberg J, Murphy M, Nöske K, Parriott S, Shum B, Wiebe ME, Springs SL.

PDA J Pharm Sci Technol. 2019 Mar-Apr;73(2):191-203. doi: 10.5731/pdajpst.2018.008862. Epub 2018 Oct 25.


The Prognostic PDE4D7 Score in a Diagnostic Biopsy Prostate Cancer Patient Cohort with Longitudinal Biological Outcomes.

van Strijp D, de Witz C, Vos PC, den Biezen-Timmermans E, van Brussel A, Wrobel J, Baillie GS, Tennstedt P, Schlomm T, Heitkötter B, Huss S, Bögemann M, Houslay MD, Bangma C, Semjonow A, Hoffmann R.

Prostate Cancer. 2018 Jul 26;2018:5821616. doi: 10.1155/2018/5821616. eCollection 2018.


Effectiveness of different pre-treatments in recovering pre-burial isotopic ratios of charred plants.

Brinkkemper O, Braadbaart F, van Os B, van Hoesel A, van Brussel AAN, Fernandes R.

Rapid Commun Mass Spectrom. 2018 Feb 15;32(3):251-261. doi: 10.1002/rcm.8033.


Validation of Cyclic Adenosine Monophosphate Phosphodiesterase-4D7 for its Independent Contribution to Risk Stratification in a Prostate Cancer Patient Cohort with Longitudinal Biological Outcomes.

Alves de Inda M, van Strijp D, den Biezen-Timmermans E, van Brussel A, Wrobel J, van Zon H, Vos P, Baillie GS, Tennstedt P, Schlomm T, Houslay MD, Bangma C, Hoffmann R.

Eur Urol Focus. 2018 Apr;4(3):376-384. doi: 10.1016/j.euf.2017.05.010. Epub 2017 Jun 13.


Optical imaging of pre-invasive breast cancer with a combination of VHHs targeting CAIX and HER2 increases contrast and facilitates tumour characterization.

Kijanka MM, van Brussel AS, van der Wall E, Mali WP, van Diest PJ, van Bergen En Henegouwen PM, Oliveira S.

EJNMMI Res. 2016 Dec;6(1):14. doi: 10.1186/s13550-016-0166-y. Epub 2016 Feb 10.


Hypoxia-Targeting Fluorescent Nanobodies for Optical Molecular Imaging of Pre-Invasive Breast Cancer.

van Brussel AS, Adams A, Oliveira S, Dorresteijn B, El Khattabi M, Vermeulen JF, van der Wall E, Mali WP, Derksen PW, van Diest PJ, van Bergen En Henegouwen PM.

Mol Imaging Biol. 2016 Aug;18(4):535-44. doi: 10.1007/s11307-015-0909-6.


Treatment of late-stage syphilis.

van Brussel AS, Landman GW.

JAMA. 2015 Mar 3;313(9):968-9. doi: 10.1001/jama.2015.0669. No abstract available.


The potential of hypoxia markers as target for breast molecular imaging--a systematic review and meta-analysis of human marker expression.

Adams A, van Brussel AS, Vermeulen JF, Mali WP, van der Wall E, van Diest PJ, Elias SG.

BMC Cancer. 2013 Nov 10;13:538. doi: 10.1186/1471-2407-13-538. Review.


Molecular imaging with a fluorescent antibody targeting carbonic anhydrase IX can successfully detect hypoxic ductal carcinoma in situ of the breast.

van Brussel AS, Adams A, Vermeulen JF, Oliveira S, van der Wall E, Mali WP, van Diest PJ, van Bergen En Henegouwen PM.

Breast Cancer Res Treat. 2013 Jul;140(2):263-72. doi: 10.1007/s10549-013-2635-6. Epub 2013 Jul 17.


High NaCl concentrations induce the nod genes of Rhizobium tropici CIAT899 in the absence of flavonoid inducers.

Guasch-Vidal B, Estévez J, Dardanelli MS, Soria-Díaz ME, de Córdoba FF, Balog CI, Manyani H, Gil-Serrano A, Thomas-Oates J, Hensbergen PJ, Deelder AM, Megías M, van Brussel AA.

Mol Plant Microbe Interact. 2013 Apr;26(4):451-60. doi: 10.1094/MPMI-09-12-0213-R.


Near-infrared fluorescence molecular imaging of ductal carcinoma in situ with CD44v6-specific antibodies in mice: a preclinical study.

Vermeulen JF, van Brussel AS, Adams A, Mali WP, van der Wall E, van Diest PJ, Derksen PW.

Mol Imaging Biol. 2013 Jun;15(3):290-8. doi: 10.1007/s11307-012-0605-8.


Immunophenotyping invasive breast cancer: paving the road for molecular imaging.

Vermeulen JF, van Brussel AS, van der Groep P, Morsink FH, Bult P, van der Wall E, van Diest PJ.

BMC Cancer. 2012 Jun 13;12:240. doi: 10.1186/1471-2407-12-240.


Expression of nuclear FIH independently predicts overall survival of clear cell renal cell carcinoma patients.

Kroeze SG, Vermaat JS, van Brussel A, van Melick HH, Voest EE, Jonges TG, van Diest PJ, Hinrichs J, Bosch JL, Jans JJ.

Eur J Cancer. 2010 Dec;46(18):3375-82. doi: 10.1016/j.ejca.2010.07.018. Epub 2010 Aug 13.


Genetic analysis of von Hippel-Lindau disease.

Nordstrom-O'Brien M, van der Luijt RB, van Rooijen E, van den Ouweland AM, Majoor-Krakauer DF, Lolkema MP, van Brussel A, Voest EE, Giles RH.

Hum Mutat. 2010 May;31(5):521-37. doi: 10.1002/humu.21219.


Nonpathogenesis of simian immunodeficiency virus infection is associated with reduced inflammation and recruitment of plasmacytoid dendritic cells to lymph nodes, not to lack of an interferon type I response, during the acute phase.

Campillo-Gimenez L, Laforge M, Fay M, Brussel A, Cumont MC, Monceaux V, Diop O, Lévy Y, Hurtrel B, Zaunders J, Corbeil J, Elbim C, Estaquier J.

J Virol. 2010 Feb;84(4):1838-46. doi: 10.1128/JVI.01496-09. Epub 2009 Nov 25.


Sinorhizobium fredii HH103 cgs mutants are unable to nodulate determinate- and indeterminate nodule-forming legumes and overproduce an altered EPS.

Crespo-Rivas JC, Margaret I, Hidalgo A, Buendía-Clavería AM, Ollero FJ, López-Baena FJ, del Socorro Murdoch P, Rodríguez-Carvajal MA, Soria-Díaz ME, Reguera M, Lloret J, Sumpton DP, Mosely JA, Thomas-Oates JE, van Brussel AA, Gil-Serrano A, Vinardell JM, Ruiz-Sainz JE.

Mol Plant Microbe Interact. 2009 May;22(5):575-88. doi: 10.1094/MPMI-22-5-0575.


Different and new Nod factors produced by Rhizobium tropici CIAT899 following Na+ stress.

Estévez J, Soria-Díaz ME, de Córdoba FF, Morón B, Manyani H, Gil A, Thomas-Oates J, van Brussel AA, Dardanelli MS, Sousa C, Megías M.

FEMS Microbiol Lett. 2009 Apr;293(2):220-31. doi: 10.1111/j.1574-6968.2009.01540.x. Epub 2009 Mar 2.


Lack of endogenous TRIM5alpha-mediated restriction in rhesus macaque dendritic cells.

Arhel NJ, Nisole S, Carthagena L, Coutant F, Souque P, Brussel A, Estaquier J, Charneau P.

Blood. 2008 Nov 1;112(9):3772-6. doi: 10.1182/blood-2008-04-151761. Epub 2008 Aug 14.


Synthesis and stereochemistry-activity relationship of small bacteriocin, an autoinducer of the symbiotic nitrogen-fixing bacterium Rhizobium leguminosarum.

Yajima A, van Brussel AA, Schripsema J, Nukada T, Yabuta G.

Org Lett. 2008 May 15;10(10):2047-50. doi: 10.1021/ol8005198. Epub 2008 Apr 11.


A novel polar surface polysaccharide from Rhizobium leguminosarum binds host plant lectin.

Laus MC, Logman TJ, Lamers GE, Van Brussel AA, Carlson RW, Kijne JW.

Mol Microbiol. 2006 Mar;59(6):1704-13.


Exopolysaccharide structure is not a determinant of host-plant specificity in nodulation of Vicia sativa roots.

Laus MC, van Brussel AA, Kijne JW.

Mol Plant Microbe Interact. 2005 Nov;18(11):1123-9.


Quantification of HFV-integrated DNA in human cells by Alu-LTR real-time PCR.

Delelis O, Brussel A, Sonigo P.

Methods Mol Biol. 2005;304:155-70.


Alu-LTR real-time nested PCR assay for quantifying integrated HIV-1 DNA.

Brussel A, Delelis O, Sonigo P.

Methods Mol Biol. 2005;304:139-54.


Cell cycle regulation of human immunodeficiency virus type 1 integration in T cells: antagonistic effects of nuclear envelope breakdown and chromatin condensation.

Mannioui A, Schiffer C, Felix N, Nelson E, Brussel A, Sonigo P, Gluckman JC, Canque B.

Virology. 2004 Nov 10;329(1):77-88.


Involvement of exo5 in production of surface polysaccharides in Rhizobium leguminosarum and its role in nodulation of Vicia sativa subsp. nigra.

Laus MC, Logman TJ, Van Brussel AA, Carlson RW, Azadi P, Gao MY, Kijne JW.

J Bacteriol. 2004 Oct;186(19):6617-25.


Accumulation of lipochitin oligosaccharides and NodD-activating compounds in an efficient plant--Rhizobium nodulation assay.

Tak T, van Spronsen PC, Kijne JW, van Brussel AA, Boot KJ.

Mol Plant Microbe Interact. 2004 Jul;17(7):816-23.


A catalogue of molecular, physiological and symbiotic properties of soybean-nodulating rhizobial strains from different soybean cropping areas of China.

Thomas-Oates J, Bereszczak J, Edwards E, Gill A, Noreen S, Zhou JC, Chen MZ, Miao LH, Xie FL, Yang JK, Zhou Q, Yang SS, Li XH, Wang L, Spaink HP, Schlaman HR, Harteveld M, Díaz CL, van Brussel AA, Camacho M, Rodríguez-Navarro DN, Santamaría C, Temprano F, Acebes JM, Bellogín RA, Buendía-Clavería AM, Cubo MT, Espuny MR, Gil AM, Gutiérrez R, Hidalgo A, López-Baena FJ, Madinabeitia N, Medina C, Ollero FJ, Vinardell JM, Ruiz-Sainz JE.

Syst Appl Microbiol. 2003 Sep;26(3):453-65.


Longitudinal monitoring of 2-long terminal repeat circles in peripheral blood mononuclear cells from patients with chronic HIV-1 infection.

Brussel A, Mathez D, Broche-Pierre S, Lancar R, Calvez T, Sonigo P, Leibowitch J.

AIDS. 2003 Mar 28;17(5):645-52.


Salicylic acid inhibits indeterminate-type nodulation but not determinate-type nodulation.

van Spronsen PC, Tak T, Rood AM, van Brussel AA, Kijne JW, Boot KJ.

Mol Plant Microbe Interact. 2003 Jan;16(1):83-91.


Effect of pH and soybean cultivars on the quantitative analyses of soybean rhizobia populations.

Yang SS, Bellogín RA, Buendía A, Camacho M, Chen M, Cubo T, Daza A, Díaz CL, Espuny MR, Gutiérrez R, Harteveld M, Li XH, Lyra MC, Madinabeitia N, Medina C, Miao L, Ollero FJ, Olsthoorn MM, Rodríguez DN, Santamaría C, Schlaman HR, Spaink HP, Temprano F, Thomas-Oates JE, Van Brussel AA, Vinardell JM, Xie F, Yang J, Zhang HY, Zhen J, Zhou J, Ruiz-Sainz JE.

J Biotechnol. 2001 Oct 4;91(2-3):243-55.


Sequences and predicted structures of chimpanzee STRL33 (Bonzo) and gpr15 (BOB).

Brussel A, Prétet JL, Girard M, Butor C.

AIDS Res Hum Retroviruses. 1999 Sep 20;15(14):1315-9. No abstract available.


Two alleles for rhesus macaque GPR15 (BOB).

Prétet JL, Brussel A, Guillet JG, Butor C.

AIDS Res Hum Retroviruses. 1999 Jul 1;15(10):945-7. No abstract available.


Bacteriocin small of Rhizobium leguminosarum belongs to the class of N-acyl-L-homoserine lactone molecules, known as autoinducers and as quorum sensing co-transcription factors.

Schripsema J, de Rudder KE, van Vliet TB, Lankhorst PP, de Vroom E, Kijne JW, van Brussel AA.

J Bacteriol. 1996 Jan;178(2):366-71.


Uridine, a cell division factor in pea roots.

Smit G, de Koster CC, Schripsema J, Spaink HP, van Brussel AA, Kijne JW.

Plant Mol Biol. 1995 Nov;29(4):869-73.


Induction of nodule primordia on Phaseolus and Acacia by lipo-chitin oligosaccharide nodulation signals from broad-host-range Rhizobium strain GRH2.

López-Lara IM, van der Drift KM, van Brussel AA, Haverkamp J, Lugtenberg BJ, Thomas-Oates JE, Spaink HP.

Plant Mol Biol. 1995 Nov;29(3):465-77.


Early nodulin gene expression during Nod factor-induced processes in Vicia sativa.

Vijn I, Martinez-Abarca F, Yang WC, das Neves L, van Brussel A, van Kammen A, Bisseling T.

Plant J. 1995 Jul;8(1):111-9.


Cell wall degradation during infection thread formation by the root nodule bacterium Rhizobium leguminosarum is a two-step process.

van Spronsen PC, Bakhuizen R, van Brussel AA, Kijne JW.

Eur J Cell Biol. 1994 Jun;64(1):88-94.


The structures and biological activities of the lipo-oligosaccharide nodulation signals produced by type I and II strains of Bradyrhizobium japonicum.

Carlson RW, Sanjuan J, Bhat UR, Glushka J, Spaink HP, Wijfjes AH, van Brussel AA, Stokkermans TJ, Peters NK, Stacey G.

J Biol Chem. 1993 Aug 25;268(24):18372-81.


Induction of pre-infection thread structures in the leguminous host plant by mitogenic lipo-oligosaccharides of Rhizobium.

van Brussel AA, Bakhuizen R, van Spronsen PC, Spaink HP, Tak T, Lugtenberg BJ, Kijne JW.

Science. 1992 Jul 3;257(5066):70-2.


Activation of flavonoid biosynthesis in roots of Vicia sativa subsp. nigra plants by inoculation with Rhizobium leguminosarum biovar viciae.

Recourt K, van Tunen AJ, Mur LA, van Brussel AA, Lugtenberg BJ, Kijne JW.

Plant Mol Biol. 1992 Jun;19(3):411-20.


Major flavonoids in uninoculated and inoculated roots of Vicia sativa subsp. nigra are four conjugates of the nodulation gene-inhibitor kaempferol.

Recourt K, Verkerke M, Schripsema J, van Brussel AA, Lugtenberg BJ, Kijne JW.

Plant Mol Biol. 1992 Feb;18(3):505-13.


A novel highly unsaturated fatty acid moiety of lipo-oligosaccharide signals determines host specificity of Rhizobium.

Spaink HP, Sheeley DM, van Brussel AA, Glushka J, York WS, Tak T, Geiger O, Kennedy EP, Reinhold VN, Lugtenberg BJ.

Nature. 1991 Nov 14;354(6349):125-30.


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