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Items: 1 to 50 of 52

1.

Glucocorticoid-Induced Leucine Zipper: A Novel Anti-inflammatory Molecule.

Bereshchenko O, Migliorati G, Bruscoli S, Riccardi C.

Front Pharmacol. 2019 Mar 27;10:308. doi: 10.3389/fphar.2019.00308. eCollection 2019. Review.

2.

Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages.

Hoppstädter J, Diesel B, Linnenberger R, Hachenthal N, Flamini S, Minet M, Leidinger P, Backes C, Grässer F, Meese E, Bruscoli S, Riccardi C, Huwer H, Kiemer AK.

Front Immunol. 2019 Jan 22;9:3111. doi: 10.3389/fimmu.2018.03111. eCollection 2018.

3.

Probing Internalization Effects and Biocompatibility of Ultrasmall Zirconium Metal-Organic Frameworks UiO-66 NP in U251 Glioblastoma Cancer Cells.

Arcuri C, Monarca L, Ragonese F, Mecca C, Bruscoli S, Giovagnoli S, Donato R, Bereshchenko O, Fioretti B, Costantino F.

Nanomaterials (Basel). 2018 Oct 23;8(11). pii: E867. doi: 10.3390/nano8110867.

4.

Glucocorticoid-Induced Leucine Zipper Inhibits Interferon-Gamma Production in B Cells and Suppresses Colitis in Mice.

Bruscoli S, Sorcini D, Flamini S, Gagliardi A, Adamo F, Ronchetti S, Migliorati G, Bereshchenko O, Riccardi C.

Front Immunol. 2018 Jul 23;9:1720. doi: 10.3389/fimmu.2018.01720. eCollection 2018.

5.

Defining the role of glucocorticoids in inflammation.

Ronchetti S, Migliorati G, Bruscoli S, Riccardi C.

Clin Sci (Lond). 2018 Jul 31;132(14):1529-1543. doi: 10.1042/CS20171505. Print 2018 Jul 31. Review.

PMID:
30065045
6.

Glucocorticoids, Sex Hormones, and Immunity.

Bereshchenko O, Bruscoli S, Riccardi C.

Front Immunol. 2018 Jun 12;9:1332. doi: 10.3389/fimmu.2018.01332. eCollection 2018. Review.

7.

PP242 Counteracts Glioblastoma Cell Proliferation, Migration, Invasiveness and Stemness Properties by Inhibiting mTORC2/AKT.

Mecca C, Giambanco I, Bruscoli S, Bereshchenko O, Fioretti B, Riccardi C, Donato R, Arcuri C.

Front Cell Neurosci. 2018 Apr 10;12:99. doi: 10.3389/fncel.2018.00099. eCollection 2018.

8.

Wnt/β-Catenin Signaling Induces Integrin α4β1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice.

Sorcini D, Bruscoli S, Frammartino T, Cimino M, Mazzon E, Galuppo M, Bramanti P, Al-Banchaabouchi M, Farley D, Ermakova O, Britanova O, Izraelson M, Chudakov D, Biagioli M, Sportoletti P, Flamini S, Raspa M, Scavizzi F, Nerlov C, Migliorati G, Riccardi C, Bereshchenko O.

J Immunol. 2017 Nov 1;199(9):3031-3041. doi: 10.4049/jimmunol.1700247. Epub 2017 Sep 22.

9.

Aberrant expression of β-catenin in CD4+ T cells isolated from primary progressive multiple sclerosis patients.

Giacoppo S, Bereshchenko O, Bruscoli S, Riccardi C, Bramanti P, Mazzon E.

Neurosci Lett. 2017 Jul 13;653:159-162. doi: 10.1016/j.neulet.2017.05.057. Epub 2017 May 31.

PMID:
28578105
10.

Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-β1.

Carceller E, Ballegeer M, Deckers J, Riccardi C, Bruscoli S, Hochepied T, Libert C, Pérez P.

Sci Rep. 2016 Dec 9;6:38825. doi: 10.1038/srep38825.

11.

Induction of Glucocorticoid-induced Leucine Zipper (GILZ) Contributes to Anti-inflammatory Effects of the Natural Product Curcumin in Macrophages.

Hoppstädter J, Hachenthal N, Valbuena-Perez JV, Lampe S, Astanina K, Kunze MM, Bruscoli S, Riccardi C, Schmid T, Diesel B, Kiemer AK.

J Biol Chem. 2016 Oct 28;291(44):22949-22960. Epub 2016 Sep 14.

12.

Is β-catenin neutralization cross-involved in the mechanisms mediated by natalizumab action?

Galuppo M, Mazzon E, Giacoppo S, Bereshchenko O, Bruscoli S, Riccardi C, Bramanti P.

Curr Mol Med. 2015;15(10):990-3.

PMID:
26592242
13.

Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice.

Bruscoli S, Biagioli M, Sorcini D, Frammartino T, Cimino M, Sportoletti P, Mazzon E, Bereshchenko O, Riccardi C.

Blood. 2015 Oct 8;126(15):1790-801. doi: 10.1182/blood-2015-03-631580. Epub 2015 Aug 14.

14.

Glucocorticoid-induced leucine zipper: a critical factor in macrophage endotoxin tolerance.

Hoppstädter J, Kessler SM, Bruscoli S, Huwer H, Riccardi C, Kiemer AK.

J Immunol. 2015 Jun 15;194(12):6057-67. doi: 10.4049/jimmunol.1403207. Epub 2015 May 11.

15.

The role and effects of glucocorticoid-induced leucine zipper in the context of inflammation resolution.

Vago JP, Tavares LP, Garcia CC, Lima KM, Perucci LO, Vieira ÉL, Nogueira CR, Soriani FM, Martins JO, Silva PM, Gomes KB, Pinho V, Bruscoli S, Riccardi C, Beaulieu E, Morand EF, Teixeira MM, Sousa LP.

J Immunol. 2015 May 15;194(10):4940-50. doi: 10.4049/jimmunol.1401722. Epub 2015 Apr 15.

16.

Glucocorticoid-induced leucine zipper (GILZ) controls inflammation and tissue damage after spinal cord injury.

Mazzon E, Bruscoli S, Galuppo M, Biagioli M, Sorcini D, Bereshchenko O, Fiorucci C, Migliorati G, Bramanti P, Riccardi C.

CNS Neurosci Ther. 2014 Nov;20(11):973-81. doi: 10.1111/cns.12315. Epub 2014 Aug 21.

17.

Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells.

Benkhoucha M, Molnarfi N, Dunand-Sauthier I, Merkler D, Schneiter G, Bruscoli S, Riccardi C, Tabata Y, Funakoshi H, Nakamura T, Reith W, Santiago-Raber ML, Lalive PH.

J Immunol. 2014 Sep 15;193(6):2743-52. doi: 10.4049/jimmunol.1302338. Epub 2014 Aug 11.

18.

Transcriptional regulation of kinases downstream of the T cell receptor: another immunomodulatory mechanism of glucocorticoids.

Petrillo MG, Fettucciari K, Montuschi P, Ronchetti S, Cari L, Migliorati G, Mazzon E, Bereshchenko O, Bruscoli S, Nocentini G, Riccardi C.

BMC Pharmacol Toxicol. 2014 Jul 3;15:35. doi: 10.1186/2050-6511-15-35.

19.

Recombinant long-glucocorticoid-induced leucine zipper (L-GILZ) protein restores the control of proliferation in gilz KO spermatogonia.

Venanzi A, Di Sante M, Bruscoli S, Biagioli M, Sorcini D, Cimino M, Frammartino T, Bereshchenko O, Franconi F, Riccardi C.

Eur J Pharm Sci. 2014 Oct 15;63:22-8. doi: 10.1016/j.ejps.2014.06.013. Epub 2014 Jun 30.

PMID:
24993177
20.

GILZ promotes production of peripherally induced Treg cells and mediates the crosstalk between glucocorticoids and TGF-β signaling.

Bereshchenko O, Coppo M, Bruscoli S, Biagioli M, Cimino M, Frammartino T, Sorcini D, Venanzi A, Di Sante M, Riccardi C.

Cell Rep. 2014 Apr 24;7(2):464-475. doi: 10.1016/j.celrep.2014.03.004. Epub 2014 Apr 3.

21.

Glucocorticoid-induced leucine zipper (GILZ) over-expression in T lymphocytes inhibits inflammation and tissue damage in spinal cord injury.

Esposito E, Bruscoli S, Mazzon E, Paterniti I, Coppo M, Velardi E, Cuzzocrea S, Riccardi C.

Neurotherapeutics. 2012 Jan;9(1):210-25. doi: 10.1007/s13311-011-0084-7.

22.

Long glucocorticoid-induced leucine zipper (L-GILZ) protein interacts with ras protein pathway and contributes to spermatogenesis control.

Bruscoli S, Velardi E, Di Sante M, Bereshchenko O, Venanzi A, Coppo M, Berno V, Mameli MG, Colella R, Cavaliere A, Riccardi C.

J Biol Chem. 2012 Jan 6;287(2):1242-51. doi: 10.1074/jbc.M111.316372. Epub 2011 Nov 22.

23.

GITR gene deletion and GITR-FC soluble protein administration inhibit multiple organ failure induced by zymosan.

Galuppo M, Nocentini G, Mazzon E, Ronchetti S, Esposito E, Riccardi L, Di Paola R, Bruscoli S, Riccardi C, Cuzzocrea S.

Shock. 2011 Sep;36(3):263-71. doi: 10.1097/SHK.0b013e3182262c48.

PMID:
21654556
24.

The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice.

Galuppo M, Nocentini G, Mazzon E, Ronchetti S, Esposito E, Riccardi L, Sportoletti P, Di Paola R, Bruscoli S, Riccardi C, Cuzzocrea S.

Br J Pharmacol. 2011 Mar;162(5):1186-201. doi: 10.1111/j.1476-5381.2010.01123.x.

25.

Efficacy of very-low-dose betamethasone on neurological symptoms in ataxia-telangiectasia.

Broccoletti T, Del Giudice E, Cirillo E, Vigliano I, Giardino G, Ginocchio VM, Bruscoli S, Riccardi C, Pignata C.

Eur J Neurol. 2011 Apr;18(4):564-70. doi: 10.1111/j.1468-1331.2010.03203.x. Epub 2010 Sep 14.

PMID:
20840352
26.

Glucocorticoid-induced activation of caspase-8 protects the glucocorticoid-induced protein Gilz from proteasomal degradation and induces its binding to SUMO-1 in murine thymocytes.

Delfino DV, Spinicelli S, Pozzesi N, Pierangeli S, Velardi E, Bruscoli S, Martelli MP, Pettirossi V, Falchi L, Kang TB, Riccardi C.

Cell Death Differ. 2011 Jan;18(1):183-90. doi: 10.1038/cdd.2010.86. Epub 2010 Jul 30.

27.

Glucocorticoid-induced leucine zipper (GILZ) and long GILZ inhibit myogenic differentiation and mediate anti-myogenic effects of glucocorticoids.

Bruscoli S, Donato V, Velardi E, Di Sante M, Migliorati G, Donato R, Riccardi C.

J Biol Chem. 2010 Apr 2;285(14):10385-96. doi: 10.1074/jbc.M109.070136. Epub 2010 Feb 2.

28.

Silymarin suppress CD4+ T cell activation and proliferation: effects on NF-kappaB activity and IL-2 production.

Gharagozloo M, Velardi E, Bruscoli S, Agostini M, Di Sante M, Donato V, Amirghofran Z, Riccardi C.

Pharmacol Res. 2010 May;61(5):405-9. doi: 10.1016/j.phrs.2009.12.017. Epub 2010 Jan 7.

PMID:
20056147
29.

PPAR-alpha contributes to the anti-inflammatory activity of 17beta-estradiol.

Crisafulli C, Bruscoli S, Esposito E, Mazzon E, Di Paola R, Genovese T, Bramanti P, Migliorati G, Cuzzocrea S.

J Pharmacol Exp Ther. 2009 Dec;331(3):796-807. doi: 10.1124/jpet.109.156646. Epub 2009 Sep 15.

PMID:
19755663
30.

Involvement of cPLA2 inhibition in dexamethasone-induced thymocyte apoptosis.

Cinque B, Fanini D, Di Marzio L, Palumbo P, La Torre C, Donato V, Velardi E, Bruscoli S, Riccardi C, Cifone MG.

Int J Immunopathol Pharmacol. 2008 Jul-Sep;21(3):539-51.

PMID:
18831921
31.

Peroxisome proliferator-activated receptor-alpha modulates the anti-inflammatory effect of glucocorticoids in a model of inflammatory bowel disease in mice.

Riccardi L, Mazzon E, Bruscoli S, Esposito E, Crisafulli C, Di Paola R, Caminiti R, Riccardi C, Cuzzocrea S.

Shock. 2009 Mar;31(3):308-16. doi: 10.1097/SHK.0b013e31818339e7.

PMID:
18665053
32.

Peroxisome proliferator-activated receptor-alpha contributes to the anti-inflammatory activity of glucocorticoids.

Cuzzocrea S, Bruscoli S, Mazzon E, Crisafulli C, Donato V, Di Paola R, Velardi E, Esposito E, Nocentini G, Riccardi C.

Mol Pharmacol. 2008 Feb;73(2):323-37. Epub 2007 Nov 5.

PMID:
17984196
33.

Endothelial dysfunction in vivo is related to monocyte resistin mRNA expression.

Lupattelli G, Marchesi S, Ronti T, Lombardini R, Bruscoli S, Bianchini R, Vaudo G, Riccardi C, Mannarino E.

J Clin Pharm Ther. 2007 Aug;32(4):373-9.

PMID:
17635339
34.

Glucocorticoid-induced leucine zipper (GILZ)/NF-kappaB interaction: role of GILZ homo-dimerization and C-terminal domain.

Di Marco B, Massetti M, Bruscoli S, Macchiarulo A, Di Virgilio R, Velardi E, Donato V, Migliorati G, Riccardi C.

Nucleic Acids Res. 2007;35(2):517-28. Epub 2006 Dec 14.

35.

Estrogen receptor antagonist fulvestrant (ICI 182,780) inhibits the anti-inflammatory effect of glucocorticoids.

Cuzzocrea S, Bruscoli S, Crisafulli C, Mazzon E, Agostini M, Muià C, Esposito E, Di Virgilio R, Meli R, Vegeto E, Maggi A, Riccardi C.

Mol Pharmacol. 2007 Jan;71(1):132-44. Epub 2006 Oct 11.

PMID:
17035596
36.

GITR modulates innate and adaptive mucosal immunity during the development of experimental colitis in mice.

Santucci L, Agostini M, Bruscoli S, Mencarelli A, Ronchetti S, Ayroldi E, Morelli A, Baldoni M, Riccardi C.

Gut. 2007 Jan;56(1):52-60. Epub 2006 Jun 8.

37.

Genomic and non-genomic effects of different glucocorticoids on mouse thymocyte apoptosis.

Bruscoli S, Di Virgilio R, Donato V, Velardi E, Baldoni M, Marchetti C, Migliorati G, Riccardi C.

Eur J Pharmacol. 2006 Jan 4;529(1-3):63-70. Epub 2005 Dec 1.

PMID:
16325174
38.

Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis.

Cuzzocrea S, Ayroldi E, Di Paola R, Agostini M, Mazzon E, Bruscoli S, Genovese T, Ronchetti S, Caputi AP, Riccardi C.

FASEB J. 2005 Aug;19(10):1253-65.

PMID:
16051692
39.

Synthesis and evaluation of anti-apoptotic activity of L-carnitine cyclic analogues and amino acid derivatives.

Fringuelli R, Utrilla Navarro MP, Milanese L, Bruscoli S, Schiaffella F, Riccardi C, De Simone C.

Farmaco. 2004 Apr;59(4):271-7.

PMID:
15081344
40.

Apoptosis of human primary B lymphocytes is inhibited by N-acetyl-L-cysteine.

Rosati E, Sabatini R, Ayroldi E, Tabilio A, Bartoli A, Bruscoli S, Simoncelli C, Rossi R, Marconi P.

J Leukoc Biol. 2004 Jul;76(1):152-61. Epub 2004 Apr 1.

PMID:
14726501
41.

GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations.

Ronchetti S, Zollo O, Bruscoli S, Agostini M, Bianchini R, Nocentini G, Ayroldi E, Riccardi C.

Eur J Immunol. 2004 Mar;34(3):613-622. doi: 10.1002/eji.200324804.

42.

Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10.

Berrebi D, Bruscoli S, Cohen N, Foussat A, Migliorati G, Bouchet-Delbos L, Maillot MC, Portier A, Couderc J, Galanaud P, Peuchmaur M, Riccardi C, Emilie D.

Blood. 2003 Jan 15;101(2):729-38. Epub 2002 Sep 12.

PMID:
12393603
43.

Molecular mechanisms of immunomodulatory activity of glucocorticoids.

Riccardi C, Bruscoli S, Migliorati G.

Pharmacol Res. 2002 May;45(5):361-8. Review.

PMID:
12123623
44.

Induction of apoptosis by 1,4-benzothiazine analogs in mouse thymocytes.

Marchetti C, Ulisse S, Bruscoli S, Russo FP, Migliorati G, Schiaffella F, Cifone MG, Riccardi C, Fringuelli R.

J Pharmacol Exp Ther. 2002 Mar;300(3):1053-62.

PMID:
11861815
45.

GILZ, a glucocorticoid hormone induced gene, modulates T lymphocytes activation and death through interaction with NF-kB.

Riccardi C, Bruscoli S, Ayroldi E, Agostini M, Migliorati G.

Adv Exp Med Biol. 2001;495:31-9. No abstract available.

PMID:
11774584
46.
47.

Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB.

Ayroldi E, Migliorati G, Bruscoli S, Marchetti C, Zollo O, Cannarile L, D'Adamio F, Riccardi C.

Blood. 2001 Aug 1;98(3):743-53.

PMID:
11468175
48.

Cloning, chromosomal assignment and tissue distribution of human GILZ, a glucocorticoid hormone-induced gene.

Cannarile L, Zollo O, D'Adamio F, Ayroldi E, Marchetti C, Tabilio A, Bruscoli S, Riccardi C.

Cell Death Differ. 2001 Feb;8(2):201-3. No abstract available.

PMID:
11313722
49.

Differentiation of Ly49s-positive or -negative natural killer cells is inhibited by anti-H-2b monoclonal antibodies acting at the level of bone marrow progenitors from B6 mice.

Delfino DV, Salcedo M, Marco BD, Ayroldi E, Nocentini G, Bruscoli S, Brunetti L, Ljunggren HG, Riccardi C.

Cell Growth Differ. 2001 Jan;12(1):51-60.

50.

Glucocorticoid hormones in the regulation of cell death.

Riccardi C, Zollo O, Nocentini G, Bruscoli S, Bartoli A, D'Adamio F, Cannarile L, Delfino D, Ayroldi E, Migliorati G.

Therapie. 2000 Jan-Feb;55(1):165-9. Review.

PMID:
10860020

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