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Items: 1 to 50 of 89

1.

Regulation of cardiac fibroblast collagen synthesis by adenosine: roles for Epac and PI3K.

Villarreal F, Epperson SA, Ramirez-Sanchez I, Yamazaki KG, Brunton LL.

Am J Physiol Cell Physiol. 2009 May;296(5):C1178-84. doi: 10.1152/ajpcell.00291.2008. Epub 2009 Mar 11.

2.

Adenosine receptors and second messenger signaling pathways in rat cardiac fibroblasts.

Epperson SA, Brunton LL, Ramirez-Sanchez I, Villarreal F.

Am J Physiol Cell Physiol. 2009 May;296(5):C1171-7. doi: 10.1152/ajpcell.00290.2008. Epub 2009 Feb 25.

3.

Endothelin downregulates SERCA2 gene and protein expression in adult rat ventricular myocytes: regulation by pertussis toxin-sensitive Gi protein and cAMP.

Hilal-Dandan R, He H, Martin JL, Brunton LL, Dillmann WH.

Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H728-34. doi: 10.1152/ajpheart.00584.2008. Epub 2009 Jan 16.

4.

Who's afraid of ligand-macromolecule interactions in complex physiological systems?

Shankley N, Cox BF, Brunton LL.

Mol Interv. 2006 Dec;6(6):296-9. No abstract available.

PMID:
17200455
5.

NIGMS-sponsored integrative and organ systems pharmacology: synopsis of the 2005 experience/anticipation of the 2006 short courses.

Bylund DB, Brunton LL, Cobbett PJ, Persky AM, Preusch PC.

Mol Interv. 2005 Dec;5(6):330-3. No abstract available.

PMID:
16394246
6.

A positive feedback loop contributes to the deleterious effects of angiotensin.

Brunton LL.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14483-4. Epub 2005 Oct 3. No abstract available.

7.

Lysophosphatidic acid induces hypertrophy of neonatal cardiac myocytes via activation of Gi and Rho.

Hilal-Dandan R, Means CK, Gustafsson AB, Morissette MR, Adams JW, Brunton LL, Heller Brown J.

J Mol Cell Cardiol. 2004 Apr;36(4):481-93.

PMID:
15081308
8.

Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit.

Akamine P, Madhusudan, Brunton LL, Ou HD, Canaves JM, Xuong NH, Taylor SS.

Biochemistry. 2004 Jan 13;43(1):85-96.

PMID:
14705934
9.

PDE4: arrested at the border.

Brunton LL.

Sci STKE. 2003 Oct 14;2003(204):PE44. Review.

PMID:
14560046
10.

Modeling beta-adrenergic control of cardiac myocyte contractility in silico.

Saucerman JJ, Brunton LL, Michailova AP, McCulloch AD.

J Biol Chem. 2003 Nov 28;278(48):47997-8003. Epub 2003 Sep 12.

11.

In vivo adenoviral transfer of sorcin reverses cardiac contractile abnormalities of diabetic cardiomyopathy.

Suarez J, Belke DD, Gloss B, Dieterle T, McDonough PM, Kim YK, Brunton LL, Dillmann WH.

Am J Physiol Heart Circ Physiol. 2004 Jan;286(1):H68-75. Epub 2003 Sep 4.

12.

Angiotensin II enhances adenylyl cyclase signaling via Ca2+/calmodulin. Gq-Gs cross-talk regulates collagen production in cardiac fibroblasts.

Ostrom RS, Naugle JE, Hase M, Gregorian C, Swaney JS, Insel PA, Brunton LL, Meszaros JG.

J Biol Chem. 2003 Jul 4;278(27):24461-8. Epub 2003 Apr 23.

13.

Calcium signaling in excystation of the early diverging eukaryote, Giardia lamblia.

Reiner DS, Hetsko ML, Meszaros JG, Sun CH, Morrison HG, Brunton LL, Gillin FD.

J Biol Chem. 2003 Jan 24;278(4):2533-40. Epub 2002 Oct 22.

14.

Cyclic nucleotide research -- still expanding after half a century.

Beavo JA, Brunton LL.

Nat Rev Mol Cell Biol. 2002 Sep;3(9):710-8. doi: 10.1038/nrm911. Review.

PMID:
12209131
15.
16.

Cloning, expression, signaling mechanisms, and membrane targeting of P2Y(11) receptors in Madin Darby canine kidney cells.

Zambon AC, Brunton LL, Barrett KE, Hughes RJ, Torres B, Insel PA.

Mol Pharmacol. 2001 Jul;60(1):26-35.

17.

Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.

Steinberg SF, Brunton LL.

Annu Rev Pharmacol Toxicol. 2001;41:751-73. Review.

PMID:
11264475
18.

P2Y(2) receptor of MDCK cells: cloning, expression, and cell-specific signaling.

Zambon AC, Hughes RJ, Meszaros JG, Wu JJ, Torres B, Brunton LL, Insel PA.

Am J Physiol Renal Physiol. 2000 Dec;279(6):F1045-52.

20.

Protein kinase C contributes to desensitization of ANG II signaling in adult rat cardiac fibroblasts.

Meszaros JG, Raphael R, Lio FM, Brunton LL.

Am J Physiol Cell Physiol. 2000 Dec;279(6):C1978-85.

21.

Characterization of G-protein signaling in ventricular myocytes from the adult mouse heart: differences from the rat.

Hilal-Dandan R, Kanter JR, Brunton LL.

J Mol Cell Cardiol. 2000 Jul;32(7):1211-21.

PMID:
10860764
22.

Identification of G protein-coupled signaling pathways in cardiac fibroblasts: cross talk between G(q) and G(s).

Meszaros JG, Gonzalez AM, Endo-Mochizuki Y, Villegas S, Villarreal F, Brunton LL.

Am J Physiol Cell Physiol. 2000 Jan;278(1):C154-62.

23.
24.

Inhibition of protein kinases by balanol: specificity within the serine/threonine protein kinase subfamily.

Setyawan J, Koide K, Diller TC, Bunnage ME, Taylor SS, Nicolaou KC, Brunton LL.

Mol Pharmacol. 1999 Aug;56(2):370-6.

25.

Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase.

Narayana N, Diller TC, Koide K, Bunnage ME, Nicolaou KC, Brunton LL, Xuong NH, Ten Eyck LF, Taylor SS.

Biochemistry. 1999 Feb 23;38(8):2367-76.

PMID:
10029530
26.

Small heat shock proteins and protection against ischemic injury in cardiac myocytes.

Martin JL, Mestril R, Hilal-Dandan R, Brunton LL, Dillmann WH.

Circulation. 1997 Dec 16;96(12):4343-8.

27.

The quasi-irreversible nature of endothelin binding and G protein-linked signaling in cardiac myocytes.

Hilal-Dandan R, Villegas S, Gonzalez A, Brunton LL.

J Pharmacol Exp Ther. 1997 Apr;281(1):267-73.

28.

Endothelin ETA receptor regulates signaling and ANF gene expression via multiple G protein-linked pathways.

Hilal-Dandan R, Ramirez MT, Villegas S, Gonzalez A, Endo-Mochizuki Y, Brown JH, Brunton LL.

Am J Physiol. 1997 Jan;272(1 Pt 2):H130-7.

PMID:
9038931
29.

Separation of cyclic GMP and cyclic AMP.

Villegas S, Brunton LL.

Anal Biochem. 1996 Mar 1;235(1):102-3. No abstract available.

PMID:
8850553
30.
31.

Molecular design and biological activity of potent and selective protein kinase inhibitors related to balanol.

Koide K, Bunnage ME, Gomez Paloma L, Kanter JR, Taylor SS, Brunton LL, Nicolaou KC.

Chem Biol. 1995 Sep;2(9):601-8.

32.

Transmembrane mechanochemical coupling in cardiac myocytes: novel activation of Gi by hyposmotic swelling.

Hilal-Dandan R, Brunton LL.

Am J Physiol. 1995 Sep;269(3 Pt 2):H798-804.

PMID:
7573520
33.

Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes.

Pucéat M, Hilal-Dandan R, Strulovici B, Brunton LL, Brown JH.

J Biol Chem. 1994 Jun 17;269(24):16938-44.

34.

Coupling of the type A endothelin receptor to multiple responses in adult rat cardiac myocytes.

Hilal-Dandan R, Merck DT, Lujan JP, Brunton LL.

Mol Pharmacol. 1994 Jun;45(6):1183-90.

PMID:
8022411
35.

Received knowledge.

Brunton LL.

Nature. 1994 May 26;369(6478):270. No abstract available.

PMID:
8183359
36.

Endothelin inhibits adenylate cyclase and stimulates phosphoinositide hydrolysis in adult cardiac myocytes.

Hilal-Dandan R, Urasawa K, Brunton LL.

J Biol Chem. 1992 May 25;267(15):10620-4.

37.

A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

McMahan CJ, Slack JL, Mosley B, Cosman D, Lupton SD, Brunton LL, Grubin CE, Wignall JM, Jenkins NA, Brannan CI, et al.

EMBO J. 1991 Oct;10(10):2821-32.

38.

Differential effects of omega-3 fish oils on protein kinase activities in vitro.

Speizer LA, Watson MJ, Brunton LL.

Am J Physiol. 1991 Jul;261(1 Pt 1):E109-14.

PMID:
1858866
39.

Dominant positive and negative selection using a hygromycin phosphotransferase-thymidine kinase fusion gene.

Lupton SD, Brunton LL, Kalberg VA, Overell RW.

Mol Cell Biol. 1991 Jun;11(6):3374-8.

40.

Cellular distribution of phosphodiesterase isoforms in rat cardiac tissue.

Bode DC, Kanter JR, Brunton LL.

Circ Res. 1991 Apr;68(4):1070-9.

41.

Insulin stimulates the activity of a novel protein kinase C, PKC-epsilon, in cultured fetal chick neurons.

Heidenreich KA, Toledo SP, Brunton LL, Watson MJ, Daniel-Issakani S, Strulovici B.

J Biol Chem. 1990 Sep 5;265(25):15076-82.

43.

Characterization of the human and murine IL-7 genes.

Lupton SD, Gimpel S, Jerzy R, Brunton LL, Hjerrild KA, Cosman D, Goodwin RG.

J Immunol. 1990 May 1;144(9):3592-601.

PMID:
2329282
44.

Non-steady state kinetic analysis of the regulation of adenylate cyclase by GTP-binding proteins.

Bell JD, Biltonen RL, Brunton LL.

Mol Pharmacol. 1990 Apr;37(4):535-45.

PMID:
2109182
45.

An STS in the human IL7 gene located at 8q12-13.

Brunton LL, Lupton SD.

Nucleic Acids Res. 1990 Mar 11;18(5):1315. No abstract available. Erratum in: Nucleic Acids Res 1990 May 11;18(9):2852.

46.

Inhibition of phorbol ester binding and protein kinase C activity by heavy metals.

Speizer LA, Watson MJ, Kanter JR, Brunton LL.

J Biol Chem. 1989 Apr 5;264(10):5581-5.

47.

Inhibition of cyclic AMP efflux by insect pheromones and fatty acids.

Kanter JR, Hagey LR, Brunton LL.

FEBS Lett. 1989 Feb 13;244(1):149-53.

48.

Characterization of hormone-sensitive adenylate cyclase in rabbit gallbladder mucosa.

Mertens RB, Sherr HP, Mayer SE, Wheeler HO, Brunton LL.

Int J Biochem. 1989;21(1):109-16.

PMID:
2546833
49.

Post-receptor modulation of the effects of cyclic AMP in isolated cardiac myocytes.

Bode DC, Brunton LL.

Mol Cell Biochem. 1988 Jul-Aug;82(1-2):13-8.

PMID:
2847010
50.

Resolution of soluble rat cardiac phosphodiesterases by high performance liquid chromatography.

Bode DC, Kanter JR, Brunton LL.

Second Messengers Phosphoproteins. 1988-1989;12(5-6):235-40.

PMID:
2856111

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