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Items: 7


Establishment and 12-month progress of the New Zealand Motor Neurone Disease Registry.

Walker KL, Rodrigues MJ, Watson B, Reilly C, Scotter EL, Brunton H, Turnbull J, Roxburgh RH.

J Clin Neurosci. 2019 Feb;60:7-11. doi: 10.1016/j.jocn.2018.11.034. Epub 2018 Nov 22. Review.


Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure.

Smith MP, Rowling EJ, Miskolczi Z, Ferguson J, Spoerri L, Haass NK, Sloss O, McEntegart S, Arozarena I, von Kriegsheim A, Rodriguez J, Brunton H, Kmarashev J, Levesque MP, Dummer R, Frederick DT, Andrews MC, Cooper ZA, Flaherty KT, Wargo JA, Wellbrock C.

EMBO Mol Med. 2017 Aug;9(8):1011-1029. doi: 10.15252/emmm.201607156.


Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy.

Smith MP, Brunton H, Rowling EJ, Ferguson J, Arozarena I, Miskolczi Z, Lee JL, Girotti MR, Marais R, Levesque MP, Dummer R, Frederick DT, Flaherty KT, Cooper ZA, Wargo JA, Wellbrock C.

Cancer Cell. 2016 Mar 14;29(3):270-284. doi: 10.1016/j.ccell.2016.02.003.


The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα.

Smith MP, Sanchez-Laorden B, O'Brien K, Brunton H, Ferguson J, Young H, Dhomen N, Flaherty KT, Frederick DT, Cooper ZA, Wargo JA, Marais R, Wellbrock C.

Cancer Discov. 2014 Oct;4(10):1214-1229. doi: 10.1158/2159-8290.CD-13-1007.


Visualisation of γH2AX foci caused by heavy ion particle traversal; distinction between core track versus non-track damage.

Nakajima NI, Brunton H, Watanabe R, Shrikhande A, Hirayama R, Matsufuji N, Fujimori A, Murakami T, Okayasu R, Jeggo P, Shibata A.

PLoS One. 2013 Aug 14;8(8):e70107. doi: 10.1371/journal.pone.0070107. eCollection 2013.


Analysis of human syndromes with disordered chromatin reveals the impact of heterochromatin on the efficacy of ATM-dependent G2/M checkpoint arrest.

Brunton H, Goodarzi AA, Noon AT, Shrikhande A, Hansen RS, Jeggo PA, Shibata A.

Mol Cell Biol. 2011 Oct;31(19):4022-35. doi: 10.1128/MCB.05289-11. Epub 2011 Jul 26.


Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair.

Woodbine L, Brunton H, Goodarzi AA, Shibata A, Jeggo PA.

Nucleic Acids Res. 2011 Sep 1;39(16):6986-97. doi: 10.1093/nar/gkr331. Epub 2011 May 19.

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