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Items: 9

1.

RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.

Parisien JP, Lenoir JJ, Mandhana R, Rodriguez KR, Qian K, Bruns AM, Horvath CM.

EMBO Rep. 2018 Jun;19(6). pii: e45176. doi: 10.15252/embr.201745176. Epub 2018 Apr 16.

PMID:
29661858
2.

Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted antiviral functions of APOBEC3G.

Pollpeter D, Parsons M, Sobala AE, Coxhead S, Lang RD, Bruns AM, Papaioannou S, McDonnell JM, Apolonia L, Chowdhury JA, Horvath CM, Malim MH.

Nat Microbiol. 2018 Feb;3(2):220-233. doi: 10.1038/s41564-017-0063-9. Epub 2017 Nov 20.

3.

LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling.

Bruns AM, Horvath CM.

Cytokine. 2015 Aug;74(2):198-206. doi: 10.1016/j.cyto.2015.02.010. Epub 2015 Mar 18. Review.

4.

The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly.

Bruns AM, Leser GP, Lamb RA, Horvath CM.

Mol Cell. 2014 Sep 4;55(5):771-81. doi: 10.1016/j.molcel.2014.07.003. Epub 2014 Aug 7.

5.

Antiviral RNA recognition and assembly by RLR family innate immune sensors.

Bruns AM, Horvath CM.

Cytokine Growth Factor Rev. 2014 Oct;25(5):507-12. doi: 10.1016/j.cytogfr.2014.07.006. Epub 2014 Jul 15. Review.

6.

MDA5 and LGP2: accomplices and antagonists of antiviral signal transduction.

Rodriguez KR, Bruns AM, Horvath CM.

J Virol. 2014 Aug;88(15):8194-200. doi: 10.1128/JVI.00640-14. Epub 2014 May 21. Review.

7.

Radiation-induced loss of cell surface CD47 enhances immune-mediated clearance of human papillomavirus-positive cancer.

Vermeer DW, Spanos WC, Vermeer PD, Bruns AM, Lee KM, Lee JH.

Int J Cancer. 2013 Jul;133(1):120-9. doi: 10.1002/ijc.28015. Epub 2013 Feb 12.

8.

ATP hydrolysis enhances RNA recognition and antiviral signal transduction by the innate immune sensor, laboratory of genetics and physiology 2 (LGP2).

Bruns AM, Pollpeter D, Hadizadeh N, Myong S, Marko JF, Horvath CM.

J Biol Chem. 2013 Jan 11;288(2):938-46. doi: 10.1074/jbc.M112.424416. Epub 2012 Nov 26.

9.

Activation of RIG-I-like receptor signal transduction.

Bruns AM, Horvath CM.

Crit Rev Biochem Mol Biol. 2012 Mar-Apr;47(2):194-206. doi: 10.3109/10409238.2011.630974. Epub 2011 Nov 8. Review.

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