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Items: 1 to 50 of 672

1.

Does the Coexistence of Chronic Obstructive Pulmonary Disease and Atrial Fibrillation Affect Nox2 Activity and Urinary Isoprostanes Excretion?

Pastori D, Andreozzi P, Carnevale R, Bartimoccia S, Limaj S, Melandri S, Brunori M, Spallacci G, Violi F, Pignatelli P.

Antioxid Redox Signal. 2019 Jul 23. doi: 10.1089/ars.2019.7811. [Epub ahead of print]

PMID:
31250672
2.

Laryngopharyngeal Reflux Diagnosis in Obstructive Sleep Apnea Patients Using the Pepsin Salivary Test.

Iannella G, Vicini C, Polimeni A, Greco A, Gobbi R, Montevecchi F, De Vito A, Meccariello G, Cammaroto G, D'Agostino G, Pace A, Cascella R, Brunori M, Lo Iacono CAM, Pelucchi S, Magliulo G.

Int J Environ Res Public Health. 2019 Jun 10;16(11). pii: E2056. doi: 10.3390/ijerph16112056.

3.

Reversibility of alexithymia with effective treatment of moderate-to-severe psoriasis: longitudinal data from EPIDEPSO.

Sampogna F, Puig L, Spuls P, Girolomoni G, Radtke MA, Kirby B, Brunori M, Bergmans P, Smirnov P, Rundle J, Castiglia A, Lavie F, Paul C.

Br J Dermatol. 2019 Feb;180(2):397-403. doi: 10.1111/bjd.17259. Epub 2018 Nov 26.

PMID:
30269346
4.

A Carboxylate to Amide Substitution That Switches Protein Folds.

Gianni S, McCully ME, Malagrinò F, Bonetti D, De Simone A, Brunori M, Daggett V.

Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12795-12798. doi: 10.1002/anie.201807723. Epub 2018 Aug 28.

PMID:
30098087
5.

Folding Mechanism of the SH3 Domain from Grb2.

Troilo F, Bonetti D, Camilloni C, Toto A, Longhi S, Brunori M, Gianni S.

J Phys Chem B. 2018 Dec 13;122(49):11166-11173. doi: 10.1021/acs.jpcb.8b06320. Epub 2018 Aug 23.

6.

Difficult-to-treat OSAS: Combined continuous positive airway pressure (CPAP) and mandibular advancement devices (MADs) therapy. A case report.

Luzzi V, Brunori M, Terranova S, Di Paolo C, Ierardo G, Vozza I, Polimeni A.

Cranio. 2018 Jul 26:1-5. doi: 10.1080/08869634.2018.1496628. [Epub ahead of print]

PMID:
30048222
7.

Mechanism of Folding and Binding of the N-Terminal SH2 Domain from SHP2.

Bonetti D, Troilo F, Toto A, Travaglini-Allocatelli C, Brunori M, Gianni S.

J Phys Chem B. 2018 Dec 13;122(49):11108-11114. doi: 10.1021/acs.jpcb.8b05651. Epub 2018 Aug 7.

PMID:
30047735
8.

How Robust Is the Mechanism of Folding-Upon-Binding for an Intrinsically Disordered Protein?

Bonetti D, Troilo F, Brunori M, Longhi S, Gianni S.

Biophys J. 2018 Apr 24;114(8):1889-1894. doi: 10.1016/j.bpj.2018.03.017.

9.

Long-term prediction of adherence to continuous positive air pressure therapy for the treatment of moderate/severe obstructive sleep apnea syndrome.

Baratta F, Pastori D, Bucci T, Fabiani M, Fabiani V, Brunori M, Loffredo L, Lillo R, Pannitteri G, Angelico F, Del Ben M.

Sleep Med. 2018 Mar;43:66-70. doi: 10.1016/j.sleep.2017.09.032. Epub 2018 Feb 8.

PMID:
29482815
10.

Severity of OSAS, CPAP and cardiovascular events: A follow-up study.

Baratta F, Pastori D, Fabiani M, Fabiani V, Ceci F, Lillo R, Lolli V, Brunori M, Pannitteri G, Cravotto E, De Vito C, Angelico F, Del Ben M.

Eur J Clin Invest. 2018 May;48(5):e12908. doi: 10.1111/eci.12908. Epub 2018 Mar 3.

PMID:
29424037
11.

Identification of a novel nucleophosmin-interaction motif in the tumor suppressor p14arf.

Luchinat E, Chiarella S, Franceschini M, Di Matteo A, Brunori M, Banci L, Federici L.

FEBS J. 2018 Mar;285(5):832-847. doi: 10.1111/febs.14373. Epub 2018 Jan 15.

12.

Early decrease of oxidative stress by non-invasive ventilation in patients with acute respiratory failure.

Garramone A, Cangemi R, Bresciani E, Carnevale R, Bartimoccia S, Fante E, Corinti M, Brunori M, Violi F, Bertazzoni G, Pignatelli P.

Intern Emerg Med. 2018 Mar;13(2):183-190. doi: 10.1007/s11739-017-1750-5. Epub 2017 Sep 15.

PMID:
28914417
13.

Analyzing the Folding and Binding Steps of an Intrinsically Disordered Protein by Protein Engineering.

Bonetti D, Troilo F, Toto A, Brunori M, Longhi S, Gianni S.

Biochemistry. 2017 Jul 25;56(29):3780-3786. doi: 10.1021/acs.biochem.7b00350. Epub 2017 Jul 11.

PMID:
28661120
14.

The Folding Pathway of the KIX Domain.

Troilo F, Bonetti D, Toto A, Visconti L, Brunori M, Longhi S, Gianni S.

ACS Chem Biol. 2017 Jun 16;12(6):1683-1690. doi: 10.1021/acschembio.7b00289. Epub 2017 May 8.

PMID:
28459531
15.

Laparoscopic Sleeve Gastrectomy Changes in the Last Decade: Differences in Morbidity and Weight Loss.

Balla A, Quaresima S, Leonetti F, Paone E, Brunori M, Messina T, Seitaj A, Paganini AM.

J Laparoendosc Adv Surg Tech A. 2017 Nov;27(11):1165-1171. doi: 10.1089/lap.2017.0059. Epub 2017 Apr 21.

PMID:
28430045
16.

Active Surveillance Beyond 5 Years Is Required for Presumed Branch-Duct Intraductal Papillary Mucinous Neoplasms Undergoing Non-Operative Management.

Crippa S, Pezzilli R, Bissolati M, Capurso G, Romano L, Brunori MP, Calculli L, Tamburrino D, Piccioli A, Ruffo G, Fave GD, Falconi M.

Am J Gastroenterol. 2017 Jul;112(7):1153-1161. doi: 10.1038/ajg.2017.43. Epub 2017 Feb 28.

PMID:
28244498
17.

Prevalence of alexithymia in patients with psoriasis and its association with disease burden: a multicentre observational study.

Sampogna F, Puig L, Spuls P, Girolomoni G, Radtke MA, Kirby B, Brunori M, Bergmans P, Smirnov P, Rundle J, Lavie F, Paul C; EPIDEPSO Investigators.

Br J Dermatol. 2017 May;176(5):1195-1203. doi: 10.1111/bjd.15243. Epub 2017 Apr 10.

PMID:
27995617
18.

Neuroglobin: From structure to function in health and disease.

Ascenzi P, di Masi A, Leboffe L, Fiocchetti M, Nuzzo MT, Brunori M, Marino M.

Mol Aspects Med. 2016 Dec;52:1-48. doi: 10.1016/j.mam.2016.10.004. Epub 2016 Nov 4. Review.

PMID:
27825818
19.

Towards a structural biology of the hydrophobic effect in protein folding.

Camilloni C, Bonetti D, Morrone A, Giri R, Dobson CM, Brunori M, Gianni S, Vendruscolo M.

Sci Rep. 2016 Jul 27;6:28285. doi: 10.1038/srep28285.

20.

Molecular medicine - To be or not to be.

Brunori M, Gianni S.

Biophys Chem. 2016 Jul-Aug;214-215:33-46. doi: 10.1016/j.bpc.2016.05.004. Epub 2016 May 13. Review.

PMID:
27214761
21.

Identification and Structural Characterization of an Intermediate in the Folding of the Measles Virus X Domain.

Bonetti D, Camilloni C, Visconti L, Longhi S, Brunori M, Vendruscolo M, Gianni S.

J Biol Chem. 2016 May 13;291(20):10886-92. doi: 10.1074/jbc.M116.721126. Epub 2016 Mar 21.

22.

Molecular Recognition by Templated Folding of an Intrinsically Disordered Protein.

Toto A, Camilloni C, Giri R, Brunori M, Vendruscolo M, Gianni S.

Sci Rep. 2016 Feb 25;6:21994. doi: 10.1038/srep21994.

23.

Frustration Sculpts the Early Stages of Protein Folding.

Di Silvio E, Brunori M, Gianni S.

Angew Chem Int Ed Engl. 2015 Sep 7;54(37):10867-9. doi: 10.1002/anie.201504835. Epub 2015 Jul 23.

PMID:
26212018
24.

Half a Century of Hemoglobin's Allostery.

Brunori M.

Biophys J. 2015 Sep 15;109(6):1077-9. doi: 10.1016/j.bpj.2015.06.025. Epub 2015 Jul 16. No abstract available.

25.

Health and social impacts of COPD and the problem of under-diagnosis.

Carlone S, Balbi B, Bezzi M, Brunori M, Calabro S, Foschino Barbaro MP, Micheletto C, Privitera S, Torchio R, Schino P, Vianello A.

Multidiscip Respir Med. 2014 Dec 6;9(1):63. doi: 10.1186/2049-6958-9-63. eCollection 2014. Review.

26.

Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein.

Gianni S, Camilloni C, Giri R, Toto A, Bonetti D, Morrone A, Sormanni P, Brunori M, Vendruscolo M.

Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):14141-6. doi: 10.1073/pnas.1405233111. Epub 2014 Sep 16.

27.

Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism.

Avella G, Ardiccioni C, Scaglione A, Moschetti T, Rondinelli C, Montemiglio LC, Savino C, Giuffrè A, Brunori M, Vallone B.

Acta Crystallogr D Biol Crystallogr. 2014 Jun;70(Pt 6):1640-8. doi: 10.1107/S1399004714007032. Epub 2014 May 29.

PMID:
24914975
28.

The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb.

Toto A, Giri R, Brunori M, Gianni S.

Protein Sci. 2014 Jul;23(7):962-9. doi: 10.1002/pro.2480. Epub 2014 May 9.

29.

The kinetics of folding of frataxin.

Bonetti D, Toto A, Giri R, Morrone A, Sanfelice D, Pastore A, Temussi P, Gianni S, Brunori M.

Phys Chem Chem Phys. 2014 Apr 14;16(14):6391-7. doi: 10.1039/c3cp54055c. Epub 2014 Jan 15.

PMID:
24429875
30.

Efficacy and tolerability of bendamustine, bortezomib and dexamethasone in patients with relapsed-refractory multiple myeloma: a phase II study.

Offidani M, Corvatta L, Maracci L, Liberati AM, Ballanti S, Attolico I, Caraffa P, Alesiani F, Caravita di Toritto T, Gentili S, Tosi P, Brunori M, Derudas D, Ledda A, Gozzetti A, Cellini C, Malerba L, Mele A, Andriani A, Galimberti S, Mondello P, Pulini S, Coppetelli U, Fraticelli P, Olivieri A, Leoni P.

Blood Cancer J. 2013 Nov 22;3:e162. doi: 10.1038/bcj.2013.58.

31.

Variations on the theme: allosteric control in hemoglobin.

Brunori M.

FEBS J. 2014 Jan;281(2):633-43. doi: 10.1111/febs.12586. Epub 2013 Nov 28. Review.

32.

One-year safety and efficacy of ustekinumab and results of dose adjustment after switching from inadequate methotrexate treatment: the TRANSIT randomized trial in moderate-to-severe plaque psoriasis.

Reich K, Puig L, Paul C, Kragballe K, Luger T, Lambert J, Chimenti S, Girolomoni G, Nicolas JF, Rizova E, Brunori M, Mistry S, Bergmans P, Barker J; TRANSIT Investigators.

Br J Dermatol. 2014 Feb;170(2):435-44. doi: 10.1111/bjd.12643.

PMID:
24116868
33.

Switching between the alternative structures and functions of a 2-Cys peroxiredoxin, by site-directed mutagenesis.

Angelucci F, Saccoccia F, Ardini M, Boumis G, Brunori M, Di Leandro L, Ippoliti R, Miele AE, Natoli G, Scotti S, Bellelli A.

J Mol Biol. 2013 Nov 15;425(22):4556-68. doi: 10.1016/j.jmb.2013.09.002. Epub 2013 Sep 8.

PMID:
24021815
34.

Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system.

Giri R, Morrone A, Toto A, Brunori M, Gianni S.

Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14942-7. doi: 10.1073/pnas.1307337110. Epub 2013 Aug 26.

35.

The mitochondrial Italian Human Proteome Project initiative (mt-HPP).

Urbani A, De Canio M, Palmieri F, Sechi S, Bini L, Castagnola M, Fasano M, Modesti A, Roncada P, Timperio AM, Bonizzi L, Brunori M, Cutruzzolà F, De Pinto V, Di Ilio C, Federici G, Folli F, Foti S, Gelfi C, Lauro D, Lucacchini A, Magni F, Messana I, Pandolfi PP, Papa S, Pucci P, Sacchetta P; Italian Mt-Hpp Study Group-Italian Proteomics Association (www.itpa.it).

Mol Biosyst. 2013 Aug;9(8):1984-92. doi: 10.1039/c3mb70065h. Epub 2013 May 28.

PMID:
23712443
36.

The folding pathway of a functionally competent C-terminal domain of nucleophosmin: protein stability and denatured state residual structure.

Chiarella S, Federici L, Di Matteo A, Brunori M, Gianni S.

Biochem Biophys Res Commun. 2013 May 24;435(1):64-8. doi: 10.1016/j.bbrc.2013.04.038. Epub 2013 Apr 22.

PMID:
23618861
37.

Hemoglobin allostery: new views on old players.

Miele AE, Bellelli A, Brunori M.

J Mol Biol. 2013 May 13;425(9):1515-26. doi: 10.1016/j.jmb.2012.12.018. Epub 2012 Dec 28.

PMID:
23274140
38.

A folding-after-binding mechanism describes the recognition between the transactivation domain of c-Myb and the KIX domain of the CREB-binding protein.

Gianni S, Morrone A, Giri R, Brunori M.

Biochem Biophys Res Commun. 2012 Nov 16;428(2):205-9. doi: 10.1016/j.bbrc.2012.09.112. Epub 2012 Sep 28.

PMID:
23026051
39.

Reassessing the folding of the KIX domain: evidence for a two-state mechanism.

Morrone A, Giri R, Brunori M, Gianni S.

Protein Sci. 2012 Nov;21(11):1775-9. doi: 10.1002/pro.2159. Epub 2012 Oct 9.

40.

The Bohr effect before Perutz.

Brunori M.

Biochem Mol Biol Educ. 2012 Sep-Oct;40(5):297-9. doi: 10.1002/bmb.20629. Epub 2012 Aug 1.

41.

Assessment of vulnerability measures and their effect on survival in a real-life population of multiple myeloma patients registered at Marche Region Multiple Myeloma Registry.

Offidani M, Corvatta L, Polloni C, Centurioni R, Visani G, Brunori M, Gentili S, Catarini M, Samori A, Blasi N, Alesiani F, Caraffa P, Burattini M, Galieni P, Fraticelli P, Ferranti M, Giuliodori L, Leoni P.

Clin Lymphoma Myeloma Leuk. 2012 Dec;12(6):423-32. doi: 10.1016/j.clml.2012.06.008. Epub 2012 Sep 14.

PMID:
22981966
42.

The Monod-Wyman-Changeux allosteric model accounts for the quaternary transition dynamics in wild type and a recombinant mutant human hemoglobin.

Levantino M, Spilotros A, Cammarata M, Schirò G, Ardiccioni C, Vallone B, Brunori M, Cupane A.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14894-9. doi: 10.1073/pnas.1205809109. Epub 2012 Aug 27.

43.

Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target.

Boumis G, Giardina G, Angelucci F, Bellelli A, Brunori M, Dimastrogiovanni D, Saccoccia F, Miele AE.

Biochem Biophys Res Commun. 2012 Sep 7;425(4):806-11. doi: 10.1016/j.bbrc.2012.07.156. Epub 2012 Aug 6.

PMID:
22889878
44.

Oxidative stress mediated arterial dysfunction in patients with obstructive sleep apnoea and the effect of continuous positive airway pressure treatment.

Del Ben M, Fabiani M, Loffredo L, Polimeni L, Carnevale R, Baratta F, Brunori M, Albanese F, Augelletti T, Violi F, Angelico F.

BMC Pulm Med. 2012 Jul 23;12:36. doi: 10.1186/1471-2466-12-36.

45.

Structure of nucleophosmin DNA-binding domain and analysis of its complex with a G-quadruplex sequence from the c-MYC promoter.

Gallo A, Lo Sterzo C, Mori M, Di Matteo A, Bertini I, Banci L, Brunori M, Federici L.

J Biol Chem. 2012 Aug 3;287(32):26539-48. doi: 10.1074/jbc.M112.371013. Epub 2012 Jun 15.

46.

Folding pathways of proteins with increasing degree of sequence identities but different structure and function.

Giri R, Morrone A, Travaglini-Allocatelli C, Jemth P, Brunori M, Gianni S.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17772-6. doi: 10.1073/pnas.1201794109. Epub 2012 May 31.

47.

Tailored therapy in an unselected population of 91 elderly patients with DLBCL prospectively evaluated using a simplified CGA.

Olivieri A, Gini G, Bocci C, Montanari M, Trappolini S, Olivieri J, Brunori M, Catarini M, Guiducci B, Isidori A, Alesiani F, Giuliodori L, Marcellini M, Visani G, Poloni A, Leoni P.

Oncologist. 2012;17(5):663-72. doi: 10.1634/theoncologist.2011-0355. Epub 2012 Apr 24.

48.

Morphogenesis of a protein: folding pathways and the energy landscape.

Brunori M, Gianni S, Giri R, Morrone A, Travaglini-Allocatelli C.

Biochem Soc Trans. 2012 Apr;40(2):429-32. doi: 10.1042/BST20110683. Review.

PMID:
22435825
49.

Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin.

Saccoccia F, Di Micco P, Boumis G, Brunori M, Koutris I, Miele AE, Morea V, Sriratana P, Williams DL, Bellelli A, Angelucci F.

Structure. 2012 Mar 7;20(3):429-39. doi: 10.1016/j.str.2012.01.004.

50.

On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases.

Saccoccia F, Angelucci F, Boumis G, Brunori M, Miele AE, Williams DL, Bellelli A.

J Inorg Biochem. 2012 Mar;108:105-11. doi: 10.1016/j.jinorgbio.2011.11.005. Epub 2011 Nov 27.

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