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Items: 1 to 50 of 143

1.

aYAP modRNA reduces cardiac inflammation and hypertrophy in a murine ischemia-reperfusion model.

Chen J, Ma Q, King JS, Sun Y, Xu B, Zhang X, Zohrabian S, Guo H, Cai W, Li G, Bruno I, Cooke JP, Wang C, Kontaridis M, Wang DZ, Luo H, Pu WT, Lin Z.

Life Sci Alliance. 2019 Dec 16;3(1). pii: e201900424. doi: 10.26508/lsa.201900424. Print 2020 Jan.

2.

Effects of Some Food Components on Non-Alcoholic Fatty Liver Disease Severity: Results from a Cross-Sectional Study.

Mirizzi A, Franco I, Leone CM, Bonfiglio C, Cozzolongo R, Notarnicola M, Giannuzzi V, Tutino V, De Nunzio V, Bruno I, Buongiorno C, Campanella A, Deflorio V, Pascale A, Procino F, Sorino P, Osella AR.

Nutrients. 2019 Nov 12;11(11). pii: E2744. doi: 10.3390/nu11112744.

3.

Intranasal dexmedetomidine and intravenous ketamine for procedural sedation in a child with alpha-mannosidosis: a magic bullet?

Trevisan M, Romano S, Barbi E, Bruno I, Murru FM, Cozzi G.

Ital J Pediatr. 2019 Sep 3;45(1):119. doi: 10.1186/s13052-019-0711-1.

4.

When fingers point to the diagnosis.

Trombetta A, Magnolato A, Bruno I, Rabach I, Murru FM, Faletra F.

Arch Dis Child. 2019 Aug 10. pii: archdischild-2019-317514. doi: 10.1136/archdischild-2019-317514. [Epub ahead of print] No abstract available.

PMID:
31401559
5.

Massive Coronary Microvascular Dysfunction in Severe Anderson-Fabry Disease Cardiomyopathy.

Graziani F, Lillo R, Panaioli E, Spagnoletti G, Bruno I, Leccisotti L, Marano R, Manna R, Crea F.

Circ Cardiovasc Imaging. 2019 Jun;12(6):e009104. doi: 10.1161/CIRCIMAGING.119.009104. Epub 2019 Jun 10. No abstract available.

PMID:
31177818
6.

Transient introduction of human telomerase mRNA improves hallmarks of progeria cells.

Li Y, Zhou G, Bruno IG, Zhang N, Sho S, Tedone E, Lai TP, Cooke JP, Shay JW.

Aging Cell. 2019 Aug;18(4):e12979. doi: 10.1111/acel.12979. Epub 2019 May 31.

7.

Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition.

Giordano A, Forte G, Terracciano S, Russo A, Sala M, Scala MC, Johansson C, Oppermann U, Riccio R, Bruno I, Di Micco S.

ACS Med Chem Lett. 2019 Feb 25;10(4):601-605. doi: 10.1021/acsmedchemlett.8b00589. eCollection 2019 Apr 11.

PMID:
30996803
8.

Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic Syndrome.

Giampietro L, Laghezza A, Cerchia C, Florio R, Recinella L, Capone F, Ammazzalorso A, Bruno I, De Filippis B, Fantacuzzi M, Ferrante C, Maccallini C, Tortorella P, Verginelli F, Brunetti L, Cama A, Amoroso R, Loiodice F, Lavecchia A.

ACS Med Chem Lett. 2019 Feb 25;10(4):545-551. doi: 10.1021/acsmedchemlett.8b00574. eCollection 2019 Apr 11.

PMID:
30996794
9.

Could a chimeric condition be responsible for unexpected genetic syndromes? The role of the single nucleotide polymorphism-array analysis.

Bottega R, Cappellani S, Fabretto A, Spinelli AM, Severini GM, Aloisio M, Faleschini M, Athanasakis E, Bruno I, Faletra F, Pecile V.

Mol Genet Genomic Med. 2019 Mar;7(3):e546. doi: 10.1002/mgg3.546. Epub 2019 Jan 9.

10.

Parathyroid scintigraphy in primary hyperparathyroidism: comparison between double-phase and subtraction techniques and possible affecting factors.

Maccora D, Rizzo V, Fortini D, Mariani M, Giraldi L, Giordano A, Bruno I.

J Endocrinol Invest. 2019 Aug;42(8):889-895. doi: 10.1007/s40618-018-0996-8. Epub 2019 Jan 1.

PMID:
30600433
11.

Next Generation Molecular Diagnosis of Hereditary Spastic Paraplegias: An Italian Cross-Sectional Study.

D'Amore A, Tessa A, Casali C, Dotti MT, Filla A, Silvestri G, Antenora A, Astrea G, Barghigiani M, Battini R, Battisti C, Bruno I, Cereda C, Dato C, Di Iorio G, Donadio V, Felicori M, Fini N, Fiorillo C, Gallone S, Gemignani F, Gigli GL, Graziano C, Guerrini R, Gurrieri F, Kariminejad A, Lieto M, Marques LourenḈo C, Malandrini A, Mandich P, Marcotulli C, Mari F, Massacesi L, Melone MAB, Mignarri A, Milone R, Musumeci O, Pegoraro E, Perna A, Petrucci A, Pini A, Pochiero F, Pons MR, Ricca I, Rossi S, Seri M, Stanzial F, Tinelli F, Toscano A, Valente M, Federico A, Rubegni A, Santorelli FM.

Front Neurol. 2018 Dec 4;9:981. doi: 10.3389/fneur.2018.00981. eCollection 2018.

12.

When Long-Lasting Food Selectivity Leads to an Unusual Genetic Diagnosis: A Case Report.

Da Lozzo P, Magnolato A, Del Rizzo I, Sirchia F, Bruno I, Barbi E.

J Adolesc Health. 2019 Jan;64(1):137-138. doi: 10.1016/j.jadohealth.2018.07.014. Epub 2018 Oct 14.

PMID:
30327278
13.

Reducing NAFLD-screening time: A comparative study of eight diagnostic methods offering an alternative to ultrasound scans.

Procino F, Misciagna G, Veronese N, Caruso MG, Chiloiro M, Cisternino AM, Notarnicola M, Bonfiglio C, Bruno I, Buongiorno C, Campanella A, Deflorio V, Franco I, Guerra R, Leone CM, Mirizzi A, Nitti A, Osella AR; MICOL GROUP.

Liver Int. 2019 Jan;39(1):187-196. doi: 10.1111/liv.13970. Epub 2018 Oct 22.

PMID:
30248233
14.

Innovation for rare diseases and bioethical concerns: A thin thread between medical progress and suffering.

Tommasini A, Magnolato A, Bruno I.

World J Clin Pediatr. 2018 Aug 30;7(3):75-82. doi: 10.5409/wjcp.v7.i3.75. eCollection 2018 Aug 30.

15.

Tuning the biomimetic performances of 4-hydroxyproline-containing cyclic peptoids.

Schettini R, Costabile C, Della Sala G, Buirey J, Tosolini M, Tecilla P, Vaccaro MC, Bruno I, De Riccardis F, Izzo I.

Org Biomol Chem. 2018 Sep 19;16(36):6708-6717. doi: 10.1039/c8ob01522h.

PMID:
30182115
16.

Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells.

Khalfaoui A, Chini MG, Bouheroum M, Belaabed S, Lauro G, Terracciano S, Vaccaro MC, Bruno I, Benayache S, Mancini I, Bifulco G.

J Nat Prod. 2018 Aug 24;81(8):1786-1794. doi: 10.1021/acs.jnatprod.8b00234. Epub 2018 Jul 31.

PMID:
30063349
17.

Irisin Serum Levels in Metabolic Syndrome Patients Treated with Three Different Diets: A Post-Hoc Analysis from a Randomized Controlled Clinical Trial.

Osella AR, Colaianni G, Correale M, Pesole PL, Bruno I, Buongiorno C, Deflorio V, Leone CM, Colucci SC, Grano M, Giannelli G.

Nutrients. 2018 Jun 28;10(7). pii: E844. doi: 10.3390/nu10070844.

18.

Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors.

Di Micco S, Pulvirenti L, Bruno I, Terracciano S, Russo A, Vaccaro MC, Ruggiero D, Muccilli V, Cardullo N, Tringali C, Riccio R, Bifulco G.

Bioorg Med Chem. 2018 Aug 7;26(14):3953-3957. doi: 10.1016/j.bmc.2018.06.019. Epub 2018 Jun 20.

PMID:
29934219
19.

Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics.

Terracciano S, Lauro G, Russo A, Vaccaro MC, Vassallo A, De Marco M, Ranieri B, Rosati A, Turco MC, Riccio R, Bifulco G, Bruno I.

Chem Commun (Camb). 2018 Jul 5;54(55):7613-7616. doi: 10.1039/c8cc03399d.

PMID:
29926854
20.

[Kawasaki disease shock syndrome: a case report].

Vieni G, Pusceddu S, Bruno I, Ragni L, Marchetti F.

G Ital Cardiol (Rome). 2018 Feb;19(2):111-114. doi: 10.1714/2868.28942. Italian.

PMID:
29531383
21.

[Prevention of medication errors during intravenous drug administration in intensive care units: a literature review.]

Di Simone E, Giannetta N, Spada E, Bruno I, Dionisi S, Chiarini M, Tartaglini D, Di Muzio M.

Recenti Prog Med. 2018 Feb;109(2):103-107. doi: 10.1701/2865.28902. Review. Italian.

PMID:
29493633
22.

Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain.

Terracciano S, Russo A, Chini MG, Vaccaro MC, Potenza M, Vassallo A, Riccio R, Bifulco G, Bruno I.

Sci Rep. 2018 Jan 26;8(1):1709. doi: 10.1038/s41598-017-14902-y.

23.

Discovery of new potent molecular entities able to inhibit mPGES-1.

Di Micco S, Terracciano S, Cantone V, Fischer K, Koeberle A, Foglia A, Riccio R, Werz O, Bruno I, Bifulco G.

Eur J Med Chem. 2018 Jan 1;143:1419-1427. doi: 10.1016/j.ejmech.2017.10.039. Epub 2017 Oct 23.

PMID:
29133047
24.

Telomerase mRNA Reverses Senescence in Progeria Cells.

Li Y, Zhou G, Bruno IG, Cooke JP.

J Am Coll Cardiol. 2017 Aug 8;70(6):804-805. doi: 10.1016/j.jacc.2017.06.017. No abstract available.

25.

Cyclic Peptoids as Mycotoxin Mimics: An Exploration of Their Structural and Biological Properties.

D'Amato A, Volpe R, Vaccaro MC, Terracciano S, Bruno I, Tosolini M, Tedesco C, Pierri G, Tecilla P, Costabile C, Della Sala G, Izzo I, De Riccardis F.

J Org Chem. 2017 Sep 1;82(17):8848-8863. doi: 10.1021/acs.joc.7b00965. Epub 2017 Aug 17.

PMID:
28763612
26.

Cytotoxic effect of a family of peroxisome proliferator-activated receptor antagonists in colorectal and pancreatic cancer cell lines.

Ammazzalorso A, De Lellis L, Florio R, Bruno I, De Filippis B, Fantacuzzi M, Giampietro L, Maccallini C, Perconti S, Verginelli F, Cama A, Amoroso R.

Chem Biol Drug Des. 2017 Nov;90(5):1029-1035. doi: 10.1111/cbdd.13026. Epub 2017 Jul 19.

PMID:
28544586
27.

[Asteroid hyalopathy (benson's disease): about a case].

Bienvenu YA, Angel MN, Leon KN, Socrate KM, Bruno IOK, Gaby CB.

Pan Afr Med J. 2017 Jan 31;26:47. doi: 10.11604/pamj.2017.26.47.8601. eCollection 2017. French.

28.

Histoproteomic Characterization of Localized Cutaneous Amyloidosis in X-Linked Reticulate Pigmentary Disorder.

L'Imperio V, Bruno I, Rabach I, Smith A, Chinello C, Stella M, Magni F, Pagni F.

Skin Pharmacol Physiol. 2017;30(2):90-93. doi: 10.1159/000464336. Epub 2017 Apr 4. No abstract available.

29.

Independent Relationship of Osteocalcin Circulating Levels with Obesity, Type 2 Diabetes, Hypertension, and HDL Cholesterol.

De Pergola G, Triggiani V, Bartolomeo N, Nardecchia A, Giagulli VA, Bruno I, Caccavo D, Silvestris F.

Endocr Metab Immune Disord Drug Targets. 2016;16(4):270-275. doi: 10.2174/1871530317666170106150756.

PMID:
28059033
30.

Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors.

Terracciano S, Chini MG, Vaccaro MC, Strocchia M, Foglia A, Vassallo A, Saturnino C, Riccio R, Bifulco G, Bruno I.

Chem Commun (Camb). 2016 Nov 10;52(92):13515.

PMID:
27805204
31.

Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors.

Terracciano S, Chini MG, Vaccaro MC, Strocchia M, Foglia A, Vassallo A, Saturnino C, Riccio R, Bifulco G, Bruno I.

Chem Commun (Camb). 2016 Oct 25;52(87):12857-12860. Erratum in: Chem Commun (Camb). 2016 Nov 10;52(92):13515. Teracciano S [corrected to Terracciano S].

PMID:
27731433
32.

Macrocephaly and palmoplantar pitting.

Rabach I, Salis S, Bruno I, Ventura A.

Arch Dis Child. 2016 Oct;101(10):973. doi: 10.1136/archdischild-2016-310771. Epub 2016 Jun 28. No abstract available.

PMID:
27355975
33.

The Cambridge Structural Database.

Groom CR, Bruno IJ, Lightfoot MP, Ward SC.

Acta Crystallogr B Struct Sci Cryst Eng Mater. 2016 Apr;72(Pt 2):171-9. doi: 10.1107/S2052520616003954. Epub 2016 Apr 1.

34.

Synthesis, in vitro evaluation, and molecular modeling investigation of benzenesulfonimide peroxisome proliferator-activated receptors α antagonists.

Ammazzalorso A, Carrieri A, Verginelli F, Bruno I, Carbonara G, D'Angelo A, De Filippis B, Fantacuzzi M, Florio R, Fracchiolla G, Giampietro L, Giancristofaro A, Maccallini C, Cama A, Amoroso R.

Eur J Med Chem. 2016 May 23;114:191-200. doi: 10.1016/j.ejmech.2016.02.064. Epub 2016 Feb 27.

PMID:
26974385
35.

Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme.

Lauro G, Tortorella P, Bertamino A, Ostacolo C, Koeberle A, Fischer K, Bruno I, Terracciano S, Gomez-Monterrey IM, Tauro M, Loiodice F, Novellino E, Riccio R, Werz O, Campiglia P, Bifulco G.

ChemMedChem. 2016 Mar 17;11(6):612-9. doi: 10.1002/cmdc.201500598. Epub 2016 Feb 24.

PMID:
26915684
36.

The value of imaging in subclinical coronary artery disease.

Zimarino M, Prati F, Marano R, Angeramo F, Pescetelli I, Gatto L, Marco V, Bruno I, De Caterina R.

Vascul Pharmacol. 2016 Jul;82:20-9. doi: 10.1016/j.vph.2016.02.001. Epub 2016 Feb 4. Review.

PMID:
26851577
37.

Screening of NOS activity and selectivity of newly synthesized acetamidines using RP-HPLC.

Fantacuzzi M, Maccallini C, Di Matteo M, Ammazzalorso A, Bruno I, De Filippis B, Giampietro L, Mollica A, Amoroso R.

J Pharm Biomed Anal. 2016 Feb 20;120:419-24. doi: 10.1016/j.jpba.2015.11.045. Epub 2015 Dec 2.

PMID:
26689740
38.

Synthesis of Naphthyl-, Quinolin- and Anthracenyl Analogues of Clofibric Acid as PPARα Agonists.

Giampietro L, Ammazzalorso A, Bruno I, Carradori S, De Filippis B, Fantacuzzi M, Giancristofaro A, Maccallini C, Amoroso R.

Chem Biol Drug Des. 2016 Mar;87(3):467-71. doi: 10.1111/cbdd.12677. Epub 2015 Nov 20.

PMID:
26502898
39.

Legius syndrome: case report and review of literature.

Benelli E, Bruno I, Belcaro C, Ventura A, Berti I.

Ital J Pediatr. 2015 Feb 8;41:8. doi: 10.1186/s13052-015-0115-9. Review.

40.

9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain.

Picaud S, Strocchia M, Terracciano S, Lauro G, Mendez J, Daniels DL, Riccio R, Bifulco G, Bruno I, Filippakopoulos P.

J Med Chem. 2015 Mar 26;58(6):2718-36. doi: 10.1021/jm501893k. Epub 2015 Mar 5.

41.

Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors.

Terracciano S, Lauro G, Strocchia M, Fischer K, Werz O, Riccio R, Bruno I, Bifulco G.

ACS Med Chem Lett. 2015 Jan 7;6(2):187-91. doi: 10.1021/ml500433j. eCollection 2015 Feb 12.

42.

Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold.

Strocchia M, Terracciano S, Chini MG, Vassallo A, Vaccaro MC, Dal Piaz F, Leone A, Riccio R, Bruno I, Bifulco G.

Chem Commun (Camb). 2015 Mar 4;51(18):3850-3. doi: 10.1039/c4cc10074c.

PMID:
25656927
43.

A brain and heart connection: X-linked periventricular heterotopia.

Naviglio S, Bruno I, Zanus C, Faletra F, Ventura A.

J Pediatr. 2015 Mar;166(3):776. doi: 10.1016/j.jpeds.2014.11.037. Epub 2014 Dec 31. No abstract available.

PMID:
25557968
44.

[Atypical ocular toxoplasmosis in a Congolese woman of 72 years: report of a case].

Bienvenu YA, Angel MN, Eric KI, Socrate KM, Sebastien MM, Philippe CM, Leon KN, Bruno IO, Gaby CB.

Pan Afr Med J. 2015 Nov 20;22:267. doi: 10.11604/pamj.2015.22.267.8137. eCollection 2015. French. No abstract available.

45.

"Blaschkoid dyspigmentation" in a child: don't forget fibroblast chromosomal analysis.

Gortani G, Faletra F, Bruno I, Berti I, Ventura A.

J Pediatr. 2015 Feb;166(2):490-90.e1. doi: 10.1016/j.jpeds.2014.10.028. Epub 2014 Nov 27. No abstract available.

PMID:
25433905
46.

High yield recovery of equine mesenchymal stem cells from umbilical cord matrix/Wharton's jelly using a semi-automated process.

Nazari-Shafti TZ, Bruno IG, Martinez RF, Coleman ME, Alt EU, McClure SR.

Methods Mol Biol. 2015;1235:131-46. doi: 10.1007/978-1-4939-1785-3_12.

PMID:
25388392
47.

A crystallographic perspective on sharing data and knowledge.

Bruno IJ, Groom CR.

J Comput Aided Mol Des. 2014 Oct;28(10):1015-22. doi: 10.1007/s10822-014-9780-9. Epub 2014 Aug 5.

48.

Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E₂ synthase-1 enzyme (mPGES-1).

Lauro G, Strocchia M, Terracciano S, Bruno I, Fischer K, Pergola C, Werz O, Riccio R, Bifulco G.

Eur J Med Chem. 2014 Jun 10;80:407-15. doi: 10.1016/j.ejmech.2014.04.061. Epub 2014 Apr 24.

PMID:
24794772
49.

Possible direct influence of complement 3 in decreasing insulin sensitvity in a cohort of overweight and obese subjects.

De Pergola G, Tartagni M, Bartolomeo N, Bruno I, Masiello M, Caccavo D, Bavaro S, Silvestris F.

Endocr Metab Immune Disord Drug Targets. 2013 Dec;13(4):301-5.

PMID:
24428680
50.

Autosomal recessive Stickler syndrome due to a loss of function mutation in the COL9A3 gene.

Faletra F, D'Adamo AP, Bruno I, Athanasakis E, Biskup S, Esposito L, Gasparini P.

Am J Med Genet A. 2014 Jan;164A(1):42-7. doi: 10.1002/ajmg.a.36165. Epub 2013 Nov 22.

PMID:
24273071

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