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Isocitrate dehydrogenase 1 and 2 mutations, 2-hydroxyglutarate levels, and response to standard chemotherapy for patients with newly diagnosed acute myeloid leukemia.

Brunner AM, Neuberg DS, Wander SA, Sadrzadeh H, Ballen KK, Amrein PC, Attar E, Hobbs GS, Chen YB, Perry A, Connolly C, Joseph C, Burke M, Ramos A, Galinsky I, Yen K, Yang H, Straley K, Agresta S, Adamia S, Borger DR, Iafrate A, Graubert TA, Stone RM, Fathi AT.

Cancer. 2018 Nov 13. doi: 10.1002/cncr.31729. [Epub ahead of print]


Online parallel accumulation - serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer.

Meier F, Brunner AD, Koch S, Koch H, Lubeck M, Krause M, Goedecke N, Decker J, Kosinski T, Park MA, Bache N, Hoerning O, Cox J, Räther O, Mann M.

Mol Cell Proteomics. 2018 Nov 1. pii: mcp.TIR118.000900. doi: 10.1074/mcp.TIR118.000900. [Epub ahead of print]


Prioritizing anthropogenic chemicals in drinking water and sources through combined use of mass spectrometry and ToxCast toxicity data.

Brunner AM, Dingemans MML, Baken KA, van Wezel AP.

J Hazard Mater. 2018 Oct 18;364:332-338. doi: 10.1016/j.jhazmat.2018.10.044. [Epub ahead of print]


Screw tip augmentation leads to improved primary stability in the minimally invasive treatment of displaced intra-articular fractures of the calcaneus: a biomechanical study.

Eichinger M, Brunner A, Stofferin H, Bölderl A, Blauth M, Schmölz W.

Int Orthop. 2018 Oct 10. doi: 10.1007/s00264-018-4171-9. [Epub ahead of print]


Monitoring transformation product formation in the drinking water treatments rapid sand filtration and ozonation.

Brunner AM, Vughs D, Siegers W, Bertelkamp C, Hofman-Caris R, Kolkman A, Ter Laak T.

Chemosphere. 2019 Jan;214:801-811. doi: 10.1016/j.chemosphere.2018.09.140. Epub 2018 Sep 26.


Results of universal ultrasound screening for developmental dysplasia of the hip.

Biedermann R, Riccabona J, Giesinger JM, Brunner A, Liebensteiner M, Wansch J, Dammerer D, Nogler M.

Bone Joint J. 2018 Oct;100-B(10):1399-1404. doi: 10.1302/0301-620X.100B10.BJJ-2017-1539.R2.


Clustered incidence of adult acute promyelocytic leukemia.

Brunner AM, Kim PG, Sadrzadeh H, Drapkin BJ, Sprague KA, Sloan JM, Chai-Ho W, Bhargava P, Pozdnyakova O, Fathi AT.

Leuk Res. 2018 Nov;74:47-50. doi: 10.1016/j.leukres.2018.09.008. Epub 2018 Sep 19. No abstract available.


Low Clinical Trial Accrual of Patients With Myelodysplastic Syndromes: Causes and Potential Solutions.

Steensma DP, Brunner AM, DeZern AE, Garcia-Manero G, Komrokji RS, Odenike OS, Roboz GJ, Savona MR, Stone RM, Sekeres MA.

Cancer. 2018 Oct 5. doi: 10.1002/cncr.31769. [Epub ahead of print]


Clinical infrared microscopic imaging: An overview.

Pallua JD, Brunner A, Zelger B, Stalder R, Unterberger SH, Schirmer M, Tappert MC.

Pathol Res Pract. 2018 Oct;214(10):1532-1538. doi: 10.1016/j.prp.2018.08.026. Epub 2018 Sep 4. Review.


Characteristics and predictors for secondary leukemia and myelodysplastic syndrome in Ewing and osteosarcoma survivors.

Sanford NN, Miao R, Wang H, Goldberg S, Jacobson A, Brunner AM, Cote GM, Yock TI, Ebb DH, Chen YB, Jee KW, Hornicek F, DeLaney TF, Choy E, Chen YL.

Int J Radiat Oncol Biol Phys. 2018 Aug 27. pii: S0360-3016(18)33643-5. doi: 10.1016/j.ijrobp.2018.08.037. [Epub ahead of print]


Patient-Clinician Discordance in Perceptions of Treatment Risks and Benefits in Older Patients with Acute Myeloid Leukemia.

El-Jawahri A, Nelson-Lowe M, VanDusen H, Traeger L, Abel GA, Greer JA, Fathi A, Steensma DP, LeBlanc TW, Li Z, DeAngelo D, Wadleigh M, Hobbs G, Foster J, Brunner A, Amrein P, Stone RM, Temel JS.

Oncologist. 2018 Aug 23. pii: theoncologist.2018-0317. doi: 10.1634/theoncologist.2018-0317. [Epub ahead of print]


Phenotypic Expression and Stability in a Large-Scale Field Study of Genetically Engineered Poplars Containing Sexual Containment Transgenes.

Klocko AL, Lu H, Magnuson A, Brunner AM, Ma C, Strauss SH.

Front Bioeng Biotechnol. 2018 Aug 3;6:100. doi: 10.3389/fbioe.2018.00100. eCollection 2018.


The use of immunosuppressive therapy in MDS: clinical outcomes and their predictors in a large international patient cohort.

Stahl M, DeVeaux M, de Witte T, Neukirchen J, Sekeres MA, Brunner AM, Roboz GJ, Steensma DP, Bhatt VR, Platzbecker U, Cluzeau T, Prata PH, Itzykson R, Fenaux P, Fathi AT, Smith A, Germing U, Ritchie EK, Verma V, Nazha A, Maciejewski JP, Podoltsev NA, Prebet T, Santini V, Gore SD, Komrokji RS, Zeidan AM.

Blood Adv. 2018 Jul 24;2(14):1765-1772. doi: 10.1182/bloodadvances.2018019414.


Impact of lenalidomide use among non-transfusion dependent patients with myelodysplastic syndromes.

Brunner AM, Weng S, Cronin A, Fathi AT, Habib AR, Stone R, Graubert T, Steensma DP, Abel GA.

Am J Hematol. 2018 Sep;93(9):1119-1126. doi: 10.1002/ajh.25166. Epub 2018 Aug 28.


Repurposing an Old Drug for a New Epidemic: Ursodeoxycholic Acid to Prevent Recurrent Clostridioides difficile Infection.

Webb BJ, Brunner A, Lewis J, Ford CD, Lopansri B.

Clin Infect Dis. 2018 Jul 18. doi: 10.1093/cid/ciy568. [Epub ahead of print]


Performance of the Medical Research Council (MRC) and the Leukemia Research Foundation (LRF) score in predicting survival benefit with hypomethylating agent use in patients with relapsed or refractory acute myeloid leukemia.

Stahl M, DeVeaux M, Montesinos P, Itzykson R, Ritchie EK, Sekeres MA, Barnard J, Podoltsev NA, Brunner A, Komrokji RS, Bhatt VR, Al-Kali A, Cluzeau T, Santini V, Roboz GJ, Fenaux P, Litzow M, Fathi AT, Perreault S, Kim TK, Prebet T, Vey N, Verma V, Germing U, Bergua J, Serrano J, Gore SD, Zeidan AM.

Leuk Lymphoma. 2018 Jul 2:1-4. doi: 10.1080/10428194.2018.1468893. [Epub ahead of print] No abstract available.


Prognostic Value of Testing PD-L1 Expression After Radical Cystectomy in High-risk Patients.

Pichler R, Fritz J, Lackner F, Sprung S, Brunner A, Horninger W, Loidl W, Pircher A, Heidegger I.

Clin Genitourin Cancer. 2018 Oct;16(5):e1015-e1024. doi: 10.1016/j.clgc.2018.05.015. Epub 2018 Jun 8.


Reformulating acute myeloid leukemia: liposomal cytarabine and daunorubicin (CPX-351) as an emerging therapy for secondary AML.

Chen EC, Fathi AT, Brunner AM.

Onco Targets Ther. 2018 Jun 12;11:3425-3434. doi: 10.2147/OTT.S141212. eCollection 2018. Review.


Incident adverse events following therapy for acute promyelocytic leukemia.

Kim PG, Bridgham K, Chen EC, Vidula MK, Pozdnyakova O, Brunner AM, Fathi AT.

Leuk Res Rep. 2018 May 5;9:79-83. doi: 10.1016/j.lrr.2018.05.001. eCollection 2018.


Outcomes and predictors of survival in blast phase myeloproliferative neoplasms.

Lancman G, Brunner A, Hoffman R, Mascarenhas J, Hobbs G.

Leuk Res. 2018 May 21;70:49-55. doi: 10.1016/j.leukres.2018.05.004. [Epub ahead of print]


High NPM1-mutant allele burden at diagnosis predicts unfavorable outcomes in de novo AML.

Patel SS, Kuo FC, Gibson CJ, Steensma DP, Soiffer RJ, Alyea EP 3rd, Chen YA, Fathi AT, Graubert TA, Brunner AM, Wadleigh M, Stone RM, DeAngelo DJ, Nardi V, Hasserjian RP, Weinberg OK.

Blood. 2018 Jun 21;131(25):2816-2825. doi: 10.1182/blood-2018-01-828467. Epub 2018 May 3.


Hypomethylating agents in relapsed and refractory AML: outcomes and their predictors in a large international patient cohort.

Stahl M, DeVeaux M, Montesinos P, Itzykson R, Ritchie EK, Sekeres MA, Barnard JD, Podoltsev NA, Brunner AM, Komrokji RS, Bhatt VR, Al-Kali A, Cluzeau T, Santini V, Fathi AT, Roboz GJ, Fenaux P, Litzow MR, Perreault S, Kim TK, Prebet T, Vey N, Verma V, Germing U, Bergua JM, Serrano J, Gore SD, Zeidan AM.

Blood Adv. 2018 Apr 24;2(8):923-932. doi: 10.1182/bloodadvances.2018016121.


Allogeneic Hematopoietic Stem Cell Transplantation Following the Use of Hypomethylating Agents among Patients with Relapsed or Refractory AML: Findings from an International Retrospective Study.

Stahl M, DeVeaux M, Montesinos P, Itzykson R, Ritchie EK, Sekeres MA, Majhail N, Barnard J, Podoltsev NA, Brunner AM, Komrokji RS, Bhatt VR, Al-Kali A, Cluzeau T, Santini V, Roboz GJ, Fenaux P, Litzow M, Fathi AT, Perreault S, Kim TK, Prebet T, Vey N, Verma V, Kobbe G, Bergua J, Serrano J, Gore SD, Zeidan AM.

Biol Blood Marrow Transplant. 2018 Aug;24(8):1754-1758. doi: 10.1016/j.bbmt.2018.03.025. Epub 2018 Apr 9.


High IDO-1 expression in tumor endothelial cells is associated with response to immunotherapy in metastatic renal cell carcinoma.

Seeber A, Klinglmair G, Fritz J, Steinkohl F, Zimmer KC, Aigner F, Horninger W, Gastl G, Zelger B, Brunner A, Pichler R.

Cancer Sci. 2018 May;109(5):1583-1591. doi: 10.1111/cas.13560. Epub 2018 Apr 16.


No Mutation Left Behind: The Impact of Reporting Recurrent Genetic Abnormalities on Outcomes of Patients with Acute Myeloid Leukemia.

Brunner AM.

Acta Haematol. 2018;139(2):128-130. doi: 10.1159/000487071. Epub 2018 Feb 14. No abstract available.


Secondary Acute Leukemia in Sarcoma Patients: A Population-Based Study.

Sanford NN, Martin AM, Brunner AM, Cote GM, Choy E, DeLaney TF, Aizer AA, Chen YL.

Int J Radiat Oncol Biol Phys. 2018 Mar 1;100(3):687-694. doi: 10.1016/j.ijrobp.2017.11.011. Epub 2017 Nov 14.


Prevalence of Cam and Pincer Deformities in the X-Rays of Asymptomatic Individuals.

Thier S, Gerisch D, Weiss C, Fickert S, Brunner A.

Biomed Res Int. 2017;2017:8562329. doi: 10.1155/2017/8562329. Epub 2017 Dec 18.


DIVARICATA AND RADIALIS INTERACTING FACTOR (DRIF) also interacts with WOX and KNOX proteins associated with wood formation in Populus trichocarpa.

Petzold HE, Chanda B, Zhao C, Rigoulot SB, Beers EP, Brunner AM.

Plant J. 2018 Mar;93(6):1076-1087. doi: 10.1111/tpj.13831. Epub 2018 Feb 23.


Benefit of 18F-fluorocholine PET imaging in parathyroid surgery.

Huber GF, Hüllner M, Schmid C, Brunner A, Sah B, Vetter D, Kaufmann PA, von Schulthess GK.

Eur Radiol. 2018 Jun;28(6):2700-2707. doi: 10.1007/s00330-017-5190-4. Epub 2018 Jan 25.


Genomics in childhood acute myeloid leukemia comes of age.

Brunner AM, Graubert TA.

Nat Med. 2018 Jan 9;24(1):7-9. doi: 10.1038/nm.4469. No abstract available.


Risk and timing of cardiovascular death among patients with myelodysplastic syndromes.

Brunner AM, Blonquist TM, Hobbs GS, Amrein PC, Neuberg DS, Steensma DP, Abel GA, Fathi AT.

Blood Adv. 2017 Oct 18;1(23):2032-2040. doi: 10.1182/bloodadvances.2017010165. eCollection 2017 Oct 24.


Implementation and Evaluation of an Economic Model for Telestroke: Experience from Virtuall, France.

Riou-Comte N, Mione G, Humbertjean L, Brunner A, Vezain A, Lavandier K, Marchal S, Bracard S, Debouverie M, Richard S.

Front Neurol. 2017 Nov 20;8:613. doi: 10.3389/fneur.2017.00613. eCollection 2017.


Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling.

Sassi Y, Avramopoulos P, Ramanujam D, Grüter L, Werfel S, Giosele S, Brunner AD, Esfandyari D, Papadopoulou AS, De Strooper B, Hübner N, Kumarswamy R, Thum T, Yin X, Mayr M, Laggerbauer B, Engelhardt S.

Nat Commun. 2017 Nov 20;8(1):1614. doi: 10.1038/s41467-017-01737-4.


Cognitive reappraisal and acceptance: Effects on emotion, physiology, and perceived cognitive costs.

Troy AS, Shallcross AJ, Brunner A, Friedman R, Jones MC.

Emotion. 2018 Feb;18(1):58-74. doi: 10.1037/emo0000371. Epub 2017 Nov 20.


RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations.

Fischer MM, Yeung VP, Cattaruzza F, Hussein R, Yen WC, Murriel C, Evans JW, O'Young G, Brunner AL, Wang M, Cain J, Cancilla B, Kapoun A, Hoey T.

Sci Rep. 2017 Nov 10;7(1):15270. doi: 10.1038/s41598-017-15704-y.


A phase I study of lenalidomide plus chemotherapy with mitoxantrone, etoposide, and cytarabine for the reinduction of patients with acute myeloid leukemia.

DeAngelo DJ, Brunner AM, Werner L, Avigan D, Fathi AT, Sperling AS, Washington A, Stroopinsky D, Rosenblatt J, McMasters M, Luptakova K, Wadleigh M, Steensma DP, Hobbs GS, Attar EC, Amrein PC, Ebert BL, Stone RM, Ballen KK.

Am J Hematol. 2018 Feb;93(2):254-261. doi: 10.1002/ajh.24968. Epub 2017 Nov 21.


Identification of new protein-protein and protein-DNA interactions linked with wood formation in Populus trichocarpa.

Petzold HE, Rigoulot SB, Zhao C, Chanda B, Sheng X, Zhao M, Jia X, Dickerman AW, Beers EP, Brunner AM.

Tree Physiol. 2018 Mar 1;38(3):362-377. doi: 10.1093/treephys/tpx121.


PD-L1 expression in bladder cancer and metastasis and its influence on oncologic outcome after cystectomy.

Pichler R, Heidegger I, Fritz J, Danzl M, Sprung S, Zelger B, Brunner A, Pircher A.

Oncotarget. 2017 Aug 3;8(40):66849-66864. doi: 10.18632/oncotarget.19913. eCollection 2017 Sep 15.


Isolated radial neck delayed union/nonunion after conservative treatment in adults: two case reports and a literature review.

Babst C, Brunner A, Babst R.

Arch Orthop Trauma Surg. 2018 Feb;138(2):179-188. doi: 10.1007/s00402-017-2805-9. Epub 2017 Oct 3.


Cabozantinib is well tolerated in acute myeloid leukemia and effectively inhibits the resistance-conferring FLT3/tyrosine kinase domain/F691 mutation.

Fathi AT, Blonquist TM, Hernandez D, Amrein PC, Ballen KK, McMasters M, Avigan DE, Joyce R, Logan EK, Hobbs G, Brunner AM, Joseph C, Perry AM, Burke M, Behnan T, Foster J, Bergeron MK, Moran JA, Ramos AY, Som TT, Rae J, Fishman KM, McGregor KL, Connolly C, Neuberg DS, Levis MJ.

Cancer. 2018 Jan 15;124(2):306-314. doi: 10.1002/cncr.31038. Epub 2017 Sep 28. Erratum in: Cancer. 2018 May 15;124(10 ):2258.


Acute Leukemia is Associated with Cardiac Alterations before Chemotherapy.

Assuncao BMBL, Handschumacher MD, Brunner AM, Yucel E, Bartko PE, Cheng KH, Campos O, Fathi AT, Tan TC, Scherrer-Crosbie M.

J Am Soc Echocardiogr. 2017 Nov;30(11):1111-1118. doi: 10.1016/j.echo.2017.07.016. Epub 2017 Sep 15.


Insect Bite Hypersensitivity in Horses is Associated with Airway Hyperreactivity.

Lanz S, Brunner A, Graubner C, Marti E, Gerber V.

J Vet Intern Med. 2017 Nov;31(6):1877-1883. doi: 10.1111/jvim.14817. Epub 2017 Sep 18.


Development and Validation of a Novel Acute Myeloid Leukemia-Composite Model to Estimate Risks of Mortality.

Sorror ML, Storer BE, Fathi AT, Gerds AT, Medeiros BC, Shami P, Brunner AM, Sekeres MA, Mukherjee S, Peña E, Elsawy M, Wardyn S, Whitten J, Moore R, Becker PS, McCune JS, Appelbaum FR, Estey EH.

JAMA Oncol. 2017 Dec 1;3(12):1675-1682. doi: 10.1001/jamaoncol.2017.2714.


High-dose Thiotepa, Busulfan, Cyclophosphamide, and Autologous Stem Cell Transplantation as Upfront Consolidation for Systemic Non-Hodgkin Lymphoma With Synchronous Central Nervous System Involvement.

Qualls D, Sullivan A, Li S, Brunner AM, Collier K, Hochberg E, Armand P, Batchelor TT, Chen YB, DeFilipp Z.

Clin Lymphoma Myeloma Leuk. 2017 Dec;17(12):884-888. doi: 10.1016/j.clml.2017.08.100. Epub 2017 Aug 15.


Early infectious complications among patients treated with induction compared to hypomethylating therapy for acute myeloid leukemia.

Jalbut MM, Brunner AM, Amrein PC, Ballen KK, Hobbs GS, Perry AM, Joseph CP, Fathi AT.

Leuk Lymphoma. 2018 Apr;59(4):988-991. doi: 10.1080/10428194.2017.1361028. Epub 2017 Aug 9. No abstract available.


XYLEM NAC DOMAIN1, an angiosperm NAC transcription factor, inhibits xylem differentiation through conserved motifs that interact with RETINOBLASTOMA-RELATED.

Zhao C, Lasses T, Bako L, Kong D, Zhao B, Chanda B, Bombarely A, Cruz-Ramírez A, Scheres B, Brunner AM, Beers EP.

New Phytol. 2017 Oct;216(1):76-89. doi: 10.1111/nph.14704. Epub 2017 Jul 25.


Acceptance of Ambulatory Laparoscopic Cholecystectomy in Central Switzerland.

Widjaja SP, Fischer H, Brunner AR, Honigmann P, Metzger J.

World J Surg. 2017 Nov;41(11):2731-2734. doi: 10.1007/s00268-017-4098-0.


Association between insurance status at diagnosis and overall survival in chronic myeloid leukemia: A population-based study.

Perry AM, Brunner AM, Zou T, McGregor KL, Amrein PC, Hobbs GS, Ballen KK, Neuberg DS, Fathi AT.

Cancer. 2017 Jul 1;123(13):2561-2569. doi: 10.1002/cncr.30639. Epub 2017 May 2.


A versatile method for dynamically controlled patterning of small populations of epithelial cells on substrates via non-contact piezoelectric inkjet printing.

Lee KB, Kelbauskas L, Brunner A, Meldrum DR.

PLoS One. 2017 Apr 26;12(4):e0176079. doi: 10.1371/journal.pone.0176079. eCollection 2017.

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