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Items: 4

1.

The human Shu complex functions with PDS5B and SPIDR to promote homologous recombination.

Martino J, Brunette GJ, Barroso-González J, Moiseeva TN, Smith CM, Bakkenist CJ, O'Sullivan RJ, Bernstein KA.

Nucleic Acids Res. 2019 Nov 4;47(19):10151-10165. doi: 10.1093/nar/gkz738.

2.

Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells.

Garcin EB, Gon S, Sullivan MR, Brunette GJ, Cian A, Concordet JP, Giovannangeli C, Dirks WG, Eberth S, Bernstein KA, Prakash R, Jasin M, Modesti M.

PLoS Genet. 2019 Oct 4;15(10):e1008355. doi: 10.1371/journal.pgen.1008355. eCollection 2019 Oct.

3.

Evolution-based screening enables genome-wide prioritization and discovery of DNA repair genes.

Brunette GJ, Jamalruddin MA, Baldock RA, Clark NL, Bernstein KA.

Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19593-19599. doi: 10.1073/pnas.1906559116. Epub 2019 Sep 9.

PMID:
31501324
4.

Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma.

Kondrashova O, Nguyen M, Shield-Artin K, Tinker AV, Teng NNH, Harrell MI, Kuiper MJ, Ho GY, Barker H, Jasin M, Prakash R, Kass EM, Sullivan MR, Brunette GJ, Bernstein KA, Coleman RL, Floquet A, Friedlander M, Kichenadasse G, O'Malley DM, Oza A, Sun J, Robillard L, Maloney L, Bowtell D, Giordano H, Wakefield MJ, Kaufmann SH, Simmons AD, Harding TC, Raponi M, McNeish IA, Swisher EM, Lin KK, Scott CL; AOCS Study Group.

Cancer Discov. 2017 Sep;7(9):984-998. doi: 10.1158/2159-8290.CD-17-0419. Epub 2017 Jun 6.

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