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Items: 27


Low temperature traps myosin motors of mammalian muscle in a refractory state that prevents activation.

Caremani M, Brunello E, Linari M, Fusi L, Irving TC, Gore D, Piazzesi G, Irving M, Lombardi V, Reconditi M.

J Gen Physiol. 2019 Sep 25. pii: jgp.201912424. doi: 10.1085/jgp.201912424. [Epub ahead of print]


Thick Filament Length Changes in Muscle Have Both Elastic and Structural Components.

Reconditi M, Fusi L, Caremani M, Brunello E, Linari M, Piazzesi G, Lombardi V, Irving M.

Biophys J. 2019 Mar 19;116(6):983-984. doi: 10.1016/j.bpj.2019.02.009. Epub 2019 Mar 2. No abstract available.


Thick filament mechano-sensing is a calcium-independent regulatory mechanism in skeletal muscle.

Fusi L, Brunello E, Yan Z, Irving M.

Nat Commun. 2016 Oct 31;7:13281. doi: 10.1038/ncomms13281.


Minimum number of myosin motors accounting for shortening velocity under zero load in skeletal muscle.

Fusi L, Percario V, Brunello E, Caremani M, Bianco P, Powers JD, Reconditi M, Lombardi V, Piazzesi G.

J Physiol. 2017 Feb 15;595(4):1127-1142. doi: 10.1113/JP273299. Epub 2016 Dec 12.


Italian recommendations on dental support in the treatment of adult obstructive sleep apnea syndrome (OSAS).

Levrini L, Sacchi F, Milano F, Polimeni A, Cozza P, Bernkopf E, Segù M; Italian dentist work group about OSAS Collaborators, Zucconi M, Vicini C, Brunello E.

Ann Stomatol (Roma). 2016 Feb 12;6(3-4):81-6. doi: 10.11138/ads/2015.6.3.081. eCollection 2015 Jul-Dec. Review.


Force generation by skeletal muscle is controlled by mechanosensing in myosin filaments.

Linari M, Brunello E, Reconditi M, Fusi L, Caremani M, Narayanan T, Piazzesi G, Lombardi V, Irving M.

Nature. 2015 Dec 10;528(7581):276-9. doi: 10.1038/nature15727. Epub 2015 Nov 11.


Monosomy of chromosome 17 in breast cancer during interpretation of HER2 gene amplification.

Brunelli M, Nottegar A, Bogina G, Caliò A, Cima L, Eccher A, Vicentini C, Marcolini L, Scarpa A, Pedron S, Brunello E, Knuutila S, Sapino A, Marchiò C, Bria E, Molino A, Carbognin L, Tortora G, Jasani B, Miller K, Merdol I, Zanatta L, Laurino L, Wirtanen T, Zamboni G, Marconi M, Chilosi M, Manfrin E, Martignoni G, Bonetti F.

Am J Cancer Res. 2015 Jun 15;5(7):2212-21. eCollection 2015.


The contributions of filaments and cross-bridges to sarcomere compliance in skeletal muscle.

Brunello E, Caremani M, Melli L, Linari M, Fernandez-Martinez M, Narayanan T, Irving M, Piazzesi G, Lombardi V, Reconditi M.

J Physiol. 2014 Sep 1;592(17):3881-99. doi: 10.1113/jphysiol.2014.276196. Epub 2014 Jul 11.


The myofilament elasticity and its effect on kinetics of force generation by the myosin motor.

Piazzesi G, Dolfi M, Brunello E, Fusi L, Reconditi M, Bianco P, Linari M, Lombardi V.

Arch Biochem Biophys. 2014 Jun 15;552-553:108-16. doi: 10.1016/ Epub 2014 Mar 12.


Structural dynamics of troponin during activation of skeletal muscle.

Fusi L, Brunello E, Sevrieva IR, Sun YB, Irving M.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4626-31. doi: 10.1073/pnas.1321868111. Epub 2014 Mar 10.


Sarcomere-length dependence of myosin filament structure in skeletal muscle fibres of the frog.

Reconditi M, Brunello E, Fusi L, Linari M, Martinez MF, Lombardi V, Irving M, Piazzesi G.

J Physiol. 2014 Mar 1;592(5):1119-37. doi: 10.1113/jphysiol.2013.267849. Epub 2013 Dec 16.


The non-linear elasticity of the muscle sarcomere and the compliance of myosin motors.

Fusi L, Brunello E, Reconditi M, Piazzesi G, Lombardi V.

J Physiol. 2014 Mar 1;592(5):1109-18. doi: 10.1113/jphysiol.2013.265983. Epub 2013 Dec 16.


HER2/neu gene determination in women screened for breast carcinoma: how screening programs reduce the skyrocketing cost of targeted therapy.

Brunelli M, Manfrin E, Bria E, Massari F, Tortora G, Brunello E, Carbognin L, Nottegar A, Furlanetto J, Molino A, Fiorio E, Chilosi M, Jasani B, Vergine M, Marcolini L, Filippini D, Scarpa A, Martignoni G, Bonetti F; Members of Veneto Region - Pathology Screening Group.

Anticancer Res. 2013 Sep;33(9):3705-10.


The identification of a small but significant subset of patients still targetable with anti-HER2 inhibitors when affected by triple negative breast carcinoma.

Brunello E, Bogina G, Bria E, Vergine M, Zamboni G, Pedron S, Daniele I, Furlanetto J, Carbognin L, Marconi M, Manfrin E, Ibrahim M, Miller K, Tortora G, Molino A, Jasani B, Beccari S, Bonetti F, Chilosi M, Martignoni G, Brunelli M.

J Cancer Res Clin Oncol. 2013 Sep;139(9):1563-8. doi: 10.1007/s00432-013-1479-0. Epub 2013 Jul 28.


FGFR-1 amplification in metastatic lymph-nodal and haematogenous lobular breast carcinoma.

Brunello E, Brunelli M, Bogina G, Caliò A, Manfrin E, Nottegar A, Vergine M, Molino A, Bria E, Massari F, Tortora G, Cingarlini S, Pedron S, Chilosi M, Zamboni G, Miller K, Martignoni G, Bonetti F.

J Exp Clin Cancer Res. 2012 Dec 27;31:103. doi: 10.1186/1756-9966-31-103.


Mechanics of myosin function in white muscle fibres of the dogfish, Scyliorhinus canicula.

Park-Holohan S, Linari M, Reconditi M, Fusi L, Brunello E, Irving M, Dolfi M, Lombardi V, West TG, Curtin NA, Woledge RC, Piazzesi G.

J Physiol. 2012 Apr 15;590(8):1973-88. doi: 10.1113/jphysiol.2011.217133. Epub 2012 Feb 6.


Classical lobular breast carcinoma consistently lacks topoisomerase-IIα gene amplification: implications for the tailored use of anthracycline-based chemotherapies.

Brunello E, Brunelli M, Manfrin E, Nottegar A, Bersani S, Vergine M, Molino A, Fiorio E, Chilosi M, Gobbo S, Martignoni G, Bonetti F.

Histopathology. 2012 Feb;60(3):482-8. doi: 10.1111/j.1365-2559.2011.04067.x. Epub 2011 Dec 14.


Motion of myosin head domains during activation and force development in skeletal muscle.

Reconditi M, Brunello E, Linari M, Bianco P, Narayanan T, Panine P, Piazzesi G, Lombardi V, Irving M.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7236-40. doi: 10.1073/pnas.1018330108. Epub 2011 Apr 11.


Suitability of infiltrative lobular breast carcinoma for anti-human epidermal growth factor receptor 2 treatment after the ASCO/CAP and 2009 St Gallen International Expert Consensus meeting.

Vergine M, Brunelli M, Martignoni G, Brunello E, Miller K, Pecori S, Bersani S, Chilosi M, Menestrina F, Manfrin E, Bonetti F.

Histopathology. 2010 Dec;57(6):935-40. doi: 10.1111/j.1365-2559.2010.03716.x. No abstract available.


The mechanism of the resistance to stretch of isometrically contracting single muscle fibres.

Fusi L, Reconditi M, Linari M, Brunello E, Elangovan R, Lombardi V, Piazzesi G.

J Physiol. 2010 Feb 1;588(Pt 3):495-510. doi: 10.1113/jphysiol.2009.178137. Epub 2009 Nov 30.


Nebulin plays a direct role in promoting strong actin-myosin interactions.

Bang ML, Caremani M, Brunello E, Littlefield R, Lieber RL, Chen J, Lombardi V, Linari M.

FASEB J. 2009 Dec;23(12):4117-25. doi: 10.1096/fj.09-137729. Epub 2009 Aug 13.


Structural changes in myosin motors and filaments during relaxation of skeletal muscle.

Brunello E, Fusi L, Reconditi M, Linari M, Bianco P, Panine P, Narayanan T, Piazzesi G, Lombardi V, Irving M.

J Physiol. 2009 Sep 15;587(Pt 18):4509-21. doi: 10.1113/jphysiol.2009.176222. Epub 2009 Aug 3.


Nonneoplastic mimickers of pancreatic neoplasms.

Zamboni G, Capelli P, Scarpa A, Bogina G, Pesci A, Brunello E, Klöppel G.

Arch Pathol Lab Med. 2009 Mar;133(3):439-53. doi: 10.1043/1543-2165-133.3.439. Review.


Skeletal muscle resists stretch by rapid binding of the second motor domain of myosin to actin.

Brunello E, Reconditi M, Elangovan R, Linari M, Sun YB, Narayanan T, Panine P, Piazzesi G, Irving M, Lombardi V.

Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20114-9. Epub 2007 Dec 6.


Skeletal muscle performance determined by modulation of number of myosin motors rather than motor force or stroke size.

Piazzesi G, Reconditi M, Linari M, Lucii L, Bianco P, Brunello E, Decostre V, Stewart A, Gore DB, Irving TC, Irving M, Lombardi V.

Cell. 2007 Nov 16;131(4):784-95.


Structural changes in the myosin filament and cross-bridges during active force development in single intact frog muscle fibres: stiffness and X-ray diffraction measurements.

Brunello E, Bianco P, Piazzesi G, Linari M, Reconditi M, Panine P, Narayanan T, Helsby WI, Irving M, Lombardi V.

J Physiol. 2006 Dec 15;577(Pt 3):971-84. Epub 2006 Sep 21.


The structural basis of the increase in isometric force production with temperature in frog skeletal muscle.

Linari M, Brunello E, Reconditi M, Sun YB, Panine P, Narayanan T, Piazzesi G, Lombardi V, Irving M.

J Physiol. 2005 Sep 1;567(Pt 2):459-69. Epub 2005 Jun 16.

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