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Items: 1 to 50 of 309

1.

Herpes Simplex Virus Type 1 infection is associated with suicidal behavior and first registered psychiatric diagnosis in a healthy population.

Nissen J, Trabjerg B, Pedersen MG, Banasik K, Pedersen OB, Sørensen E, Nielsen KR, Erikstrup C, Petersen MS, Paarup HM, Bruun-Rasmussen P, Westergaard D, Hansen TF, Pedersen CB, Werge T, Torrey F, Hjalgrim H, Mortensen PB, Yolken R, Brunak S, Ullum H, Burgdorf KS.

Psychoneuroendocrinology. 2019 Jun 28;108:150-154. doi: 10.1016/j.psyneuen.2019.06.015. [Epub ahead of print]

2.

High-throughput sequencing-based investigation of viruses in human cancers by multi-enrichment approach.

Mollerup S, Asplund M, Friis-Nielsen J, Kjartansdóttir KR, Fridholm H, Hansen TA, Herrera JAR, Barnes CJ, Jensen RH, Richter SR, Nielsen IB, Pietroni C, Alquezar-Planas DE, Rey-Iglesia A, Olsen PVS, De Meyts ER, Groth-Pedersen L, von Buchwald C, Jensen DH, Gniadecki R, Høgdall E, Langhoff JL, Pete I, Vereczkey I, Baranyai Z, Dybkaer K, Johnsen HE, Steiniche T, Hokland P, Rosenberg J, Baandrup U, Sicheritz-Pontén T, Willerslev E, Brunak S, Lund O, Mourier T, Vinner L, Izarzugaza JMG, Nielsen LP, Hansen AJ.

J Infect Dis. 2019 Jun 28. pii: jiz318. doi: 10.1093/infdis/jiz318. [Epub ahead of print]

PMID:
31253993
3.

Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq.

Gådin JR, Buil A, Colantuoni C, Jaffe AE, Nielsen J, Shin JH, Hyde TM, Kleinman JE; BrainSeq Consortium, Plath N, Eriksson P, Brunak S, Didriksen M, Weinberger DR, Folkersen L.

PLoS One. 2019 Jun 17;14(6):e0217765. doi: 10.1371/journal.pone.0217765. eCollection 2019.

4.

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium.

Koivula RW, Forgie IM, Kurbasic A, Viñuela A, Heggie A, Giordano GN, Hansen TH, Hudson M, Koopman ADM, Rutters F, Siloaho M, Allin KH, Brage S, Brorsson CA, Dawed AY, De Masi F, Groves CJ, Kokkola T, Mahajan A, Perry MH, Rauh SP, Ridderstråle M, Teare HJA, Thomas EL, Tura A, Vestergaard H, White T, Adamski J, Bell JD, Beulens JW, Brunak S, Dermitzakis ET, Froguel P, Frost G, Gupta R, Hansen T, Hattersley A, Jablonka B, Kaye J, Laakso M, McDonald TJ, Pedersen O, Schwenk JM, Pavo I, Mari A, McCarthy MI, Ruetten H, Walker M, Pearson E, Franks PW; IMI DIRECT Consortium.

Diabetologia. 2019 Jun 15. doi: 10.1007/s00125-019-4906-1. [Epub ahead of print]

PMID:
31203377
5.

DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors.

Hansen TF, Banasik K, Erikstrup C, Pedersen OB, Westergaard D, Chmura PJ, Nielsen K, Thørner L, Hjalgrim H, Paarup H, Larsen MAH, Petersen M, Jennum P, Andersen S, Nyegaard M, Jemec GBE, Olesen J, Werge T, Johansson PI, Sørensen E, Brunak S, Ullum H, Burgdorf KS.

BMJ Open. 2019 Jun 9;9(6):e028401. doi: 10.1136/bmjopen-2018-028401.

6.

A Brief History of Protein Sorting Prediction.

Nielsen H, Tsirigos KD, Brunak S, von Heijne G.

Protein J. 2019 Jun;38(3):200-216. doi: 10.1007/s10930-019-09838-3. Review.

7.

Contaminating viral sequences in high-throughput sequencing viromics: a linkage study of 700 sequencing libraries.

Asplund M, Kjartansdóttir KR, Mollerup S, Vinner L, Fridholm H, Herrera JAR, Friis-Nielsen J, Hansen TA, Jensen RH, Nielsen IB, Richter SR, Rey-Iglesia A, Matey-Hernandez ML, Alquezar-Planas DE, Olsen PVS, Sicheritz-Pontén T, Willerslev E, Lund O, Brunak S, Mourier T, Nielsen LP, Izarzugaza JMG, Hansen AJ.

Clin Microbiol Infect. 2019 May 4. pii: S1198-743X(19)30206-X. doi: 10.1016/j.cmi.2019.04.028. [Epub ahead of print]

8.

Comorbidity landscape of the Danish patient population affected by chromosome abnormalities.

Jørgensen IF, Russo F, Jensen AB, Westergaard D, Lademann M, Hu JX, Brunak S, Belling K.

Genet Med. 2019 Apr 25. doi: 10.1038/s41436-019-0519-9. [Epub ahead of print]

PMID:
31019277
9.

Roadmap for a precision-medicine initiative in the Nordic region.

Njølstad PR, Andreassen OA, Brunak S, Børglum AD, Dillner J, Esko T, Franks PW, Freimer N, Groop L, Heimer H, Hougaard DM, Hovig E, Hveem K, Jalanko A, Kaprio J, Knudsen GP, Melbye M, Metspalu A, Mortensen PB, Palmgren J, Palotie A, Reed W, Stefánsson H, Stitziel NO, Sullivan PF, Thorsteinsdóttir U, Vaudel M, Vuorio E, Werge T, Stoltenberg C, Stefánsson K.

Nat Genet. 2019 Jun;51(6):924-930. doi: 10.1038/s41588-019-0391-1. No abstract available.

PMID:
30988515
10.

Combing the Hairball: Improving Visualization of miRNA-Target Interaction Networks.

Russo F, Hu JX, Romero Herrera JA, Brunak S.

Methods Mol Biol. 2019;1970:279-289. doi: 10.1007/978-1-4939-9207-2_15.

PMID:
30963498
11.

[Infrastructure of clinical support and research in the Danish national genome centre].

Ørntoft TF, Brunak S, Jespergaard C, Heickendorff L, Grønkjær K, Løngreen P.

Ugeskr Laeger. 2019 Apr 1;181(7A). pii: V02190076. Danish.

PMID:
30950376
12.

Conflicting associations between dietary patterns and changes of anthropometric traits across subgroups of middle-aged women and men.

Jiang L, Audouze K, Romero Herrera JA, Ängquist LH, Kjærulff SK, Izarzugaza JMG, Tjønneland A, Halkjær J, Overvad K, Sørensen TIA, Brunak S.

Clin Nutr. 2019 Feb 14. pii: S0261-5614(19)30055-X. doi: 10.1016/j.clnu.2019.02.003. [Epub ahead of print]

13.

SignalP 5.0 improves signal peptide predictions using deep neural networks.

Almagro Armenteros JJ, Tsirigos KD, Sønderby CK, Petersen TN, Winther O, Brunak S, von Heijne G, Nielsen H.

Nat Biotechnol. 2019 Apr;37(4):420-423. doi: 10.1038/s41587-019-0036-z. Epub 2019 Feb 18.

PMID:
30778233
14.

Population-wide analysis of differences in disease progression patterns in men and women.

Westergaard D, Moseley P, Sørup FKH, Baldi P, Brunak S.

Nat Commun. 2019 Feb 8;10(1):666. doi: 10.1038/s41467-019-08475-9.

15.

Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders.

Burgdorf KS, Trabjerg BB, Pedersen MG, Nissen J, Banasik K, Pedersen OB, Sørensen E, Nielsen KR, Larsen MH, Erikstrup C, Bruun-Rasmussen P, Westergaard D, Thørner LW, Hjalgrim H, Paarup HM, Brunak S, Pedersen CB, Torrey EF, Werge T, Mortensen PB, Yolken RH, Ullum H.

Brain Behav Immun. 2019 Jul;79:152-158. doi: 10.1016/j.bbi.2019.01.026. Epub 2019 Jan 29.

16.

A Large-Cohort, Longitudinal Study Determines Precancer Disease Routes across Different Cancer Types.

Hu JX, Helleberg M, Jensen AB, Brunak S, Lundgren J.

Cancer Res. 2019 Feb 15;79(4):864-872. doi: 10.1158/0008-5472.CAN-18-1677. Epub 2018 Dec 27.

PMID:
30591553
17.

A computational framework to integrate high-throughput '-omics' datasets for the identification of potential mechanistic links.

Pedersen HK, Forslund SK, Gudmundsdottir V, Petersen AØ, Hildebrand F, Hyötyläinen T, Nielsen T, Hansen T, Bork P, Ehrlich SD, Brunak S, Oresic M, Pedersen O, Nielsen HB.

Nat Protoc. 2018 Dec;13(12):2781-2800. doi: 10.1038/s41596-018-0064-z.

PMID:
30382244
18.

A Novel Familial Cardiac Arrhythmia Syndrome with Widespread ST-Segment Depression.

Bundgaard H, Jøns C, Lodder EM, Izarzugaza JMG, Romero Herrera JA, Pehrson S, Tfelt-Hansen J, Ahlberg G, Olesen MS, Holst AG, Wellens H, de Villiers C, Hastings R, Stuart G, Brunak S, Wilde AAM, Watkins H, Christensen AH.

N Engl J Med. 2018 Nov 1;379(18):1780-1781. doi: 10.1056/NEJMc1807668. No abstract available.

PMID:
30380381
19.

Increase in clinically recorded type 2 diabetes after colectomy.

Jensen AB, Sørensen TI, Pedersen O, Jess T, Brunak S, Allin KH.

Elife. 2018 Oct 30;7. pii: e37420. doi: 10.7554/eLife.37420.

20.

Protective role of the vulture facial skin and gut microbiomes aid adaptation to scavenging.

Zepeda Mendoza ML, Roggenbuck M, Manzano Vargas K, Hansen LH, Brunak S, Gilbert MTP, Sicheritz-Pontén T.

Acta Vet Scand. 2018 Oct 11;60(1):61. doi: 10.1186/s13028-018-0415-3.

21.

Analysis of Time-Series Gene Expression Data to Explore Mechanisms of Chemical-Induced Hepatic Steatosis Toxicity.

Aguayo-Orozco A, Bois FY, Brunak S, Taboureau O.

Front Genet. 2018 Sep 18;9:396. doi: 10.3389/fgene.2018.00396. eCollection 2018.

22.

[Precision cardiology].

Haue AD, Vissing CR, Tfelt-Hansen J, Brunak S, Bundgaard H, Weeke PE.

Ugeskr Laeger. 2018 Oct 1;180(20A). pii: V07180484. Danish.

PMID:
30274592
23.

The governance structure for data access in the DIRECT consortium: an innovative medicines initiative (IMI) project.

Teare HJA, de Masi F, Banasik K, Barnett A, Herrgard S, Jablonka B, Postma JWM, McDonald TJ, Forgie I, Chmura PJ, Rydzka EK, Gupta R, Brunak S, Pearson E, Kaye J.

Life Sci Soc Policy. 2018 Sep 4;14(1):20. doi: 10.1186/s40504-018-0083-0.

24.

A generic deep convolutional neural network framework for prediction of receptor-ligand interactions-NetPhosPan: application to kinase phosphorylation prediction.

Fenoy E, Izarzugaza JMG, Jurtz V, Brunak S, Nielsen M.

Bioinformatics. 2019 Apr 1;35(7):1098-1107. doi: 10.1093/bioinformatics/bty715.

PMID:
30169744
25.

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers.

Tsafou K, Katschnig AM, Radic-Sarikas B, Mutz CN, Iljin K, Schwentner R, Kauer MO, Mühlbacher K, Aryee DNT, Westergaard D, Haapa-Paananen S, Fey V, Superti-Furga G, Toretsky J, Brunak S, Kovar H.

Oncotarget. 2018 Jul 24;9(57):31018-31031. doi: 10.18632/oncotarget.25760. eCollection 2018 Jul 24.

26.

Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios.

Matey-Hernandez ML; Danish Pan Genome Consortium, Brunak S, Izarzugaza JMG.

BMC Bioinformatics. 2018 Jun 25;19(1):239. doi: 10.1186/s12859-018-2239-6.

27.

Retinoic Acid Signaling in Thymic Epithelial Cells Regulates Thymopoiesis.

Wendland K, Niss K, Kotarsky K, Wu NYH, White AJ, Jendholm J, Rivollier A, Izarzugaza JMG, Brunak S, Holländer GA, Anderson G, Sitnik KM, Agace WW.

J Immunol. 2018 Jul 15;201(2):524-532. doi: 10.4049/jimmunol.1800418. Epub 2018 May 30.

28.

Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells.

Winge SB, Dalgaard MD, Belling KG, Jensen JM, Nielsen JE, Aksglaede L, Schierup MH, Brunak S, Skakkebæk NE, Juul A, Rajpert-De Meyts E, Almstrup K.

Cell Death Dis. 2018 May 22;9(6):586. doi: 10.1038/s41419-018-0671-1.

29.

Unexplored therapeutic opportunities in the human genome.

Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G.

Nat Rev Drug Discov. 2018 May;17(5):377. doi: 10.1038/nrd.2018.52. Epub 2018 Mar 23.

PMID:
29567993
30.

Analysis of a gene panel for targeted sequencing of colorectal cancer samples.

Jensen KH, Izarzugaza JMG, Juncker AS, Hansen RB, Hansen TF, Timshel P, Blondal T, Jensen TS, Rygaard-Hjalsted E, Mouritzen P, Thorsen M, Wernersson R, Nielsen HB, Jakobsen A, Brunak S, Sørensen FB.

Oncotarget. 2018 Jan 10;9(10):9043-9060. doi: 10.18632/oncotarget.24138. eCollection 2018 Feb 6.

31.

Unexplored therapeutic opportunities in the human genome.

Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G.

Nat Rev Drug Discov. 2018 May;17(5):317-332. doi: 10.1038/nrd.2018.14. Epub 2018 Mar 23. Review. Erratum in: Nat Rev Drug Discov. 2018 Mar 23;:.

32.

The protein kinase SIK downregulates the polarity protein Par3.

Vanlandewijck M, Dadras MS, Lomnytska M, Mahzabin T, Lee Miller M, Busch C, Brunak S, Heldin CH, Moustakas A.

Oncotarget. 2017 Dec 31;9(5):5716-5735. doi: 10.18632/oncotarget.23788. eCollection 2018 Jan 19.

33.

A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts.

Westergaard D, Stærfeldt HH, Tønsberg C, Jensen LJ, Brunak S.

PLoS Comput Biol. 2018 Feb 15;14(2):e1005962. doi: 10.1371/journal.pcbi.1005962. eCollection 2018 Feb.

34.

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism.

Kristensen DM, Desdoits-Lethimonier C, Mackey AL, Dalgaard MD, De Masi F, Munkbøl CH, Styrishave B, Antignac JP, Le Bizec B, Platel C, Hay-Schmidt A, Jensen TK, Lesné L, Mazaud-Guittot S, Kristiansen K, Brunak S, Kjaer M, Juul A, Jégou B.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E715-E724. doi: 10.1073/pnas.1715035115. Epub 2018 Jan 8. Erratum in: Proc Natl Acad Sci U S A. 2018 Apr 16;:.

35.

Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study.

Gudmundsdottir V, Pedersen HK, Allebrandt KV, Brorsson C, van Leeuwen N, Banasik K, Mahajan A, Groves CJ, van de Bunt M, Dawed AY, Fritsche A, Staiger H, Simonis-Bik AMC, Deelen J, Kramer MHH, Dietrich A, Hübschle T, Willemsen G, Häring HU, de Geus EJC, Boomsma DI, Eekhoff EMW, Ferrer J, McCarthy MI, Pearson ER, Gupta R, Brunak S, 't Hart LM.

PLoS One. 2018 Jan 2;13(1):e0189886. doi: 10.1371/journal.pone.0189886. eCollection 2018.

36.

Familial co-occurrence of congenital heart defects follows distinct patterns.

Ellesøe SG, Workman CT, Bouvagnet P, Loffredo CA, McBride KL, Hinton RB, van Engelen K, Gertsen EC, Mulder BJM, Postma AV, Anderson RH, Hjortdal VE, Brunak S, Larsen LA.

Eur Heart J. 2018 Mar 21;39(12):1015-1022. doi: 10.1093/eurheartj/ehx314.

37.

miRandola 2017: a curated knowledge base of non-invasive biomarkers.

Russo F, Di Bella S, Vannini F, Berti G, Scoyni F, Cook HV, Santos A, Nigita G, Bonnici V, Laganà A, Geraci F, Pulvirenti A, Giugno R, De Masi F, Belling K, Jensen LJ, Brunak S, Pellegrini M, Ferro A.

Nucleic Acids Res. 2018 Jan 4;46(D1):D354-D359. doi: 10.1093/nar/gkx854.

38.

Legacy data sharing to improve drug safety assessment: the eTOX project.

Sanz F, Pognan F, Steger-Hartmann T, Díaz C; eTOX, Cases M, Pastor M, Marc P, Wichard J, Briggs K, Watson DK, Kleinöder T, Yang C, Amberg A, Beaumont M, Brookes AJ, Brunak S, Cronin MTD, Ecker GF, Escher S, Greene N, Guzmán A, Hersey A, Jacques P, Lammens L, Mestres J, Muster W, Northeved H, Pinches M, Saiz J, Sajot N, Valencia A, van der Lei J, Vermeulen NPE, Vock E, Wolber G, Zamora I.

Nat Rev Drug Discov. 2017 Dec;16(12):811-812. doi: 10.1038/nrd.2017.177. Epub 2017 Oct 13.

PMID:
29026211
39.

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study.

Molnos S, Wahl S, Haid M, Eekhoff EMW, Pool R, Floegel A, Deelen J, Much D, Prehn C, Breier M, Draisma HH, van Leeuwen N, Simonis-Bik AMC, Jonsson A, Willemsen G, Bernigau W, Wang-Sattler R, Suhre K, Peters A, Thorand B, Herder C, Rathmann W, Roden M, Gieger C, Kramer MHH, van Heemst D, Pedersen HK, Gudmundsdottir V, Schulze MB, Pischon T, de Geus EJC, Boeing H, Boomsma DI, Ziegler AG, Slagboom PE, Hummel S, Beekman M, Grallert H, Brunak S, McCarthy MI, Gupta R, Pearson ER, Adamski J, 't Hart LM.

Diabetologia. 2018 Jan;61(1):117-129. doi: 10.1007/s00125-017-4436-7. Epub 2017 Oct 25.

40.

The impact of the protein interactome on the syntenic structure of mammalian genomes.

Kirk IK, Weinhold N, Brunak S, Belling K.

PLoS One. 2017 Sep 14;12(9):e0179112. doi: 10.1371/journal.pone.0179112. eCollection 2017.

41.

Sequencing and de novo assembly of 150 genomes from Denmark as a population reference.

Maretty L, Jensen JM, Petersen B, Sibbesen JA, Liu S, Villesen P, Skov L, Belling K, Theil Have C, Izarzugaza JMG, Grosjean M, Bork-Jensen J, Grove J, Als TD, Huang S, Chang Y, Xu R, Ye W, Rao J, Guo X, Sun J, Cao H, Ye C, van Beusekom J, Espeseth T, Flindt E, Friborg RM, Halager AE, Le Hellard S, Hultman CM, Lescai F, Li S, Lund O, Løngren P, Mailund T, Matey-Hernandez ML, Mors O, Pedersen CNS, Sicheritz-Pontén T, Sullivan P, Syed A, Westergaard D, Yadav R, Li N, Xu X, Hansen T, Krogh A, Bolund L, Sørensen TIA, Pedersen O, Gupta R, Rasmussen S, Besenbacher S, Børglum AD, Wang J, Eiberg H, Kristiansen K, Brunak S, Schierup MH.

Nature. 2017 Aug 3;548(7665):87-91. doi: 10.1038/nature23264. Epub 2017 Jul 26.

PMID:
28746312
42.

Protein features as determinants of wild-type glycoside hydrolase thermostability.

Geertz-Hansen HM, Kiemer L, Nielsen M, Stanchev K, Blom N, Brunak S, Petersen TN.

Proteins. 2017 Nov;85(11):2036-2044. doi: 10.1002/prot.25357. Epub 2017 Aug 10.

PMID:
28734034
43.

Lapatinib potentiates cytotoxicity of  YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter.

Radic-Sarikas B, Halasz M, Huber KVM, Winter GE, Tsafou KP, Papamarkou T, Brunak S, Kolch W, Superti-Furga G.

Sci Rep. 2017 Jun 8;7(1):3091. doi: 10.1038/s41598-017-03129-6.

44.

Prenatal exposure to paracetamol/acetaminophen and precursor aniline impairs masculinisation of male brain and behaviour.

Hay-Schmidt A, Finkielman OTE, Jensen BAH, Høgsbro CF, Bak Holm J, Johansen KH, Jensen TK, Andrade AM, Swan SH, Bornehag CG, Brunak S, Jegou B, Kristiansen K, Kristensen DM.

Reproduction. 2017 Aug;154(2):145-152. doi: 10.1530/REP-17-0165. Epub 2017 May 30.

45.

Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes.

Pedersen HK, Gudmundsdottir V, Brunak S.

Front Genet. 2017 Apr 20;8:43. doi: 10.3389/fgene.2017.00043. eCollection 2017.

46.

Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.

Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chatelier E, Sunagawa S, Prifti E, Vieira-Silva S, Gudmundsdottir V, Pedersen HK, Arumugam M, Kristiansen K, Voigt AY, Vestergaard H, Hercog R, Costea PI, Kultima JR, Li J, Jørgensen T, Levenez F, Dore J; MetaHIT consortium, Nielsen HB, Brunak S, Raes J, Hansen T, Wang J, Ehrlich SD, Bork P, Pedersen O.

Nature. 2017 May 3;545(7652):116. doi: 10.1038/nature22318. No abstract available.

PMID:
28470190
47.

MicroRNAs, Regulatory Networks, and Comorbidities: Decoding Complex Systems.

Russo F, Belling K, Jensen AB, Scoyni F, Brunak S, Pellegrini M.

Methods Mol Biol. 2017;1580:281-295. doi: 10.1007/978-1-4939-6866-4_19.

PMID:
28439840
48.

Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity.

Belling K, Russo F, Jensen AB, Dalgaard MD, Westergaard D, Rajpert-De Meyts E, Skakkebæk NE, Juul A, Brunak S.

Hum Mol Genet. 2017 Apr 1;26(7):1219-1229. doi: 10.1093/hmg/ddx014.

49.

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.

Folkersen L, Fauman E, Sabater-Lleal M, Strawbridge RJ, Frånberg M, Sennblad B, Baldassarre D, Veglia F, Humphries SE, Rauramaa R, de Faire U, Smit AJ, Giral P, Kurl S, Mannarino E, Enroth S, Johansson Å, Enroth SB, Gustafsson S, Lind L, Lindgren C, Morris AP, Giedraitis V, Silveira A, Franco-Cereceda A, Tremoli E; IMPROVE study group, Gyllensten U, Ingelsson E, Brunak S, Eriksson P, Ziemek D, Hamsten A, Mälarstig A.

PLoS Genet. 2017 Apr 3;13(4):e1006706. doi: 10.1371/journal.pgen.1006706. eCollection 2017 Apr.

50.

Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer.

Francavilla C, Lupia M, Tsafou K, Villa A, Kowalczyk K, Rakownikow Jersie-Christensen R, Bertalot G, Confalonieri S, Brunak S, Jensen LJ, Cavallaro U, Olsen JV.

Cell Rep. 2017 Mar 28;18(13):3242-3256. doi: 10.1016/j.celrep.2017.03.015.

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