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Items: 1 to 50 of 58

1.

A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation.

Castroviejo-Bermejo M, Cruz C, Llop-Guevara A, Gutiérrez-Enríquez S, Ducy M, Ibrahim YH, Gris-Oliver A, Pellegrino B, Bruna A, Guzmán M, Rodríguez O, Grueso J, Bonache S, Moles-Fernández A, Villacampa G, Viaplana C, Gómez P, Vidal M, Peg V, Serres-Créixams X, Dellaire G, Simard J, Nuciforo P, Rubio IT, Dientsmann R, Barrett JC, Caldas C, Baselga J, Saura C, Cortés J, Déas O, Jonkers J, Masson JY, Cairo S, Judde JG, O'Connor MJ, Díez O, Balmaña J, Serra V.

EMBO Mol Med. 2018 Oct 30. pii: e9172. doi: 10.15252/emmm.201809172. [Epub ahead of print]

2.

SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis.

Vervoort SJ, Lourenço AR, Tufegdzic Vidakovic A, Mocholi E, Sandoval JL, Rueda OM, Frederiks C, Pals C, Peeters JGC, Caldas C, Bruna A, Coffer PJ.

Nucleic Acids Res. 2018 Oct 12;46(18):9578-9590. doi: 10.1093/nar/gky755.

3.

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

Dev H, Chiang TW, Lescale C, de Krijger I, Martin AG, Pilger D, Coates J, Sczaniecka-Clift M, Wei W, Ostermaier M, Herzog M, Lam J, Shea A, Demir M, Wu Q, Yang F, Fu B, Lai Z, Balmus G, Belotserkovskaya R, Serra V, O'Connor MJ, Bruna A, Beli P, Pellegrini L, Caldas C, Deriano L, Jacobs JJL, Galanty Y, Jackson SP.

Nat Cell Biol. 2018 Aug;20(8):954-965. doi: 10.1038/s41556-018-0140-1. Epub 2018 Jul 18.

PMID:
30022119
4.

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

Xue Z, Vis DJ, Bruna A, Sustic T, van Wageningen S, Batra AS, Rueda OM, Bosdriesz E, Caldas C, Wessels LFA, Bernards R.

Cell Res. 2018 Jul;28(7):719-729. doi: 10.1038/s41422-018-0044-4. Epub 2018 May 24.

5.

High USP6NL Levels in Breast Cancer Sustain Chronic AKT Phosphorylation and GLUT1 Stability Fueling Aerobic Glycolysis.

Avanzato D, Pupo E, Ducano N, Isella C, Bertalot G, Luise C, Pece S, Bruna A, Rueda OM, Caldas C, Di Fiore PP, Sapino A, Lanzetti L.

Cancer Res. 2018 Jul 1;78(13):3432-3444. doi: 10.1158/0008-5472.CAN-17-3018. Epub 2018 Apr 24.

6.

Safety of anesthesia for children with mucopolysaccharidoses: A retrospective analysis of 54 patients.

Scaravilli V, Zanella A, Ciceri V, Bosatra M, Flandoli C, La Bruna A, Sosio S, Parini R, Gasperini S, Pesenti A, Moretto A.

Paediatr Anaesth. 2018 May;28(5):436-442. doi: 10.1111/pan.13379. Epub 2018 Apr 23.

PMID:
29687523
7.

RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer.

Cruz C, Castroviejo-Bermejo M, Gutiérrez-Enríquez S, Llop-Guevara A, Ibrahim YH, Gris-Oliver A, Bonache S, Morancho B, Bruna A, Rueda OM, Lai Z, Polanska UM, Jones GN, Kristel P, de Bustos L, Guzman M, Rodríguez O, Grueso J, Montalban G, Caratú G, Mancuso F, Fasani R, Jiménez J, Howat WJ, Dougherty B, Vivancos A, Nuciforo P, Serres-Créixams X, Rubio IT, Oaknin A, Cadogan E, Barrett JC, Caldas C, Baselga J, Saura C, Cortés J, Arribas J, Jonkers J, Díez O, O'Connor MJ, Balmaña J, Serra V.

Ann Oncol. 2018 May 1;29(5):1203-1210. doi: 10.1093/annonc/mdy099.

8.

Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts.

Callari M, Batra AS, Batra RN, Sammut SJ, Greenwood W, Clifford H, Hercus C, Chin SF, Bruna A, Rueda OM, Caldas C.

BMC Genomics. 2018 Jan 5;19(1):19. doi: 10.1186/s12864-017-4414-y.

9.

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.

Meehan TF, Conte N, Goldstein T, Inghirami G, Murakami MA, Brabetz S, Gu Z, Wiser JA, Dunn P, Begley DA, Krupke DM, Bertotti A, Bruna A, Brush MH, Byrne AT, Caldas C, Christie AL, Clark DA, Dowst H, Dry JR, Doroshow JH, Duchamp O, Evrard YA, Ferretti S, Frese KK, Goodwin NC, Greenawalt D, Haendel MA, Hermans E, Houghton PJ, Jonkers J, Kemper K, Khor TO, Lewis MT, Lloyd KCK, Mason J, Medico E, Neuhauser SB, Olson JM, Peeper DS, Rueda OM, Seong JK, Trusolino L, Vinolo E, Wechsler-Reya RJ, Weinstock DM, Welm A, Weroha SJ, Amant F, Pfister SM, Kool M, Parkinson H, Butte AJ, Bult CJ.

Cancer Res. 2017 Nov 1;77(21):e62-e66. doi: 10.1158/0008-5472.CAN-17-0582.

10.

Interrogating open issues in cancer medicine with patient-derived xenografts.

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E, Marine JC, Medico E, Norum JH, Palmer HG, Peeper DS, Pelicci PG, Piris-Gimenez A, Roman-Roman S, Rueda OM, Seoane J, Serra V, Soucek L, Vanhecke D, Villanueva A, Vinolo E, Bertotti A, Trusolino L.

Nat Rev Cancer. 2017 Sep 15;17(10):632. doi: 10.1038/nrc.2017.85. [Epub ahead of print]

PMID:
28912576
11.

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.

Tacconi EM, Lai X, Folio C, Porru M, Zonderland G, Badie S, Michl J, Sechi I, Rogier M, Matía García V, Batra AS, Rueda OM, Bouwman P, Jonkers J, Ryan A, Reina-San-Martin B, Hui J, Tang N, Bruna A, Biroccio A, Tarsounas M.

EMBO Mol Med. 2017 Oct;9(10):1398-1414. doi: 10.15252/emmm.201607446.

12.

Intersect-then-combine approach: improving the performance of somatic variant calling in whole exome sequencing data using multiple aligners and callers.

Callari M, Sammut SJ, De Mattos-Arruda L, Bruna A, Rueda OM, Chin SF, Caldas C.

Genome Med. 2017 Apr 18;9(1):35. doi: 10.1186/s13073-017-0425-1.

13.

Modeling Breast Cancer Intertumor and Intratumor Heterogeneity Using Xenografts.

Bruna A, Rueda OM, Caldas C.

Cold Spring Harb Symp Quant Biol. 2016;81:227-230. doi: 10.1101/sqb.2016.81.031112. Epub 2017 Apr 5. Review.

PMID:
28381438
14.

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E, Marine JC, Medico E, Norum JH, Palmer HG, Peeper DS, Pelicci PG, Piris-Gimenez A, Roman-Roman S, Rueda OM, Seoane J, Serra V, Soucek L, Vanhecke D, Villanueva A, Vinolo E, Bertotti A, Trusolino L.

Nat Rev Cancer. 2017 Apr;17(4):254-268. doi: 10.1038/nrc.2016.140. Epub 2017 Jan 20. Review. Erratum in: Nat Rev Cancer. 2017 Sep 15;:.

15.

Affine Covariant Features for Fisheye Distortion Local Modeling.

Furnari A, Farinella GM, Bruna AR, Battiato S.

IEEE Trans Image Process. 2017 Feb;26(2):696-710. doi: 10.1109/TIP.2016.2627816. Epub 2016 Nov 10.

PMID:
27849539
16.

Patient-derived tumour xenografts for breast cancer drug discovery.

Cassidy JW, Batra AS, Greenwood W, Bruna A.

Endocr Relat Cancer. 2016 Dec;23(12):T259-T270. Epub 2016 Oct 4. Review.

17.

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

Bruna A, Rueda OM, Greenwood W, Batra AS, Callari M, Batra RN, Pogrebniak K, Sandoval J, Cassidy JW, Tufegdzic-Vidakovic A, Sammut SJ, Jones L, Provenzano E, Baird R, Eirew P, Hadfield J, Eldridge M, McLaren-Douglas A, Barthorpe A, Lightfoot H, O'Connor MJ, Gray J, Cortes J, Baselga J, Marangoni E, Welm AL, Aparicio S, Serra V, Garnett MJ, Caldas C.

Cell. 2016 Sep 22;167(1):260-274.e22. doi: 10.1016/j.cell.2016.08.041. Epub 2016 Sep 15.

18.

PCR-specific detection of recently described Lotmaria passim (Trypanosomatidae) in Chilean apiaries.

Arismendi N, Bruna A, Zapata N, Vargas M.

J Invertebr Pathol. 2016 Feb;134:1-5. doi: 10.1016/j.jip.2015.12.008. Epub 2015 Dec 22.

PMID:
26721451
19.

Context-Specific Effects of TGF-β/SMAD3 in Cancer Are Modulated by the Epigenome.

Tufegdzic Vidakovic A, Rueda OM, Vervoort SJ, Sati Batra A, Goldgraben MA, Uribe-Lewis S, Greenwood W, Coffer PJ, Bruna A, Caldas C.

Cell Rep. 2015 Dec 22;13(11):2480-2490. doi: 10.1016/j.celrep.2015.11.040. Epub 2015 Dec 10.

20.

Corrigendum: Progesterone receptor modulates ERα action in breast cancer.

Mohammed H, Russell IA, Stark R, Rueda OM, Hickey TE, Tarulli GA, Serandour AA, Birrell SN, Bruna A, Saadi A, Menon S, Hadfield J, Pugh M, Raj GV, Brown GD, D'Santos C, Robinson JL, Silva G, Launchbury R, Perou CM, Stingl J, Caldas C, Tilley WD, Carroll JS.

Nature. 2015 Oct 1;526(7571):144. doi: 10.1038/nature14959. Epub 2015 Aug 5. No abstract available.

PMID:
26245370
21.

Maintaining Tumor Heterogeneity in Patient-Derived Tumor Xenografts.

Cassidy JW, Caldas C, Bruna A.

Cancer Res. 2015 Aug 1;75(15):2963-8. doi: 10.1158/0008-5472.CAN-15-0727. Epub 2015 Jul 15. Review.

22.

Progesterone receptor modulates ERα action in breast cancer.

Mohammed H, Russell IA, Stark R, Rueda OM, Hickey TE, Tarulli GA, Serandour AA, Birrell SN, Bruna A, Saadi A, Menon S, Hadfield J, Pugh M, Raj GV, Brown GD, D'Santos C, Robinson JL, Silva G, Launchbury R, Perou CM, Stingl J, Caldas C, Tilley WD, Carroll JS.

Nature. 2015 Jul 16;523(7560):313-7. doi: 10.1038/nature14583. Epub 2015 Jul 8. Erratum in: Nature. 2015 Oct 1;526(7571):144. Serandour, Aurelien A A[Corrected to Serandour, Aurelien A].

23.

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.

Eirew P, Steif A, Khattra J, Ha G, Yap D, Farahani H, Gelmon K, Chia S, Mar C, Wan A, Laks E, Biele J, Shumansky K, Rosner J, McPherson A, Nielsen C, Roth AJ, Lefebvre C, Bashashati A, de Souza C, Siu C, Aniba R, Brimhall J, Oloumi A, Osako T, Bruna A, Sandoval JL, Algara T, Greenwood W, Leung K, Cheng H, Xue H, Wang Y, Lin D, Mungall AJ, Moore R, Zhao Y, Lorette J, Nguyen L, Huntsman D, Eaves CJ, Hansen C, Marra MA, Caldas C, Shah SP, Aparicio S.

Nature. 2015 Feb 19;518(7539):422-6. doi: 10.1038/nature13952. Epub 2014 Nov 26.

24.

[Bipolar disorder: staging and neuroprogression].

Rodrigues AA, Rosa AR, Kunz M, Bruna A, Kapczinski F.

Psychiatr Pol. 2014 Mar-Apr;48(2):231-43. Review. Polish.

PMID:
25016762
25.

Exercise training and obesity in Italian children directly assessed by primary school teachers with tele-cardiology support: a pilot experience.

Brunetti ND, Conoscitore AR, Dellegrottaglie G, Di Giuseppe G, De Gennaro L, Antonelli G, Bruna A, Di Biase M.

Int J Cardiol. 2013 Sep 30;168(2):1699-702. doi: 10.1016/j.ijcard.2013.03.070. Epub 2013 Apr 18. No abstract available.

PMID:
23602871
26.

Forgery detection and value identification of Euro banknotes.

Bruna A, Farinella GM, Guarnera GC, Battiato S.

Sensors (Basel). 2013 Feb 18;13(2):2515-29. doi: 10.3390/s130202515.

27.

Chilean version of the INECO Frontal Screening (IFS-Ch): psychometric properties and diagnostic accuracy.

Jory JI, Bruna AA, Muñoz-Neira C, Chonchol AS.

Dement Neuropsychol. 2013 Jan-Mar;7(1):40-47. doi: 10.1590/S1980-57642013DN70100007.

28.

TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer.

Bruna A, Greenwood W, Le Quesne J, Teschendorff A, Miranda-Saavedra D, Rueda OM, Sandoval JL, Vidakovic AT, Saadi A, Pharoah P, Stingl J, Caldas C.

Nat Commun. 2012;3:1055. doi: 10.1038/ncomms2039.

PMID:
22968701
29.

Color space transformations for digital photography exploiting information about the illuminant estimation process.

Bianco S, Bruna A, Naccari F, Schettini R.

J Opt Soc Am A Opt Image Sci Vis. 2012 Mar 1;29(3):374-84. doi: 10.1364/JOSAA.29.000374.

PMID:
22472769
30.

[Prevalence of breastfeeding in the Verbano-Cusio-Ossola region].

Guala A, Boscardini L, Azioni L, Bruna A, Cantalupi L, Censini S, Chiaberta D, Comaita F, De Nicolò E, Del Ponte G, Federico MG, Godi MT, Luotti D, Perlino G, Santini I.

Pediatr Med Chir. 2011 Mar-Apr;33(2):104. Italian. No abstract available.

PMID:
22111297
31.

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium.

Holland DG, Burleigh A, Git A, Goldgraben MA, Perez-Mancera PA, Chin SF, Hurtado A, Bruna A, Ali HR, Greenwood W, Dunning MJ, Samarajiwa S, Menon S, Rueda OM, Lynch AG, McKinney S, Ellis IO, Eaves CJ, Carroll JS, Curtis C, Aparicio S, Caldas C.

EMBO Mol Med. 2011 Mar;3(3):167-80. doi: 10.1002/emmm.201100122. Epub 2011 Feb 18.

32.

[Feasibility and toxicity of a single fraction high-dose-rate brachytherapy followed by a course of EBRT for localized prostate cancer: a retrospective study. The Polyclinique Courlancy experience].

Mallet F, Wdowczyk D, Bruna A, Villena P, Herard A, Amory JP, Joffroy P, Pangrazzi T.

Cancer Radiother. 2010 Jan;14(1):11-8. doi: 10.1016/j.canrad.2009.10.003. Epub 2009 Dec 14. French.

PMID:
20005765
33.

Stem cell signaling in newly diagnosed, antipsychotic-naive subjects with nonaffective psychosis.

Fernandez-Egea E, Bruna A, Garcia-Rizo C, Bernardo M, Kirkpatrick B.

Mol Psychiatry. 2009 Nov;14(11):989-91. doi: 10.1038/mp.2009.45. No abstract available.

34.

Developmental dilatation of Virchow-Robin spaces: a genetic disorder?

Bruna AL, Martins I, Husson B, Landrieu P.

Pediatr Neurol. 2009 Oct;41(4):275-80. doi: 10.1016/j.pediatrneurol.2009.04.026.

PMID:
19748047
35.

Noise Reduction for CFA Image Sensors Exploiting HVS Behaviour.

Bosco A, Battiato S, Bruna A, Rizzo R.

Sensors (Basel). 2009;9(3):1692-713. doi: 10.3390/s90301692. Epub 2009 Mar 10.

36.

[Radiotherapy and targeted therapies in head and neck carcinomas and NSCLC].

Bruna A, Bourhis J.

Bull Cancer. 2009;96 Suppl 1:65-8. doi: 10.1684/bdc.2009.0788. Review. French.

PMID:
19433375
37.

[Chronic disease and childhood: image of the body, psychic stakes and therapeutic alliance].

Bouquinet E, Balestra J, Bismuth E, Bruna AL, Gallet S, Harvet G, Jean S, Jousselme C.

Arch Pediatr. 2008 Apr;15(4):462-8. doi: 10.1016/j.arcped.2008.01.008. Epub 2008 Mar 5. French.

PMID:
18321691
38.

High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene.

Bruna A, Darken RS, Rojo F, Ocaña A, Peñuelas S, Arias A, Paris R, Tortosa A, Mora J, Baselga J, Seoane J.

Cancer Cell. 2007 Feb;11(2):147-60.

39.

[Small cell lung cancer (CPC). Management of patients presenting with limited stage small cell carcinoma of the lung].

Le Péchoux C, Besse B, Ferreira I, Bretel JJ, Bruna A, Mazeron R, Amarouch A, Roberti E.

Rev Mal Respir. 2006 Nov;23(5 Pt 3):16S188-16S197. Review. French.

PMID:
17268357
40.

[Lung cancer: is there a place for elective nodal irradiation?].

Le Péchoux C, Ferreira I, Bruna A, Roberti E, Besse B, Bretel JJ.

Cancer Radiother. 2006 Nov;10(6-7):354-60. Epub 2006 Oct 10. Review. French.

PMID:
17035060
41.

[Prophylactic cranial irradiation in non-small cell lung cancer].

Mazeron R, Le Péchoux C, Bruna A, Amarouch A, Bretel JJ, Ferreira I.

Cancer Radiother. 2007 Jan-Feb;11(1-2):84-91. Epub 2006 Sep 26. Review. French.

PMID:
17005429
42.

Treatment of squamous cell anal canal carcinoma (SCACC) with pulsed dose rate brachytherapy: a retrospective study.

Bruna A, Gastelblum P, Thomas L, Chapet O, Bollet MA, Ardiet JM, Gérard JP, Peiffert D.

Radiother Oncol. 2006 Apr;79(1):75-9.

PMID:
16631268
43.

[Medical treatment of metastatic or recurrent cancer of the cervix].

de la Motte Rouge T, Pautier P, Hamy AS, Duvillard P, Bruna A, Castaigne D, Morice P, Haie-Meder C, Lhommé C.

Bull Cancer. 2006 Mar 1;93(3):263-70. Review. French.

44.

[Concomitant chemoradiation in patients with cervix cancer].

Haie-Meder C, de Crevoisier R, Bruna A, Lhommé C, Pautier P, Morice P, Castaigne D, Bourhis J.

Bull Cancer. 2005 Dec;92(12):1032-8. Review. French.

45.

Anal canal carcinoma: early-stage tumors < or =10 mm (T1 or Tis): therapeutic options and original pattern of local failure after radiotherapy.

Ortholan C, Ramaioli A, Peiffert D, Lusinchi A, Romestaing P, Chauveinc L, Touboul E, Peignaux K, Bruna A, de La Roche G, Lagrange JL, Alzieu C, Gerard JP.

Int J Radiat Oncol Biol Phys. 2005 Jun 1;62(2):479-85.

PMID:
15890590
46.

[Use of the functional imaging modalities in radiation therapy treatment planning in patients with glioblastoma].

Dhermain F, Ducreux D, Bidault F, Bruna A, Parker F, Roujeau T, Beaudre A, Armand JP, Haie-Meder C.

Bull Cancer. 2005 Apr;92(4):333-42. Review. French.

47.

Glucocorticoid receptor-JNK interaction mediates inhibition of the JNK pathway by glucocorticoids.

Bruna A, Nicolàs M, Muñoz A, Kyriakis JM, Caelles C.

EMBO J. 2003 Nov 17;22(22):6035-44.

48.

Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis.

Jorda EG, Verdaguer E, Canudas AM, Jiménez A, Bruna A, Caelles C, Bravo R, Escubedo E, Pubill D, Camarasa J, Pallàs M, Camins A.

Neuropharmacology. 2003 Oct;45(5):672-83.

PMID:
12941380
49.

Glucocorticoid receptor antagonism of AP-1 activity by inhibition of MAPK family.

Caelles C, Bruna A, Morales M, González-Sancho JM, González MV, Jiménez B, Muñoz A.

Ernst Schering Res Found Workshop. 2002;(40):131-52. No abstract available.

PMID:
12355714
50.

Subcutaneous and retropharyngeal emphysema after dental procedures.

Szubin L, La Bruna A, Levine J, Komisar A.

Otolaryngol Head Neck Surg. 1997 Jul;117(1):122-3. No abstract available.

PMID:
9230336

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