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Items: 27


TgMAPK1 is a Toxoplasma gondii MAP kinase that hijacks host MKK3 signals to regulate virulence and interferon-γ-mediated nitric oxide production.

Brumlik MJ, Pandeswara S, Ludwig SM, Jeansonne DP, Lacey MR, Murthy K, Daniel BJ, Wang RF, Thibodeaux SR, Church KM, Hurez V, Kious MJ, Zhang B, Alagbala A, Xia X, Curiel TJ.

Exp Parasitol. 2013 Jul;134(3):389-99. doi: 10.1016/j.exppara.2013.03.016. Epub 2013 Mar 27.


Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice.

Hurez V, Daniel BJ, Sun L, Liu AJ, Ludwig SM, Kious MJ, Thibodeaux SR, Pandeswara S, Murthy K, Livi CB, Wall S, Brumlik MJ, Shin T, Zhang B, Curiel TJ.

Cancer Res. 2012 Apr 15;72(8):2089-99. doi: 10.1158/0008-5472.CAN-11-3019. Epub 2012 Apr 11.


Parasite mitogen-activated protein kinases as drug discovery targets to treat human protozoan pathogens.

Brumlik MJ, Pandeswara S, Ludwig SM, Murthy K, Curiel TJ.

J Signal Transduct. 2011;2011:971968. doi: 10.1155/2011/971968. Epub 2011 Feb 27.


Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication.

Brumlik MJ, Nkhoma S, Kious MJ, Thompson GR 3rd, Patterson TF, Siekierka JJ, Anderson TJ, Curiel TJ.

Exp Parasitol. 2011 Jun;128(2):170-5. doi: 10.1016/j.exppara.2011.02.016. Epub 2011 Feb 19.


Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b(+)Gr-1(+) cells.

Tomihara K, Guo M, Shin T, Sun X, Ludwig SM, Brumlik MJ, Zhang B, Curiel TJ, Shin T.

J Immunol. 2010 Jun 1;184(11):6151-60. doi: 10.4049/jimmunol.0903519. Epub 2010 Apr 28.


A simple method to detect Toxoplasma gondii-specific cytotoxic T cells in vivo.

Daniel BJ, Pandeswara S, Brumlik MJ, Liu A, Thibodeaux SR, Ludwig SM, Sun X, Curiel TJ.

J Immunol Methods. 2010 Apr 15;355(1-2):86-90. doi: 10.1016/j.jim.2010.01.013. Epub 2010 Feb 8.


Costimulator B7-DC attenuates strong Th2 responses induced by Nippostrongylus brasiliensis.

Ishiwata K, Watanabe N, Guo M, Tomihara K, Brumlik MJ, Yagita H, Pardoll D, Chen L, Shin T.

J Immunol. 2010 Feb 15;184(4):2086-94. doi: 10.4049/jimmunol.0804051. Epub 2010 Jan 11.


An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance.

Mitra D, Brumlik MJ, Okamgba SU, Zhu Y, Duplessis TT, Parvani JG, Lesko SM, Brogi E, Jones FE.

Mol Cancer Ther. 2009 Aug;8(8):2152-62. doi: 10.1158/1535-7163.MCT-09-0295. Epub 2009 Aug 11.


Altering regulatory T cell function in cancer immunotherapy: a novel means to boost the efficacy of cancer vaccines.

Ruter J, Barnett BG, Kryczek I, Brumlik MJ, Daniel BJ, Coukos G, Zou W, Curiel TJ.

Front Biosci (Landmark Ed). 2009 Jan 1;14:1761-70. Review.


Regulatory T cells: a new frontier in cancer immunotherapy.

Barnett BG, Rüter J, Kryczek I, Brumlik MJ, Cheng PJ, Daniel BJ, Coukos G, Zou W, Curiel TJ.

Adv Exp Med Biol. 2008;622:255-60. doi: 10.1007/978-0-387-68969-2_20. Review. No abstract available.


Trends in immunoconjugate and ligand-receptor based targeting development for cancer therapy.

Brumlik MJ, Daniel BJ, Waehler R, Curiel DT, Giles FJ, Curiel TJ.

Expert Opin Drug Deliv. 2008 Jan;5(1):87-103. Review.


Drugs designed to inhibit human p38 mitogen-activated protein kinase activation treat Toxoplasma gondii and Encephalitozoon cuniculi infection.

Wei S, Daniel BJ, Brumlik MJ, Burow ME, Zou W, Khan IA, Wadsworth S, Siekierka J, Curiel TJ.

Antimicrob Agents Chemother. 2007 Dec;51(12):4324-8. Epub 2007 Oct 8.


5S clavam biosynthetic genes are located in both the clavam and paralog gene clusters in Streptomyces clavuligerus.

Tahlan K, Anders C, Wong A, Mosher RH, Beatty PH, Brumlik MJ, Griffin A, Hughes C, Griffin J, Barton B, Jensen SE.

Chem Biol. 2007 Feb;14(2):131-42.


Toxoplasma gondii expresses two mitogen-activated protein kinase genes that represent distinct protozoan subfamilies.

Lacey MR, Brumlik MJ, Yenni RE, Burow ME, Curiel TJ.

J Mol Evol. 2007 Jan;64(1):4-14. Epub 2006 Dec 9.


Genetic diversity among Bacillus anthracis, Bacillus cereus and Bacillus thuringiensis strains using repetitive element polymorphism-PCR.

Brumlik MJ, Bielawska-Drózd A, Zakowska D, Liang X, Spalletta RA, Patra G, Delvecchio VG.

Pol J Microbiol. 2004;53(4):215-25.


Identification of a novel mitogen-activated protein kinase in Toxoplasma gondii.

Brumlik MJ, Wei S, Finstad K, Nesbit J, Hyman LE, Lacey M, Burow ME, Curiel TJ.

Int J Parasitol. 2004 Oct;34(11):1245-54.


Five additional genes are involved in clavulanic acid biosynthesis in Streptomyces clavuligerus.

Jensen SE, Paradkar AS, Mosher RH, Anders C, Beatty PH, Brumlik MJ, Griffin A, Barton B.

Antimicrob Agents Chemother. 2004 Jan;48(1):192-202.


Use of long-range repetitive element polymorphism-PCR to differentiate Bacillus anthracis strains.

Brumlik MJ, Szymajda U, Zakowska D, Liang X, Redkar RJ, Patra G, Del Vecchio VG.

Appl Environ Microbiol. 2001 Jul;67(7):3021-8.


A new family of lipolytic plant enzymes with members in rice, arabidopsis and maize.

Brick DJ, Brumlik MJ, Buckley JT, Cao JX, Davies PC, Misra S, Tranbarger TJ, Upton C.

FEBS Lett. 1995 Dec 27;377(3):475-80.


Zinc and iron regulate translation of the gene encoding Pseudomonas aeruginosa elastase.

Brumlik MJ, Storey DG.

Mol Microbiol. 1992 Feb;6(3):337-44.


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