Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 51

1.

Profiling the Targets of Protective CD8+ T Cell Responses to Infection.

Bruder JT, Chen P, Ekberg G, Smith EC, Lazarski CA, Myers BA, Bolton J, Sedegah M, Villasante E, Richie TL, King CR, Aguiar JC, Doolan DL, Brough DE.

Mol Ther Methods Clin Dev. 2017 Aug 18;7:20-31. doi: 10.1016/j.omtm.2017.08.003. eCollection 2017 Dec 15.

2.

New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model.

Limbach K, Stefaniak M, Chen P, Patterson NB, Liao G, Weng S, Krepkiy S, Ekberg G, Torano H, Ettyreddy D, Gowda K, Sonawane S, Belmonte A, Abot E, Sedegah M, Hollingdale MR, Moormann A, Vulule J, Villasante E, Richie TL, Brough DE, Bruder JT.

Malar J. 2017 Jul 3;16(1):263. doi: 10.1186/s12936-017-1911-z.

3.

A glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell responses induced by an adenovirus-vectored malaria vaccine in non-human primates.

Padte NN, Boente-Carrera M, Andrews CD, McManus J, Grasperge BF, Gettie A, Coelho-dos-Reis JG, Li X, Wu D, Bruder JT, Sedegah M, Patterson N, Richie TL, Wong CH, Ho DD, Vasan S, Tsuji M.

PLoS One. 2013 Oct 25;8(10):e78407. doi: 10.1371/journal.pone.0078407. eCollection 2013.

4.

Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled human malaria infection.

Tamminga C, Sedegah M, Maiolatesi S, Fedders C, Reyes S, Reyes A, Vasquez C, Alcorta Y, Chuang I, Spring M, Kavanaugh M, Ganeshan H, Huang J, Belmonte M, Abot E, Belmonte A, Banania J, Farooq F, Murphy J, Komisar J, Richie NO, Bennett J, Limbach K, Patterson NB, Bruder JT, Shi M, Miller E, Dutta S, Diggs C, Soisson LA, Hollingdale MR, Epstein JE, Richie TL.

Hum Vaccin Immunother. 2013 Oct;9(10):2165-77. doi: 10.4161/hv.24941. Epub 2013 Jun 4.

5.

Identification of a suppressor mutation that improves the yields of hexon-modified adenovirus vectors.

Bruder JT, Chen P, Semenova E, Thomas CA, Konovalova S, Ekberg G, Ettyreddy D, McVey D, Gall JG, King CR, Brough DE.

J Virol. 2013 Sep;87(17):9661-71. doi: 10.1128/JVI.00462-13. Epub 2013 Jul 3.

6.

Adenoviruses isolated from wild gorillas are closely related to human species C viruses.

Duncan M, Cranfield MR, Torano H, Kuete HM, Lee GP, Glenn A, Bruder JT, Rangel D, Brough DE, Gall JG.

Virology. 2013 Sep;444(1-2):119-23. doi: 10.1016/j.virol.2013.05.041. Epub 2013 Jun 24.

7.

DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity.

Chuang I, Sedegah M, Cicatelli S, Spring M, Polhemus M, Tamminga C, Patterson N, Guerrero M, Bennett JW, McGrath S, Ganeshan H, Belmonte M, Farooq F, Abot E, Banania JG, Huang J, Newcomer R, Rein L, Litilit D, Richie NO, Wood C, Murphy J, Sauerwein R, Hermsen CC, McCoy AJ, Kamau E, Cummings J, Komisar J, Sutamihardja A, Shi M, Epstein JE, Maiolatesi S, Tosh D, Limbach K, Angov E, Bergmann-Leitner E, Bruder JT, Doolan DL, King CR, Carucci D, Dutta S, Soisson L, Diggs C, Hollingdale MR, Ockenhouse CF, Richie TL.

PLoS One. 2013;8(2):e55571. doi: 10.1371/journal.pone.0055571. Epub 2013 Feb 14.

8.

Modification of Ad5 hexon hypervariable regions circumvents pre-existing Ad5 neutralizing antibodies and induces protective immune responses.

Bruder JT, Semenova E, Chen P, Limbach K, Patterson NB, Stefaniak ME, Konovalova S, Thomas C, Hamilton M, King CR, Richie TL, Doolan DL.

PLoS One. 2012;7(4):e33920. doi: 10.1371/journal.pone.0033920. Epub 2012 Apr 5. Erratum in: PLoS One. 2012;7(5): doi/10.1371/annotation/c110beed-3cac-48db-9039-ba4498d5db50.

9.

Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP component.

Tamminga C, Sedegah M, Regis D, Chuang I, Epstein JE, Spring M, Mendoza-Silveiras J, McGrath S, Maiolatesi S, Reyes S, Steinbeiss V, Fedders C, Smith K, House B, Ganeshan H, Lejano J, Abot E, Banania GJ, Sayo R, Farooq F, Belmonte M, Murphy J, Komisar J, Williams J, Shi M, Brambilla D, Manohar N, Richie NO, Wood C, Limbach K, Patterson NB, Bruder JT, Doolan DL, King CR, Diggs C, Soisson L, Carucci D, Levine G, Dutta S, Hollingdale MR, Ockenhouse CF, Richie TL.

PLoS One. 2011;6(10):e25868. doi: 10.1371/journal.pone.0025868. Epub 2011 Oct 7.

10.

Adenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adults.

Sedegah M, Tamminga C, McGrath S, House B, Ganeshan H, Lejano J, Abot E, Banania GJ, Sayo R, Farooq F, Belmonte M, Manohar N, Richie NO, Wood C, Long CA, Regis D, Williams FT, Shi M, Chuang I, Spring M, Epstein JE, Mendoza-Silveiras J, Limbach K, Patterson NB, Bruder JT, Doolan DL, King CR, Soisson L, Diggs C, Carucci D, Dutta S, Hollingdale MR, Ockenhouse CF, Richie TL.

PLoS One. 2011;6(10):e24586. doi: 10.1371/journal.pone.0024586. Epub 2011 Oct 7.

11.

Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein.

Sedegah M, Kim Y, Peters B, McGrath S, Ganeshan H, Lejano J, Abot E, Banania G, Belmonte M, Sayo R, Farooq F, Doolan DL, Regis D, Tamminga C, Chuang I, Bruder JT, King CR, Ockenhouse CF, Faber B, Remarque E, Hollingdale MR, Richie TL, Sette A.

Malar J. 2010 Aug 24;9:241. doi: 10.1186/1475-2875-9-241.

12.

Adenovectors induce functional antibodies capable of potent inhibition of blood stage malaria parasite growth.

Bruder JT, Stefaniak ME, Patterson NB, Chen P, Konovalova S, Limbach K, Campo JJ, Ettyreddy D, Li S, Dubovsky F, Richie TL, King CR, Long CA, Doolan DL.

Vaccine. 2010 Apr 19;28(18):3201-10. doi: 10.1016/j.vaccine.2010.02.024. Epub 2010 Feb 25.

PMID:
20188680
13.

Molecular vaccines for malaria.

Bruder JT, Angov E, Limbach KJ, Richie TL.

Hum Vaccin. 2010 Jan;6(1):54-77. Epub 2010 Jan 29. Review.

PMID:
20061792
14.

Sterile protection against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: comparison of heterologous prime boost strategies.

Jiang G, Shi M, Conteh S, Richie N, Banania G, Geneshan H, Valencia A, Singh P, Aguiar J, Limbach K, Kamrud KI, Rayner J, Smith J, Bruder JT, King CR, Tsuboi T, Takeo S, Endo Y, Doolan DL, Richie TL, Weiss WR.

PLoS One. 2009 Aug 10;4(8):e6559. doi: 10.1371/journal.pone.0006559.

15.

Persistent expression of PEDF in the eye using high-capacity adenovectors.

Chen P, Hamilton M, Thomas CA, Kroeger K, Carrion M, Macgill RS, Gehlbach P, Brough DE, Wei LL, King CR, Bruder JT.

Mol Ther. 2008 Dec;16(12):1986-94. doi: 10.1038/mt.2008.211. Epub 2008 Sep 30.

16.

Promoters influence the kinetics of transgene expression following adenovector gene delivery.

Chen P, Tian J, Kovesdi I, Bruder JT.

J Gene Med. 2008 Feb;10(2):123-31.

PMID:
18064718
17.

Epitopes expressed in different adenovirus capsid proteins induce different levels of epitope-specific immunity.

Krause A, Joh JH, Hackett NR, Roelvink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG, Worgall S.

J Virol. 2006 Jun;80(11):5523-30.

18.

Repeated administration of adenovector in the eye results in efficient gene delivery.

Hamilton MM, Brough DE, McVey D, Bruder JT, King CR, Wei LL.

Invest Ophthalmol Vis Sci. 2006 Jan;47(1):299-305.

PMID:
16384977
19.

Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid.

Worgall S, Krause A, Rivara M, Hee KK, Vintayen EV, Hackett NR, Roelvink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG.

J Clin Invest. 2005 May;115(5):1281-9. Epub 2005 Apr 1.

20.

Increased revascularization efficacy after administration of an adenovirus encoding VEGF(121).

Perrin LA, June JE, Rosebury W, Robertson A, Kovesdi I, Bruder JT, Kessler PD, Keiser JA, Gordon D.

Gene Ther. 2004 Mar;11(6):512-21.

PMID:
14999223
21.

Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responses.

Worgall S, Busch A, Rivara M, Bonnyay D, Leopold PL, Merritt R, Hackett NR, Rovelink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG.

J Virol. 2004 Mar;78(5):2572-80.

22.

The amyloid precursor-like protein 2 and the adenoviral E3/19K protein both bind to a conformational site on H-2Kd and regulate H-2Kd expression.

Morris CR, Petersen JL, Vargas SE, Turnquist HR, McIlhaney MM, Sanderson SD, Bruder JT, Yu YY, Burgert HG, Solheim JC.

J Biol Chem. 2003 Apr 11;278(15):12618-23. Epub 2002 Dec 27.

23.

Transduction and apoptosis induction in the rat prostate, using adenovirus vectors.

Kirkman W 3rd, Chen P, Schroeder R, Feneley MR, Rodriguez R, Wickham TJ, King CR, Bruder JT.

Hum Gene Ther. 2001 Aug 10;12(12):1499-512.

PMID:
11506693
24.

Ex vivo adenovirus mediated gene transfection of human conjunctival epithelium.

Shen J, Taylor N, Duncan L, Kovesdi I, Bruder JT, Forrester JV, Dick AD.

Br J Ophthalmol. 2001 Jul;85(7):861-7.

25.

Effective repeat administration with adenovirus vectors to the muscle.

Chen P, Kovesdi I, Bruder JT.

Gene Ther. 2000 Apr;7(7):587-95.

26.

Improved production of adenovirus vectors expressing apoptotic transgenes.

Bruder JT, Appiah A, Kirkman WM 3rd, Chen P, Tian J, Reddy D, Brough DE, Lizonova A, Kovesdi I.

Hum Gene Ther. 2000 Jan 1;11(1):139-49.

PMID:
10646646
27.

Regulation of endothelial cell adherens junctions by a Ras-dependent signal transduction pathway.

Hegland DD, Sullivan DM, Rovira II, Li A, Kovesdi I, Bruder JT, Finkel T.

Biochem Biophys Res Commun. 1999 Jul 5;260(2):371-6.

PMID:
10403777
28.

VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases.

Doanes AM, Hegland DD, Sethi R, Kovesdi I, Bruder JT, Finkel T.

Biochem Biophys Res Commun. 1999 Feb 16;255(2):545-8.

PMID:
10049745
29.

A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy.

Pracyk JB, Tanaka K, Hegland DD, Kim KS, Sethi R, Rovira II, Blazina DR, Lee L, Bruder JT, Kovesdi I, Goldshmidt-Clermont PJ, Irani K, Finkel T.

J Clin Invest. 1998 Sep 1;102(5):929-37.

30.

Protection from reoxygenation injury by inhibition of rac1.

Kim KS, Takeda K, Sethi R, Pracyk JB, Tanaka K, Zhou YF, Yu ZX, Ferrans VJ, Bruder JT, Kovesdi I, Irani K, Goldschmidt-Clermont P, Finkel T.

J Clin Invest. 1998 May 1;101(9):1821-6.

31.

Interaction of the adenovirus 14.7-kDa protein with FLICE inhibits Fas ligand-induced apoptosis.

Chen P, Tian J, Kovesdi I, Bruder JT.

J Biol Chem. 1998 Mar 6;273(10):5815-20.

32.

Adenoviral vectors for gene transfer.

Kovesdi I, Brough DE, Bruder JT, Wickham TJ.

Curr Opin Biotechnol. 1997 Oct;8(5):583-9. Review.

PMID:
9353227
33.
34.
35.
36.

The MEK kinase activity of the catalytic domain of RAF-1 is regulated independently of Ras binding in T cells.

Whitehurst CE, Owaki H, Bruder JT, Rapp UR, Geppert TD.

J Biol Chem. 1995 Mar 10;270(10):5594-9.

37.

Association of Raf with the CD3 delta and gamma chains of the T cell receptor-CD3 complex.

Loh C, Romeo C, Seed B, Bruder JT, Rapp U, Rao A.

J Biol Chem. 1994 Mar 25;269(12):8817-25.

38.
39.

Oncogene activation of HIV-LTR-driven expression via the NF-kappa B binding sites.

Bruder JT, Heidecker G, Tan TH, Weske JC, Derse D, Rapp UR.

Nucleic Acids Res. 1993 Nov 11;21(22):5229-34.

40.

Raf-1 is required for T cell IL2 production.

Owaki H, Varma R, Gillis B, Bruder JT, Rapp UR, Davis LS, Geppert TD.

EMBO J. 1993 Nov;12(11):4367-73.

41.

H-ras and raf-1 cooperate in transformation of NIH3T3 fibroblasts.

Cuadrado A, Bruder JT, Heidaran MA, App H, Rapp UR, Aaronson SA.

Oncogene. 1993 Sep;8(9):2443-8.

PMID:
8361757
42.

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1.

Zhang XF, Settleman J, Kyriakis JM, Takeuchi-Suzuki E, Elledge SJ, Marshall MS, Bruder JT, Rapp UR, Avruch J.

Nature. 1993 Jul 22;364(6435):308-13.

PMID:
8332187
43.

UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase.

Radler-Pohl A, Sachsenmaier C, Gebel S, Auer HP, Bruder JT, Rapp U, Angel P, Rahmsdorf HJ, Herrlich P.

EMBO J. 1993 Mar;12(3):1005-12.

44.

Different binding site requirements for binding and activation for the bipartite enhancer factor EF-1A.

Bolwig GM, Bruder JT, Hearing P.

Nucleic Acids Res. 1992 Dec 25;20(24):6555-64.

45.
46.

Evidence that Ha-Ras mediates two distinguishable intracellular signals activated by v-Src.

Qureshi SA, Alexandropoulos K, Rim M, Joseph CK, Bruder JT, Rapp UR, Foster DA.

J Biol Chem. 1992 Sep 5;267(25):17635-9.

47.

Ras controls coupling of growth factor receptors and protein kinase C in the membrane to Raf-1 and B-Raf protein serine kinases in the cytosol.

Troppmair J, Bruder JT, App H, Cai H, Liptak L, Szeberényi J, Cooper GM, Rapp UR.

Oncogene. 1992 Sep;7(9):1867-73.

PMID:
1386920
48.

Supplemental Content

Loading ...
Support Center