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Items: 1 to 50 of 108

1.

Plasma Protein and Lipoprotein Binding of Cis- and Trans-Permethrin and Deltamethrin in Adult Humans and Rats.

Sethi P, Bruckner JV, Mortuza TB, Cummings BS, Muralidhara S, White CA.

Drug Metab Dispos. 2019 Sep;47(9):941-948. doi: 10.1124/dmd.118.085464. Epub 2019 Jun 27.

PMID:
31248885
2.

Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo Extrapolation.

Song G, Moreau M, Efremenko A, Lake BG, Wu H, Bruckner JV, White CA, Osimitz TG, Creek MR, Hinderliter PM, Clewell HJ, Yoon M.

Toxicol Sci. 2019 Jun 1;169(2):365-379. doi: 10.1093/toxsci/kfz042.

PMID:
30768128
3.

Age Dependency of Blood-Brain Barrier Penetration by cis- and trans-Permethrin in the Rat.

Mortuza TB, Edwards GL, White CA, Patel V, Cummings BS, Bruckner JV.

Drug Metab Dispos. 2019 Mar;47(3):234-237. doi: 10.1124/dmd.118.084822. Epub 2018 Dec 6.

PMID:
30523003
4.

Effect of dose and exposure protocol on the toxicokinetics and first-pass elimination of trichloroethylene and 1,1,1-trichloroethane.

Mortuza T, Muralidhara S, White CA, Cummings BS, Hines C, Bruckner JV.

Toxicol Appl Pharmacol. 2018 Dec 1;360:185-192. doi: 10.1016/j.taap.2018.09.043. Epub 2018 Oct 1.

PMID:
30287391
5.

Toxicokinetics of Deltamethrin: Dosage Dependency, Vehicle Effects, and Low-Dose Age-Equivalent Dosimetry in Rats.

Mortuza T, Chen C, White CA, Cummings BS, Muralidhara S, Gullick D, Bruckner JV.

Toxicol Sci. 2018 Mar 1;162(1):327-336. doi: 10.1093/toxsci/kfx260.

PMID:
29165640
6.

Gas chromatography/negative chemical ionization mass spectrometry of transfluthrin in rat plasma and brain.

Hooshfar S, Mortuza TB, Rogers CA, Linzey MR, Gullick DR, Bruckner JV, White CA, Bartlett MG.

Rapid Commun Mass Spectrom. 2017 Oct 15;31(19):1573-1581. doi: 10.1002/rcm.7942.

PMID:
28708331
7.

Simultaneous determination of cis-permethrin and trans-permethrin in rat plasma and brain tissue using gas chromatography-negative chemical ionization mass spectrometry.

Hooshfar S, Gullick DR, Linzey MR, Mortuza T, Abdel Rahman MH, Rogers CA, Bruckner JV, White CA, Bartlett MG.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Aug 15;1060:291-299. doi: 10.1016/j.jchromb.2017.06.019. Epub 2017 Jun 13.

PMID:
28651172
8.

Brain uptake of deltamethrin in rats as a function of plasma protein binding and blood-brain barrier maturation.

Amaraneni M, Pang J, Mortuza TB, Muralidhara S, Cummings BS, White CA, Vorhees CV, Zastre J, Bruckner JV.

Neurotoxicology. 2017 Sep;62:24-29. doi: 10.1016/j.neuro.2017.04.009. Epub 2017 May 8.

PMID:
28495520
9.

Influence of Maturation on In Vivo Tissue to Plasma Partition Coefficients for Cis- and Trans-Permethrin.

Amaraneni M, Pang J, Bruckner JV, Muralidhara S, Mortuza TB, Gullick D, Hooshfar S, White CA, Cummings BS.

J Pharm Sci. 2017 Aug;106(8):2144-2151. doi: 10.1016/j.xphs.2017.04.024. Epub 2017 Apr 23.

PMID:
28445697
10.

The immature rat as a potential model for chemical risks to children: Ontogeny of selected hepatic P450s.

McPhail BT, White CA, Cummings BS, Muralidhara S, Wilson JT, Bruckner JV.

Chem Biol Interact. 2016 Aug 25;256:167-77. doi: 10.1016/j.cbi.2016.07.005. Epub 2016 Jul 5.

PMID:
27387539
11.

Plasma protein binding limits the blood brain barrier permeation of the pyrethroid insecticide, deltamethrin.

Amaraneni M, Sharma A, Pang J, Muralidhara S, Cummings BS, White CA, Bruckner JV, Zastre J.

Toxicol Lett. 2016 May 27;250-251:21-8. doi: 10.1016/j.toxlet.2016.03.006. Epub 2016 Mar 22.

PMID:
27016408
12.

Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin.

Sethi PK, White CA, Cummings BS, Hines RN, Muralidhara S, Bruckner JV.

Pediatr Res. 2016 Mar;79(3):409-15. doi: 10.1038/pr.2015.237. Epub 2015 Nov 16.

PMID:
26571224
13.

Measurement of plasma protein and lipoprotein binding of pyrethroids.

Sethi PK, Muralidhara S, Bruckner JV, White CA.

J Pharmacol Toxicol Methods. 2014 Jul-Aug;70(1):106-11. doi: 10.1016/j.vascn.2014.06.002. Epub 2014 Jun 11.

PMID:
24929057
14.

Determination of deltamethrin in rat plasma and brain using gas chromatography-negative chemical ionization mass spectrometry.

Gullick D, Popovici A, Young HC, Bruckner JV, Cummings BS, Li P, Bartlett MG.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 1;960:158-65. doi: 10.1016/j.jchromb.2014.04.008. Epub 2014 Apr 13.

PMID:
24814001
15.

Age, dose, and time-dependency of plasma and tissue distribution of deltamethrin in immature rats.

Kim KB, Anand SS, Kim HJ, White CA, Fisher JW, Tornero-Velez R, Bruckner JV.

Toxicol Sci. 2010 Jun;115(2):354-68. doi: 10.1093/toxsci/kfq074. Epub 2010 Mar 8.

PMID:
20211939
16.

Influence of exposure route and oral dosage regimen on 1, 1-dichloroethylene toxicokinetics and target organ toxicity.

Bruckner JV, White CA, Muralidhara S, Hines C, Dallas CE.

J Pharmacol Exp Ther. 2010 May;333(2):519-27. doi: 10.1124/jpet.109.162479. Epub 2010 Feb 3.

PMID:
20130112
17.

Evaluation of deltamethrin kinetics and dosimetry in the maturing rat using a PBPK model.

Tornero-Velez R, Mirfazaelian A, Kim KB, Anand SS, Kim HJ, Haines WT, Bruckner JV, Fisher JW.

Toxicol Appl Pharmacol. 2010 Apr 15;244(2):208-17. doi: 10.1016/j.taap.2009.12.034. Epub 2010 Jan 4.

PMID:
20045431
18.

Bayesian analysis of a physiologically based pharmacokinetic model for perchloroethylene in humans.

Qiu J, Chien YC, Bruckner JV, Fisher JW.

J Toxicol Environ Health A. 2010;73(1):74-91. doi: 10.1080/15287390903249099.

PMID:
19953421
19.

Trichloroethylene risk assessment: a review and commentary.

Jollow DJ, Bruckner JV, McMillan DC, Fisher JW, Hoel DG, Mohr LC.

Crit Rev Toxicol. 2009;39(9):782-97. doi: 10.3109/10408440903222177. Review.

PMID:
19852561
20.

Presystemic elimination of trichloroethylene in rats following environmentally relevant oral exposures.

Liu Y, Bartlett MG, White CA, Muralidhara S, Bruckner JV.

Drug Metab Dispos. 2009 Oct;37(10):1994-8. doi: 10.1124/dmd.109.028100. Epub 2009 Jul 6.

PMID:
19581386
21.

Determination of trichloroethylene from adipose tissue by headspace solid-phase microextraction gas chromatography/mass spectrometry.

Liu Y, Muralidhara S, Bruckner JV, Bartlett MG.

Rapid Commun Mass Spectrom. 2009 Feb;23(3):455-8. doi: 10.1002/rcm.3891. No abstract available.

PMID:
19127549
22.
23.
24.

Trace level determination of trichloroethylene in biological samples by headspace solid-phase microextraction gas chromatography/negative chemical ionization mass spectrometry.

Liu Y, Muralidhara S, Bruckner JV, Bartlett MG.

Rapid Commun Mass Spectrom. 2008;22(6):797-806. doi: 10.1002/rcm.3426.

PMID:
18278820
25.

Determination of trichloroethylene in biological samples by headspace solid-phase microextraction gas chromatography/mass spectrometry.

Liu Y, Muralidhara S, Bruckner JV, Bartlett MG.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Feb 15;863(1):26-35. doi: 10.1016/j.jchromb.2007.12.010. Epub 2007 Dec 24.

PMID:
18249161
26.

Toxicokinetics and tissue distribution of deltamethrin in adult Sprague-Dawley rats.

Kim KB, Anand SS, Kim HJ, White CA, Bruckner JV.

Toxicol Sci. 2008 Feb;101(2):197-205. Epub 2007 Dec 3.

PMID:
18056584
27.

Organ growth functions in maturing male Sprague-Dawley rats.

Mirfazaelian A, Kim KB, Lee S, Kim HJ, Bruckner JV, Fisher JW.

J Toxicol Environ Health A. 2007 Mar 1;70(5):429-38.

PMID:
17454567
28.

Formulation-dependent toxicokinetics explains differences in the GI absorption, bioavailability and acute neurotoxicity of deltamethrin in rats.

Kim KB, Anand SS, Muralidhara S, Kim HJ, Bruckner JV.

Toxicology. 2007 May 20;234(3):194-202. Epub 2007 Feb 28.

PMID:
17448586
29.

Development of a physiologically based pharmacokinetic model for deltamethrin in the adult male Sprague-Dawley rat.

Mirfazaelian A, Kim KB, Anand SS, Kim HJ, Tornero-Velez R, Bruckner JV, Fisher JW.

Toxicol Sci. 2006 Oct;93(2):432-42. Epub 2006 Jul 10.

PMID:
16831841
30.

Rapid determination of the synthetic pyrethroid insecticide, deltamethrin, in rat plasma and tissues by HPLC.

Kim KB, Bartlett MG, Anand SS, Bruckner JV, Kim HJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Apr 13;834(1-2):141-8. Epub 2006 Mar 22.

PMID:
16554192
31.

Effect of PCB 126 on hepatic metabolism of thyroxine and perturbations in the hypothalamic-pituitary-thyroid axis in the rat.

Fisher JW, Campbell J, Muralidhara S, Bruckner JV, Ferguson D, Mumtaz M, Harmon B, Hedge JM, Crofton KM, Kim H, Almekinder TL.

Toxicol Sci. 2006 Mar;90(1):87-95. Epub 2005 Dec 9.

PMID:
16339789
32.

Ontogeny of hepatic and plasma metabolism of deltamethrin in vitro: role in age-dependent acute neurotoxicity.

Anand SS, Kim KB, Padilla S, Muralidhara S, Kim HJ, Fisher JW, Bruckner JV.

Drug Metab Dispos. 2006 Mar;34(3):389-97. Epub 2005 Dec 2.

PMID:
16326812
33.

Characterization of deltamethrin metabolism by rat plasma and liver microsomes.

Anand SS, Bruckner JV, Haines WT, Muralidhara S, Fisher JW, Padilla S.

Toxicol Appl Pharmacol. 2006 Apr 15;212(2):156-66. Epub 2005 Sep 16.

PMID:
16169030
34.

The potential adverse health effects of dental amalgam.

Brownawell AM, Berent S, Brent RL, Bruckner JV, Doull J, Gershwin EM, Hood RD, Matanoski GM, Rubin R, Weiss B, Karol MH.

Toxicol Rev. 2005;24(1):1-10. Review.

PMID:
16042501
35.
36.

Analysis of dichloroacetic acid in rat blood and tissues by hydrophilic interaction liquid chromatography with tandem mass spectrometry.

Delinsky AD, Delinsky DC, Muralidhara S, Fisher JW, Bruckner JV, Bartlett MG.

Rapid Commun Mass Spectrom. 2005;19(8):1075-83.

PMID:
15776496
37.

Determination of deltamethrin and its metabolite 3-phenoxybenzoic acid in male rat plasma by high-performance liquid chromatography.

Ding Y, White CA, Muralidhara S, Bruckner JV, Bartlett MG.

J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Oct 25;810(2):221-7.

PMID:
15380718
38.

The Acute Exposure Guideline Level (AEGL) program: applications of physiologically based pharmacokinetic modeling.

Bruckner JV, Keys DA, Fisher JW.

J Toxicol Environ Health A. 2004 Apr 23-May 28;67(8-10):621-34. Review.

PMID:
15192858
39.

PBPK modeling of the metabolic interactions of carbon tetrachloride and tetrachloroethylene in B6C3F1 mice.

Fisher J, Lumpkin M, Boyd J, Mahle D, Bruckner JV, El-Masri HA.

Environ Toxicol Pharmacol. 2004 Mar;16(1-2):93-105. doi: 10.1016/j.etap.2003.10.006.

PMID:
21782696
40.

Plasma binding of trichloroacetic acid in mice, rats, and humans under cancer bioassay and environmental exposure conditions.

Lumpkin MH, Bruckner JV, Campbell JL, Dallas CE, White CA, Fisher JW.

Drug Metab Dispos. 2003 Oct;31(10):1203-7.

PMID:
12975328
41.

Tissue dosimetry expansion and cross-validation of rat and mouse physiologically based pharmacokinetic models for trichloroethylene.

Keys DA, Bruckner JV, Muralidhara S, Fisher JW.

Toxicol Sci. 2003 Nov;76(1):35-50. Epub 2003 Aug 12.

PMID:
12915716
42.

Trace level determination of trichloroethylene from liver, lung and kidney tissues by gas chromatography-magnetic sector mass spectrometry.

Brown SD, Muralidhara S, Bruckner JV, Bartlett MG.

J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jan 15;783(2):319-25.

PMID:
12482474
43.

Mechanisms of circadian rhythmicity of carbon tetrachloride hepatotoxicity.

Bruckner JV, Ramanathan R, Lee KM, Muralidhara S.

J Pharmacol Exp Ther. 2002 Jan;300(1):273-81.

PMID:
11752126
44.

Comments on "Children's health, susceptibility, and regulatory approaches to reducing risk from chemical carcinogens".

Landrigan PJ, Mattison DR, Boardman B, Bruckner JV, Jackson RJ, Karol MH, Krewski D, Weil WB.

Environ Health Perspect. 2001 Sep;109(9):A412-3. No abstract available.

45.

Acute, subacute, and subchronic oral toxicity studies of 1,1-dichloroethane in rats: application to risk evaluation.

Muralidhara S, Ramanathan R, Mehta SM, Lash LH, Acosta D, Bruckner JV.

Toxicol Sci. 2001 Nov;64(1):135-45.

PMID:
11606809
46.

Acute, short-term, and subchronic oral toxicity of 1,1,1-trichloroethane in rats.

Bruckner JV, Kyle GM, Luthra R, Acosta D, Mehta SM, Sethuraman S, Muralidhara S.

Toxicol Sci. 2001 Apr;60(2):363-72.

PMID:
11248149
47.

Differences in sensitivity of children and adults to chemical toxicity: the NAS panel report.

Bruckner JV.

Regul Toxicol Pharmacol. 2000 Jun;31(3):280-5.

PMID:
10915586
48.

Mechanisms of the dose-dependent kinetics of trichloroethylene: oral bolus dosing of rats.

Lee KM, Muralidhara S, White CA, Bruckner JV.

Toxicol Appl Pharmacol. 2000 Apr 1;164(1):55-64.

PMID:
10739744
49.

Contribution of direct solvent injury to the dose-dependent kinetics of trichloroethylene: portal vein administration to rats.

Lee KM, Muralidhara S, Schnellmann RG, Bruckner JV.

Toxicol Appl Pharmacol. 2000 Apr 1;164(1):46-54.

PMID:
10739743
50.

Simple method for rapid measurement of trichloroethylene and its major metabolites in biological samples.

Muralidhara S, Bruckner JV.

J Chromatogr B Biomed Sci Appl. 1999 Sep 10;732(1):145-53.

PMID:
10517231

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