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Items: 1 to 50 of 55

1.

Biphasic Effect of Sildenafil on Energy Sensing is Mediated by Phosphodiesterases 2 and 3 in Adipocytes and Hepatocytes.

Banerjee J, Bruckbauer A, Thorpe T, Zemel MB.

Int J Mol Sci. 2019 Jun 19;20(12). pii: E2992. doi: 10.3390/ijms20122992.

2.

Dynamic reorganisation of intermediate filaments coordinates early B-cell activation.

Tsui C, Maldonado P, Montaner B, Borroto A, Alarcon B, Bruckbauer A, Martinez-Martin N, Batista FD.

Life Sci Alliance. 2018 Aug 20;1(5):e201800060. doi: 10.26508/lsa.201800060. eCollection 2018 Oct.

3.

The Lack of WIP Binding to Actin Results in Impaired B Cell Migration and Altered Humoral Immune Responses.

Keppler SJ, Burbage M, Gasparrini F, Hartjes L, Aggarwal S, Massaad MJ, Geha RS, Bruckbauer A, Batista FD.

Cell Rep. 2018 Jul 17;24(3):619-629. doi: 10.1016/j.celrep.2018.06.051.

4.

Protein Kinase C-β Dictates B Cell Fate by Regulating Mitochondrial Remodeling, Metabolic Reprogramming, and Heme Biosynthesis.

Tsui C, Martinez-Martin N, Gaya M, Maldonado P, Llorian M, Legrave NM, Rossi M, MacRae JI, Cameron AJ, Parker PJ, Leitges M, Bruckbauer A, Batista FD.

Immunity. 2018 Jun 19;48(6):1144-1159.e5. doi: 10.1016/j.immuni.2018.04.031. Epub 2018 Jun 5.

5.

Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity.

Burbage M, Gasparrini F, Aggarwal S, Gaya M, Arnold J, Nair U, Way M, Bruckbauer A, Batista FD.

Elife. 2018 Jan 16;7. pii: e26556. doi: 10.7554/eLife.26556.

6.

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.

Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, Aid M, Tsui C, Maldonado P, Nair U, Ghneim K, Fallon PG, Sekaly RP, Barouch DH, Shalek AK, Bruckbauer A, Strid J, Batista FD.

Cell. 2018 Jan 25;172(3):517-533.e20. doi: 10.1016/j.cell.2017.11.036. Epub 2017 Dec 14.

7.

Erratum: Leucine-nicotinic acid synergy stimulates AMPK/Sirt1 signaling and regulates lipid metabolism and lifespan in Caenorhabditis elegans, and hyperlipidemia and atherosclerosis in mice.

Bruckbauer A, Banerjee J, Cao Q, Cui X, Jing J, Zha L, Li F, Xue B, Shi H, Zemel MB.

Am J Cardiovasc Dis. 2017 Jul 25;7(4):97. eCollection 2017.

8.

Leucine-nicotinic acid synergy stimulates AMPK/Sirt1 signaling and regulates lipid metabolism and lifespan in Caenorhabditis elegans, and hyperlipidemia and atherosclerosis in mice.

Bruckbauer A, Banerjee J, Cao Q, Cui X, Jing J, Zha L, Li F, Xue B, Shi H, Zemel MB.

Am J Cardiovasc Dis. 2017 Apr 15;7(2):33-47. eCollection 2017. Erratum in: Am J Cardiovasc Dis. 2017 Jul 25;7(4):97.

9.

A switch from canonical to noncanonical autophagy shapes B cell responses.

Martinez-Martin N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, Tsui C, Burbage M, Keppler SJ, Montaner B, Jefferies HB, Nair U, Zhao YG, Domart MC, Collinson L, Bruckbauer A, Tooze SA, Batista FD.

Science. 2017 Feb 10;355(6325):641-647. doi: 10.1126/science.aal3908.

10.

A Combination of Leucine, Metformin, and Sildenafil Treats Nonalcoholic Fatty Liver Disease and Steatohepatitis in Mice.

Bruckbauer A, Banerjee J, Fu L, Li F, Cao Q, Cui X, Wu R, Shi H, Xue B, Zemel MB.

Int J Hepatol. 2016;2016:9185987. doi: 10.1155/2016/9185987. Epub 2016 Nov 30.

11.
12.

Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts.

Calvo F, Ranftl R, Hooper S, Farrugia AJ, Moeendarbary E, Bruckbauer A, Batista F, Charras G, Sahai E.

Cell Rep. 2015 Dec 29;13(12):2699-714. doi: 10.1016/j.celrep.2015.11.052. Epub 2015 Dec 17.

13.

Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling.

Gasparrini F, Feest C, Bruckbauer A, Mattila PK, Müller J, Nitschke L, Bray D, Batista FD.

EMBO J. 2016 Feb 1;35(3):258-80. doi: 10.15252/embj.201593027. Epub 2015 Dec 15.

14.

Subtilase contributes to the cytotoxicity of a Shiga toxin-producing Escherichia coli strain encoding three different toxins.

Hauser E, Bruederle M, Reich C, Bruckbauer A, Funk J, Schmidt H.

Int J Food Microbiol. 2016 Jan 18;217:156-61. doi: 10.1016/j.ijfoodmicro.2015.10.023. Epub 2015 Oct 25.

PMID:
26523884
15.

Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells.

Keppler SJ, Gasparrini F, Burbage M, Aggarwal S, Frederico B, Geha RS, Way M, Bruckbauer A, Batista FD.

Immunity. 2015 Oct 20;43(4):660-73. doi: 10.1016/j.immuni.2015.09.004. Epub 2015 Oct 6.

16.

Interaction between metformin and leucine in reducing hyperlipidemia and hepatic lipid accumulation in diet-induced obese mice.

Fu L, Bruckbauer A, Li F, Cao Q, Cui X, Wu R, Shi H, Zemel MB, Xue B.

Metabolism. 2015 Nov;64(11):1426-34. doi: 10.1016/j.metabol.2015.07.006. Epub 2015 Jul 17.

PMID:
26303871
17.

Interaction between leucine and phosphodiesterase 5 inhibition in modulating insulin sensitivity and lipid metabolism.

Fu L, Li F, Bruckbauer A, Cao Q, Cui X, Wu R, Shi H, Xue B, Zemel MB.

Diabetes Metab Syndr Obes. 2015 May 6;8:227-39. doi: 10.2147/DMSO.S82338. eCollection 2015.

18.

Leucine amplifies the effects of metformin on insulin sensitivity and glycemic control in diet-induced obese mice.

Fu L, Bruckbauer A, Li F, Cao Q, Cui X, Wu R, Shi H, Zemel MB, Xue B.

Metabolism. 2015 Jul;64(7):845-56. doi: 10.1016/j.metabol.2015.03.007. Epub 2015 Mar 19.

PMID:
25858853
19.

Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection.

Gaya M, Castello A, Montaner B, Rogers N, Reis e Sousa C, Bruckbauer A, Batista FD.

Science. 2015 Feb 6;347(6222):667-72. doi: 10.1126/science.aaa1300.

20.

Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity.

Burbage M, Keppler SJ, Gasparrini F, Martínez-Martín N, Gaya M, Feest C, Domart MC, Brakebusch C, Collinson L, Bruckbauer A, Batista FD.

J Exp Med. 2015 Jan 12;212(1):53-72. doi: 10.1084/jem.20141143. Epub 2014 Dec 29.

21.

STRIPAK components determine mode of cancer cell migration and metastasis.

Madsen CD, Hooper S, Tozluoglu M, Bruckbauer A, Fletcher G, Erler JT, Bates PA, Thompson B, Sahai E.

Nat Cell Biol. 2015 Jan;17(1):68-80. doi: 10.1038/ncb3083. Epub 2014 Dec 22.

22.

Synergistic effects of polyphenols and methylxanthines with Leucine on AMPK/Sirtuin-mediated metabolism in muscle cells and adipocytes.

Bruckbauer A, Zemel MB.

PLoS One. 2014 Feb 14;9(2):e89166. doi: 10.1371/journal.pone.0089166. eCollection 2014.

23.

Effects of a leucine and pyridoxine-containing nutraceutical on body weight and composition in obese subjects.

Zemel MB, Bruckbauer A.

Diabetes Metab Syndr Obes. 2013 Aug 23;6:309-15. doi: 10.2147/DMSO.S49623. eCollection 2013.

24.

Dynamics and stoichiometry of a regulated enhancer-binding protein in live Escherichia coli cells.

Mehta P, Jovanovic G, Lenn T, Bruckbauer A, Engl C, Ying L, Buck M.

Nat Commun. 2013;4:1997. doi: 10.1038/ncomms2997.

25.

The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling.

Mattila PK, Feest C, Depoil D, Treanor B, Montaner B, Otipoby KL, Carter R, Justement LB, Bruckbauer A, Batista FD.

Immunity. 2013 Mar 21;38(3):461-74. doi: 10.1016/j.immuni.2012.11.019. Epub 2013 Mar 14.

26.

Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity.

Bruckbauer A, Zemel MB.

Diabetes Metab Syndr Obes. 2013;6:93-102. doi: 10.2147/DMSO.S40840. Epub 2013 Feb 13.

27.

Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice.

Bruckbauer A, Zemel MB, Thorpe T, Akula MR, Stuckey AC, Osborne D, Martin EB, Kennel S, Wall JS.

Nutr Metab (Lond). 2012 Aug 22;9(1):77. doi: 10.1186/1743-7075-9-77.

28.
29.

Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity.

Thaunat O, Granja AG, Barral P, Filby A, Montaner B, Collinson L, Martinez-Martin N, Harwood NE, Bruckbauer A, Batista FD.

Science. 2012 Jan 27;335(6067):475-9. doi: 10.1126/science.1214100.

30.

Effects of dairy consumption on SIRT1 and mitochondrial biogenesis in adipocytes and muscle cells.

Bruckbauer A, Zemel MB.

Nutr Metab (Lond). 2011 Dec 20;8:91. doi: 10.1186/1743-7075-8-91.

31.

B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster.

Schnyder T, Castello A, Feest C, Harwood NE, Oellerich T, Urlaub H, Engelke M, Wienands J, Bruckbauer A, Batista FD.

Immunity. 2011 Jun 24;34(6):905-18. doi: 10.1016/j.immuni.2011.06.001.

32.

Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity.

Treanor B, Depoil D, Bruckbauer A, Batista FD.

J Exp Med. 2011 May 9;208(5):1055-68. doi: 10.1084/jem.20101125. Epub 2011 Apr 11.

33.

Selective diffusion barriers separate membrane compartments.

Bruckbauer A, Dunne PD, James P, Howes E, Zhou D, Jones R, Klenerman D.

Biophys J. 2010 Jul 7;99(1):L1-3. doi: 10.1016/j.bpj.2010.03.067.

34.

CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes.

Barral P, Polzella P, Bruckbauer A, van Rooijen N, Besra GS, Cerundolo V, Batista FD.

Nat Immunol. 2010 Apr;11(4):303-12. doi: 10.1038/ni.1853. Epub 2010 Mar 14.

35.

The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor.

Treanor B, Depoil D, Gonzalez-Granja A, Barral P, Weber M, Dushek O, Bruckbauer A, Batista FD.

Immunity. 2010 Feb 26;32(2):187-99. doi: 10.1016/j.immuni.2009.12.005. Epub 2010 Feb 18.

36.

Tracking diffusion of GM1 gangliosides and zona pellucida binding molecules in sperm plasma membranes following cholesterol efflux.

Jones R, Howes E, Dunne PD, James P, Bruckbauer A, Klenerman D.

Dev Biol. 2010 Mar 15;339(2):398-406. doi: 10.1016/j.ydbio.2009.12.044. Epub 2010 Jan 7.

37.

The effects of dairy components on energy partitioning and metabolic risk in mice: a microarray study.

Bruckbauer A, Gouffon J, Rekapalli B, Zemel MB.

J Nutrigenet Nutrigenomics. 2009;2(2):64-77. doi: 10.1159/000205936. Epub 2009 Mar 4.

PMID:
19690433
38.

Dietary calcium and dairy modulation of oxidative stress and mortality in aP2-agouti and wild-type mice.

Bruckbauer A, Zemel MB.

Nutrients. 2009 Jan;1(1):50-70. doi: 10.3390/nu1010050. Epub 2009 Aug 14.

39.

Bayesian inference for improved single molecule fluorescence tracking.

Yoon JW, Bruckbauer A, Fitzgerald WJ, Klenerman D.

Biophys J. 2008 Jun;94(12):4932-47. doi: 10.1529/biophysj.107.116285. Epub 2008 Mar 13.

40.

Nanopipette delivery of individual molecules to cellular compartments for single-molecule fluorescence tracking.

Bruckbauer A, James P, Zhou D, Yoon JW, Excell D, Korchev Y, Jones R, Klenerman D.

Biophys J. 2007 Nov 1;93(9):3120-31. Epub 2007 Jul 13.

41.

Supramolecular organization of the sperm plasma membrane during maturation and capacitation.

Jones R, James PS, Howes L, Bruckbauer A, Klenerman D.

Asian J Androl. 2007 Jul;9(4):438-44. Review.

42.

Comment on "trapping single molecules by dielectrophoresis".

Ying L, Zhou D, Bruckbauer A.

Phys Rev Lett. 2006 May 19;96(19):199801; author reply 199802. Epub 2006 May 19. No abstract available.

PMID:
16803153
43.

Macroscopic 2D networks self-assembled from nanometer-sized protein/DNA complexes.

Manzanera M, Frankel DJ, Li H, Zhou D, Bruckbauer A, Kreutzmann P, Blackburn JM, Abell C, Rayment T, Klenerman D, Barker PD.

Nano Lett. 2006 Mar;6(3):365-70.

PMID:
16522024
44.

A reversible pH-driven DNA nanoswitch array.

Liu D, Bruckbauer A, Abell C, Balasubramanian S, Kang DJ, Klenerman D, Zhou D.

J Am Chem Soc. 2006 Feb 15;128(6):2067-71.

PMID:
16464109
45.

Nanoscale pipetting for controlled chemistry in small arrayed water droplets using a double-barrel pipet.

Rodolfa KT, Bruckbauer A, Zhou D, Schevchuk AI, Korchev YE, Klenerman D.

Nano Lett. 2006 Feb;6(2):252-7.

PMID:
16464045
46.

Two-component graded deposition of biomolecules with a double-barreled nanopipette.

Rodolfa KT, Bruckbauer A, Zhou D, Korchev YE, Klenerman D.

Angew Chem Int Ed Engl. 2005 Oct 28;44(42):6854-9. No abstract available.

PMID:
16249993
47.

The scanned nanopipette: a new tool for high resolution bioimaging and controlled deposition of biomolecules.

Ying L, Bruckbauer A, Zhou D, Gorelik J, Shevchuk A, Lab M, Korchev Y, Klenerman D.

Phys Chem Chem Phys. 2005 Aug 7;7(15):2859-66. Epub 2005 Jul 5.

PMID:
16189604
48.
49.

An addressable antibody nanoarray produced on a nanostructured surface.

Bruckbauer A, Zhou D, Kang DJ, Korchev YE, Abell C, Klenerman D.

J Am Chem Soc. 2004 Jun 2;126(21):6508-9.

PMID:
15161251
50.

Frequency and voltage dependence of the dielectrophoretic trapping of short lengths of DNA and dCTP in a nanopipette.

Ying L, White SS, Bruckbauer A, Meadows L, Korchev YE, Klenerman D.

Biophys J. 2004 Feb;86(2):1018-27.

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