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Items: 1 to 50 of 82

1.

ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice.

Jones FE, Bailey MA, Murray LS, Lu Y, McNeilly S, Schlötzer-Schrehardt U, Lennon R, Sado Y, Brownstein DG, Mullins JJ, Kadler KE, Van Agtmael T.

Dis Model Mech. 2016 Feb;9(2):165-76. doi: 10.1242/dmm.021741.

2.

Glucocorticoid receptor is required for foetal heart maturation.

Rog-Zielinska EA, Thomson A, Kenyon CJ, Brownstein DG, Moran CM, Szumska D, Michailidou Z, Richardson J, Owen E, Watt A, Morrison H, Forrester LM, Bhattacharya S, Holmes MC, Chapman KE.

Hum Mol Genet. 2013 Aug 15;22(16):3269-82. doi: 10.1093/hmg/ddt182. Epub 2013 Apr 16.

PMID:
23595884
3.

Mast cells express 11β-hydroxysteroid dehydrogenase type 1: a role in restraining mast cell degranulation.

Coutinho AE, Brown JK, Yang F, Brownstein DG, Gray M, Seckl JR, Savill JS, Chapman KE.

PLoS One. 2013;8(1):e54640. doi: 10.1371/journal.pone.0054640. Epub 2013 Jan 18.

4.

11β-Hydroxysteroid dehydrogenase type 1, but not type 2, deficiency worsens acute inflammation and experimental arthritis in mice.

Coutinho AE, Gray M, Brownstein DG, Salter DM, Sawatzky DA, Clay S, Gilmour JS, Seckl JR, Savill JS, Chapman KE.

Endocrinology. 2012 Jan;153(1):234-40. doi: 10.1210/en.2011-1398. Epub 2011 Nov 8.

5.

Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet.

Jamieson PM, Cleasby ME, Kuperman Y, Morton NM, Kelly PA, Brownstein DG, Mustard KJ, Vaughan JM, Carter RN, Hahn CN, Hardie DG, Seckl JR, Chen A, Vale WW.

Diabetologia. 2011 Sep;54(9):2392-403. doi: 10.1007/s00125-011-2205-6. Epub 2011 Jun 11.

6.

11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice.

Deuchar GA, McLean D, Hadoke PWF, Brownstein DG, Webb DJ, Mullins JJ, Chapman K, Seckl JR, Kotelevtsev YV.

Endocrinology. 2011 Jan;152(1):236-246. doi: 10.1210/en.2010-0925. Epub 2010 Nov 24.

7.

Expression of urocortin peptides in canine myocardium and plasma.

Veloso GF, Ohad DG, Francis AJ, Vaughan JM, Brownstein DG, Culshaw GJ, Vale WW, French AT, Jamieson PM.

Vet J. 2011 Jun;188(3):318-24. doi: 10.1016/j.tvjl.2010.05.019. Epub 2010 Jun 15.

8.

Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease.

Selfridge J, Song L, Brownstein DG, Melton DW.

DNA Repair (Amst). 2010 Jun 4;9(6):653-60. doi: 10.1016/j.dnarep.2010.02.018. Epub 2010 Apr 1.

PMID:
20362516
9.

Col4a1 mutation in mice causes defects in vascular function and low blood pressure associated with reduced red blood cell volume.

Van Agtmael T, Bailey MA, Schlötzer-Schrehardt U, Craigie E, Jackson IJ, Brownstein DG, Megson IL, Mullins JJ.

Hum Mol Genet. 2010 Mar 15;19(6):1119-28. doi: 10.1093/hmg/ddp584. Epub 2010 Jan 7.

10.

Expression of the neuroprotective slow Wallerian degeneration (WldS) gene in non-neuronal tissues.

Wishart TM, Brownstein DG, Thomson D, Tabakova AM, Boothe KM, Tsao JW, Gillingwater TH.

BMC Neurosci. 2009 Dec 16;10:148. doi: 10.1186/1471-2202-10-148.

11.

Topical thymidine dinucleotide application protects against UVB-induced skin cancer in mice with DNA repair gene (Ercc1)-deficient skin.

Lawrence NJ, Song L, Doig J, Ritchie AM, Brownstein DG, Melton DW.

DNA Repair (Amst). 2009 May 1;8(5):664-71. doi: 10.1016/j.dnarep.2009.01.020. Epub 2009 Mar 4.

PMID:
19264557
12.

Real-time visualization of human prolactin alternate promoter usage in vivo using a double-transgenic rat model.

Semprini S, Friedrichsen S, Harper CV, McNeilly JR, Adamson AD, Spiller DG, Kotelevtseva N, Brooker G, Brownstein DG, McNeilly AS, White MR, Davis JR, Mullins JJ.

Mol Endocrinol. 2009 Apr;23(4):529-38. doi: 10.1210/me.2008-0399. Epub 2009 Jan 15.

13.

Cyp11b1 null mouse, a model of congenital adrenal hyperplasia.

Mullins LJ, Peter A, Wrobel N, McNeilly JR, McNeilly AS, Al-Dujaili EA, Brownstein DG, Mullins JJ, Kenyon CJ.

J Biol Chem. 2009 Feb 6;284(6):3925-34. doi: 10.1074/jbc.M805081200. Epub 2008 Nov 24.

14.

Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.

Michailidou Z, Carter RN, Marshall E, Sutherland HG, Brownstein DG, Owen E, Cockett K, Kelly V, Ramage L, Al-Dujaili EA, Ross M, Maraki I, Newton K, Holmes MC, Seckl JR, Morton NM, Kenyon CJ, Chapman KE.

FASEB J. 2008 Nov;22(11):3896-907. doi: 10.1096/fj.08-111914. Epub 2008 Aug 12.

15.

A missense mutation in the murine Opa3 gene models human Costeff syndrome.

Davies VJ, Powell KA, White KE, Yip W, Hogan V, Hollins AJ, Davies JR, Piechota M, Brownstein DG, Moat SJ, Nichols PP, Wride MA, Boulton ME, Votruba M.

Brain. 2008 Feb;131(Pt 2):368-80. doi: 10.1093/brain/awm333.

PMID:
18222992
16.

A neurological phenotype in mice with DNA repair gene Ercc1 deficiency.

Lawrence NJ, Sacco JJ, Brownstein DG, Gillingwater TH, Melton DW.

DNA Repair (Amst). 2008 Feb 1;7(2):281-91. doi: 10.1016/j.dnarep.2007.10.005. Epub 2007 Dec 3.

PMID:
18221731
17.

Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis.

Patek CE, Arends MJ, Wallace WA, Luo F, Hagan S, Brownstein DG, Rose L, Devenney PS, Walker M, Plowman SJ, Berry RL, Kolch W, Sansom OJ, Harrison DJ, Hooper ML.

Exp Cell Res. 2008 Mar 10;314(5):1105-14. Epub 2007 Nov 17.

PMID:
18062963
18.

Effects on kidney disease, fertility and development in mice inheriting a protein-truncating Denys-Drash syndrome allele (Wt1tmT396).

Patek CE, Brownstein DG, Fleming S, Wroe C, Rose L, Webb A, Berry RL, Devenney PS, Walker M, Maddocks OD, Lawrence NJ, Harrison DJ, Wood KM, Miles CG, Hooper ML.

Transgenic Res. 2008 Jun;17(3):459-75. Epub 2007 Nov 27.

PMID:
18040647
19.

A switch in the mechanism of hypertension in the syndrome of apparent mineralocorticoid excess.

Bailey MA, Paterson JM, Hadoke PW, Wrobel N, Bellamy CO, Brownstein DG, Seckl JR, Mullins JJ.

J Am Soc Nephrol. 2008 Jan;19(1):47-58. Epub 2007 Nov 21.

20.

Variations in humanized and defined culture conditions supporting derivation of new human embryonic stem cell lines.

Fletcher JM, Ferrier PM, Gardner JO, Harkness L, Dhanjal S, Serhal P, Harper J, Delhanty J, Brownstein DG, Prasad YR, Lebkowski J, Mandalam R, Wilmut I, De Sousa PA.

Cloning Stem Cells. 2006 Winter;8(4):319-34.

PMID:
17196096
21.

Disruption of Ledgf/Psip1 results in perinatal mortality and homeotic skeletal transformations.

Sutherland HG, Newton K, Brownstein DG, Holmes MC, Kress C, Semple CA, Bickmore WA.

Mol Cell Biol. 2006 Oct;26(19):7201-10.

22.

Mice with skin-specific DNA repair gene (Ercc1) inactivation are hypersensitive to ultraviolet irradiation-induced skin cancer and show more rapid actinic progression.

Doig J, Anderson C, Lawrence NJ, Selfridge J, Brownstein DG, Melton DW.

Oncogene. 2006 Oct 12;25(47):6229-38. Epub 2006 May 8.

PMID:
16682947
23.

The K-Ras 4A isoform promotes apoptosis but does not affect either lifespan or spontaneous tumor incidence in aging mice.

Plowman SJ, Arends MJ, Brownstein DG, Luo F, Devenney PS, Rose L, Ritchie AM, Berry RL, Harrison DJ, Hooper ML, Patek CE.

Exp Cell Res. 2006 Jan 1;312(1):16-26. Epub 2005 Nov 4.

PMID:
16271715
24.

Dominant mutations of Col4a1 result in basement membrane defects which lead to anterior segment dysgenesis and glomerulopathy.

Van Agtmael T, Schlötzer-Schrehardt U, McKie L, Brownstein DG, Lee AW, Cross SH, Sado Y, Mullins JJ, Pöschl E, Jackson IJ.

Hum Mol Genet. 2005 Nov 1;14(21):3161-8. Epub 2005 Sep 13.

PMID:
16159887
25.

A novel transmembrane MSP-containing protein that plays a role in right ventricle development.

Pall GS, Wallis J, Axton R, Brownstein DG, Gautier P, Buerger K, Mulford C, Mullins JJ, Forrester LM.

Genomics. 2004 Dec;84(6):1051-9.

PMID:
15533722
26.

Alopecia areata with lymphocytic mural folliculitis affecting the isthmus in a thoroughbred mare.

Colombo S, Keen JA, Brownstein DG, Rhind SM, McGorum BC, Hill PB.

Vet Dermatol. 2004 Aug;15(4):260-5.

PMID:
15305934
27.

Role of tachykinins in the host response to murine gammaherpesvirus infection.

Payne CM, Heggie CJ, Brownstein DG, Stewart JP, Quinn JP.

J Virol. 2001 Nov;75(21):10467-71.

28.

Metastatic large intestinal adenocarcinoma in two rhesus macaques (Macaca mulatta).

Kerrick GP, Brownstein DG.

Contemp Top Lab Anim Sci. 2000 Jul;39(4):40-2.

PMID:
11487229
29.
30.

Analysis of a novel strain of murine gammaherpesvirus reveals a genomic locus important for acute pathogenesis.

Macrae AI, Dutia BM, Milligan S, Brownstein DG, Allen DJ, Mistrikova J, Davison AJ, Nash AA, Stewart JP.

J Virol. 2001 Jun;75(11):5315-27.

31.

Dual infection with Pneumocystis carinii and Pasteurella pneumotropica in B cell-deficient mice: diagnosis and therapy.

Macy JD Jr, Weir EC, Compton SR, Shlomchik MJ, Brownstein DG.

Comp Med. 2000 Feb;50(1):49-55.

PMID:
10987669
32.

Genetically engineered mice: the holes in the sum of the parts.

Brownstein DG.

Lab Anim Sci. 1998 Apr;48(2):121-2. Review. No abstract available.

PMID:
10090002
33.

Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction.

St John MA, Tao W, Fei X, Fukumoto R, Carcangiu ML, Brownstein DG, Parlow AF, McGrath J, Xu T.

Nat Genet. 1999 Feb;21(2):182-6.

PMID:
9988269
34.

Comparative genetics of resistance to viruses.

Brownstein DG.

Am J Hum Genet. 1998 Feb;62(2):211-4. Review. No abstract available.

36.

Pancreatitis and pregnancy toxemia in a New Zealand white rabbit.

Leland SE, Brownstein DG, Weir EC.

Contemp Top Lab Anim Sci. 1995 Nov;34(6):84-5. No abstract available.

PMID:
16457536
37.
39.

Papilloma formation in human foreskin xenografts after inoculation of human papillomavirus type 16 DNA.

Brandsma JL, Brownstein DG, Xiao W, Longley BJ.

J Virol. 1995 Apr;69(4):2716-21.

40.

Sendai viral pneumonia in aged BALB/c mice.

Jacoby RO, Bhatt PN, Barthold SW, Brownstein DG.

Exp Gerontol. 1994 Jan-Feb;29(1):89-100.

PMID:
8187844
41.

Cavernous lymphangioma in a squirrel monkey.

King CS, Streett JW, Brownstein DG.

Lab Anim Sci. 1993 Jun;43(3):252-4. No abstract available.

PMID:
8355487
42.

Immunogen-induced enhanced pulmonary histopathology in the RSV cotton rat model.

Hildreth SW, Baggs RR, Brownstein DG, Castleman WL, Paradiso PR.

Vaccine. 1993;11(6):689-90. No abstract available.

PMID:
8322496
44.
45.

Serial backcross analysis of genetic resistance to mousepox, using marker loci for Rmp-2 and Rmp-3.

Brownstein DG, Bhatt PN, Gras L, Budris T.

J Virol. 1992 Dec;66(12):7073-9.

46.

Endometrial venous aneurysms in three New Zealand white rabbits.

Bray MV, Weir EC, Brownstein DG, Delano ML.

Lab Anim Sci. 1992 Aug;42(4):360-2.

PMID:
1434495
48.

Hydrometra in a New Zealand white rabbit.

Bray MV, Gaertner DJ, Brownstein DG, Moody KD.

Lab Anim Sci. 1991 Dec;41(6):628-9. No abstract available.

PMID:
1667213
49.

Cryptosporidiosis in suckling laboratory rats.

Moody KD, Brownstein DG, Johnson EA.

Lab Anim Sci. 1991 Dec;41(6):625-7. No abstract available.

PMID:
1667212
50.

Pathogenesis of infection with a virulent allotropic variant of minute virus of mice and regulation by host genotype.

Brownstein DG, Smith AL, Jacoby RO, Johnson EA, Hansen G, Tattersall P.

Lab Invest. 1991 Sep;65(3):357-64.

PMID:
1653878

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