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Items: 1 to 50 of 175

1.

The (chain) terminators.

Brownlee GG.

Nat Rev Mol Cell Biol. 2019 Jan;20(1):2. doi: 10.1038/s41580-018-0063-5. No abstract available.

PMID:
30228347
2.

The Legacy of Fred Sanger-100 Years on from 1918.

Brownlee GG.

J Mol Biol. 2018 Aug 17;430(17):2661-2669. doi: 10.1016/j.jmb.2018.05.034. Epub 2018 May 29. No abstract available.

PMID:
29857002
3.

Frederick Sanger (1918-2013).

Brownlee GG.

Curr Biol. 2013 Dec 16;23(24):R1074-6. No abstract available.

4.

Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus.

Gabriel G, Klingel K, Otte A, Thiele S, Hudjetz B, Arman-Kalcek G, Sauter M, Shmidt T, Rother F, Baumgarte S, Keiner B, Hartmann E, Bader M, Brownlee GG, Fodor E, Klenk HD.

Nat Commun. 2011 Jan 18;2:156.

5.

Correlation between polymerase activity and pathogenicity in two duck H5N1 influenza viruses suggests that the polymerase contributes to pathogenicity.

Leung BW, Chen H, Brownlee GG.

Virology. 2010 May 25;401(1):96-106. doi: 10.1016/j.virol.2010.01.036. Epub 2010 Mar 7.

6.

A quantitative strategy to detect changes in accessibility of protein regions to chemical modification on heterodimerization.

Dreger M, Leung BW, Brownlee GG, Deng T.

Protein Sci. 2009 Jul;18(7):1448-58. doi: 10.1002/pro.159.

7.

The N-terminal region of the PA subunit of the RNA polymerase of influenza A/HongKong/156/97 (H5N1) influences promoter binding.

Kashiwagi T, Leung BW, Deng T, Chen H, Brownlee GG.

PLoS One. 2009;4(5):e5473. doi: 10.1371/journal.pone.0005473. Epub 2009 May 7.

8.

Role of initiating nucleoside triphosphate concentrations in the regulation of influenza virus replication and transcription.

Vreede FT, Gifford H, Brownlee GG.

J Virol. 2008 Jul;82(14):6902-10. doi: 10.1128/JVI.00627-08. Epub 2008 May 7. Erratum in: J Virol. 2008 Sep;82(18):9304.

9.

Differential role of the influenza A virus polymerase PA subunit for vRNA and cRNA promoter binding.

Maier HJ, Kashiwagi T, Hara K, Brownlee GG.

Virology. 2008 Jan 5;370(1):194-204. Epub 2007 Oct 1.

10.

Influenza virion-derived viral ribonucleoproteins synthesize both mRNA and cRNA in vitro.

Vreede FT, Brownlee GG.

J Virol. 2007 Mar;81(5):2196-204. Epub 2006 Dec 13.

11.

Role of the influenza virus heterotrimeric RNA polymerase complex in the initiation of replication.

Deng T, Sharps JL, Brownlee GG.

J Gen Virol. 2006 Nov;87(Pt 11):3373-7.

PMID:
17030872
12.

Role of ran binding protein 5 in nuclear import and assembly of the influenza virus RNA polymerase complex.

Deng T, Engelhardt OG, Thomas B, Akoulitchev AV, Brownlee GG, Fodor E.

J Virol. 2006 Dec;80(24):11911-9. Epub 2006 Sep 27.

14.

A new promoter-binding site in the PB1 subunit of the influenza A virus polymerase.

Jung TE, Brownlee GG.

J Gen Virol. 2006 Mar;87(Pt 3):679-88.

PMID:
16476991
16.

Characterization of a mitochondrial-targeting signal in the PB2 protein of influenza viruses.

Carr SM, Carnero E, García-Sastre A, Brownlee GG, Fodor E.

Virology. 2006 Jan 20;344(2):492-508. Epub 2005 Oct 18.

18.

Recognition of mRNA cap structures by viral and cellular proteins.

Fechter P, Brownlee GG.

J Gen Virol. 2005 May;86(Pt 5):1239-49. Review.

PMID:
15831934
19.
20.

Orthomyxovirus replication, transcription, and polyadenylation.

Neumann G, Brownlee GG, Fodor E, Kawaoka Y.

Curr Top Microbiol Immunol. 2004;283:121-43. Review.

PMID:
15298169
21.
22.
23.

Two aromatic residues in the PB2 subunit of influenza A RNA polymerase are crucial for cap binding.

Fechter P, Mingay L, Sharps J, Chambers A, Fodor E, Brownlee GG.

J Biol Chem. 2003 May 30;278(22):20381-8. Epub 2003 Mar 19.

24.
25.

A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase inhibits endonucleolytic cleavage of capped RNAs.

Fodor E, Crow M, Mingay LJ, Deng T, Sharps J, Fechter P, Brownlee GG.

J Virol. 2002 Sep;76(18):8989-9001.

26.
28.

The predicted antigenicity of the haemagglutinin of the 1918 Spanish influenza pandemic suggests an avian origin.

Brownlee GG, Fodor E.

Philos Trans R Soc Lond B Biol Sci. 2001 Dec 29;356(1416):1871-6.

29.
30.

Messenger RNAs that are not synthesized by RNA polymerase II can be 3' end cleaved and polyadenylated.

Fodor E, Mikulasova A, Mingay LJ, Poon LL, Brownlee GG.

EMBO Rep. 2000 Dec;1(6):513-8.

31.

DNA vaccination against respiratory influenza virus infection.

Wong JP, Zabielski MA, Schmaltz FL, Brownlee GG, Bussey LA, Marshall K, Borralho T, Nagata LP.

Vaccine. 2001 Mar 21;19(17-19):2461-7.

PMID:
11257378
32.
33.

Reduced levels of neuraminidase of influenza A viruses correlate with attenuated phenotypes in mice.

Solorzano A, Zheng H, Fodor E, Brownlee GG, Palese P, García-Sastre A.

J Gen Virol. 2000 Mar;81(Pt 3):737-42.

PMID:
10675411
34.
35.

Rescue of influenza A virus from recombinant DNA.

Fodor E, Devenish L, Engelhardt OG, Palese P, Brownlee GG, García-Sastre A.

J Virol. 1999 Nov;73(11):9679-82.

37.

A hairpin loop at the 5' end of influenza A virus virion RNA is required for synthesis of poly(A)+ mRNA in vitro.

Pritlove DC, Poon LL, Devenish LJ, Leahy MB, Brownlee GG.

J Virol. 1999 Mar;73(3):2109-14.

38.
39.

Attenuation of influenza A virus mRNA levels by promoter mutations.

Fodor E, Palese P, Brownlee GG, García-Sastre A.

J Virol. 1998 Aug;72(8):6283-90.

40.
41.

Cap ribose methylation of c-mos mRNA stimulates translation and oocyte maturation in Xenopus laevis.

Kuge H, Brownlee GG, Gershon PD, Richter JD.

Nucleic Acids Res. 1998 Jul 1;26(13):3208-14.

42.

Long-term expression of human clotting factor IX from retrovirally transduced primary human keratinocytes in vivo.

White SJ, Page SM, Margaritis P, Brownlee GG.

Hum Gene Ther. 1998 May 20;9(8):1187-95.

PMID:
9625258
43.
44.

Haemophilia B: database of point mutations and short additions and deletions--eighth edition.

Giannelli F, Green PM, Sommer SS, Poon M, Ludwig M, Schwaab R, Reitsma PH, Goossens M, Yoshioka A, Figueiredo MS, Brownlee GG.

Nucleic Acids Res. 1998 Jan 1;26(1):265-8.

46.
47.

Clotting factor IX levels in C/EBP alpha knockout mice.

Davies N, Austen DE, Wilde MD, Darlington GJ, Brownlee GG.

Br J Haematol. 1997 Dec;99(3):578-9.

PMID:
9401069
48.

An ex vivo keratinocyte model for gene therapy of hemophilia B.

Page SM, Brownlee GG.

J Invest Dermatol. 1997 Aug;109(2):139-45.

49.

Further evidence for the importance of an androgen response element in the factor IX promoter.

Morgan GE, Rowley G, Green PM, Chisholm M, Giannelli F, Brownlee GG.

Br J Haematol. 1997 Jul;98(1):79-85.

PMID:
9233568
50.

Mutational analysis of the RNA-fork model of the influenza A virus vRNA promoter in vivo.

Kim HJ, Fodor E, Brownlee GG, Seong BL.

J Gen Virol. 1997 Feb;78 ( Pt 2):353-7.

PMID:
9018057

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