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Genome-wide Significance Thresholds for Admixture Mapping Studies.

Grinde KE, Brown LA, Reiner AP, Thornton TA, Browning SR.

Am J Hum Genet. 2019 Mar 7;104(3):454-465. doi: 10.1016/j.ajhg.2019.01.008. Epub 2019 Feb 14.


Admixture mapping identifies novel loci for obstructive sleep apnea in Hispanic/Latino Americans.

Wang H, Cade BE, Sofer T, Sands SA, Chen H, Browning SR, Stilp AM, Louie TL, Thornton TA, Johnson WC, Below JE, Conomos MP, Evans DS, Gharib SA, Guo X, Wood AC, Mei H, Yaffe K, Loredo JS, Ramos AR, Barrett-Connor E, Ancoli-Israel S, Zee PC, Arens R, Shah NA, Taylor KD, Tranah GJ, Stone KL, Hanis CL, Wilson JG, Gottlieb DJ, Patel SR, Rice K, Post WS, Rotter JI, Sunyaev SR, Cai J, Lin X, Purcell SM, Laurie CC, Saxena R, Redline S, Zhu X.

Hum Mol Genet. 2019 Feb 15;28(4):675-687. doi: 10.1093/hmg/ddy387.


A One-Penny Imputed Genome from Next-Generation Reference Panels.

Browning BL, Zhou Y, Browning SR.

Am J Hum Genet. 2018 Sep 6;103(3):338-348. doi: 10.1016/j.ajhg.2018.07.015. Epub 2018 Aug 9.


Ancestry-specific recent effective population size in the Americas.

Browning SR, Browning BL, Daviglus ML, Durazo-Arvizu RA, Schneiderman N, Kaplan RC, Laurie CC.

PLoS Genet. 2018 May 24;14(5):e1007385. doi: 10.1371/journal.pgen.1007385. eCollection 2018 May.


Missed Work Due to Occupational Illness among Hispanic Horse Workers.

Bush AM, Westneat S, Browning SR, Swanberg J.

J Agric Saf Health. 2018 May 7;24(2):89-107. doi: 10.13031/jash.12735.


POPdemog: visualizing population demographic history from simulation scripts.

Zhou Y, Tian X, Browning BL, Browning SR.

Bioinformatics. 2018 Aug 15;34(16):2854-2855. doi: 10.1093/bioinformatics/bty184.


Analysis of Human Sequence Data Reveals Two Pulses of Archaic Denisovan Admixture.

Browning SR, Browning BL, Zhou Y, Tucci S, Akey JM.

Cell. 2018 Mar 22;173(1):53-61.e9. doi: 10.1016/j.cell.2018.02.031. Epub 2018 Mar 15.


Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits.

Sofer T, Baier LJ, Browning SR, Thornton TA, Talavera GA, Wassertheil-Smoller S, Daviglus ML, Hanson R, Kobes S, Cooper RS, Cai J, Levy D, Reiner AP, Franceschini N.

PLoS One. 2017 Nov 20;12(11):e0188400. doi: 10.1371/journal.pone.0188400. eCollection 2017.


Benefits Among Patients with Alpha-1 Antitrypsin Deficiency Enrolled in a Disease Management and Prevention Program.

Perkins JT, Choate R, Mannino DM, Browning SR, Sandhaus RA.

Chronic Obstr Pulm Dis. 2016 Dec 24;4(1):56-64. doi: 10.15326/jcopdf.4.1.2016.0161.


Different types of housing and respiratory health outcomes.

Gan WQ, Sanderson WT, Browning SR, Mannino DM.

Prev Med Rep. 2017 Jun 8;7:124-129. doi: 10.1016/j.pmedr.2017.05.018. eCollection 2017 Sep.


Genome-wide association study of heart rate and its variability in Hispanic/Latino cohorts.

Kerr KF, Avery CL, Lin HJ, Raffield LM, Zhang QS, Browning BL, Browning SR, Conomos MP, Gogarten SM, Laurie CC, Sofer T, Thornton TA, Hohensee C, Jackson RD, Kooperberg C, Li Y, Méndez-Giráldez R, Perez MV, Peters U, Reiner AP, Zhang ZM, Yao J, Sotoodehnia N, Taylor KD, Guo X, Lange LA, Soliman EZ, Wilson JG, Rotter JI, Heckbert SR, Jain D, Whitsel EA.

Heart Rhythm. 2017 Nov;14(11):1675-1684. doi: 10.1016/j.hrthm.2017.06.018. Epub 2017 Jun 10.


Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.

Hodonsky CJ, Jain D, Schick UM, Morrison JV, Brown L, McHugh CP, Schurmann C, Chen DD, Liu YM, Auer PL, Laurie CA, Taylor KD, Browning BL, Li Y, Papanicolaou G, Rotter JI, Kurita R, Nakamura Y, Browning SR, Loos RJF, North KE, Laurie CC, Thornton TA, Pankratz N, Bauer DE, Sofer T, Reiner AP.

PLoS Genet. 2017 Apr 28;13(4):e1006760. doi: 10.1371/journal.pgen.1006760. eCollection 2017 Apr.


Geographical Clusters and Predictors of Rabies in Three Southeastern States.

Reilly S, Sanderson WT, Christian WJ, Browning SR.

Vector Borne Zoonotic Dis. 2017 Jun;17(6):432-438. doi: 10.1089/vbz.2016.2061. Epub 2017 Apr 18.


Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos.

Jain D, Hodonsky CJ, Schick UM, Morrison JV, Minnerath S, Brown L, Schurmann C, Liu Y, Auer PL, Laurie CA, Taylor KD, Browning BL, Papanicolaou G, Browning SR, Loos RJF, North KE, Thyagarajan B, Laurie CC, Thornton TA, Sofer T, Reiner AP.

Hum Mol Genet. 2017 Mar 15;26(6):1193-1204. doi: 10.1093/hmg/ddx024.


Farm work injuries among a cohort of children in Kentucky, USA.

Browning SR, Westneat SC, Reed DB.

Ann Agric Environ Med. 2016 Dec 23;23(4):604-611. doi: 10.5604/12321966.1226854.


Robust Inference of Identity by Descent from Exome-Sequencing Data.

Fu W, Browning SR, Browning BL, Akey JM.

Am J Hum Genet. 2016 Nov 3;99(5):1106-1116. doi: 10.1016/j.ajhg.2016.09.011. Epub 2016 Oct 13.


Poor safety climate, long work hours, and musculoskeletal discomfort among Latino horse farm workers.

Swanberg J, Clouser JM, Gan W, Flunker JC, Westneat S, Browning SR.

Arch Environ Occup Health. 2017 Sep 3;72(5):264-271. doi: 10.1080/19338244.2016.1216387. Epub 2016 Aug 11.


Local Ancestry Inference in a Large US-Based Hispanic/Latino Study: Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Browning SR, Grinde K, Plantinga A, Gogarten SM, Stilp AM, Kaplan RC, Avilés-Santa ML, Browning BL, Laurie CC.

G3 (Bethesda). 2016 Jun 1;6(6):1525-34. doi: 10.1534/g3.116.028779.


ASAFE: ancestry-specific allele frequency estimation.

Zhang QS, Browning BL, Browning SR.

Bioinformatics. 2016 Jul 15;32(14):2227-9. doi: 10.1093/bioinformatics/btw220. Epub 2016 May 3.


Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans.

Schick UM, Jain D, Hodonsky CJ, Morrison JV, Davis JP, Brown L, Sofer T, Conomos MP, Schurmann C, McHugh CP, Nelson SC, Vadlamudi S, Stilp A, Plantinga A, Baier L, Bien SA, Gogarten SM, Laurie CA, Taylor KD, Liu Y, Auer PL, Franceschini N, Szpiro A, Rice K, Kerr KF, Rotter JI, Hanson RL, Papanicolaou G, Rich SS, Loos RJ, Browning BL, Browning SR, Weir BS, Laurie CC, Mohlke KL, North KE, Thornton TA, Reiner AP.

Am J Hum Genet. 2016 Feb 4;98(2):229-42. doi: 10.1016/j.ajhg.2015.12.003. Epub 2016 Jan 21.


Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos.

Conomos MP, Laurie CA, Stilp AM, Gogarten SM, McHugh CP, Nelson SC, Sofer T, Fernández-Rhodes L, Justice AE, Graff M, Young KL, Seyerle AA, Avery CL, Taylor KD, Rotter JI, Talavera GA, Daviglus ML, Wassertheil-Smoller S, Schneiderman N, Heiss G, Kaplan RC, Franceschini N, Reiner AP, Shaffer JR, Barr RG, Kerr KF, Browning SR, Browning BL, Weir BS, Avilés-Santa ML, Papanicolaou GJ, Lumley T, Szpiro AA, North KE, Rice K, Thornton TA, Laurie CC.

Am J Hum Genet. 2016 Jan 7;98(1):165-84. doi: 10.1016/j.ajhg.2015.12.001.


Genotype Imputation with Millions of Reference Samples.

Browning BL, Browning SR.

Am J Hum Genet. 2016 Jan 7;98(1):116-26. doi: 10.1016/j.ajhg.2015.11.020.


Accurate Non-parametric Estimation of Recent Effective Population Size from Segments of Identity by Descent.

Browning SR, Browning BL.

Am J Hum Genet. 2015 Sep 3;97(3):404-18. doi: 10.1016/j.ajhg.2015.07.012. Epub 2015 Aug 20.


Phenotypic population screen identifies a new mutation in bovine DGAT1 responsible for unsaturated milk fat.

Lehnert K, Ward H, Berry SD, Ankersmit-Udy A, Burrett A, Beattie EM, Thomas NL, Harris B, Ford CA, Browning SR, Rawson P, Verkerk GA, van der Does Y, Adams LF, Davis SR, Jordan TW, MacGibbon AK, Spelman RJ, Snell RG.

Sci Rep. 2015 Feb 26;5:8484. doi: 10.1038/srep08484.


Genome-wide haplotypic testing in a Finnish cohort identifies a novel association with low-density lipoprotein cholesterol.

Zhang QS, Browning BL, Browning SR.

Eur J Hum Genet. 2015 May;23(5):672-7. doi: 10.1038/ejhg.2014.105. Epub 2014 Jun 4.


Self-reported head injury and risk of late-life impairment and AD pathology in an AD center cohort.

Abner EL, Nelson PT, Schmitt FA, Browning SR, Fardo DW, Wan L, Jicha GA, Cooper GE, Smith CD, Caban-Holt AM, Van Eldik LJ, Kryscio RJ.

Dement Geriatr Cogn Disord. 2014;37(5-6):294-306. doi: 10.1159/000355478. Epub 2013 Dec 31.


Efficient clustering of identity-by-descent between multiple individuals.

Qian Y, Browning BL, Browning SR.

Bioinformatics. 2014 Apr 1;30(7):915-22. doi: 10.1093/bioinformatics/btt734. Epub 2013 Dec 19.


Detecting identity by descent and estimating genotype error rates in sequence data.

Browning BL, Browning SR.

Am J Hum Genet. 2013 Nov 7;93(5):840-51. doi: 10.1016/j.ajhg.2013.09.014. Epub 2013 Oct 24.


Occupational health among Latino horse and crop workers in Kentucky: the role of work organization factors.

Swanberg JE, Clouser JM, Browning SR, Westneat SC, Marsh MK.

J Agromedicine. 2013;18(4):312-25. doi: 10.1080/1059924X.2013.826604.


Imputation-based genomic coverage assessments of current human genotyping arrays.

Nelson SC, Doheny KF, Pugh EW, Romm JM, Ling H, Laurie CA, Browning SR, Weir BS, Laurie CC.

G3 (Bethesda). 2013 Oct 3;3(10):1795-807. doi: 10.1534/g3.113.007161.


Cattle-related injuries and farm management practices on Kentucky beef cattle farms.

Browning SR, Westneat SC, Sanderson WT, Reed DB.

J Agric Saf Health. 2013 Jan;19(1):37-49.


Improving the accuracy and efficiency of identity-by-descent detection in population data.

Browning BL, Browning SR.

Genetics. 2013 Jun;194(2):459-71. doi: 10.1534/genetics.113.150029. Epub 2013 Mar 27.


Limited association between perceived control and health-related quality of life in patients with heart failure.

Banerjee T, Lee KS, Browning SR, Hopenhayn C, Westneat S, Biddle MJ, Arslanian-Engoren C, Eastwood JA, Mudd G, Moser DK.

J Cardiovasc Nurs. 2014 May-Jun;29(3):227-31. doi: 10.1097/JCN.0b013e31828b2b23.


Deletion at the SLC1A1 glutamate transporter gene co-segregates with schizophrenia and bipolar schizoaffective disorder in a 5-generation family.

Myles-Worsley M, Tiobech J, Browning SR, Korn J, Goodman S, Gentile K, Melhem N, Byerley W, Faraone SV, Middleton FA.

Am J Med Genet B Neuropsychiatr Genet. 2013 Mar;162B(2):87-95. doi: 10.1002/ajmg.b.32125. Epub 2013 Jan 22.


Platelet-rich plasma increases matrix metalloproteinases in cultures of human synovial fibroblasts.

Browning SR, Weiser AM, Woolf N, Golish SR, SanGiovanni TP, Scuderi GJ, Carballo C, Hanna LS.

J Bone Joint Surg Am. 2012 Dec 5;94(23):e1721-7. doi: 10.2106/JBJS.K.01501.


Identity-by-descent-based heritability analysis in the Northern Finland Birth Cohort.

Browning SR, Browning BL.

Hum Genet. 2013 Feb;132(2):129-38. doi: 10.1007/s00439-012-1230-y. Epub 2012 Sep 29. Erratum in: Hum Genet. 2013 Aug;132(8):957-8.


Identity by descent between distant relatives: detection and applications.

Browning SR, Browning BL.

Annu Rev Genet. 2012;46:617-33. doi: 10.1146/annurev-genet-110711-155534. Epub 2012 Sep 17. Review.


Detecting rare variant associations by identity-by-descent mapping in case-control studies.

Browning SR, Thompson EA.

Genetics. 2012 Apr;190(4):1521-31. doi: 10.1534/genetics.111.136937. Epub 2012 Jan 20.


Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

Patsopoulos NA; Bayer Pharma MS Genetics Working Group; Steering Committees of Studies Evaluating IFNβ-1b and a CCR1-Antagonist; ANZgene Consortium; GeneMSA; International Multiple Sclerosis Genetics Consortium, Esposito F, Reischl J, Lehr S, Bauer D, Heubach J, Sandbrink R, Pohl C, Edan G, Kappos L, Miller D, Montalbán J, Polman CH, Freedman MS, Hartung HP, Arnason BG, Comi G, Cook S, Filippi M, Goodin DS, Jeffery D, O'Connor P, Ebers GC, Langdon D, Reder AT, Traboulsee A, Zipp F, Schimrigk S, Hillert J, Bahlo M, Booth DR, Broadley S, Brown MA, Browning BL, Browning SR, Butzkueven H, Carroll WM, Chapman C, Foote SJ, Griffiths L, Kermode AG, Kilpatrick TJ, Lechner-Scott J, Marriott M, Mason D, Moscato P, Heard RN, Pender MP, Perreau VM, Perera D, Rubio JP, Scott RJ, Slee M, Stankovich J, Stewart GJ, Taylor BV, Tubridy N, Willoughby E, Wiley J, Matthews P, Boneschi FM, Compston A, Haines J, Hauser SL, McCauley J, Ivinson A, Oksenberg JR, Pericak-Vance M, Sawcer SJ, De Jager PL, Hafler DA, de Bakker PI.

Ann Neurol. 2011 Dec;70(6):897-912. doi: 10.1002/ana.22609. Erratum in: Ann Neurol. 2013 Apr;73(4):561.


Performance of genotype imputation for rare variants identified in exons and flanking regions of genes.

Li L, Li Y, Browning SR, Browning BL, Slater AJ, Kong X, Aponte JL, Mooser VE, Chissoe SL, Whittaker JC, Nelson MR, Ehm MG.

PLoS One. 2011;6(9):e24945. doi: 10.1371/journal.pone.0024945. Epub 2011 Sep 19.


Haplotype phasing: existing methods and new developments.

Browning SR, Browning BL.

Nat Rev Genet. 2011 Sep 16;12(10):703-14. doi: 10.1038/nrg3054. Review.


Farmwork-related injury among farmers 50 years of age and older in Kentucky and South Carolina: a cohort study, 2002-2005.

Marcum JL, Browning SR, Reed DB, Charnigo RJ.

J Agric Saf Health. 2011 Jul;17(3):259-73.


Population structure can inflate SNP-based heritability estimates.

Browning SR, Browning BL.

Am J Hum Genet. 2011 Jul 15;89(1):191-3; author reply 193-5. doi: 10.1016/j.ajhg.2011.05.025. No abstract available.


Determinants of work hours among a cohort of male and female farmers 50 years and older in Kentucky and South Carolina (2002-2005).

Marcum JL, Browning SR, Reed DB, Charnigo RJ.

J Agromedicine. 2011 Jul-Sep;16(3):163-73. doi: 10.1080/1059924X.2011.581529.


A fast, powerful method for detecting identity by descent.

Browning BL, Browning SR.

Am J Hum Genet. 2011 Feb 11;88(2):173-82. doi: 10.1016/j.ajhg.2011.01.010.


A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis.

Field J, Browning SR, Johnson LJ, Danoy P, Varney MD, Tait BD, Gandhi KS, Charlesworth JC, Heard RN; Australia and New Zealand Multiple Sclerosis Genetics Consortium, Stewart GJ, Kilpatrick TJ, Foote SJ, Bahlo M, Butzkueven H, Wiley J, Booth DR, Taylor BV, Brown MA, Rubio JP, Stankovich J.

PLoS One. 2010 Oct 26;5(10):e13454. doi: 10.1371/journal.pone.0013454.


Population structure with localized haplotype clusters.

Browning SR, Weir BS.

Genetics. 2010 Aug;185(4):1337-44. doi: 10.1534/genetics.110.116681. Epub 2010 May 10.


High-resolution detection of identity by descent in unrelated individuals.

Browning SR, Browning BL.

Am J Hum Genet. 2010 Apr 9;86(4):526-39. doi: 10.1016/j.ajhg.2010.02.021. Epub 2010 Mar 18.


Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies.

Bahlo M, Stankovich J, Danoy P, Hickey PF, Taylor BV, Browning SR; Australian and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Brown MA, Rubio JP.

Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):794-8. doi: 10.1158/1055-9965.EPI-09-0812. Epub 2010 Mar 3.


A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay.

Girirajan S, Rosenfeld JA, Cooper GM, Antonacci F, Siswara P, Itsara A, Vives L, Walsh T, McCarthy SE, Baker C, Mefford HC, Kidd JM, Browning SR, Browning BL, Dickel DE, Levy DL, Ballif BC, Platky K, Farber DM, Gowans GC, Wetherbee JJ, Asamoah A, Weaver DD, Mark PR, Dickerson J, Garg BP, Ellingwood SA, Smith R, Banks VC, Smith W, McDonald MT, Hoo JJ, French BN, Hudson C, Johnson JP, Ozmore JR, Moeschler JB, Surti U, Escobar LF, El-Khechen D, Gorski JL, Kussmann J, Salbert B, Lacassie Y, Biser A, McDonald-McGinn DM, Zackai EH, Deardorff MA, Shaikh TH, Haan E, Friend KL, Fichera M, Romano C, Gécz J, DeLisi LE, Sebat J, King MC, Shaffer LG, Eichler EE.

Nat Genet. 2010 Mar;42(3):203-9. doi: 10.1038/ng.534. Epub 2010 Feb 14.

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