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Items: 1 to 50 of 308

1.

Modulation of Transmembrane Domain Interactions in Neu Receptor Tyrosine Kinase by Membrane Fluidity and Cholesterol.

Hasan M, Patel D, Ellis N, Brown SP, Lewandowski JR, Dixon AM.

J Membr Biol. 2019 Jun 20. doi: 10.1007/s00232-019-00075-4. [Epub ahead of print]

PMID:
31222471
2.
3.

Resistance diagnostics as a public health tool to combat antibiotic resistance: A model-based evaluation.

McAdams D, Wollein Waldetoft K, Tedijanto C, Lipsitch M, Brown SP.

PLoS Biol. 2019 May 16;17(5):e3000250. doi: 10.1371/journal.pbio.3000250. eCollection 2019 May.

4.

Haemolymph removal by Varroa mite destabilizes the dynamical interaction between immune effectors and virus in bees, as predicted by Volterra's model.

Annoscia D, Brown SP, Di Prisco G, De Paoli E, Del Fabbro S, Frizzera D, Zanni V, Galbraith DA, Caprio E, Grozinger CM, Pennacchio F, Nazzi F.

Proc Biol Sci. 2019 Apr 24;286(1901):20190331. doi: 10.1098/rspb.2019.0331.

5.

Psychological Care Augmented by Telemedicine after a Polar Bear Encounter at an Arctic Research Station: A Case Report.

Brown SP, Davis HE, McGladrey L, Brooks L, Lorentzen AK, Penninga L, Davis C, Lemery J.

Telemed J E Health. 2019 Mar 25. doi: 10.1089/tmj.2019.0008. [Epub ahead of print]

PMID:
30912705
6.

International variation in survival after out-of-hospital cardiac arrest: A validation study of the Utstein template.

Dyson K, Brown SP, May S, Smith K, Koster RW, Beesems SG, Kuisma M, Salo A, Finn J, Sterz F, Nürnberger A, Morrison LJ, Olasveengen TM, Callaway CW, Shin SD, Gräsner JT, Daya M, Ma MH, Herlitz J, Strömsöe A, Aufderheide TP, Masterson S, Wang H, Christenson J, Stiell I, Vilke GM, Idris A, Nishiyama C, Iwami T, Nichol G.

Resuscitation. 2019 May;138:168-181. doi: 10.1016/j.resuscitation.2019.03.018. Epub 2019 Mar 18.

PMID:
30898569
7.

Microbial Ecology of Snow Reveals Taxa-Specific Biogeographical Structure.

Brown SP, Jumpponen A.

Microb Ecol. 2019 May;77(4):946-958. doi: 10.1007/s00248-019-01357-z. Epub 2019 Mar 13.

PMID:
30868207
8.

Individual- versus group-optimality in the production of secreted bacterial compounds.

Schiessl KT, Ross-Gillespie A, Cornforth DM, Weigert M, Bigosch C, Brown SP, Ackermann M, Kümmerli R.

Evolution. 2019 Apr;73(4):675-688. doi: 10.1111/evo.13701. Epub 2019 Feb 28.

PMID:
30793292
9.

Bystander automated external defibrillator application in non-shockable out-of-hospital cardiac arrest.

Pollack RA, Brown SP, May S, Rea T, Kudenchuk PJ, Weisfeldt ML.

Resuscitation. 2019 Apr;137:168-174. doi: 10.1016/j.resuscitation.2019.02.007. Epub 2019 Feb 18.

PMID:
30790694
10.

Pneumococcal quorum sensing drives an asymmetric owner-intruder competitive strategy during carriage via the competence regulon.

Shen P, Lees JA, Bee GCW, Brown SP, Weiser JN.

Nat Microbiol. 2019 Jan;4(1):198-208. doi: 10.1038/s41564-018-0314-4. Epub 2018 Dec 10.

PMID:
30546100
11.

Wood decomposition in aquatic and terrestrial ecosystems in the tropics: contrasting biotic and abiotic processes.

Jones JM, Heath KD, Ferrer A, Brown SP, Canam T, Dalling JW.

FEMS Microbiol Ecol. 2019 Jan 1;95(1). doi: 10.1093/femsec/fiy223.

PMID:
30445583
12.

Evolution of bacterial trade in a two-species community.

Farrell JM, Brown SP.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):11874-11875. doi: 10.1073/pnas.1817344115. Epub 2018 Nov 12. No abstract available.

13.

Environmentally Mediated Social Dilemmas.

Estrela S, Libby E, Van Cleve J, Débarre F, Deforet M, Harcombe WR, Peña J, Brown SP, Hochberg ME.

Trends Ecol Evol. 2019 Jan;34(1):6-18. doi: 10.1016/j.tree.2018.10.004. Epub 2018 Nov 8. Review.

PMID:
30415827
14.

Intraosseous versus intravenous access in patients with out-of-hospital cardiac arrest: Insights from the resuscitation outcomes consortium continuous chest compression trial.

Mody P, Brown SP, Kudenchuk PJ, Chan PS, Khera R, Ayers C, Pandey A, Kern KB, de Lemos JA, Link MS, Idris AH.

Resuscitation. 2019 Jan;134:69-75. doi: 10.1016/j.resuscitation.2018.10.031. Epub 2018 Nov 1.

PMID:
30391366
15.

AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies.

Caenepeel S, Brown SP, Belmontes B, Moody G, Keegan KS, Chui D, Whittington DA, Huang X, Poppe L, Cheng AC, Cardozo M, Houze J, Li Y, Lucas B, Paras NA, Wang X, Taygerly JP, Vimolratana M, Zancanella M, Zhu L, Cajulis E, Osgood T, Sun J, Damon L, Egan RK, Greninger P, McClanaghan JD, Gong J, Moujalled D, Pomilio G, Beltran P, Benes CH, Roberts AW, Huang DC, Wei A, Canon J, Coxon A, Hughes PE.

Cancer Discov. 2018 Dec;8(12):1582-1597. doi: 10.1158/2159-8290.CD-18-0387. Epub 2018 Sep 25.

PMID:
30254093
16.

Exploiting MCL1 Dependency with Combination MEK + MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in KRAS-Mutant Non-Small Cell Lung Cancer.

Nangia V, Siddiqui FM, Caenepeel S, Timonina D, Bilton SJ, Phan N, Gomez-Caraballo M, Archibald HL, Li C, Fraser C, Rigas D, Vajda K, Ferris LA, Lanuti M, Wright CD, Raskin KA, Cahill DP, Shin JH, Keyes C, Sequist LV, Piotrowska Z, Farago AF, Azzoli CG, Gainor JF, Sarosiek KA, Brown SP, Coxon A, Benes CH, Hughes PE, Hata AN.

Cancer Discov. 2018 Dec;8(12):1598-1613. doi: 10.1158/2159-8290.CD-18-0277. Epub 2018 Sep 25.

PMID:
30254092
17.

Protocols for Investigating the Leaf Mycobiome Using High-Throughput DNA Sequencing.

Brown SP, Leopold DR, Busby PE.

Methods Mol Biol. 2018;1848:39-51. doi: 10.1007/978-1-4939-8724-5_4.

PMID:
30182227
18.

An NMR crystallography investigation of furosemide.

Zilka M, Yates JR, Brown SP.

Magn Reson Chem. 2019 May;57(5):191-199. doi: 10.1002/mrc.4789. Epub 2018 Oct 11.

19.

The use of variable temperature 13 C solid-state MAS NMR and GIPAW DFT calculations to explore the dynamics of diethylcarbamazine citrate.

Venâncio T, Oliveira LM, Pawlak T, Ellena J, Boechat N, Brown SP.

Magn Reson Chem. 2019 May;57(5):200-210. doi: 10.1002/mrc.4790. Epub 2018 Oct 15.

PMID:
30114322
20.

A Tautoleptic Approach to Chiral Hydrogen-Bonded Supramolecular Tubular Polymers with Large Cavity.

Neniškis A, Račkauskaitė D, Shi Q, Robertson AJ, Marsh A, Ulčinas A, Valiokas R, Brown SP, Wärnmark K, Orentas E.

Chemistry. 2018 Sep 20;24(53):14028-14033. doi: 10.1002/chem.201803701. Epub 2018 Sep 6.

21.

The development of local circuits in the neocortex: recent lessons from the mouse visual cortex.

Chevée M, Brown SP.

Curr Opin Neurobiol. 2018 Dec;53:103-109. doi: 10.1016/j.conb.2018.06.009. Epub 2018 Jul 24. Review.

PMID:
30053693
22.

Discovery of AM-6226: A Potent and Orally Bioavailable GPR40 Full Agonist That Displays Efficacy in Nonhuman Primates.

Brown SP, Dransfield P, Vimolratana M, Zhu L, Luo J, Zhang J, Jiao X, Pattaropong V, Wong S, Zhuang R, Swaminath G, Houze JB, Lin DC.

ACS Med Chem Lett. 2018 Jun 6;9(7):757-760. doi: 10.1021/acsmedchemlett.8b00213. eCollection 2018 Jul 12.

PMID:
30034614
23.

Community interactions and spatial structure shape selection on antibiotic resistant lineages.

Estrela S, Brown SP.

PLoS Comput Biol. 2018 Jun 21;14(6):e1006179. doi: 10.1371/journal.pcbi.1006179. eCollection 2018 Jun.

24.

A Non-canonical Feedback Circuit for Rapid Interactions between Somatosensory Cortices.

Minamisawa G, Kwon SE, Chevée M, Brown SP, O'Connor DH.

Cell Rep. 2018 May 29;23(9):2718-2731.e6. doi: 10.1016/j.celrep.2018.04.115.

25.

The State of the Union Is Strong: a Review of ASM's 6th Conference on Cell-Cell Communication in Bacteria.

Brown SP, Blackwell HE, Hammer BK.

J Bacteriol. 2018 Jun 25;200(14). pii: e00291-18. doi: 10.1128/JB.00291-18. Print 2018 Jul 15. Review.

26.

Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests.

Pollack RA, Brown SP, Rea T, Aufderheide T, Barbic D, Buick JE, Christenson J, Idris AH, Jasti J, Kampp M, Kudenchuk P, May S, Muhr M, Nichol G, Ornato JP, Sopko G, Vaillancourt C, Morrison L, Weisfeldt M; ROC Investigators.

Circulation. 2018 May 15;137(20):2104-2113. doi: 10.1161/CIRCULATIONAHA.117.030700. Epub 2018 Feb 26.

27.

Variation in Activity State, Axonal Projection, and Position Define the Transcriptional Identity of Individual Neocortical Projection Neurons.

Chevée M, Robertson JJ, Cannon GH, Brown SP, Goff LA.

Cell Rep. 2018 Jan 9;22(2):441-455. doi: 10.1016/j.celrep.2017.12.046.

28.

Alternative therapeutics for self-limiting infections-An indirect approach to the antibiotic resistance challenge.

Wollein Waldetoft K, Brown SP.

PLoS Biol. 2017 Dec 28;15(12):e2003533. doi: 10.1371/journal.pbio.2003533. eCollection 2017 Dec.

29.

New Breakthroughs in Understanding the Role of Functional Interactions between the Neocortex and the Claustrum.

Brown SP, Mathur BN, Olsen SR, Luppi PH, Bickford ME, Citri A.

J Neurosci. 2017 Nov 8;37(45):10877-10881. doi: 10.1523/JNEUROSCI.1837-17.2017. Review.

30.

Isotope-Labeled Aspartate Sidechain as a Non-Perturbing Infrared Probe: Application to Investigate the Dynamics of a Carboxylate Buried Inside a Protein.

Abaskharon RM, Brown SP, Zhang W, Chen J, Smith AB 3rd, Gai F.

Chem Phys Lett. 2017 Sep 1;683:193-198. doi: 10.1016/j.cplett.2017.03.064. Epub 2017 Mar 23.

31.

Visualising crystal packing interactions in solid-state NMR: Concepts and applications.

Zilka M, Sturniolo S, Brown SP, Yates JR.

J Chem Phys. 2017 Oct 14;147(14):144203. doi: 10.1063/1.4996750.

PMID:
29031269
32.

Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3.

Wagman AS, Boyce RS, Brown SP, Fang E, Goff D, Jansen JM, Le VP, Levine BH, Ng SC, Ni ZJ, Nuss JM, Pfister KB, Ramurthy S, Renhowe PA, Ring DB, Shu W, Subramanian S, Zhou XA, Shafer CM, Harrison SD, Johnson KW, Bussiere DE.

J Med Chem. 2017 Oct 26;60(20):8482-8514. doi: 10.1021/acs.jmedchem.7b00922. Epub 2017 Oct 10.

PMID:
29016121
33.

Use of Immunolabeling to Analyze Stable, Dynamic, and Nascent Microtubules in the Zebrafish Embryo.

McFarland RJ, Brown SP, Vital E, Werner JM, Brewster RM.

J Vis Exp. 2017 Sep 20;(127). doi: 10.3791/55792.

34.

An even pattern of xylan substitution is critical for interaction with cellulose in plant cell walls.

Grantham NJ, Wurman-Rodrich J, Terrett OM, Lyczakowski JJ, Stott K, Iuga D, Simmons TJ, Durand-Tardif M, Brown SP, Dupree R, Busse-Wicher M, Dupree P.

Nat Plants. 2017 Nov;3(11):859-865. doi: 10.1038/s41477-017-0030-8. Epub 2017 Oct 9.

PMID:
28993612
35.

Corrigendum: Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep.

Liu K, Kim J, Kim DW, Stephanie Zhang Y, Bao H, Denaxa M, Lim SA, Kim E, Liu C, Wickersham IR, Pachnis V, Hattar S, Song J, Brown SP, Blackshaw S.

Nature. 2017 Oct 26;550(7677):548. doi: 10.1038/nature24274. Epub 2017 Sep 27.

36.

Ab initio random structure searching of organic molecular solids: assessment and validation against experimental data.

Zilka M, Dudenko DV, Hughes CE, Williams PA, Sturniolo S, Franks WT, Pickard CJ, Yates JR, Harris KDM, Brown SP.

Phys Chem Chem Phys. 2017 Oct 4;19(38):25949-25960. doi: 10.1039/c7cp04186a.

37.

Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep.

Liu K, Kim J, Kim DW, Zhang YS, Bao H, Denaxa M, Lim SA, Kim E, Liu C, Wickersham IR, Pachnis V, Hattar S, Song J, Brown SP, Blackshaw S.

Nature. 2017 Aug 31;548(7669):582-587. doi: 10.1038/nature23663. Epub 2017 Aug 23. Erratum in: Nature. 2017 Sep 27;:.

38.

Strong-coupling induced damping of spin-echo modulations in magic-angle-spinning NMR: Implications for J coupling measurements in disordered solids.

Guerry P, Brown SP, Smith ME.

J Magn Reson. 2017 Oct;283:22-32. doi: 10.1016/j.jmr.2017.08.006. Epub 2017 Aug 19.

PMID:
28843058
39.

Changes in the Excitability of Neocortical Neurons in a Mouse Model of Amyotrophic Lateral Sclerosis Are Not Specific to Corticospinal Neurons and Are Modulated by Advancing Disease.

Kim J, Hughes EG, Shetty AS, Arlotta P, Goff LA, Bergles DE, Brown SP.

J Neurosci. 2017 Sep 13;37(37):9037-9053. doi: 10.1523/JNEUROSCI.0811-17.2017. Epub 2017 Aug 17.

40.

Division of Labor, Bet Hedging, and the Evolution of Mixed Biofilm Investment Strategies.

Lowery NV, McNally L, Ratcliff WC, Brown SP.

MBio. 2017 Aug 8;8(4). pii: e00672-17. doi: 10.1128/mBio.00672-17.

41.

Assessing the Detection Limit of a Minority Solid-State Form of a Pharmaceutical by 1H Double-Quantum Magic-Angle Spinning Nuclear Magnetic Resonance Spectroscopy.

Maruyoshi K, Iuga D, Watts AE, Hughes CE, Harris KDM, Brown SP.

J Pharm Sci. 2017 Nov;106(11):3372-3377. doi: 10.1016/j.xphs.2017.07.014. Epub 2017 Jul 25.

42.

Cell-type specific differences in promoter activity of the ALS-linked C9orf72 mouse ortholog.

Langseth AJ, Kim J, Ugolino JE, Shah Y, Hwang HY, Wang J, Bergles DE, Brown SP.

Sci Rep. 2017 Jul 18;7(1):5685. doi: 10.1038/s41598-017-05864-2.

43.

The evolution of library design: crafting smart compound collections for phenotypic screens.

Spear KL, Brown SP.

Drug Discov Today Technol. 2017 Mar;23:61-67. doi: 10.1016/j.ddtec.2017.05.001. Epub 2017 May 30. Review.

PMID:
28647087
44.

The route of infection determines Wolbachia antibacterial protection in Drosophila.

Gupta V, Vasanthakrishnan RB, Siva-Jothy J, Monteith KM, Brown SP, Vale PF.

Proc Biol Sci. 2017 Jun 14;284(1856). pii: 20170809. doi: 10.1098/rspb.2017.0809.

45.
46.

Within-host interference competition can prevent invasion of rare parasites.

Quigley BJZ, Brown SP, Leggett HC, Scanlan PD, Buckling A.

Parasitology. 2018 May;145(6):770-774. doi: 10.1017/S003118201700052X. Epub 2017 May 15.

PMID:
28502267
47.

Probing intermolecular interactions in a diethylcarbamazine citrate salt by fast MAS 1H solid-state NMR spectroscopy and GIPAW calculations.

Venâncio T, Oliveira LM, Ellena J, Boechat N, Brown SP.

Solid State Nucl Magn Reson. 2017 Oct;87:73-79. doi: 10.1016/j.ssnmr.2017.02.006. Epub 2017 Mar 2.

PMID:
28342733
48.

Single-crystal X-ray diffraction and NMR crystallography of a 1:1 cocrystal of dithianon and pyrimethanil.

Pöppler AC, Corlett EK, Pearce H, Seymour MP, Reid M, Montgomery MG, Brown SP.

Acta Crystallogr C Struct Chem. 2017 Mar 1;73(Pt 3):149-156. doi: 10.1107/S2053229617000870. Epub 2017 Feb 6.

49.

Killing by Type VI secretion drives genetic phase separation and correlates with increased cooperation.

McNally L, Bernardy E, Thomas J, Kalziqi A, Pentz J, Brown SP, Hammer BK, Yunker PJ, Ratcliff WC.

Nat Commun. 2017 Feb 6;8:14371. doi: 10.1038/ncomms14371.

50.

Superhero physiology: the case for Captain America.

Brown SP, Smith JW, McAllister M, Joe L.

Adv Physiol Educ. 2017 Mar 1;41(1):16-24. doi: 10.1152/advan.00106.2016.

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