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Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial.

Brand DH, Tree AC, Ostler P, van der Voet H, Loblaw A, Chu W, Ford D, Tolan S, Jain S, Martin A, Staffurth J, Camilleri P, Kancherla K, Frew J, Chan A, Dayes IS, Henderson D, Brown S, Cruickshank C, Burnett S, Duffton A, Griffin C, Hinder V, Morrison K, Naismith O, Hall E, van As N; PACE Trial Investigators.

Lancet Oncol. 2019 Sep 17. pii: S1470-2045(19)30569-8. doi: 10.1016/S1470-2045(19)30569-8. [Epub ahead of print]


The evolving role of radiotherapy in non-small cell lung cancer.

Brown S, Banfill K, Aznar MC, Whitehurst P, Faivre Finn C.

Br J Radiol. 2019 Sep 19:20190524. doi: 10.1259/bjr.20190524. [Epub ahead of print]


The surgical nature of radiation oncology should be better reflected in pre-residency training.

McClelland S 3rd, Brown SA, Ramirez-Fort MK, Jaboin JJ, Zellars RC.

Rep Pract Oncol Radiother. 2019 Sep-Oct;24(5):507-508. doi: 10.1016/j.rpor.2019.07.011. Epub 2019 Aug 17. No abstract available.


The Synaptic Organization of Layer 6 Circuits Reveals Inhibition as a Major Output of a Neocortical Sublamina.

Frandolig JE, Matney CJ, Lee K, Kim J, Chevée M, Kim SJ, Bickert AA, Brown SP.

Cell Rep. 2019 Sep 17;28(12):3131-3143.e5. doi: 10.1016/j.celrep.2019.08.048.


Modified Antibiotic Adjuvant Ratios Can Slow and Steer the Evolution of Resistance: Co-amoxiclav as a Case Study.

Allen RC, Brown SP.

MBio. 2019 Sep 17;10(5). pii: e01831-19. doi: 10.1128/mBio.01831-19.


Interactions of the DASH Diet with the Renin-Angiotensin-Aldosterone System.

Maris SA, Williams JS, Sun B, Brown S, Mitchell GF, Conlin PR.

Curr Dev Nutr. 2019 Jul 31;3(9):nzz091. doi: 10.1093/cdn/nzz091. eCollection 2019 Sep.


Characterization of post-traumatic osteoarthritis in rats following ACL rupture by non-invasive knee injury (NIKI).

Brown S, Hornyak J, Jungels R, Shah YY, Yarmola EG, Allen KD, Sharma B.

J Orthop Res. 2019 Sep 14. doi: 10.1002/jor.24470. [Epub ahead of print]


Genetic underpinnings of recovery after stroke: an opportunity for gene discovery, risk stratification, and precision medicine.

Acosta JN, Brown SC, Falcone GJ.

Genome Med. 2019 Sep 13;11(1):58. doi: 10.1186/s13073-019-0671-5.


Community-engaged Evidence Synthesis to Inform Public Health Policy and Clinical Practice: A Case Study.

Springs S, Rofeberg V, Brown S, Boudreau S, Hey SP, Baruch J.

Med Care. 2019 Oct;57 Suppl 10 Suppl 3:S253-S258. doi: 10.1097/MLR.0000000000001180.


The vaginal microbiota and behavioral factors associated with genital Candida albicans detection in reproductive-age women.

Brown SE, Schwartz JA, Robinson CK, O'Hanlon DE, Bradford LL, He X, Mark KS, Bruno VM, Ravel J, Brotman RM.

Sex Transm Dis. 2019 Sep 10. doi: 10.1097/OLQ.0000000000001066. [Epub ahead of print]


Impact of Critical Illness on Resource Utilization: A Comparison of Use in the Year Before and After ICU Admission.

Hirshberg EL, Wilson EL, Stanfield V, Kuttler KG, Majercik S, Beesley SJ, Orme J, Hopkins RO, Brown SM.

Crit Care Med. 2019 Sep 12. doi: 10.1097/CCM.0000000000003970. [Epub ahead of print]


Intrusive imagery associated with pain.

Graham CJ, Brown SL, Vincent K, Horne AW.

BMJ. 2019 Sep 10;366:l5459. doi: 10.1136/bmj.l5459. No abstract available.


The Presence and Persistence of Unrealistic Expectations in Patients Undergoing Nerve Surgery.

Kirsch M, Brown S, Smith BW, Chang KWC, Koduri S, Yang LJS.

Neurosurgery. 2019 Aug 30. pii: nyz321. doi: 10.1093/neuros/nyz335. [Epub ahead of print]


Effects of Pharmacologically Induced Leydig Cell Testosterone Production on Intratesticular Testosterone and Spermatogenesis.

Chung JY, Brown S, Chen H, Liu J, Papadopoulos V, Zirkin B.

Biol Reprod. 2019 Sep 2. pii: ioz174. doi: 10.1093/biolre/ioz174. [Epub ahead of print]



Brown SR, Bodenheimer T, Kong M.

Ann Fam Med. 2019 Sep;17(5):470-471. doi: 10.1370/afm.2452. No abstract available.


Impact of a One-Time Interprofessional Education Event for Rehabilitation after Stroke for Students in the Health Professions.

Gras LZ, Brown S, Durnford S, Fishel S, Elich Monroe J, Plumeau K, Valdez Taves J.

J Allied Health. 2019 Fall;48(3):167-171.


Confirmatory Study of Time-Dependent Computed Tomographic Perfusion Thresholds for Use in Acute Ischemic Stroke.

Qiu W, Kuang H, Lee TY, Boers AM, Brown S, Muir K, Majoie CBLM, Dippel DWJ, White P, Guillemin F, Mitchell PJ, Dávalos A, Bracard S, Campbell B, Saver JL, Jovin TG, Hill MD, Demchuk AM, Goyal M, Menon BK; HERMES collaborators.

Stroke. 2019 Sep 4:STROKEAHA119026281. doi: 10.1161/STROKEAHA.119.026281. [Epub ahead of print]


Alcohol Expectancies Moderate the Association Between School Connectedness and Alcohol Consumption.

Cummins KM, Diep SA, Brown SA.

J Sch Health. 2019 Sep 2. doi: 10.1111/josh.12829. [Epub ahead of print]


'Wargaming with the chiefs': A novel pre-mortem exercise to enhance communication and well-being among 'top gun' chief residents.

Allespach H, Brown S, Bosire KM, Tornes L, Bagatell S.

Med Teach. 2019 Sep 2:1-3. doi: 10.1080/0142159X.2019.1656331. [Epub ahead of print]


Reduced Rank Least Squares for Real-Time Short Term Estimation of Mean Arterial Blood Pressure in Septic Patients Receiving Norepinephrine.

Tang Y, Brown S, Sorensen J, Harley JB.

IEEE J Transl Eng Health Med. 2019 Jun 4;7:4100209. doi: 10.1109/JTEHM.2019.2919020. eCollection 2019.


Maternal and Paternal Warmth Impact Recovery Support and Social Network Composition for Substance Dependent African American and Non-African American Women.

Brown S, Victor BG, Dayton CJ, Tracy EM.

Addict Res Theory. 2019;27(4):294-304. doi: 10.1080/16066359.2018.1515350. Epub 2019 Jan 7.


Dynamic- and Frequency-Specific Regulation of Sleep Oscillations by Cortical Potassium Channels.

Muheim CM, Spinnler A, Sartorius T, Dürr R, Huber R, Kabagema C, Ruth P, Brown SA.

Curr Biol. 2019 Aug 14. pii: S0960-9822(19)30936-4. doi: 10.1016/j.cub.2019.07.056. [Epub ahead of print]


The repeatability and reproducibility of the Sheffield Features of Gait Tool.

Birch I, Birch M, Rutler L, Brown S, Burgos LR, Otten B, Wiedemeijer M.

Sci Justice. 2019 Sep;59(5):544-551. doi: 10.1016/j.scijus.2019.04.001. Epub 2019 Apr 19.


Molecular Structure of Binary Chromium(III)-DNA Adducts.

Brown S, Lockart MM, Thomas CS, Bowman MK, Woski SA, Vincent JB.

Chembiochem. 2019 Aug 31. doi: 10.1002/cbic.201900436. [Epub ahead of print]


First report of using low-titer cold-stored type O whole blood in massive postpartum hemorrhage.

Bahr TM, DuPont TL, Morris DS, Pierson SE, Esplin MS, Brown SM, O'Brien EA, Ilstrup SJ, Christensen RD.

Transfusion. 2019 Aug 30. doi: 10.1111/trf.15492. [Epub ahead of print]


White matter alterations in early-stage Alzheimer's disease: A tract-specific study.

Wen Q, Mustafi SM, Li J, Risacher SL, Tallman E, Brown SA, West JD, Harezlak J, Farlow MR, Unverzagt FW, Gao S, Apostolova LG, Saykin AJ, Wu YC.

Alzheimers Dement (Amst). 2019 Aug 21;11:576-587. doi: 10.1016/j.dadm.2019.06.003. eCollection 2019 Dec.


Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial (gameChange).

Freeman D, Yu LM, Kabir T, Martin J, Craven M, Leal J, Lambe S, Brown S, Morrison A, Chapman K, Dudley R, O'Regan E, Rovira A, Goodsell A, Rosebrock L, Bergin A, Cryer TL, Robotham D, Andleeb H, Geddes JR, Hollis C, Clark DM, Waite F.

BMJ Open. 2019 Aug 27;9(8):e031606. doi: 10.1136/bmjopen-2019-031606.


Interleukin-15 Enhances Anti-GD2 Antibody-Mediated Cytotoxicity in an Orthotopic PDX Model of Neuroblastoma.

Nguyen R, Moustaki A, Norrie JL, Brown S, Akers WJ, Shirinifard A, Dyer MA.

Clin Cancer Res. 2019 Aug 27. pii: clincanres.1045.2019. doi: 10.1158/1078-0432.CCR-19-1045. [Epub ahead of print]


Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.

Dunbar LA, Patni P, Aguilar C, Mburu P, Corns L, Wells HR, Delmaghani S, Parker A, Johnson S, Williams D, Esapa CT, Simon MM, Chessum L, Newton S, Dorning J, Jeyarajan P, Morse S, Lelli A, Codner GF, Peineau T, Gopal SR, Alagramam KN, Hertzano R, Dulon D, Wells S, Williams FM, Petit C, Dawson SJ, Brown SD, Marcotti W, El-Amraoui A, Bowl MR.

EMBO Mol Med. 2019 Sep;11(9):e10288. doi: 10.15252/emmm.201910288. Epub 2019 Aug 26.


Identification of a novel allosteric GLP-1R antagonist HTL26119 using structure- based drug design.

O'Brien A, Andrews SP, Baig AH, Bortolato A, Brown AJH, Brown GA, Brown SH, Christopher JA, Congreve M, Cooke RM, De Graaf C, Errey JC, Fieldhouse C, Jazayeri A, Marshall FH, Mason JS, Mobarec JC, Okrasa K, Steele KN, Southall SM, Teobald I, Watson SP, Weir M.

Bioorg Med Chem Lett. 2019 Aug 9:126611. doi: 10.1016/j.bmcl.2019.08.015. [Epub ahead of print]


The dark genome and pleiotropy: challenges for precision medicine.

Brown SDM, Lad HV.

Mamm Genome. 2019 Aug 23. doi: 10.1007/s00335-019-09813-4. [Epub ahead of print]


Recovery of Curvularia mold from a duodenoscope after reprocessing in accordance with the manufacturer's cleaning protocol.

Schuman D, Brown S, Mistretta SM, Delano J, Iovine NM.

Am J Infect Control. 2019 Aug 20. pii: S0196-6553(19)30656-X. doi: 10.1016/j.ajic.2019.06.025. [Epub ahead of print]


The Immune Landscape of Cancer.

Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS; Cancer Genome Atlas Research Network, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I.

Immunity. 2019 Aug 20;51(2):411-412. doi: 10.1016/j.immuni.2019.08.004. No abstract available.


Highlights From the American Heart Association's EPI|LIFESTYLE 2019 Scientific Sessions.

Alonso A, Anderson MD, Bancks MP, Brown SA, Caughey MC, Chang AR, Delker E, Foti K, Gingras V, Nanna MG, Razavi AC, Scott J, Selvin E, Tcheandjieu C, Thomas AG, Turkson-Ocran RN, Webel A, Young DR, DeBarmore BM.

J Am Heart Assoc. 2019 Jun 4;8(11):e012925. doi: 10.1161/JAHA.119.012925. Epub 2019 Jun 1. No abstract available.


Percutaneous obliteration of the right ventricle to avoid coronary damage by sinusoids in patients with pulmonary atresia intact ventricular septum during staged single ventricle palliation.

Hubrechts J, Cools B, Brown SC, Eyskens B, Heying R, Boshoff D, Gewillig M.

Catheter Cardiovasc Interv. 2019 Aug 21. doi: 10.1002/ccd.28457. [Epub ahead of print]


Child, Family, and Case Characteristics Associated With Reentry Into Out-of-Home Care Among Children and Youth Involved With Child Protection Services.

Brown SM, Orsi R, Chen PCB.

Child Maltreat. 2019 Aug 20:1077559519869395. doi: 10.1177/1077559519869395. [Epub ahead of print]


Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis.

Consortium on Thyroid and Pregnancy—Study Group on Preterm Birth, Korevaar TIM, Derakhshan A, Taylor PN, Meima M, Chen L, Bliddal S, Carty DM, Meems M, Vaidya B, Shields B, Ghafoor F, Popova PV, Mosso L, Oken E, Suvanto E, Hisada A, Yoshinaga J, Brown SJ, Bassols J, Auvinen J, Bramer WM, López-Bermejo A, Dayan C, Boucai L, Vafeiadi M, Grineva EN, Tkachuck AS, Pop VJM, Vrijkotte TG, Guxens M, Chatzi L, Sunyer J, Jiménez-Zabala A, Riaño I, Murcia M, Lu X, Mukhtar S, Delles C, Feldt-Rasmussen U, Nelson SM, Alexander EK, Chaker L, Männistö T, Walsh JP, Pearce EN, Steegers EAP, Peeters RP.

JAMA. 2019 Aug 20;322(7):632-641. doi: 10.1001/jama.2019.10931.


Educational Curricula and Programs in Adolescent Medicine for Health Workers in Low- and Middle-Income Countries: A Scoping Review.

Miller KK, Brown SJ, Pfeffer B, Olupot-Olupot P, Kitaka S.

J Grad Med Educ. 2019 Aug;11(4 Suppl):64-72. doi: 10.4300/JGME-D-19-00052. Review.


Identifying the components of the solid-electrolyte interphase in Li-ion batteries.

Wang L, Menakath A, Han F, Wang Y, Zavalij PY, Gaskell KJ, Borodin O, Iuga D, Brown SP, Wang C, Xu K, Eichhorn BW.

Nat Chem. 2019 Sep;11(9):789-796. doi: 10.1038/s41557-019-0304-z. Epub 2019 Aug 19.


A large-scale analysis of task switching practice effects across the lifespan.

Steyvers M, Hawkins GE, Karayanidis F, Brown SD.

Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17735-17740. doi: 10.1073/pnas.1906788116. Epub 2019 Aug 19.


Sulfamate in environmental waters.

Van Stempvoort DR, Spoelstra J, Brown SJ, Robertson WD, Post R, Smyth SA.

Sci Total Environ. 2019 Aug 2;695:133734. doi: 10.1016/j.scitotenv.2019.133734. [Epub ahead of print]


Increased translocator protein (TSPO) binding throughout neurodevelopment in the perinatal phencyclidine rodent model of schizophrenia.

Lum JS, du Bois TM, Mattner F, Katsifis A, Brown SJ, Huang XF, Newell KA.

Schizophr Res. 2019 Aug 13. pii: S0920-9964(19)30321-4. doi: 10.1016/j.schres.2019.07.041. [Epub ahead of print] No abstract available.


Image processing and analysis methods for the Adolescent Brain Cognitive Development Study.

Hagler DJ Jr, Hatton S, Cornejo MD, Makowski C, Fair DA, Dick AS, Sutherland MT, Casey BJ, Barch DM, Harms MP, Watts R, Bjork JM, Garavan HP, Hilmer L, Pung CJ, Sicat CS, Kuperman J, Bartsch H, Xue F, Heitzeg MM, Laird AR, Trinh TT, Gonzalez R, Tapert SF, Riedel MC, Squeglia LM, Hyde LW, Rosenberg MD, Earl EA, Howlett KD, Baker FC, Soules M, Diaz J, de Leon OR, Thompson WK, Neale MC, Herting M, Sowell ER, Alvarez RP, Hawes SW, Sanchez M, Bodurka J, Breslin FJ, Morris AS, Paulus MP, Simmons WK, Polimeni JR, van der Kouwe A, Nencka AS, Gray KM, Pierpaoli C, Matochik JA, Noronha A, Aklin WM, Conway K, Glantz M, Hoffman E, Little R, Lopez M, Pariyadath V, Weiss SR, Wolff-Hughes DL, DelCarmen-Wiggins R, Feldstein Ewing SW, Miranda-Dominguez O, Nagel BJ, Perrone AJ, Sturgeon DT, Goldstone A, Pfefferbaum A, Pohl KM, Prouty D, Uban K, Bookheimer SY, Dapretto M, Galvan A, Bagot K, Giedd J, Infante MA, Jacobus J, Patrick K, Shilling PD, Desikan R, Li Y, Sugrue L, Banich MT, Friedman N, Hewitt JK, Hopfer C, Sakai J, Tanabe J, Cottler LB, Nixon SJ, Chang L, Cloak C, Ernst T, Reeves G, Kennedy DN, Heeringa S, Peltier S, Schulenberg J, Sripada C, Zucker RA, Iacono WG, Luciana M, Calabro FJ, Clark DB, Lewis DA, Luna B, Schirda C, Brima T, Foxe JJ, Freedman EG, Mruzek DW, Mason MJ, Huber R, McGlade E, Prescot A, Renshaw PF, Yurgelun-Todd DA, Allgaier NA, Dumas JA, Ivanova M, Potter A, Florsheim P, Larson C, Lisdahl K, Charness ME, Fuemmeler B, Hettema JM, Maes HH, Steinberg J, Anokhin AP, Glaser P, Heath AC, Madden PA, Baskin-Sommers A, Constable RT, Grant SJ, Dowling GJ, Brown SA, Jernigan TL, Dale AM.

Neuroimage. 2019 Aug 12:116091. doi: 10.1016/j.neuroimage.2019.116091. [Epub ahead of print]


Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84.

Montgomery MK, Osborne B, Brandon AE, O'Reilly L, Fiveash CE, Brown SHJ, Wilkins BP, Samsudeen A, Yu J, Devanapalli B, Hertzog A, Tolun AA, Kavanagh T, Cooper AA, Mitchell TW, Biden TJ, Smith NJ, Cooney GJ, Turner N.

FASEB J. 2019 Aug 15:fj201900234R. doi: 10.1096/fj.201900234R. [Epub ahead of print]


Risk Factors for Emergency Department Utilization Among Adolescents with Autism Spectrum Disorder.

Liu G, Pearl AM, Kong L, Brown SL, Ba D, Leslie DL, Murray MJ.

J Autism Dev Disord. 2019 Aug 14. doi: 10.1007/s10803-019-04166-y. [Epub ahead of print]


Does Sex Modify the Effect of Endovascular Treatment for Ischemic Stroke?

Chalos V, de Ridder IR, Lingsma HF, Brown S, van Oostenbrugge RJ, Goyal M, Campbell BCV, Muir KW, Guillemin F, Bracard S, White P, Dávalos A, Jovin TG, Hill MD, Mitchell PJ, Demchuk AM, Saver JL, van Zwam WH, Dippel DWJ; HERMES Collaborators.

Stroke. 2019 Sep;50(9):2413-2419. doi: 10.1161/STROKEAHA.118.023743. Epub 2019 Aug 15.


Don't squander sand - save it for sea-level rise.

Brown S, Hanson S.

Nature. 2019 Aug;572(7769):312. doi: 10.1038/d41586-019-02444-4. No abstract available.


Error Disclosure and Apology in Radiology: The Case for Further Dialogue.

Brown SD, Bruno MA, Shyu JY, Eisenberg R, Abujudeh H, Norbash A, Gallagher TH.

Radiology. 2019 Oct;293(1):30-35. doi: 10.1148/radiol.2019190126. Epub 2019 Aug 13. No abstract available.


Fair selection of participants in clinical trials: The challenge to push the envelope further.

Davies JC, Scott S, Dobra R, Brendell R, Brownlee K, Carr SB, Cosgriff R, Simmonds NJ; London Network of Clinical Trials Accelerator Platform sites, Jahan R, Jones A, Matthews J, Brown S, Galono K, Miles K, Pao C, Shafi N, Watson D, Orchard C, Davies G, Pike K, Shah S, Bossley CJ, Fong T, Macedo P, Ruiz G, Waller M, Baker L.

J Cyst Fibros. 2019 Sep;18(5):e48-e50. doi: 10.1016/j.jcf.2019.07.004. Epub 2019 Aug 9. No abstract available.


Rgma-Induced Neo1 Proteolysis Promotes Neural Tube Morphogenesis.

Brown S, Jayachandran P, Negesse M, Olmo V, Vital E, Brewster R.

J Neurosci. 2019 Sep 18;39(38):7465-7484. doi: 10.1523/JNEUROSCI.3262-18.2019. Epub 2019 Aug 9.


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