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Items: 1 to 50 of 101

1.

Nickel-Catalyzed Arylboration of Alkenylarenes: Synthesis of Boron-Substituted Quaternary Carbons and Regiodivergent Reactions.

Chen LA, Lear AR, Gao P, Brown MK.

Angew Chem Int Ed Engl. 2019 Jun 28. doi: 10.1002/anie.201904861. [Epub ahead of print]

PMID:
31250959
2.

Ni-Catalyzed Arylboration of Unactivated Alkenes: Scope and Mechanistic Studies.

Sardini SR, Lambright AL, Trammel GL, Omer HM, Liu P, Brown MK.

J Am Chem Soc. 2019 Jun 12;141(23):9391-9400. doi: 10.1021/jacs.9b03991. Epub 2019 Jun 4.

PMID:
31184148
3.

(Hetero)arylboration of alkynes: a strategy for the synthesis of α,α-bis(hetero)arylketones.

Huang Y, Bergmann AM, Brown MK.

Org Biomol Chem. 2019 Jun 18;17(24):5913-5915. doi: 10.1039/c9ob00961b.

PMID:
31165124
4.

Recent advances in the synthesis of gem-dimethylcyclobutane natural products.

Hancock EN, Wiest JM, Brown MK.

Nat Prod Rep. 2019 Mar 11. doi: 10.1039/c8np00083b. [Epub ahead of print]

PMID:
30855044
5.

Synthesis of Bisheteroarylalkanes by Heteroarylboration: Development and Application of a Pyridylidene-Copper Complex.

Huang Y, Brown MK.

Angew Chem Int Ed Engl. 2019 Apr 23;58(18):6048-6052. doi: 10.1002/anie.201902238. Epub 2019 Mar 27.

PMID:
30838739
6.

Impact of a Structured Weight Management Program on Worker Productivity.

Iyengar JJ, Miller NM, Ajluni N, Kraftson AT, Nay CK, Brown MK, Rothberg AE.

J Occup Environ Med. 2019 Feb;61(2):148-152. doi: 10.1097/JOM.0000000000001504.

PMID:
30730855
7.

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.

Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, Dorjsuren D, Eastman RT, Huang R, Iannotti MJ, Karavadhi S, Klumpp-Thomas C, Roth JS, Sakamuru S, Sun W, Titus SA, Yasgar A, Zhang YQ, Zhao J, Andrade RB, Brown MK, Burns NZ, Cha JK, Mevers EE, Clardy J, Clement JA, Crooks PA, Cuny GD, Ganor J, Moreno J, Morrill LA, Picazo E, Susick RB, Garg NK, Goess BC, Grossman RB, Hughes CC, Johnston JN, Joullie MM, Kinghorn AD, Kingston DGI, Krische MJ, Kwon O, Maimone TJ, Majumdar S, Maloney KN, Mohamed E, Murphy BT, Nagorny P, Olson DE, Overman LE, Brown LE, Snyder JK, Porco JA Jr, Rivas F, Ross SA, Sarpong R, Sharma I, Shaw JT, Xu Z, Shen B, Shi W, Stephenson CRJ, Verano AL, Tan DS, Tang Y, Taylor RE, Thomson RJ, Vosburg DA, Wu J, Wuest WM, Zakarian A, Zhang Y, Ren T, Zuo Z, Inglese J, Michael S, Simeonov A, Zheng W, Shinn P, Jadhav A, Boxer MB, Hall MD, Xia M, Guha R, Rohde JM.

ACS Cent Sci. 2018 Dec 26;4(12):1727-1741. doi: 10.1021/acscentsci.8b00747. Epub 2018 Dec 5.

8.

Catalyst-Controlled 1,2- and 1,1-Arylboration of α-Alkyl Alkenyl Arenes.

Bergmann AM, Dorn SK, Smith KB, Logan KM, Brown MK.

Angew Chem Int Ed Engl. 2019 Feb 4;58(6):1719-1723. doi: 10.1002/anie.201812533. Epub 2019 Jan 9.

PMID:
30521697
9.

Allenoates in Enantioselective [2+2] Cycloadditions: From a Mechanistic Curiosity to a Stereospecific Transformation.

Wiest JM, Conner ML, Brown MK.

J Am Chem Soc. 2018 Nov 21;140(46):15943-15949. doi: 10.1021/jacs.8b10008. Epub 2018 Nov 5.

PMID:
30394735
10.

Nickel-Catalyzed Stereoselective Diarylation of Alkenylarenes.

Gao P, Chen LA, Brown MK.

J Am Chem Soc. 2018 Aug 29;140(34):10653-10657. doi: 10.1021/jacs.8b05680. Epub 2018 Aug 20.

PMID:
30125098
11.

Circadian Health and Light: A Report on the National Heart, Lung, and Blood Institute's Workshop.

Mason IC, Boubekri M, Figueiro MG, Hasler BP, Hattar S, Hill SM, Nelson RJ, Sharkey KM, Wright KP, Boyd WA, Brown MK, Laposky AD, Twery MJ, Zee PC.

J Biol Rhythms. 2018 Oct;33(5):451-457. doi: 10.1177/0748730418789506. Epub 2018 Jul 23.

PMID:
30033850
12.

Early prediction of a significant patent ductus arteriosus in infants <32 weeks gestational age.

Katheria V, Poeltler DM, Brown MK, Hassen KO, Patel D, Rich W, Finer NN, Katheria AC.

J Neonatal Perinatal Med. 2018;11(3):265-271. doi: 10.3233/NPM-1771.

PMID:
29843271
13.

Impact of a neuro-intensive care service for newborns.

Harbert MJ, Sey R, Arnell K, Salinda L, Brown MK, Lazarus D, Poeltler DM, Wozniak PR, Rasmussen MR.

J Neonatal Perinatal Med. 2018;11(2):173-178. doi: 10.3233/NPM-181751.

PMID:
29843267
14.

Copper-catalyzed cross-coupling of aryl-, primary alkyl-, and secondary alkylboranes with heteroaryl bromides.

Bergmann AM, Oldham AM, You W, Brown MK.

Chem Commun (Camb). 2018 May 22;54(42):5381-5384. doi: 10.1039/c8cc03145b.

PMID:
29745398
15.

Copper-Catalyzed Heteroarylboration of 1,3-Dienes with 3-Bromopyridines: A cine Substitution.

Smith KB, Huang Y, Brown MK.

Angew Chem Int Ed Engl. 2018 May 22;57(21):6146-6149. doi: 10.1002/anie.201801139. Epub 2018 Apr 26.

16.

The Neu-Prem Trial: Neuromonitoring of Brains of Infants Born Preterm During Resuscitation-A Prospective Observational Cohort Study.

Katheria AC, Harbert MJ, Nagaraj SB, Arnell K, Poeltler DM, Brown MK, Rich W, Hassen KO, Finer N.

J Pediatr. 2018 Jul;198:209-213.e3. doi: 10.1016/j.jpeds.2018.02.065. Epub 2018 Apr 18.

PMID:
29680471
17.

Incidence of Hypocapnia, Hypercapnia, and Acidosis and the Associated Risk of Adverse Events in Preterm Neonates.

Brown MK, Poeltler DM, Hassen KO, Lazarus DV, Brown VK, Stout JJ, Rich WD, Katheria AC.

Respir Care. 2018 Aug;63(8):943-949. doi: 10.4187/respcare.05801. Epub 2018 Apr 3.

PMID:
29615483
18.

Synthesis of (-)-Hebelophyllene E: An Entry to Geminal Dimethyl-Cyclobutanes by [2+2] Cycloaddition of Alkenes and Allenoates.

Wiest JM, Conner ML, Brown MK.

Angew Chem Int Ed Engl. 2018 Apr 16;57(17):4647-4651. doi: 10.1002/anie.201801110. Epub 2018 Mar 24.

19.

Nickel-Catalyzed Stereoselective Arylboration of Unactivated Alkenes.

Logan KM, Sardini SR, White SD, Brown MK.

J Am Chem Soc. 2018 Jan 10;140(1):159-162. doi: 10.1021/jacs.7b12160. Epub 2017 Dec 22.

20.

Design, optimisation and preliminary validation of a human specific loop-mediated amplification assay for the rapid detection of human DNA at forensic crime scenes.

Hird HJ, Brown MK.

Sci Justice. 2017 Nov;57(6):409-414. doi: 10.1016/j.scijus.2017.08.001. Epub 2017 Aug 3.

PMID:
29173453
21.

Synthesis of ent-[3]-Ladderanol: Development and Application of Intramolecular Chirality Transfer [2+2] Cycloadditions of Allenic Ketones and Alkenes.

Line NJ, Witherspoon BP, Hancock EN, Brown MK.

J Am Chem Soc. 2017 Oct 18;139(41):14392-14395. doi: 10.1021/jacs.7b09844. Epub 2017 Oct 6.

22.

Copper-Catalyzed Borylacylation of Activated Alkenes with Acid Chlorides.

Huang Y, Smith KB, Brown MK.

Angew Chem Int Ed Engl. 2017 Oct 16;56(43):13314-13318. doi: 10.1002/anie.201707323. Epub 2017 Sep 18.

23.

Catalyst Controlled Regiodivergent Arylboration of Dienes.

Sardini SR, Brown MK.

J Am Chem Soc. 2017 Jul 26;139(29):9823-9826. doi: 10.1021/jacs.7b05477. Epub 2017 Jul 12.

24.

Intramolecular Chirality Transfer [2 + 2] Cycloadditions of Allenoates and Alkenes.

Xu Y, Hong YJ, Tantillo DJ, Brown MK.

Org Lett. 2017 Jul 21;19(14):3703-3706. doi: 10.1021/acs.orglett.7b01420. Epub 2017 Jul 7.

25.

Regioselective Arylboration of Isoprene and Its Derivatives by Pd/Cu Cooperative Catalysis.

Smith KB, Brown MK.

J Am Chem Soc. 2017 Jun 14;139(23):7721-7724. doi: 10.1021/jacs.7b04024. Epub 2017 Jun 5.

26.

Reduced Sleep During Social Isolation Leads to Cellular Stress and Induction of the Unfolded Protein Response.

Brown MK, Strus E, Naidoo N.

Sleep. 2017 Jul 1;40(7). doi: 10.1093/sleep/zsx095.

27.

Delayed Cord Clamping in Newborns Born at Term at Risk for Resuscitation: A Feasibility Randomized Clinical Trial.

Katheria AC, Brown MK, Faksh A, Hassen KO, Rich W, Lazarus D, Steen J, Daneshmand SS, Finer NN.

J Pediatr. 2017 Aug;187:313-317.e1. doi: 10.1016/j.jpeds.2017.04.033. Epub 2017 May 16.

PMID:
28526223
28.

Hemodynamic effects of sodium bicarbonate administration.

Katheria AC, Brown MK, Hassan K, Poeltler DM, Patel DA, Brown VK, Sauberan JB.

J Perinatol. 2017 May;37(5):518-520. doi: 10.1038/jp.2016.258. Epub 2017 Feb 16.

PMID:
28206993
29.

Providing a Placental Transfusion in Newborns Who Need Resuscitation.

Katheria AC, Brown MK, Rich W, Arnell K.

Front Pediatr. 2017 Jan 25;5:1. doi: 10.3389/fped.2017.00001. eCollection 2017. Review.

30.

Catalytic Enantioselective Arylboration of Alkenylarenes.

Logan KM, Brown MK.

Angew Chem Int Ed Engl. 2017 Jan 16;56(3):851-855. doi: 10.1002/anie.201609844. Epub 2016 Dec 21.

31.

An unexpected Lewis acid catalyzed Diels-Alder cycloaddition of aryl allenes and acrylates.

Conner ML, Brown MK.

Tetrahedron. 2016 Jun 30;72(26):3759-3765. Epub 2016 Feb 18.

32.

Synthesis of 1,3-Substituted Cyclobutanes by Allenoate-Alkene [2 + 2] Cycloaddition.

Conner ML, Brown MK.

J Org Chem. 2016 Sep 2;81(17):8050-60. doi: 10.1021/acs.joc.6b01446. Epub 2016 Aug 25.

33.

Defining the Clinical Significance of Alloscardovia omnincolens in the Urinary Tract.

Brown MK, Forbes BA, Stitley K, Doern CD.

J Clin Microbiol. 2016 Jun;54(6):1552-1556. doi: 10.1128/JCM.03084-15. Epub 2016 Apr 6.

34.

Resistance of Colorimetric Carbon Dioxide Detectors Commonly Utilized in Neonates.

Brown MK, Lazarus DV, Gonzales SR, Rich WD, Wozniak MJ, Poeltler DM, Katheria AC.

Respir Care. 2016 Aug;61(8):1003-7. doi: 10.4187/respcare.04507. Epub 2016 Apr 5.

35.

Collaborative Total Synthesis: Routes to (±)-Hippolachnin A Enabled by Quadricyclane Cycloaddition and Late-Stage C-H Oxidation.

McCallum ME, Rasik CM, Wood JL, Brown MK.

J Am Chem Soc. 2016 Feb 24;138(7):2437-42. doi: 10.1021/jacs.5b13586. Epub 2016 Feb 9.

36.

Catalytic Enantioselective Diarylation of Alkenes.

You W, Brown MK.

J Am Chem Soc. 2015 Nov 25;137(46):14578-81. doi: 10.1021/jacs.5b10176. Epub 2015 Nov 13.

PMID:
26565926
37.

Lewis acid-promoted [2 + 2] cycloadditions of alkenes with aryl ketenes.

Rigsbee EM, Zhou C, Rasik CM, Spitz AZ, Nichols AJ, Brown MK.

Org Biomol Chem. 2016 Jun 28;14(24):5477-80. doi: 10.1039/c5ob01837d. Epub 2015 Sep 30.

38.

Cyclobutane and cyclobutene synthesis: catalytic enantioselective [2+2] cycloadditions.

Xu Y, Conner ML, Brown MK.

Angew Chem Int Ed Engl. 2015 Oct 5;54(41):11918-28. doi: 10.1002/anie.201502815. Epub 2015 Sep 2.

PMID:
26333192
39.

Catalytic enantioselective allenoate-alkene [2 + 2] cycloadditions.

Conner ML, Xu Y, Brown MK.

J Am Chem Soc. 2015 Mar 18;137(10):3482-5. doi: 10.1021/jacs.5b00563. Epub 2015 Mar 10.

PMID:
25756948
40.

Copper/palladium synergistic catalysis for the syn- and anti-selective carboboration of alkenes.

Logan KM, Smith KB, Brown MK.

Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5228-31. doi: 10.1002/anie.201500396. Epub 2015 Feb 27.

PMID:
25727074
41.

Total synthesis of gracilioether F: development and application of lewis Acid promoted ketene-alkene [2+2] cycloadditions and late-stage C-H oxidation.

Rasik CM, Brown MK.

Angew Chem Int Ed Engl. 2014 Dec 22;53(52):14522-6. doi: 10.1002/anie.201408055. Epub 2014 Oct 30.

PMID:
25359632
42.

Diarylation of alkenes by a Cu-catalyzed migratory insertion/cross-coupling cascade.

You W, Brown MK.

J Am Chem Soc. 2014 Oct 22;136(42):14730-3. doi: 10.1021/ja509056j. Epub 2014 Oct 10.

PMID:
25303225
43.

Origins of diastereoselectivity in Lewis acid promoted ketene-alkene [2 + 2] cycloadditions.

Rasik CM, Hong YJ, Tantillo DJ, Brown MK.

Org Lett. 2014 Oct 3;16(19):5168-71. doi: 10.1021/ol5025184. Epub 2014 Sep 17.

PMID:
25230201
44.

Alkene carboboration enabled by synergistic catalysis.

Smith KB, Logan KM, You W, Brown MK.

Chemistry. 2014 Sep 15;20(38):12032-6. doi: 10.1002/chem.201404310. Epub 2014 Aug 11.

PMID:
25113669
45.

Rapid detection and differentiation of human noroviruses using RT-PCR coupled to electrospray ionization mass spectrometry.

Hellberg RS, Li F, Sampath R, Yasuda IJ, Carolan HE, Wolfe JM, Brown MK, Alexander RC, Williams-Hill DM, Martin WB.

Food Microbiol. 2014 Dec;44:71-80. doi: 10.1016/j.fm.2014.05.017. Epub 2014 Jun 3.

PMID:
25084648
46.

Copper-catalyzed cross-coupling of boronic esters with aryl iodides and application to the carboboration of alkynes and allenes.

Zhou Y, You W, Smith KB, Brown MK.

Angew Chem Int Ed Engl. 2014 Mar 24;53(13):3475-9.

PMID:
24677502
47.

Aging induced endoplasmic reticulum stress alters sleep and sleep homeostasis.

Brown MK, Chan MT, Zimmerman JE, Pack AI, Jackson NE, Naidoo N.

Neurobiol Aging. 2014 Jun;35(6):1431-41. doi: 10.1016/j.neurobiolaging.2013.12.005. Epub 2013 Dec 14.

48.

Centromere binding and a conserved role in chromosome stability for SUMO-dependent ubiquitin ligases.

van de Pasch LA, Miles AJ, Nijenhuis W, Brabers NA, van Leenen D, Lijnzaad P, Brown MK, Ouellet J, Barral Y, Kops GJ, Holstege FC.

PLoS One. 2013 Jun 13;8(6):e65628. doi: 10.1371/journal.pone.0065628. Print 2013.

49.

The acid phosphatase test two minute cut-off: an insufficient time to detect some semen stains.

Redhead P, Brown MK.

Sci Justice. 2013 Jun;53(2):187-91. doi: 10.1016/j.scijus.2012.09.004. Epub 2012 Oct 4.

PMID:
23601727
50.

Stereoselective synthesis of all-carbon tetrasubstituted alkenes from in situ generated ketenes and organometallic reagents.

You W, Li Y, Brown MK.

Org Lett. 2013 Apr 5;15(7):1610-3. doi: 10.1021/ol400392r. Epub 2013 Mar 12.

PMID:
23480662

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