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Items: 1 to 50 of 936

1.

Airway host-microbiome interactions in chronic obstructive pulmonary disease.

Wang Z, Maschera B, Lea S, Kolsum U, Michalovich D, Van Horn S, Traini C, Brown JR, Hessel EM, Singh D.

Respir Res. 2019 Jun 6;20(1):113. doi: 10.1186/s12931-019-1085-z.

2.

Growth dynamics in naturally progressing chronic lymphocytic leukaemia.

Gruber M, Bozic I, Leshchiner I, Livitz D, Stevenson K, Rassenti L, Rosebrock D, Taylor-Weiner A, Olive O, Goyetche R, Fernandes SM, Sun J, Stewart C, Wong A, Cibulskis C, Zhang W, Reiter JG, Gerold JM, Gribben JG, Rai KR, Keating MJ, Brown JR, Neuberg D, Kipps TJ, Nowak MA, Getz G, Wu CJ.

Nature. 2019 May 29. doi: 10.1038/s41586-019-1252-x. [Epub ahead of print]

PMID:
31142838
3.

Acalabrutinib monotherapy in patients with chronic lymphocytic leukemia who are intolerant to ibrutinib.

Awan FT, Schuh A, Brown JR, Furman RR, Pagel JM, Hillmen P, Stephens DM, Woyach J, Bibikova E, Charuworn P, Frigault MM, Hamdy A, Izumi R, Linghu B, Patel P, Wang MH, Byrd JC.

Blood Adv. 2019 May 14;3(9):1553-1562. doi: 10.1182/bloodadvances.2018030007.

4.

Phase 1 study of lenalidomide, bendamustine, and rituximab in previously untreated patients with chronic lymphocytic leukemia.

Soumerai JD, Davids MS, Werner L, Fisher DC, Armand P, Amrein PC, Neuberg D, Hochberg EP, Brown JR, Abramson JS.

Leuk Lymphoma. 2019 May 10:1-8. doi: 10.1080/10428194.2019.1608533. [Epub ahead of print]

PMID:
31074316
5.

Efficacy results of a phase 2 trial of first-line idelalisib plus ofatumumab in chronic lymphocytic leukemia.

Lampson BL, Kim HT, Davids MS, Abramson JS, Freedman AS, Jacobson CA, Armand PA, Joyce RM, Arnason JE, Rassenti LZ, Kipps TJ, Fein J, Fernandes SM, Hanna JR, Fisher DC, Brown JR.

Blood Adv. 2019 Apr 9;3(7):1167-1174. doi: 10.1182/bloodadvances.2018030221.

6.

The opportunity cost of walking away in the spatial iterated prisoner's dilemma.

Premo LS, Brown JR.

Theor Popul Biol. 2019 Jun;127:40-48. doi: 10.1016/j.tpb.2019.03.004. Epub 2019 Apr 1.

PMID:
30946861
7.

Biomarkers associated with 30-day readmission and mortality after pediatric congenital heart surgery.

Parker DM, Everett AD, Stabler ME, Vricella L, Jacobs ML, Jacobs JP, Thiessen-Philbrook H, Parikh CR, Brown JR.

J Card Surg. 2019 May;34(5):329-336. doi: 10.1111/jocs.14038. Epub 2019 Apr 3.

PMID:
30942505
8.

Claims-based surveillance for reintervention after endovascular aneurysm repair among non-Medicare patients.

Columbo JA, Sedrakyan A, Mao J, Hoel AW, Trooboff SW, Kang R, Brown JR, Goodney PP.

J Vasc Surg. 2019 Mar 25. pii: S0741-5214(19)30066-7. doi: 10.1016/j.jvs.2018.11.031. [Epub ahead of print]

PMID:
30922744
9.

Perceived risk for cancer progression and psychological status in chronic lymphocytic leukemia patients: CALGB 70603 (Alliance).

Deshields TL, Dueck AC, Rogers K, Brown JR, Shanafelt T, Mintzer D, Byrd JC.

Leuk Lymphoma. 2019 Mar 27:1-4. doi: 10.1080/10428194.2019.1594218. [Epub ahead of print] No abstract available.

PMID:
30916608
10.

Are Urinary Biomarkers Better Than Acute Kidney Injury Duration for Predicting Readmission?

Brown JR, Thiessen-Philbrook H, Goodrich CA, Bohm AR, Alam SS, Coca SG, McArthur E, Garg AX, Parikh CR.

Ann Thorac Surg. 2019 Jun;107(6):1699-1705. doi: 10.1016/j.athoracsur.2019.02.005. Epub 2019 Mar 14.

PMID:
30880140
11.

Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity.

Tran TTT, Cousin FJ, Lynch DB, Menon R, Brulc J, Brown JR, O'Herlihy E, Butto LF, Power K, Jeffery IB, O'Connor EM, O'Toole PW.

Microbiome. 2019 Mar 13;7(1):39. doi: 10.1186/s40168-019-0654-1.

12.

Long-term follow-up of the RESONATE phase 3 trial of ibrutinib vs ofatumumab.

Byrd JC, Hillmen P, O'Brien S, Barrientos JC, Reddy NM, Coutre S, Tam CS, Mulligan SP, Jaeger U, Barr PM, Furman RR, Kipps TJ, Thornton P, Moreno C, Montillo M, Pagel JM, Burger JA, Woyach JA, Dai S, Vezan R, James DF, Brown JR.

Blood. 2019 May 9;133(19):2031-2042. doi: 10.1182/blood-2018-08-870238. Epub 2019 Mar 6.

PMID:
30842083
13.

Outcomes with ibrutinib by line of therapy and post-ibrutinib discontinuation in patients with chronic lymphocytic leukemia: Phase 3 analysis.

O'Brien SM, Byrd JC, Hillmen P, Coutre S, Brown JR, Barr PM, Barrientos JC, Devereux S, Robak T, Reddy NM, Kipps TJ, Tedeschi A, Cymbalista F, Ghia P, Chang S, Ninomoto J, James DF, Burger JA.

Am J Hematol. 2019 May;94(5):554-562. doi: 10.1002/ajh.25436. Epub 2019 Mar 8.

PMID:
30767298
14.

Biomarkers for the prediction of cardiac readmission.

Parker DM, Brown JR.

Biomark Med. 2019 Feb;13(2):55-58. doi: 10.2217/bmm-2018-0381. Epub 2019 Jan 23. No abstract available.

15.

Durable remissions with obinutuzumab-based chemoimmunotherapy: long-term follow-up of the phase 1b GALTON trial in CLL.

Brown JR, O'Brien S, Kingsley CD, Eradat H, Pagel JM, Hirata J, McIver T, Morariu-Zamfir R, Kipps TJ.

Blood. 2019 Feb 28;133(9):990-992. doi: 10.1182/blood-2018-06-857714. Epub 2018 Dec 28. No abstract available.

PMID:
30593446
16.

Inconsistent Inferences.

Ramkumar N, Brown JR.

Circ Cardiovasc Qual Outcomes. 2018 Dec;11(12):e005235. doi: 10.1161/CIRCOUTCOMES.118.005235. No abstract available. Erratum in: Circ Cardiovasc Qual Outcomes. 2019 Feb;12(2):e000053.

PMID:
30562076
17.

Umbralisib in combination with ibrutinib in patients with relapsed or refractory chronic lymphocytic leukaemia or mantle cell lymphoma: a multicentre phase 1-1b study.

Davids MS, Kim HT, Nicotra A, Savell A, Francoeur K, Hellman JM, Bazemore J, Miskin HP, Sportelli P, Stampleman L, Maegawa R, Rueter J, Boruchov AM, Arnason JE, Jacobson CA, Jacobsen ED, Fisher DC, Brown JR; Blood Cancer Research Partnership of the Leukemia and Lymphoma Society.

Lancet Haematol. 2019 Jan;6(1):e38-e47. doi: 10.1016/S2352-3026(18)30196-0. Epub 2018 Dec 14.

PMID:
30558987
18.

DUO delivers for duvelisib.

Brown JR.

Blood. 2018 Dec 6;132(23):2422-2424. doi: 10.1182/blood-2018-10-879650. No abstract available.

19.

Ibrutinib: searching for a partner drug.

Kater AP, Brown JR.

Lancet Oncol. 2019 Jan;20(1):3-5. doi: 10.1016/S1470-2045(18)30861-1. Epub 2018 Dec 3. No abstract available.

PMID:
30522966
20.

MYD88 L265P mutations identify a prognostic gene expression signature and a pathway for targeted inhibition in CLL.

Improgo MR, Tesar B, Klitgaard JL, Magori-Cohen R, Yu L, Kasar S, Chaudhary D, Miao W, Fernandes SM, Hoang K, Westlin WF, Kim HT, Brown JR.

Br J Haematol. 2019 Mar;184(6):925-936. doi: 10.1111/bjh.15714. Epub 2018 Dec 9.

PMID:
30537114
21.

Incidence of and risk factors for major haemorrhage in patients treated with ibrutinib: An integrated analysis.

Brown JR, Moslehi J, Ewer MS, O'Brien SM, Ghia P, Cymbalista F, Shanafelt TD, Fraser G, Rule S, Coutre SE, Dilhuydy MS, Cramer P, Jaeger U, Dreyling M, Byrd JC, Treon S, Liu EY, Chang S, Bista A, Vempati R, Boornazian L, Valentino R, Reddy V, Mahler M, Yang H, Graef T, Burger JA.

Br J Haematol. 2019 Feb;184(4):558-569. doi: 10.1111/bjh.15690. Epub 2018 Dec 2.

PMID:
30506764
22.

Relapsed CLL: sequencing, combinations, and novel agents.

Brown JR.

Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):248-255. doi: 10.1182/asheducation-2018.1.248. Review.

PMID:
30504318
23.

Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia.

Ott CJ, Federation AJ, Schwartz LS, Kasar S, Klitgaard JL, Lenci R, Li Q, Lawlor M, Fernandes SM, Souza A, Polaski D, Gadi D, Freedman ML, Brown JR, Bradner JE.

Cancer Cell. 2018 Dec 10;34(6):982-995.e7. doi: 10.1016/j.ccell.2018.11.001. Epub 2018 Nov 29.

PMID:
30503705
24.

Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL.

Woyach JA, Ruppert AS, Heerema NA, Zhao W, Booth AM, Ding W, Bartlett NL, Brander DM, Barr PM, Rogers KA, Parikh SA, Coutre S, Hurria A, Brown JR, Lozanski G, Blachly JS, Ozer HG, Major-Elechi B, Fruth B, Nattam S, Larson RA, Erba H, Litzow M, Owen C, Kuzma C, Abramson JS, Little RF, Smith SE, Stone RM, Mandrekar SJ, Byrd JC.

N Engl J Med. 2018 Dec 27;379(26):2517-2528. doi: 10.1056/NEJMoa1812836. Epub 2018 Dec 1.

PMID:
30501481
25.

sST2 as a novel biomarker for the prediction of in-hospital mortality after coronary artery bypass grafting.

Stabler ME, Rezaee ME, Parker DM, MacKenzie TA, Bohm AR, DiScipio AW, Malenka DJ, Brown JR.

Biomarkers. 2019 May;24(3):268-276. doi: 10.1080/1354750X.2018.1556338. Epub 2019 Jan 11.

PMID:
30512977
26.

PI3K p110δ inactivation antagonizes chronic lymphocytic leukemia and reverses T cell immune suppression.

Dong S, Harrington BK, Hu EY, Greene JT, Lehman AM, Tran M, Wasmuth RL, Long M, Muthusamy N, Brown JR, Johnson AJ, Byrd JC.

J Clin Invest. 2019 Jan 2;129(1):122-136. doi: 10.1172/JCI99386. Epub 2018 Nov 19.

27.

Correction to: Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia.

Bucciol G, Moens L, Payne K, Wollants E, Mekahli D, Levtchenko E, Vermeulen F, Tousseyn T, Gray P, Ma CS, Tangye SG, Van Ranst M, Brown JR, Breuer J, Meyts I.

J Clin Immunol. 2018 Nov;38(8):938-939. doi: 10.1007/s10875-018-0570-3.

PMID:
30430354
28.

Artificial intelligence in gastrointestinal endoscopy: The future is almost here.

Alagappan M, Brown JRG, Mori Y, Berzin TM.

World J Gastrointest Endosc. 2018 Oct 16;10(10):239-249. doi: 10.4253/wjge.v10.i10.239. Review.

29.

Elevated preoperative Galectin-3 is associated with acute kidney injury after cardiac surgery.

Wyler von Ballmoos M, Likosky DS, Rezaee M, Lobdell K, Alam S, Parker D, Owens S, Thiessen-Philbrook H, MacKenzie T, Brown JR.

BMC Nephrol. 2018 Oct 20;19(1):280. doi: 10.1186/s12882-018-1093-0.

30.

Ofatumumab plus high dose methylprednisolone followed by ofatumumab plus alemtuzumab to achieve maximal cytoreduction prior to allogeneic transplantation for 17p deleted or TP53 mutated chronic lymphocytic leukemia.

Davids MS, Kim HT, Yu L, De Maeyer G, McDonough M, Vartanov AR, Langey R, Fernandes SM, Hellman JM, Francoeur K, Arnason J, Jacobsen ED, LaCasce AS, Fisher DC, Brown JR.

Leuk Lymphoma. 2019 May;60(5):1312-1315. doi: 10.1080/10428194.2018.1519814. Epub 2018 Oct 15.

PMID:
30322319
31.

Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia.

Bucciol G, Moens L, Payne K, Wollants E, Mekahli D, Levtchenko E, Vermeulen F, Tousseyn T, Gray P, Ma CS, Tangye SG, Van Ranst M, Brown JR, Breuer J, Meyts I.

J Clin Immunol. 2018 Oct;38(7):748-752. doi: 10.1007/s10875-018-0558-z. Epub 2018 Oct 11. No abstract available. Erratum in: J Clin Immunol. 2018 Nov;38(8):938-939.

PMID:
30311057
32.

Improvement in Parameters of Hematologic and Immunologic Function and Patient Well-being in the Phase III RESONATE Study of Ibrutinib Versus Ofatumumab in Patients With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Barrientos JC, O'Brien S, Brown JR, Kay NE, Reddy NM, Coutre S, Tam C, Mulligan S, Jaeger U, Devereux S, Pocock C, Robak T, Schuster SJ, Schuh A, Gill D, Bloor A, Dearden C, Moreno C, Cull G, Hamblin M, Jones JA, Eckert K, Solman IG, Suzuki S, Hsu E, James DF, Byrd JC, Hillmen P.

Clin Lymphoma Myeloma Leuk. 2018 Dec;18(12):803-813.e7. doi: 10.1016/j.clml.2018.08.007. Epub 2018 Aug 18.

33.

Changes in microbiota composition, bile and fatty acid metabolism, in successful faecal microbiota transplantation for Clostridioides difficile infection.

Brown JR, Flemer B, Joyce SA, Zulquernain A, Sheehan D, Shanahan F, O'Toole PW.

BMC Gastroenterol. 2018 Aug 28;18(1):131. doi: 10.1186/s12876-018-0860-5.

34.

Microbial Translocation Does Not Drive Immune Activation in Ugandan Children Infected With HIV.

Fitzgerald FC, Lhomme E, Harris K, Kenny J, Doyle R, Kityo C, Shaw LP, Abongomera G, Musiime V, Cook A, Brown JR, Brooks A, Owen-Powell E, Gibb DM, Prendergast AJ, Sarah Walker A, Thiebaut R, Klein N; CHAPAS-3 Trial Team .

J Infect Dis. 2019 Jan 1;219(1):89-100. doi: 10.1093/infdis/jiy495.

35.

Utility of Biomarkers to Improve Prediction of Readmission or Mortality After Cardiac Surgery.

Brown JR, Jacobs JP, Alam SS, Thiessen-Philbrook H, Everett A, Likosky DS, Lobdell K, Wyler von Ballmoos MC, Parker DM, Garg AX, Mackenzie T, Jacobs ML, Parikh CR.

Ann Thorac Surg. 2018 Nov;106(5):1294-1301. doi: 10.1016/j.athoracsur.2018.06.052. Epub 2018 Aug 4.

PMID:
30086283
36.

Vigilance for ibrutinib-associated ventricular arrhythmias: rare but be aware.

Tam CS, Brown JR.

Leuk Lymphoma. 2018 Dec;59(12):2767-2768. doi: 10.1080/10428194.2018.1482546. Epub 2018 Jul 22. No abstract available.

PMID:
30032684
37.

Left Off the Route: A Qualitative Examination of Urban Bus Drivers Wanting to be Players in the Bully Prevention Solution.

Brown JR, Karikari I, Abraham S, Akakpo T.

J Interpers Violence. 2018 Jul 1:886260518787204. doi: 10.1177/0886260518787204. [Epub ahead of print]

PMID:
29991322
38.

High Viral Diversity and Mixed Infections in Cerebral Spinal Fluid From Cases of Varicella Zoster Virus Encephalitis.

Depledge DP, Cudini J, Kundu S, Atkinson C, Brown JR, Haque T, Houldcroft CJ, Koay ES, McGill F, Milne R, Whitfield T, Tang JW, Underhill G, Bergstrom T, Norberg P, Goldstein R, Solomon T, Breuer J.

J Infect Dis. 2018 Oct 5;218(10):1592-1601. doi: 10.1093/infdis/jiy358.

39.

Predictive Ability of Novel Cardiac Biomarkers ST2, Galectin-3, and NT-ProBNP Before Cardiac Surgery.

Polineni S, Parker DM, Alam SS, Thiessen-Philbrook H, McArthur E, DiScipio AW, Malenka DJ, Parikh CR, Garg AX, Brown JR.

J Am Heart Assoc. 2018 Jul 7;7(14). pii: e008371. doi: 10.1161/JAHA.117.008371.

40.

Still a role for second-line chemoimmunotherapy in chronic lymphocytic leukemia?

Brown JR.

Haematologica. 2018 Jul;103(7):1096-1098. doi: 10.3324/haematol.2018.196014. No abstract available.

41.

Use of Whole-Genome Sequencing of Adenovirus in Immunocompromised Pediatric Patients to Identify Nosocomial Transmission and Mixed-Genotype Infection.

Houldcroft CJ, Roy S, Morfopoulou S, Margetts BK, Depledge DP, Cudini J, Shah D, Brown JR, Romero EY, Williams R, Cloutman-Green E, Rao K, Standing JF, Hartley JC, Breuer J.

J Infect Dis. 2018 Sep 8;218(8):1261-1271. doi: 10.1093/infdis/jiy323.

PMID:
29917114
42.

The Association Between Novel Biomarkers and 1-Year Readmission or Mortality After Cardiac Surgery.

Jacobs JP, Alam SS, Owens SL, Parker DM, Rezaee M, Likosky DS, Shahian DM, Jacobs ML, Thiessen-Philbrook H, Wyler von Ballmoos M, Lobdell K, MacKenzie T, Everett AD, Parikh CR, Brown JR.

Ann Thorac Surg. 2018 Oct;106(4):1122-1128. doi: 10.1016/j.athoracsur.2018.04.084. Epub 2018 Jun 1.

PMID:
29864407
43.

Pityriasis rubra pilaris-like erythroderma secondary to phosphoinositide 3-kinase inhibition.

Dewan AK, Sowerby L, Jadeja S, Lian C, Wen P, Brown JR, Fisher DC, LeBoeuf NR.

Clin Exp Dermatol. 2018 Dec;43(8):890-894. doi: 10.1111/ced.13608. Epub 2018 May 30.

PMID:
29851132
44.

Norovirus Transmission Dynamics in a Pediatric Hospital Using Full Genome Sequences.

Brown JR, Roy S, Shah D, Williams CA, Williams R, Dunn H, Hartley J, Harris K, Breuer J.

Clin Infect Dis. 2019 Jan 7;68(2):222-228. doi: 10.1093/cid/ciy438.

45.

Preoperative serum ST2 level predicts acute kidney injury after adult cardiac surgery.

Lobdell KW, Parker DM, Likosky DS, Rezaee M, Wyler von Ballmoos M, Alam SS, Owens S, Thiessen-Philbrook H, MacKenzie T, Brown JR.

J Thorac Cardiovasc Surg. 2018 Sep;156(3):1114-1123.e2. doi: 10.1016/j.jtcvs.2018.03.149. Epub 2018 Apr 11.

PMID:
29759735
46.

Impact of Infant Supraglottoplasty on Quality of Life.

Vandjelovic ND, Brown JR, Traboulsi HT, Thottam PJ.

Otolaryngol Head Neck Surg. 2018 Sep;159(3):564-571. doi: 10.1177/0194599818775091. Epub 2018 May 15.

PMID:
29759025
47.

Ibrutinib: coming of age?

Brown JR.

Blood. 2018 Apr 26;131(17):1880-1882. doi: 10.1182/blood-2018-02-832071. No abstract available.

48.

Ion Correlation Effects in Salt-Doped Block Copolymers.

Brown JR, Seo Y, Hall LM.

Phys Rev Lett. 2018 Mar 23;120(12):127801. doi: 10.1103/PhysRevLett.120.127801.

PMID:
29694088
49.

Voxtalisib (XL765) in patients with relapsed or refractory non-Hodgkin lymphoma or chronic lymphocytic leukaemia: an open-label, phase 2 trial.

Brown JR, Hamadani M, Hayslip J, Janssens A, Wagner-Johnston N, Ottmann O, Arnason J, Tilly H, Millenson M, Offner F, Gabrail NY, Ganguly S, Ailawadhi S, Kasar S, Kater AP, Doorduijn JK, Gao L, Lager JJ, Wu B, Egile C, Kersten MJ.

Lancet Haematol. 2018 Apr;5(4):e170-e180. doi: 10.1016/S2352-3026(18)30030-9. Epub 2018 Mar 14. Erratum in: Lancet Haematol. 2018 Jun;5(6):e240.

PMID:
29550382
50.

Subtype assignment of CLL based on B-cell subset associated gene signatures from normal bone marrow - A proof of concept study.

Nørgaard CH, Jakobsen LH, Gentles AJ, Dybkær K, El-Galaly TC, Bødker JS, Schmitz A, Johansen P, Herold T, Spiekermann K, Brown JR, Klitgaard JL, Johnsen HE, Bøgsted M.

PLoS One. 2018 Mar 7;13(3):e0193249. doi: 10.1371/journal.pone.0193249. eCollection 2018.

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