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Items: 1 to 50 of 1739

1.

Obesity-linked suppression of membrane-bound O-Acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease.

Helsley RN, Venkateshwari V, Brown AL, Gromovsky AD, Schugar RC, Ramachandiran I, Fung K, Kabbany MN, Banerjee R, Neumann CK, Finney C, Pathak P, Danny O, Osborn LJ, Massey W, Zhang R, Kadam A, Sansbury BE, Pan C, Sacks J, Lee RG, Crooke RM, Graham MJ, Lemieux ME, Gogonea V, Kirwan JP, Allende DS, Civelek M, Fox PL, Rudel LL, Lusis AJ, Spite M, Brown JM.

Elife. 2019 Oct 17;8. pii: e49882. doi: 10.7554/eLife.49882. [Epub ahead of print]

2.

Hinge Region in DNA Packaging Terminase pUL15 of Herpes Simplex Virus: A Potential Allosteric Target for Antiviral Drugs.

Thaljeh LF, Rothschild JA, Naderi M, Coghill LM, Brown JM, Brylinski M.

Biomolecules. 2019 Oct 12;9(10). pii: E603. doi: 10.3390/biom9100603.

3.

Identification and Visualization of Functionally Important Domains and Residues in Herpes Simplex Virus Glycoprotein K(gK) Using a Combination of Phylogenetics and Protein Modeling.

Rider PJF, Coghill LM, Naderi M, Brown JM, Brylinski M, Kousoulas KG.

Sci Rep. 2019 Oct 10;9(1):14625. doi: 10.1038/s41598-019-50490-9.

4.

Correction to: Solochrome cyanine: A histological stain for cobalt-chromium wear particles in metal-on-metal periprosthetic tissues.

Papadimitriou-Olivgeri I, Brown JM, Kilpatrick AFR, Gill HS, Athanasou NA.

J Mater Sci Mater Med. 2019 Sep 25;30(9):110. doi: 10.1007/s10856-019-6312-0.

PMID:
31555914
5.

Defect-induced electronic states amplify the cellular toxicity of ZnO nanoparticles.

Persaud I, Raghavendra AJ, Paruthi A, Alsaleh NB, Minarchick VC, Roede JR, Podila R, Brown JM.

Nanotoxicology. 2019 Sep 25:1-17. doi: 10.1080/17435390.2019.1668067. [Epub ahead of print]

PMID:
31553248
6.

The Flick of a Switch: Conferring Survival Advantage to Breast Cancer Stem Cells Through Metabolic Plasticity.

Walsh HR, Cruickshank BM, Brown JM, Marcato P.

Front Oncol. 2019 Aug 20;9:753. doi: 10.3389/fonc.2019.00753. eCollection 2019. Review.

7.

Macrophage Exclusion after Radiation Therapy (MERT): A First in Human Phase I/II Trial using a CXCR4 Inhibitor in Glioblastoma.

Thomas RP, Nagpal S, Iv M, Soltys SG, Bertrand S, Pelpola JS, Ball RL, Yang J, Sundaram V, Lavezo JL, Born DE, Vogel H, Brown JM, Recht L.

Clin Cancer Res. 2019 Sep 19. pii: clincanres.1421.2019. doi: 10.1158/1078-0432.CCR-19-1421. [Epub ahead of print]

PMID:
31537527
8.
9.

Exposure to silver nanoparticles primes mast cells for enhanced activation through the high-affinity IgE receptor.

Alsaleh NB, Mendoza RP, Brown JM.

Toxicol Appl Pharmacol. 2019 Sep 5:114746. doi: 10.1016/j.taap.2019.114746. [Epub ahead of print]

PMID:
31494149
10.

Solochrome cyanine: A histological stain for cobalt-chromium wear particles in metal-on-metal periprosthetic tissues.

Papadimitriou-Olivgeri I, Brown JM, Kilpatrick AFR, Gill HS, Athanasou NA.

J Mater Sci Mater Med. 2019 Sep 6;30(9):103. doi: 10.1007/s10856-019-6304-0. Erratum in: J Mater Sci Mater Med. 2019 Sep 25;30(9):110.

11.

A mixed-methods pilot study to evaluate a collaborative anaesthetic and surgical training package for emergency surgical cricothyroidotomy.

Berwick RJ, Gauntlett W, Silverio SA, Wallace H, Mercer S, Brown JM, Sandars JE, Morton B, Groom P.

Anaesth Intensive Care. 2019 Jul;47(4):357-367. doi: 10.1177/0310057X19861978. Epub 2019 Aug 18. No abstract available.

PMID:
31423804
12.

Safety and efficacy of inactivated varicella zoster virus vaccine in immunocompromised patients with malignancies: a two-arm, randomised, double-blind, phase 3 trial.

Mullane KM, Morrison VA, Camacho LH, Arvin A, McNeil SA, Durrand J, Campbell B, Su SC, Chan ISF, Parrino J, Kaplan SS, Popmihajlov Z, Annunziato PW; V212 Protocol 011 Trial Team.

Lancet Infect Dis. 2019 Sep;19(9):1001-1012. doi: 10.1016/S1473-3099(19)30310-X. Epub 2019 Aug 6. Erratum in: Lancet Infect Dis. 2019 Aug 23;:.

PMID:
31399378
13.

Ligand Conjugated Multimeric siRNAs Enable Enhanced Uptake and Multiplexed Gene Silencing.

Brown JM, Dahlman JE, Neuman KK, Prata CAH, Krampert MC, Hadwiger PM, Vornlocher HP.

Nucleic Acid Ther. 2019 Oct;29(5):231-244. doi: 10.1089/nat.2019.0782. Epub 2019 Aug 8.

14.

Response of Liver Metabolic Pathways to Ketogenic Diet and Exercise Are Not Additive.

Huang TY, Goldsmith FR, Fuller SE, Simon J, Batdorf HM, Scott MC, Essajee NM, Brown JM, Burk DH, Morrison CD, Burke SJ, Collier JJ, Noland RC.

Med Sci Sports Exerc. 2019 Aug 5. doi: 10.1249/MSS.0000000000002105. [Epub ahead of print]

PMID:
31389908
15.

Multi-disciplinary training hubs in North West England: the training hub lead perspective.

Brown JM, Sandars JE, Nwolise C, Silverio SA, Agius S, Patel M, Mamelok J.

Educ Prim Care. 2019 Sep;30(5):289-294. doi: 10.1080/14739879.2019.1639553. Epub 2019 Jul 28.

PMID:
31354075
16.

Rethinking the role of the brain in glucose homeostasis and diabetes pathogenesis.

Brown JM, Scarlett JM, Schwartz MW.

J Clin Invest. 2019 Jul 22;129(8):3035-3037. doi: 10.1172/JCI130904. eCollection 2019 Jul 22. No abstract available.

17.

Silver nanoparticle immunomodulatory potential in absence of direct cytotoxicity in RAW 264.7 macrophages and MPRO 2.1 neutrophils.

Alsaleh NB, Minarchick VC, Mendoza RP, Sharma B, Podila R, Brown JM.

J Immunotoxicol. 2019 Dec;16(1):63-73. doi: 10.1080/1547691X.2019.1588928.

PMID:
31282784
18.

Monitoring Disease Progression With a Quantitative Severity Scale for Retinopathy of Prematurity Using Deep Learning.

Taylor S, Brown JM, Gupta K, Campbell JP, Ostmo S, Chan RVP, Dy J, Erdogmus D, Ioannidis S, Kim SJ, Kalpathy-Cramer J, Chiang MF; Imaging and Informatics in Retinopathy of Prematurity Consortium.

JAMA Ophthalmol. 2019 Jul 3. doi: 10.1001/jamaophthalmol.2019.2433. [Epub ahead of print]

PMID:
31268518
19.

A Quantitative Severity Scale for Retinopathy of Prematurity Using Deep Learning to Monitor Disease Regression After Treatment.

Gupta K, Campbell JP, Taylor S, Brown JM, Ostmo S, Chan RVP, Dy J, Erdogmus D, Ioannidis S, Kalpathy-Cramer J, Kim SJ, Chiang MF; Imaging and Informatics in Retinopathy of Prematurity Consortium.

JAMA Ophthalmol. 2019 Jul 3. doi: 10.1001/jamaophthalmol.2019.2442. [Epub ahead of print]

PMID:
31268499
20.

Engineered nanomaterials and oxidative stress: current understanding and future challenges.

Mendoza RP, Brown JM.

Curr Opin Toxicol. 2019 Feb;13:74-80. doi: 10.1016/j.cotox.2018.09.001. Epub 2018 Sep 7.

PMID:
31263794
21.

Perineuronal Net Formation during the Critical Period for Neuronal Maturation in the Hypothalamic Arcuate Nucleus.

Mirzadeh Z, Alonge KM, Cabrales E, Herranz-Pérez V, Scarlett JM, Brown JM, Hassouna R, Matsen ME, Nguyen HT, Garcia-Verdugo JM, Zeltser LM, Schwartz MW.

Nat Metab. 2019 Feb;1(2):212-221. doi: 10.1038/s42255-018-0029-0. Epub 2019 Jan 21.

22.

Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling.

Gimple RC, Kidwell RL, Kim LJY, Sun T, Gromovsky AD, Wu Q, Wolf M, Lv D, Bhargava S, Jiang L, Prager BC, Wang X, Ye Q, Zhu Z, Zhang G, Dong Z, Zhao L, Lee D, Bi J, Sloan AE, Mischel PS, Brown JM, Cang H, Huan T, Mack SC, Xie Q, Rich JN.

Cancer Discov. 2019 Sep;9(9):1248-1267. doi: 10.1158/2159-8290.CD-19-0061. Epub 2019 Jun 14.

PMID:
31201181
23.

Automatic assessment of glioma burden: A deep learning algorithm for fully automated volumetric and bi-dimensional measurement.

Chang K, Beers AL, Bai HX, Brown JM, Ly KI, Li X, Senders JT, Kavouridis VK, Boaro A, Su C, Bi WL, Rapalino O, Liao W, Shen Q, Zhou H, Xiao B, Wang Y, Zhang PJ, Pinho MC, Wen PY, Batchelor TT, Boxerman JL, Arnaout O, Rosen BR, Gerstner ER, Yang L, Huang RY, Kalpathy-Cramer J.

Neuro Oncol. 2019 Jun 13. pii: noz106. doi: 10.1093/neuonc/noz106. [Epub ahead of print]

PMID:
31190077
24.

Immunophenotypic expression of UCP1 in hibernoma and other adipose/non adipose soft tissue tumours.

Malzahn J, Kastrenopoulou A, Papadimitriou-Olivgeri I, Papachristou DJ, Brown JM, Oppermann U, Athanasou NA.

Clin Sarcoma Res. 2019 May 13;9:8. doi: 10.1186/s13569-019-0118-1. eCollection 2019.

25.

Evaluation of early radiation DNA damage in a fractal cell nucleus model using Geant4-DNA.

Sakata D, Lampe N, Karamitros M, Kyriakou I, Belov O, Bernal MA, Bolst D, Bordage MC, Breton V, Brown JMC, Francis Z, Ivanchenko V, Meylan S, Murakami K, Okada S, Petrovic I, Ristic-Fira A, Santin G, Sarramia D, Sasaki T, Shin WG, Tang N, Tran HN, Villagrasa C, Emfietzoglou D, Nieminen P, Guatelli S, Incerti S.

Phys Med. 2019 Jun;62:152-157. doi: 10.1016/j.ejmp.2019.04.010. Epub 2019 May 17.

PMID:
31109825
26.

Low-intensity exercise induces acute shifts in liver and skeletal muscle substrate metabolism but not chronic adaptations in tissue oxidative capacity.

Fuller SE, Huang TY, Simon J, Batdorf HM, Essajee NM, Scott MC, Waskom CM, Brown JM, Burke SJ, Collier JJ, Noland RC.

J Appl Physiol (1985). 2019 Jul 1;127(1):143-156. doi: 10.1152/japplphysiol.00820.2018. Epub 2019 May 16.

PMID:
31095457
27.

Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report.

Shih DM, Zhu W, Schugar RC, Meng Y, Jia X, Miikeda A, Wang Z, Zieger M, Lee R, Graham M, Allayee H, Cantor RM, Mueller C, Brown JM, Hazen SL, Lusis AJ.

Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1045-1054. doi: 10.1161/ATVBAHA.119.312592.

PMID:
31070450
28.

Early Proteome Shift and Serum Bioactivity Precede Diesel Exhaust-induced Impairment of Cardiovascular Recovery in Spontaneously Hypertensive Rats.

Thompson LC, Shannahan JH, Perez CM, Haykal-Coates N, King C, Hazari MS, Brown JM, Farraj AK.

Sci Rep. 2019 May 3;9(1):6885. doi: 10.1038/s41598-019-43339-8.

29.

Automated Fundus Image Quality Assessment in Retinopathy of Prematurity Using Deep Convolutional Neural Networks.

Coyner AS, Swan R, Campbell JP, Ostmo S, Brown JM, Kalpathy-Cramer J, Kim SJ, Jonas KE, Chan RVP, Chiang MF; Imaging and Informatics in Retinopathy of Prematurity Research Consortium.

Ophthalmol Retina. 2019 May;3(5):444-450. doi: 10.1016/j.oret.2019.01.015. Epub 2019 Jan 31.

PMID:
31044738
30.

Dynamin 2, cell trafficking, and the triple-negative paradox.

Chernikova SB, Game JC, Brown JM.

Oncotarget. 2019 Mar 22;10(24):2336-2337. doi: 10.18632/oncotarget.26778. eCollection 2019 Mar 22. No abstract available.

31.

Eremothecium coryli bloodstream infection in a patient with acute myeloid leukemia: first case report of human infection.

Multani A, Rustagi A, Epstein DJ, Gomez CA, Budvytiene I, Banaei N, Brown JM, Liu AY.

Diagn Microbiol Infect Dis. 2019 Sep;95(1):77-79. doi: 10.1016/j.diagmicrobio.2019.03.011. Epub 2019 Mar 27.

PMID:
31005402
32.

Patient-Reported Outcome Results From the Open-Label, Randomized Phase III Myeloma X Trial Evaluating Salvage Autologous Stem-Cell Transplantation in Relapsed Multiple Myeloma.

Ahmedzai SH, Snowden JA, Ashcroft AJ, Cairns DA, Williams C, Hockaday A, Cavenagh JD, Ademokun D, Tholouli E, Allotey D, Dhanapal V, Jenner M, Yong K, Cavet J, Hunter H, Bird JM, Pratt G, Parrish C, Brown JM, Morris TCM, Cook G; National Cancer Research Institute Haemato-Oncology Clinical Studies Group.

J Clin Oncol. 2019 Jul 1;37(19):1617-1628. doi: 10.1200/JCO.18.01006. Epub 2019 Apr 10.

33.

Systematic evaluation of Patient-Reported Outcome protocol content and reporting in cancer trials.

Kyte D, Retzer A, Ahmed K, Keeley T, Armes J, Brown JM, Calman L, Gavin A, Glaser AW, Greenfield DM, Lanceley A, Taylor RM, Velikova G, Brundage M, Efficace F, Mercieca-Bebber R, King MT, Turner G, Calvert M.

J Natl Cancer Inst. 2019 Apr 11. pii: djz038. doi: 10.1093/jnci/djz038. [Epub ahead of print]

34.

GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells.

Smith EL, Harrington K, Staehr M, Masakayan R, Jones J, Long TJ, Ng KY, Ghoddusi M, Purdon TJ, Wang X, Do T, Pham MT, Brown JM, De Larrea CF, Olson E, Peguero E, Wang P, Liu H, Xu Y, Garrett-Thomson SC, Almo SC, Wendel HG, Riviere I, Liu C, Sather B, Brentjens RJ.

Sci Transl Med. 2019 Mar 27;11(485). pii: eaau7746. doi: 10.1126/scitranslmed.aau7746.

PMID:
30918115
35.

Semi-quantitative electromyography as a predictor of nerve transfer outcome.

Mandeville RM, Brown JM, Sheean GL.

Clin Neurophysiol. 2019 May;130(5):701-706. doi: 10.1016/j.clinph.2019.02.008. Epub 2019 Feb 28.

PMID:
30875537
36.

Comparison of generic and disease-specific measures in their ability to detect differences in pressure ulcer clinical groups.

Rutherford C, Campbell R, Brown JM, Smith I, Costa DSJ, McGinnis E, Wilson L, Gilberts R, Brown S, Coleman S, Collier H, Nixon JE.

Wound Repair Regen. 2019 Jul;27(4):396-405. doi: 10.1111/wrr.12716. Epub 2019 Mar 30.

PMID:
30868673
37.

Deep Learning for Image Quality Assessment of Fundus Images in Retinopathy of Prematurity.

Coyner AS, Swan R, Brown JM, Kalpathy-Cramer J, Kim SJ, Campbell JP, Jonas KE, Ostmo S, Chan RVP, Chiang MF.

AMIA Annu Symp Proc. 2018 Dec 5;2018:1224-1232. eCollection 2018.

38.

Targeting the Post-Irradiation Tumor Microenvironment in Glioblastoma via Inhibition of CXCL12.

Giordano FA, Link B, Glas M, Herrlinger U, Wenz F, Umansky V, Brown JM, Herskind C.

Cancers (Basel). 2019 Feb 26;11(3). pii: E272. doi: 10.3390/cancers11030272. Review.

39.

The Hypothalamic Arcuate Nucleus-Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1.

Brown JM, Scarlett JM, Matsen ME, Nguyen HT, Secher AL, Jorgensen R, Morton GJ, Schwartz MW.

Diabetes. 2019 May;68(5):1054-1061. doi: 10.2337/db19-0025. Epub 2019 Feb 22.

PMID:
30796029
40.

An investigation into specialty trainee engagement with e-learning.

Brown JM, Kinloch K, Shaw NJ.

Br J Hosp Med (Lond). 2019 Feb 2;80(2):105-108. doi: 10.12968/hmed.2019.80.2.105.

PMID:
30746988
41.

Evidence for multiple dynamic climbing gait families.

Brown JM, Austin MP, Miller BD, Clark JE.

Bioinspir Biomim. 2019 Feb 11;14(3):036001. doi: 10.1088/1748-3190/aae420.

PMID:
30742587
42.

ISiCLE: A Quantum Chemistry Pipeline for Establishing in Silico Collision Cross Section Libraries.

Colby SM, Thomas DG, Nuñez JR, Baxter DJ, Glaesemann KR, Brown JM, Pirrung MA, Govind N, Teeguarden JG, Metz TO, Renslow RS.

Anal Chem. 2019 Apr 2;91(7):4346-4356. doi: 10.1021/acs.analchem.8b04567. Epub 2019 Mar 6.

PMID:
30741529
43.

The impact of cytogenetics on duration of response and overall survival in patients with relapsed multiple myeloma (long-term follow-up results from BSBMT/UKMF Myeloma X Relapse [Intensive]): a randomised, open-label, phase 3 trial.

Cook G, Royle KL, O'Connor S, Cairns DA, Ashcroft AJ, Williams CD, Hockaday A, Cavenagh JD, Snowden JA, Ademokun D, Tholouli E, Andrews VE, Jenner M, Parrish C, Yong K, Cavet J, Hunter H, Bird JM, Pratt G, Drayson MT, Brown JM, Morris TCM; National Cancer Research Institute Haemato-oncology Clinical Studies Group.

Br J Haematol. 2019 May;185(3):450-467. doi: 10.1111/bjh.15782. Epub 2019 Feb 6.

44.

Hydrogen Bonding Phase-Transfer Catalysis with Potassium Fluoride: Enantioselective Synthesis of β-Fluoroamines.

Pupo G, Vicini AC, Ascough DMH, Ibba F, Christensen KE, Thompson AL, Brown JM, Paton RS, Gouverneur V.

J Am Chem Soc. 2019 Feb 20;141(7):2878-2883. doi: 10.1021/jacs.8b12568. Epub 2019 Feb 4.

45.

Principles of Pediatric Patient Safety: Reducing Harm Due to Medical Care.

Mueller BU, Neuspiel DR, Fisher ERS; COUNCIL ON QUALITY IMPROVEMENT AND PATIENT SAFETY, COMMITTEE ON HOSPITAL CARE.

Pediatrics. 2019 Feb;143(2). pii: e20183649. doi: 10.1542/peds.2018-3649. Epub 2019 Jan 22.

PMID:
30670581
46.

Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions.

Teixeira VH, Pipinikas CP, Pennycuick A, Lee-Six H, Chandrasekharan D, Beane J, Morris TJ, Karpathakis A, Feber A, Breeze CE, Ntolios P, Hynds RE, Falzon M, Capitanio A, Carroll B, Durrenberger PF, Hardavella G, Brown JM, Lynch AG, Farmery H, Paul DS, Chambers RC, McGranahan N, Navani N, Thakrar RM, Swanton C, Beck S, George PJ, Spira A, Campbell PJ, Thirlwell C, Janes SM.

Nat Med. 2019 Mar;25(3):517-525. doi: 10.1038/s41591-018-0323-0. Epub 2019 Jan 21.

PMID:
30664780
47.

A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia.

Picariello T, Brown JM, Hou Y, Swank G, Cochran DA, King OD, Lechtreck K, Pazour GJ, Witman GB.

J Cell Sci. 2019 Feb 11;132(3). pii: jcs220749. doi: 10.1242/jcs.220749.

48.

Effects of Lifestyle Intervention on Plasma Trimethylamine N-Oxide in Obese Adults.

Erickson ML, Malin SK, Wang Z, Brown JM, Hazen SL, Kirwan JP.

Nutrients. 2019 Jan 16;11(1). pii: E179. doi: 10.3390/nu11010179.

49.

Disseminating technology in global surgery.

Bolton WS, Aruparayil N, Quyn A, Scott J, Wood A, Bundu I, Gnanaraj J, Brown JM, Jayne DG.

Br J Surg. 2019 Jan;106(2):e34-e43. doi: 10.1002/bjs.11036. Review.

PMID:
30620068
50.

Exercise-induced muscle damage on the contractile properties of the lumbar paraspinal muscles: a laser displacement mechanomyographic approach.

Than C, Roberts L, Coombes BK, Tosovic D, Brown JM.

Eur J Appl Physiol. 2019 Mar;119(3):761-770. doi: 10.1007/s00421-018-04067-5. Epub 2019 Jan 8.

PMID:
30617466

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