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Correlation of Thromboelastography with Apparent Rivaroxaban Concentration: Has Point-of-Care Testing Improved?

Myers SP, Dyer MR, Hassoune A, Brown JB, Sperry JL, Meyer MP, Rosengart MR, Neal MD.

Anesthesiology. 2020 Feb;132(2):280-290. doi: 10.1097/ALN.0000000000003061.


A comprehensive epigenomic analysis of phenotypically distinguishable, genetically identical female and male Daphnia pulex.

Kvist J, Athanàsio CG, Pfrender ME, Brown JB, Colbourne JK, Mirbahai L.

BMC Genomics. 2020 Jan 6;21(1):17. doi: 10.1186/s12864-019-6415-5.


Association of Prehospital Plasma Transfusion With Survival in Trauma Patients With Hemorrhagic Shock When Transport Times Are Longer Than 20 Minutes: A Post Hoc Analysis of the PAMPer and COMBAT Clinical Trials.

Pusateri AE, Moore EE, Moore HB, Le TD, Guyette FX, Chapman MP, Sauaia A, Ghasabyan A, Chandler J, McVaney K, Brown JB, Daley BJ, Miller RS, Harbrecht BG, Claridge JA, Phelan HA, Witham WR, Putnam AT, Sperry JL.

JAMA Surg. 2019 Dec 18:e195085. doi: 10.1001/jamasurg.2019.5085. [Epub ahead of print]


Correlation of Thromboelastography with Apparent Rivaroxaban Concentration: Has Point-of-Care Testing Improved?

Myers SP, Dyer MR, Hassoune A, Brown JB, Sperry JL, Meyer MP, Rosengart MR, Neal MD.

Anesthesiology. 2019 Dec 13. doi: 10.1097/ALN.0000000000003061. [Epub ahead of print]


Vision of a near future: Bridging the human health-environment divide. Toward an integrated strategy to understand mechanisms across species for chemical safety assessment.

Rivetti C, Allen TEH, Brown JB, Butler E, Carmichael PL, Colbourne JK, Dent M, Falciani F, Gunnarsson L, Gutsell S, Harrill JA, Hodges G, Jennings P, Judson R, Kienzler A, Margiotta-Casaluci L, Muller I, Owen SF, Rendal C, Russell PJ, Scott S, Sewell F, Shah I, Sorrel I, Viant MR, Westmoreland C, White A, Campos B.

Toxicol In Vitro. 2020 Feb;62:104692. doi: 10.1016/j.tiv.2019.104692. Epub 2019 Oct 25.


Prehospital plasma in injured patients is associated with survival principally in blunt injury: Results from two randomized prehospital plasma trials.

Reitz KM, Moore HB, Guyette FX, Sauaia A, Pusateri AE, Moore EE, Hassoune A, Chapman MP, Daley BJ, Miller RS, Harbrecht BG, Claridge JA, Phelan HA, Brown JB, Zuckerbraun BS, Neal MD, Yazer MH, Sperry JL.

J Trauma Acute Care Surg. 2020 Jan;88(1):33-41. doi: 10.1097/TA.0000000000002485.


Complete Genome Sequence of Agrobacterium sp. Strain 33MFTa1.1, Isolated from Thlaspi arvense Roots.

Langley S, Eng T, Wan KH, Herbert RA, Klein AP, Yoshikuni Y, Tringe SG, Brown JB, Celniker SE, Mortimer JC, Mukhopadhyay A.

Microbiol Resour Announc. 2019 Sep 12;8(37). pii: e00432-19. doi: 10.1128/MRA.00432-19.


An Exploratory Study of Children's Mental Health Providers' Perspectives on the Transition to Adult Care for Young Adolescents in the Canadian Context.

Schraeder KE, Reid GJ, Brown JB.

J Pediatr Nurs. 2019 Nov - Dec;49:51-59. doi: 10.1016/j.pedn.2019.08.015. Epub 2019 Sep 3.


Living With Hypoglycemia: An Exploration of Patients' Emotions: Qualitative Findings From the InHypo-DM Study, Canada.

Brown JB, Reichert SM, Valliere Y, Webster-Bogaert S, Ratzki-Leewing A, Ryan BL, Harris SB.

Diabetes Spectr. 2019 Aug;32(3):270-276. doi: 10.2337/ds18-0074.


Measuring Patients' Perceptions of Health Care Encounters: Examining the Factor Structure of the Revised Patient Perception of Patient-Centeredness (PPPC-R) Questionnaire.

Ryan BL, Brown JB, Tremblay PF, Stewart M.

J Patient Cent Res Rev. 2019 Jul 29;6(3):192-202. doi: 10.17294/2330-0698.1696. eCollection 2019 Summer.


Connecting People With Multimorbidity to Interprofessional Teams Using Telemedicine.

Pariser P, Pham TT, Brown JB, Stewart M, Charles J.

Ann Fam Med. 2019 Aug 12;17(Suppl 1):S57-S62. doi: 10.1370/afm.2379.


Applicability Domain of Active Learning in Chemical Probe Identification: Convergence in Learning from Non-Specific Compounds and Decision Rule Clarification.

Polash AH, Nakano T, Takeda S, Brown JB.

Molecules. 2019 Jul 26;24(15). pii: E2716. doi: 10.3390/molecules24152716.


Defining geographic emergency medical services coverage in trauma systems.

Brown JB, Rosengart MR, Peitzman AB, Billiar TR, Sperry JL.

J Trauma Acute Care Surg. 2019 Jul;87(1):92-99. doi: 10.1097/TA.0000000000002296.


Early versus late venous thromboembolism: A secondary analysis of data from the PROPPR trial.

Myers SP, Brown JB, Leeper CM, Kutcher ME, Chen X, Wade CE, Holcomb JB, Schreiber MA, Cardenas JC, Rosengart MR, Neal MD; PROPPR study group.

Surgery. 2019 Sep;166(3):416-422. doi: 10.1016/j.surg.2019.04.014. Epub 2019 Jun 21.


EcoFABs: advancing microbiome science through standardized fabricated ecosystems.

Zengler K, Hofmockel K, Baliga NS, Behie SW, Bernstein HC, Brown JB, Dinneny JR, Floge SA, Forry SP, Hess M, Jackson SA, Jansson C, Lindemann SR, Pett-Ridge J, Maranas C, Venturelli OS, Wallenstein MD, Shank EA, Northen TR.

Nat Methods. 2019 Jul;16(7):567-571. doi: 10.1038/s41592-019-0465-0. No abstract available.


International medical graduates and general practice training: How do educational leaders facilitate the transition from new migrant to local family doctor?

Wearne SM, Brown JB, Kirby C, Snadden D.

Med Teach. 2019 Sep;41(9):1065-1072. doi: 10.1080/0142159X.2019.1616681. Epub 2019 Jun 19.


Implementation of a prehospital air medical thawed plasma program: Is it even feasible?

Adams PW, Warren KA, Guyette FX, Yazer MH, Brown JB, Daily BJ, Miller RS, Harbrecht BG, Claridge JA, Phelan HA, Witham WR, Putnam AT, Zuckerbraun BS, Neal MD, Sperry JL; PAMPer study group.

J Trauma Acute Care Surg. 2019 Nov;87(5):1077-1081. doi: 10.1097/TA.0000000000002406.


Identifying patients with time-sensitive injuries: Association of mortality with increasing prehospital time.

Chen X, Guyette FX, Peitzman AB, Billiar TR, Sperry JL, Brown JB.

J Trauma Acute Care Surg. 2019 Jun;86(6):1015-1022. doi: 10.1097/TA.0000000000002251.


Predicting protein-ligand interactions based on bow-pharmacological space and Bayesian additive regression trees.

Li L, Koh CC, Reker D, Brown JB, Wang H, Lee NK, Liow HH, Dai H, Fan HM, Chen L, Wei DQ.

Sci Rep. 2019 May 22;9(1):7703. doi: 10.1038/s41598-019-43125-6.


Rhizobacteria Mediate the Phytotoxicity of a Range of Biorefinery-Relevant Compounds.

Herbert RA, Eng T, Martinez U, Wang B, Langley S, Wan K, Pidatala V, Hoffman E, Chen JC, Bissell MJ, Brown JB, Mukhopadhyay A, Mortimer JC.

Environ Toxicol Chem. 2019 Sep;38(9):1911-1922. doi: 10.1002/etc.4501. Epub 2019 Jul 26. Review.


Prehospital Blood Product and Crystalloid Resuscitation in the Severely Injured Patient: A Secondary Analysis of the Prehospital Air Medical Plasma Trial.

Guyette FX, Sperry JL, Peitzman AB, Billiar TR, Daley BJ, Miller RS, Harbrecht BG, Claridge JA, Putnam T, Duane TM, Phelan HA, Brown JB.

Ann Surg. 2019 Apr 13. doi: 10.1097/SLA.0000000000003324. [Epub ahead of print]


Geographical Disparity and Traumatic Brain Injury in America: Rural Areas Suffer Poorer Outcomes.

Brown JB, Kheng M, Carney NA, Rubiano AM, Puyana JC.

J Neurosci Rural Pract. 2019 Jan-Mar;10(1):10-15. doi: 10.4103/jnrp.jnrp_310_18.


Understanding compassion in family medicine: a qualitative study.

Uygur J, Brown JB, Herbert C.

Br J Gen Pract. 2019 Mar;69(680):e208-e216. doi: 10.3399/bjgp19X701285. Epub 2019 Jan 28.


Age-related remodelling of oesophageal epithelia by mutated cancer drivers.

Yokoyama A, Kakiuchi N, Yoshizato T, Nannya Y, Suzuki H, Takeuchi Y, Shiozawa Y, Sato Y, Aoki K, Kim SK, Fujii Y, Yoshida K, Kataoka K, Nakagawa MM, Inoue Y, Hirano T, Shiraishi Y, Chiba K, Tanaka H, Sanada M, Nishikawa Y, Amanuma Y, Ohashi S, Aoyama I, Horimatsu T, Miyamoto S, Tsunoda S, Sakai Y, Narahara M, Brown JB, Sato Y, Sawada G, Mimori K, Minamiguchi S, Haga H, Seno H, Miyano S, Makishima H, Muto M, Ogawa S.

Nature. 2019 Jan;565(7739):312-317. doi: 10.1038/s41586-018-0811-x. Epub 2019 Jan 2.


Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy.

Arbel H, Basu S, Fisher WW, Hammonds AS, Wan KH, Park S, Weiszmann R, Booth BW, Keranen SV, Henriquez C, Shams Solari O, Bickel PJ, Biggin MD, Celniker SE, Brown JB.

Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):900-908. doi: 10.1073/pnas.1808833115. Epub 2018 Dec 31.


The "Patient-centered coordination by a care team" questionnaire achieves satisfactory validity and reliability.

Ramond-Roquin A, Stewart M, Ryan BL, Richards M, Sussman J, Brown JB, Bouhali T, Bestard-Denommé L, Fortin M.

J Interprof Care. 2019 Sep-Oct;33(5):558-569. doi: 10.1080/13561820.2018.1554633. Epub 2018 Dec 17.


Pathologic Complete Response in a Large Gastric GIST: Using Molecular Markers to Achieve Maximal Response to Neoadjuvant Imatinib.

Brown JB, Pai RK, Burgess MA, Chennat J, Zureikat AH.

J Natl Compr Canc Netw. 2018 Dec;16(12):1424-1428. doi: 10.6004/jnccn.2018.7063.


Computational chemical biology on the rise.

Brown JB, Bajorath J.

Future Med Chem. 2019 Jan;11(1):1-3. doi: 10.4155/fmc-2018-0282. Epub 2018 Dec 10. Review. No abstract available.


Reconnaissance of Mixed Organic and Inorganic Chemicals in Private and Public Supply Tapwaters at Selected Residential and Workplace Sites in the United States.

Bradley PM, Kolpin DW, Romanok KM, Smalling KL, Focazio MJ, Brown JB, Cardon MC, Carpenter KD, Corsi SR, DeCicco LA, Dietze JE, Evans N, Furlong ET, Givens CE, Gray JL, Griffin DW, Higgins CP, Hladik ML, Iwanowicz LR, Journey CA, Kuivila KM, Masoner JR, McDonough CA, Meyer MT, Orlando JL, Strynar MJ, Weis CP, Wilson VS.

Environ Sci Technol. 2018 Dec 4;52(23):13972-13985. doi: 10.1021/acs.est.8b04622. Epub 2018 Nov 21.


The Future of Computational Chemogenomics.

Jacoby E, Brown JB.

Methods Mol Biol. 2018;1825:425-450. doi: 10.1007/978-1-4939-8639-2_15.


Selection of Informative Examples in Chemogenomic Datasets.

Reker D, Brown JB.

Methods Mol Biol. 2018;1825:369-410. doi: 10.1007/978-1-4939-8639-2_13.


Parsing Compound-Protein Bioactivity Tables.

Brown JB.

Methods Mol Biol. 2018;1825:131-170. doi: 10.1007/978-1-4939-8639-2_4.


Fundamental Bioinformatic and Chemoinformatic Data Processing.

Brown JB.

Methods Mol Biol. 2018;1825:95-129. doi: 10.1007/978-1-4939-8639-2_3.


Tranexamic acid administration is associated with an increased risk of posttraumatic venous thromboembolism.

Myers SP, Kutcher ME, Rosengart MR, Sperry JL, Peitzman AB, Brown JB, Neal MD.

J Trauma Acute Care Surg. 2019 Jan;86(1):20-27. doi: 10.1097/TA.0000000000002061.


Pattern of DNA Methylation in Daphnia: Evolutionary Perspective.

Kvist J, Gonçalves Athanàsio C, Shams Solari O, Brown JB, Colbourne JK, Pfrender ME, Mirbahai L.

Genome Biol Evol. 2018 Aug 1;10(8):1988-2007. doi: 10.1093/gbe/evy155.


Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock.

Sperry JL, Guyette FX, Brown JB, Yazer MH, Triulzi DJ, Early-Young BJ, Adams PW, Daley BJ, Miller RS, Harbrecht BG, Claridge JA, Phelan HA, Witham WR, Putnam AT, Duane TM, Alarcon LH, Callaway CW, Zuckerbraun BS, Neal MD, Rosengart MR, Forsythe RM, Billiar TR, Yealy DM, Peitzman AB, Zenati MS; PAMPer Study Group.

N Engl J Med. 2018 Jul 26;379(4):315-326. doi: 10.1056/NEJMoa1802345.


A qualitative enquiry of hypoglycemia and the social determinants of health: The InHypo-DM study, Canada.

Brown JB, Reichert SM, Valliere Y, Webster-Bogaert S, Ratzki-Leewing A, Harris SB.

Fam Syst Health. 2018 Dec;36(4):471-481. doi: 10.1037/fsh0000355. Epub 2018 Jul 12.


Blunt cerebrovascular injury in elderly fall patients: are we screening enough?

Anto VP, Brown JB, Peitzman AB, Zuckerbraun BS, Neal MD, Watson G, Forsythe R, Billiar TR, Sperry JL.

World J Emerg Surg. 2018 Jul 4;13:30. doi: 10.1186/s13017-018-0188-z. eCollection 2018.


Adaptive mining and model building of medicinal chemistry data with a multi-metric perspective.

Brown JB.

Future Med Chem. 2018 Aug 1;10(16):1885-1887. doi: 10.4155/fmc-2018-0188. Epub 2018 Jul 3. No abstract available.


An important class of intron retention events in human erythroblasts is regulated by cryptic exons proposed to function as splicing decoys.

Parra M, Booth BW, Weiszmann R, Yee B, Yeo GW, Brown JB, Celniker SE, Conboy JG.

RNA. 2018 Sep;24(9):1255-1265. doi: 10.1261/rna.066951.118. Epub 2018 Jun 29.


Processes that influence the evolution of family health teams.

Brown JB, Ryan BL.

Can Fam Physician. 2018 Jun;64(6):e283-e289.


Evolution and 15-year effect of a pan-Canadian training program: Transdisciplinary Understanding and Training on Research-Primary Health Care.

Terry AL, Brown JB, Van Hoorn R, Stewart M; TUTOR-PHC Program Co-Investigators.

Can Fam Physician. 2018 Jun;64(6):475-476. No abstract available.


Logistics of air medical transport: When and where does helicopter transport reduce prehospital time for trauma?

Chen X, Gestring ML, Rosengart MR, Peitzman AB, Billiar TR, Sperry JL, Brown JB.

J Trauma Acute Care Surg. 2018 Jul;85(1):174-181. doi: 10.1097/TA.0000000000001935.


Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain.

Takeuchi A, Iida K, Tsubota T, Hosokawa M, Denawa M, Brown JB, Ninomiya K, Ito M, Kimura H, Abe T, Kiyonari H, Ohno K, Hagiwara M.

Cell Rep. 2018 May 1;23(5):1326-1341. doi: 10.1016/j.celrep.2018.03.141.


Advancing drug discovery via GPU-based deep learning.

Gawehn E, Hiss JA, Brown JB, Schneider G.

Expert Opin Drug Discov. 2018 Jul;13(7):579-582. doi: 10.1080/17460441.2018.1465407. Epub 2018 Apr 18. No abstract available.


Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

Baillie JK, Bretherick A, Haley CS, Clohisey S, Gray A, Neyton LPA, Barrett J, Stahl EA, Tenesa A, Andersson R, Brown JB, Faulkner GJ, Lizio M, Schaefer U, Daub C, Itoh M, Kondo N, Lassmann T, Kawai J; IIBDGC Consortium, Mole D, Bajic VB, Heutink P, Rehli M, Kawaji H, Sandelin A, Suzuki H, Satsangi J, Wells CA, Hacohen N, Freeman TC, Hayashizaki Y, Carninci P, Forrest ARR, Hume DA.

PLoS Comput Biol. 2018 Mar 1;14(3):e1005934. doi: 10.1371/journal.pcbi.1005934. eCollection 2018 Mar.


The Emerging Role of Social Work in Primary Health Care: A Survey of Social Workers in Ontario Family Health Teams.

Ashcroft R, McMillan C, Ambrose-Miller W, McKee R, Brown JB.

Health Soc Work. 2018 May 1;43(2):109-117. doi: 10.1093/hsw/hly003.


Process evaluation of the HealtheSteps™ lifestyle prescription program.

Blunt W, Gill DP, Riggin B, Brown JB, Petrella RJ.

Transl Behav Med. 2019 Jan 1;9(1):32-40. doi: 10.1093/tbm/iby005.


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