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Items: 1 to 50 of 258

1.

Economic instability and household chaos relate to cortisol for children in poverty.

Brown ED, Anderson KE, Garnett ML, Hill EM.

J Fam Psychol. 2019 Jun 6. doi: 10.1037/fam0000545. [Epub ahead of print]

PMID:
31169392
2.

Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria.

Kattke MD, Gosschalk JE, Martinez OE, Kumar G, Gale RT, Cascio D, Sawaya MR, Philips M, Brown ED, Clubb RT.

PLoS Pathog. 2019 Apr 19;15(4):e1007723. doi: 10.1371/journal.ppat.1007723. eCollection 2019 Apr.

3.

A randomized controlled trial to assess operator radiation exposure from cardiac catheterization procedures using RAD BOARD® with standard pelvic shielding versus standard pelvic shielding alone.

Suryadevara R, Brown ED, Green SM, Scott TD, Nordberg CM, Blankenship JC.

Catheter Cardiovasc Interv. 2019 Mar 13. doi: 10.1002/ccd.28190. [Epub ahead of print]

PMID:
30866175
4.

High-Throughput Screening for Inhibitors of Wall Teichoic Acid Biosynthesis in Staphylococcus aureus.

El-Halfawy OM, Brown ED.

Methods Mol Biol. 2019;1954:297-308. doi: 10.1007/978-1-4939-9154-9_23.

PMID:
30864141
5.

A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria.

Stokes JM, Gutierrez A, Lopatkin AJ, Andrews IW, French S, Matic I, Brown ED, Collins JJ.

Nat Methods. 2019 Apr;16(4):303-306. doi: 10.1038/s41592-019-0333-y. Epub 2019 Mar 11.

PMID:
30858599
6.

Drug repurposing for antimicrobial discovery.

Farha MA, Brown ED.

Nat Microbiol. 2019 Apr;4(4):565-577. doi: 10.1038/s41564-019-0357-1. Epub 2019 Mar 4. Review.

PMID:
30833727
7.

A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium.

Ellis MJ, Tsai CN, Johnson JW, French S, Elhenawy W, Porwollik S, Andrews-Polymenis H, McClelland M, Magolan J, Coombes BK, Brown ED.

Nat Commun. 2019 Jan 14;10(1):197. doi: 10.1038/s41467-018-08190-x.

8.

Chemical-Chemical Combinations Map Uncharted Interactions in Escherichia coli under Nutrient Stress.

El Zahed SS, Brown ED.

iScience. 2018 Apr 27;2:168-181. doi: 10.1016/j.isci.2018.03.018. Epub 2018 Mar 27.

9.

Double-Loop Learning in Adaptive Management: The Need, the Challenge, and the Opportunity.

Williams BK, Brown ED.

Environ Manage. 2018 Dec;62(6):995-1006. doi: 10.1007/s00267-018-1107-5. Epub 2018 Sep 29.

10.

The potential for citizen science to produce reliable and useful information in ecology.

Brown ED, Williams BK.

Conserv Biol. 2019 Jun;33(3):561-569. doi: 10.1111/cobi.13223. Epub 2018 Nov 27.

PMID:
30242907
11.

Open-Source High-Throughput Phenomics of Bacterial Promoter-Reporter Strains.

French S, Coutts BE, Brown ED.

Cell Syst. 2018 Sep 26;7(3):339-346.e3. doi: 10.1016/j.cels.2018.07.004. Epub 2018 Aug 29.

PMID:
30172841
12.

Membrane activity profiling of small molecule B. subtilis growth inhibitors utilizing novel duel-dye fluorescence assay.

McAuley S, Huynh A, Czarny TL, Brown ED, Nodwell JR.

Medchemcomm. 2018 Feb 15;9(3):554-561. doi: 10.1039/c8md00009c. eCollection 2018 Mar 1.

13.

Broadened glycosylation patterning of heterologously produced erythromycin.

Fang L, Zhang G, El-Halfawy O, Simon M, Brown ED, Pfeifer BA.

Biotechnol Bioeng. 2018 Nov;115(11):2771-2777. doi: 10.1002/bit.26735. Epub 2018 Sep 15.

PMID:
29873068
14.

Nutrient Stress Small-Molecule Screening Platform for Escherichia coli.

El Zahed SS, Kumar G, Tong M, Brown ED.

Methods Mol Biol. 2018;1787:1-18. doi: 10.1007/978-1-4939-7847-2_1.

PMID:
29736706
15.

Meropenem potentiation of aminoglycoside activity against Pseudomonas aeruginosa: involvement of the MexXY-OprM multidrug efflux system.

Poole K, Gilmour C, Farha MA, Parkins MD, Klinoski R, Brown ED.

J Antimicrob Chemother. 2018 May 1;73(5):1247-1255. doi: 10.1093/jac/dkx539.

PMID:
29420743
16.

Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics.

MacNair CR, Stokes JM, Carfrae LA, Fiebig-Comyn AA, Coombes BK, Mulvey MR, Brown ED.

Nat Commun. 2018 Jan 31;9(1):458. doi: 10.1038/s41467-018-02875-z.

17.

Bicarbonate Alters Bacterial Susceptibility to Antibiotics by Targeting the Proton Motive Force.

Farha MA, French S, Stokes JM, Brown ED.

ACS Infect Dis. 2018 Mar 9;4(3):382-390. doi: 10.1021/acsinfecdis.7b00194. Epub 2018 Jan 4.

PMID:
29264917
18.

Silent but deadly: IS200 promotes pathogenicity in Salmonella Typhimurium.

Ellis MJ, Carfrae LA, Macnair CR, Trussler RS, Brown ED, Haniford DB.

RNA Biol. 2018 Feb 1;15(2):176-181. doi: 10.1080/15476286.2017.1403001. Epub 2017 Dec 8.

19.

B. subtilis LytR-CpsA-Psr Enzymes Transfer Wall Teichoic Acids from Authentic Lipid-Linked Substrates to Mature Peptidoglycan In Vitro.

Gale RT, Li FKK, Sun T, Strynadka NCJ, Brown ED.

Cell Chem Biol. 2017 Dec 21;24(12):1537-1546.e4. doi: 10.1016/j.chembiol.2017.09.006. Epub 2017 Oct 26.

20.

Exploiting the Sensitivity of Nutrient Transporter Deletion Strains in Discovery of Natural Product Antimetabolites.

Gehrke SS, Kumar G, Yokubynas NA, Côté JP, Wang W, French S, MacNair CR, Wright GD, Brown ED.

ACS Infect Dis. 2017 Dec 8;3(12):955-965. doi: 10.1021/acsinfecdis.7b00149. Epub 2017 Nov 7.

PMID:
29069544
21.

Use of genetic and chemical synthetic lethality as probes of complexity in bacterial cell systems.

Klobucar K, Brown ED.

FEMS Microbiol Rev. 2018 Jan 1;42(1). doi: 10.1093/femsre/fux054. Review.

PMID:
29069427
22.

Chemical genomics reveals mechanistic hypotheses for uncharacterized bioactive molecules in bacteria.

French S, Ellis MJ, Coutts BE, Brown ED.

Curr Opin Microbiol. 2017 Oct;39:42-47. doi: 10.1016/j.mib.2017.09.005. Epub 2017 Sep 26. Review.

PMID:
28957731
23.

MicroRNA-containing extracellular vesicles released from endothelial colony-forming cells modulate angiogenesis during ischaemic retinopathy.

Dellett M, Brown ED, Guduric-Fuchs J, O'Connor A, Stitt AW, Medina RJ, Simpson DA.

J Cell Mol Med. 2017 Dec;21(12):3405-3419. doi: 10.1111/jcmm.13251. Epub 2017 Jun 20.

24.

Bacteria Getting into Shape: Genetic Determinants of E. coli Morphology.

French S, Côté JP, Stokes JM, Truant R, Brown ED.

MBio. 2017 Mar 7;8(2). pii: e01977-16. doi: 10.1128/mBio.01977-16.

25.

Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance.

Stokes JM, MacNair CR, Ilyas B, French S, Côté JP, Bouwman C, Farha MA, Sieron AO, Whitfield C, Coombes BK, Brown ED.

Nat Microbiol. 2017 Mar 6;2:17028. doi: 10.1038/nmicrobiol.2017.28.

26.

Author Correction for Côté et al., The Genome-Wide Interaction Network of Nutrient Stress Genes in Escherichia coli.

Côté JP, French S, Gehrke SS, MacNair CR, Mangat CS, Bharat A, Brown ED.

MBio. 2016 Dec 20;7(6). pii: e02138-16. doi: 10.1128/mBio.02138-16. No abstract available.

27.

Recommendations for the Implementation of Telehealth in Cardiovascular and Stroke Care: A Policy Statement From the American Heart Association.

Schwamm LH, Chumbler N, Brown E, Fonarow GC, Berube D, Nystrom K, Suter R, Zavala M, Polsky D, Radhakrishnan K, Lacktman N, Horton K, Malcarney MB, Halamka J, Tiner AC; American Heart Association Advocacy Coordinating Committee.

Circulation. 2017 Feb 14;135(7):e24-e44. doi: 10.1161/CIR.0000000000000475. Epub 2016 Dec 20. Review.

PMID:
27998940
28.

Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance.

Sobhanifar S, Worrall LJ, King DT, Wasney GA, Baumann L, Gale RT, Nosella M, Brown ED, Withers SG, Strynadka NC.

PLoS Pathog. 2016 Dec 14;12(12):e1006067. doi: 10.1371/journal.ppat.1006067. eCollection 2016 Dec.

29.

Can the Arts Get Under the Skin? Arts and Cortisol for Economically Disadvantaged Children.

Brown ED, Garnett ML, Anderson KE, Laurenceau JP.

Child Dev. 2017 Jul;88(4):1368-1381. doi: 10.1111/cdev.12652. Epub 2016 Dec 6.

PMID:
27921313
30.

The Genome-Wide Interaction Network of Nutrient Stress Genes in Escherichia coli.

Côté JP, French S, Gehrke SS, MacNair CR, Mangat CS, Bharat A, Brown ED.

MBio. 2016 Nov 22;7(6). pii: e01714-16. doi: 10.1128/mBio.01714-16. Erratum in: MBio. 2016 Dec 20;7(6):.

31.

Applying the Resilient Health System Framework for Universal Health Coverage.

Ho K, Al-Shorjabji N, Brown E, Zelmer J, Gabor N, Maeder A, Marcelo A, Ritz D, Messina L, Loyola M, Abbott P, Nazira J, McKinnon A, Dissanayake V, Akeel A, Gardner N, Doyle T.

Stud Health Technol Inform. 2016;231:54-62.

PMID:
27782016
32.

Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component.

Myers CL, Li FK, Koo BM, El-Halfawy OM, French S, Gross CA, Strynadka NC, Brown ED.

J Biol Chem. 2016 Dec 9;291(50):26066-26082. Epub 2016 Oct 25.

33.

Systematic Genetic Screens Reveal the Dynamic Global Functional Organization of the Bacterial Translation Machinery.

Gagarinova A, Stewart G, Samanfar B, Phanse S, White CA, Aoki H, Deineko V, Beloglazova N, Yakunin AF, Golshani A, Brown ED, Babu M, Emili A.

Cell Rep. 2016 Oct 11;17(3):904-916. doi: 10.1016/j.celrep.2016.09.040.

34.

A cell-based approach to characterize antimicrobial compounds through kinetic dose response.

MacNair CR, Stokes JM, French S, Myers CL, Iyer KR, Brown ED.

Bioorg Med Chem. 2016 Dec 15;24(24):6315-6319. doi: 10.1016/j.bmc.2016.09.053. Epub 2016 Sep 22.

PMID:
27713016
35.

A mechanism for stroke complicating thrombus aspiration.

Brown ED, Blankenship JC.

Catheter Cardiovasc Interv. 2017 Jan;89(1):93-96. doi: 10.1002/ccd.26682. Epub 2016 Oct 3.

PMID:
27696665
36.

A Small-Molecule Screening Platform for the Discovery of Inhibitors of Undecaprenyl Diphosphate Synthase.

Czarny TL, Brown ED.

ACS Infect Dis. 2016 Jul 8;2(7):489-99. doi: 10.1021/acsinfecdis.6b00044. Epub 2016 May 24.

PMID:
27626101
37.

Zinc Chelation by a Small-Molecule Adjuvant Potentiates Meropenem Activity in Vivo against NDM-1-Producing Klebsiella pneumoniae.

Falconer SB, Reid-Yu SA, King AM, Gehrke SS, Wang W, Britten JF, Coombes BK, Wright GD, Brown ED.

ACS Infect Dis. 2015 Nov 13;1(11):533-43. doi: 10.1021/acsinfecdis.5b00033. Epub 2015 May 26.

PMID:
27623408
38.

Gram-Negative Resistance.

Brown ED.

ACS Infect Dis. 2015 Nov 13;1(11):507. doi: 10.1021/acsinfecdis.5b00123. No abstract available.

PMID:
27623405
39.

A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria.

Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CHS, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, Huang KC, Gross CA.

Cell. 2016 Jun 2;165(6):1493-1506. doi: 10.1016/j.cell.2016.05.003. Epub 2016 May 26.

40.

Potentiation of Aminoglycoside Activity in Pseudomonas aeruginosa by Targeting the AmgRS Envelope Stress-Responsive Two-Component System.

Poole K, Gilmour C, Farha MA, Mullen E, Lau CH, Brown ED.

Antimicrob Agents Chemother. 2016 May 23;60(6):3509-18. doi: 10.1128/AAC.03069-15. Print 2016 Jun.

41.

Cold Stress Makes Escherichia coli Susceptible to Glycopeptide Antibiotics by Altering Outer Membrane Integrity.

Stokes JM, French S, Ovchinnikova OG, Bouwman C, Whitfield C, Brown ED.

Cell Chem Biol. 2016 Feb 18;23(2):267-277. doi: 10.1016/j.chembiol.2015.12.011. Epub 2016 Feb 4.

42.

Assembly and clustering of natural antibiotics guides target identification.

Johnston CW, Skinnider MA, Dejong CA, Rees PN, Chen GM, Walker CG, French S, Brown ED, Bérdy J, Liu DY, Magarvey NA.

Nat Chem Biol. 2016 Apr;12(4):233-9. doi: 10.1038/nchembio.2018. Epub 2016 Feb 1.

PMID:
26829473
43.

Strategies for target identification of antimicrobial natural products.

Farha MA, Brown ED.

Nat Prod Rep. 2016 May 4;33(5):668-80. doi: 10.1039/c5np00127g. Review.

PMID:
26806527
44.

A robust platform for chemical genomics in bacterial systems.

French S, Mangat C, Bharat A, Côté JP, Mori H, Brown ED.

Mol Biol Cell. 2016 Mar 15;27(6):1015-25. doi: 10.1091/mbc.E15-08-0573. Epub 2016 Jan 20.

45.

Antibacterial drug discovery in the resistance era.

Brown ED, Wright GD.

Nature. 2016 Jan 21;529(7586):336-43. doi: 10.1038/nature17042. Review.

PMID:
26791724
46.

Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins.

King AM, King DT, French S, Brouillette E, Asli A, Alexander JA, Vuckovic M, Maiti SN, Parr TR Jr, Brown ED, Malouin F, Strynadka NC, Wright GD.

ACS Chem Biol. 2016 Apr 15;11(4):864-8. doi: 10.1021/acschembio.5b00944. Epub 2016 Jan 14.

PMID:
26731698
47.

Chemical modulators of ribosome biogenesis as biological probes.

Stokes JM, Brown ED.

Nat Chem Biol. 2015 Dec;11(12):924-32. doi: 10.1038/nchembio.1957. Epub 2015 Nov 17.

PMID:
26575239
48.

Editorial overview: Microbial systems biology.

Brown ED, Typas A.

Curr Opin Microbiol. 2015 Oct;27:viii-ix. doi: 10.1016/j.mib.2015.09.007. Epub 2015 Oct 20. No abstract available.

PMID:
26483052
49.

Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets.

Agbani EO, van den Bosch MT, Brown E, Williams CM, Mattheij NJ, Cosemans JM, Collins PW, Heemskerk JW, Hers I, Poole AW.

Circulation. 2015 Oct 13;132(15):1414-24. doi: 10.1161/CIRCULATIONAHA.114.015036. Epub 2015 Sep 1.

PMID:
26330411
50.

New chemical tools to probe cell wall biosynthesis in bacteria.

Gale RT, Brown ED.

Curr Opin Microbiol. 2015 Oct;27:69-77. doi: 10.1016/j.mib.2015.07.013. Epub 2015 Aug 25. Review.

PMID:
26291270

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